AR065097A1 - Preparacion solida - Google Patents

Preparacion solida

Info

Publication number
AR065097A1
AR065097A1 ARP080100381A ARP080100381A AR065097A1 AR 065097 A1 AR065097 A1 AR 065097A1 AR P080100381 A ARP080100381 A AR P080100381A AR P080100381 A ARP080100381 A AR P080100381A AR 065097 A1 AR065097 A1 AR 065097A1
Authority
AR
Argentina
Prior art keywords
solid preparation
sugar
excipient
methyl
salt
Prior art date
Application number
ARP080100381A
Other languages
English (en)
Inventor
Kenji Nakamura
Junya Nomura
Kenichiro Kiyoshima
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39240362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR065097(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of AR065097A1 publication Critical patent/AR065097A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Una preparacion solida caracterizada porque comprende las siguientes primera y segunda partes: (1) la primera parte que comprende 2-[[6-[(3R)-3-amino-1-piperidinil]-3,4-dihidro-3-metil-2,4-dioxo-1(2H)-pirimidinil]metil]-benzonitrilo o una sal del mismo y, como primer excipiente, azucar o alcohol de azucar; y (2) la segunda parte que comprende pioglitazona o una sal de la misma y, como el segundo excipiente, azucar o alcohol de azucar. Reivindicacion 2: La preparacion solida de la reivindicacion 1, caracterizado porque el azucar o alcohol de azucar es lactosa, sacarosa, eritritol o manitol.
ARP080100381A 2007-02-01 2008-01-30 Preparacion solida AR065097A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007023594 2007-02-01

Publications (1)

Publication Number Publication Date
AR065097A1 true AR065097A1 (es) 2009-05-13

Family

ID=39240362

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080100381A AR065097A1 (es) 2007-02-01 2008-01-30 Preparacion solida

Country Status (39)

Country Link
US (1) US8637079B2 (es)
EP (1) EP2107905B1 (es)
JP (1) JP5284968B2 (es)
KR (1) KR101486091B1 (es)
CN (1) CN101646420B (es)
AR (1) AR065097A1 (es)
AT (1) ATE488227T1 (es)
AU (1) AU2008211981B2 (es)
BR (1) BRPI0807453B8 (es)
CA (1) CA2677201C (es)
CL (1) CL2008000279A1 (es)
CR (1) CR10992A (es)
CY (1) CY1111264T1 (es)
DE (1) DE602008003522D1 (es)
DK (1) DK2107905T3 (es)
DO (1) DOP2009000195A (es)
EA (1) EA015180B1 (es)
EC (1) ECSP099608A (es)
ES (1) ES2354397T3 (es)
GE (1) GEP20125410B (es)
HK (1) HK1138188A1 (es)
HR (1) HRP20110094T8 (es)
IL (1) IL200108A (es)
JO (1) JO2650B1 (es)
MA (1) MA31169B1 (es)
ME (1) ME01239B (es)
MX (1) MX2009008100A (es)
MY (1) MY147596A (es)
NZ (1) NZ579008A (es)
PE (1) PE20081663A1 (es)
PL (1) PL2107905T3 (es)
PT (1) PT2107905E (es)
RS (1) RS51592B (es)
SI (1) SI2107905T1 (es)
TN (1) TN2009000317A1 (es)
TW (2) TWI453041B (es)
UA (1) UA95828C2 (es)
WO (1) WO2008093882A1 (es)
ZA (1) ZA200905621B (es)

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KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
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CN107115530A (zh) 2009-11-27 2017-09-01 勃林格殷格翰国际有限公司 基因型糖尿病患者利用dpp‑iv抑制剂例如利拉利汀的治疗
EP2547339A1 (en) 2010-03-18 2013-01-23 Boehringer Ingelheim International GmbH Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
AR082091A1 (es) * 2010-05-05 2012-11-14 Boehringer Ingelheim Int Composiciones farmaceuticas que comprenden pioglitazona y linagliptina y procedimiento de preparacion
AU2011249722B2 (en) 2010-05-05 2015-09-17 Boehringer Ingelheim International Gmbh Combination therapy
KR20220025926A (ko) 2010-06-24 2022-03-03 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
CN101912363A (zh) * 2010-07-29 2010-12-15 蔡海德 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
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KR101985384B1 (ko) 2011-07-15 2019-06-03 베링거 인겔하임 인터내셔날 게엠베하 치환된 퀴나졸린, 이의 제조 및 약제학적 조성물에서의 이의 용도
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CN103156819A (zh) * 2013-03-29 2013-06-19 山东罗欣药业股份有限公司 苯甲酸阿格列汀组合物片剂及其制备方法
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ−４阻害薬の医学的使用
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CN108289849A (zh) * 2015-06-26 2018-07-17 韩国联合制药株式会社 莫沙必利与雷贝拉唑的复合制剂
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Also Published As

Publication number Publication date
HRP20110094T1 (hr) 2011-03-31
CN101646420A (zh) 2010-02-10
BRPI0807453A2 (pt) 2014-05-20
KR101486091B1 (ko) 2015-01-23
AU2008211981A1 (en) 2008-08-07
EA015180B1 (ru) 2011-06-30
CR10992A (es) 2009-09-16
CL2008000279A1 (es) 2008-08-18
US20100092551A1 (en) 2010-04-15
JO2650B1 (en) 2012-06-17
GEP20125410B (en) 2012-02-27
MY147596A (en) 2012-12-31
HK1138188A1 (en) 2010-08-20
ES2354397T3 (es) 2011-03-14
MA31169B1 (fr) 2010-02-01
EP2107905B1 (en) 2010-11-17
EP2107905A1 (en) 2009-10-14
MX2009008100A (es) 2009-08-07
HRP20110094T8 (en) 2011-07-31
TWI453041B (zh) 2014-09-21
KR20090109115A (ko) 2009-10-19
DK2107905T3 (da) 2011-01-31
BRPI0807453B1 (pt) 2021-01-05
RS51592B (en) 2011-08-31
CN101646420B (zh) 2012-11-07
ME01239B (me) 2013-06-20
IL200108A0 (en) 2010-04-15
US8637079B2 (en) 2014-01-28
ECSP099608A (es) 2009-09-29
AU2008211981B2 (en) 2012-09-20
ATE488227T1 (de) 2010-12-15
CA2677201A1 (en) 2008-08-07
SI2107905T1 (sl) 2011-03-31
DE602008003522D1 (de) 2010-12-30
BRPI0807453B8 (pt) 2021-05-25
EA200970726A1 (ru) 2010-02-26
ZA200905621B (en) 2010-10-27
PE20081663A1 (es) 2008-12-25
NZ579008A (en) 2012-02-24
TW201350143A (zh) 2013-12-16
IL200108A (en) 2012-02-29
PL2107905T3 (pl) 2011-04-29
WO2008093882A1 (en) 2008-08-07
CA2677201C (en) 2015-11-17
TN2009000317A1 (en) 2010-12-31
DOP2009000195A (es) 2009-08-31
UA95828C2 (ru) 2011-09-12
JP5284968B2 (ja) 2013-09-11
CY1111264T1 (el) 2015-08-05
TW200836775A (en) 2008-09-16
PT2107905E (pt) 2010-12-17
JP2010517937A (ja) 2010-05-27

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