WO2007035372A3 - Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor - Google Patents

Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor Download PDF

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Publication number
WO2007035372A3
WO2007035372A3 PCT/US2006/035701 US2006035701W WO2007035372A3 WO 2007035372 A3 WO2007035372 A3 WO 2007035372A3 US 2006035701 W US2006035701 W US 2006035701W WO 2007035372 A3 WO2007035372 A3 WO 2007035372A3
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Prior art keywords
methyl
polymorphs
methods
benzonitrile
dioxo
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PCT/US2006/035701
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French (fr)
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WO2007035372A2 (en
Inventor
Mark Andres
Keith Lorimer
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Takeda Pharmaceutical
Mark Andres
Keith Lorimer
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Publication date
Priority to EP06803516A priority Critical patent/EP1934198B1/en
Priority to NZ566798A priority patent/NZ566798A/en
Priority to CA002622698A priority patent/CA2622698A1/en
Priority to AT06803516T priority patent/ATE518851T1/en
Priority to AU2006292637A priority patent/AU2006292637A1/en
Priority to BRPI0616215-0A priority patent/BRPI0616215A2/en
Application filed by Takeda Pharmaceutical, Mark Andres, Keith Lorimer filed Critical Takeda Pharmaceutical
Priority to EA200800728A priority patent/EA015359B1/en
Priority to JP2008531290A priority patent/JP5124464B2/en
Publication of WO2007035372A2 publication Critical patent/WO2007035372A2/en
Publication of WO2007035372A3 publication Critical patent/WO2007035372A3/en
Priority to IL190170A priority patent/IL190170A0/en
Priority to NO20081581A priority patent/NO20081581L/en

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Abstract

Compositions comprising Compound (I), wherein the Compound (I) is present in one or more polymorphic forms. Also provided are kits and articles of manufacture with compositions comprising one or more polymorphs of Compound (I), and methods of using the compositions to treat various diseases.
PCT/US2006/035701 2005-09-16 2006-09-13 Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor WO2007035372A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
NZ566798A NZ566798A (en) 2005-09-16 2006-09-13 Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
CA002622698A CA2622698A1 (en) 2005-09-16 2006-09-13 Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
AT06803516T ATE518851T1 (en) 2005-09-16 2006-09-13 POLYMORPHS OF THE BENZOATE SALT OF 2-ÄÄ6-Ä(3R)-3-
AU2006292637A AU2006292637A1 (en) 2005-09-16 2006-09-13 Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
BRPI0616215-0A BRPI0616215A2 (en) 2005-09-16 2006-09-13 2 - [[6 - [(3r) -3-amino-1-piperidinyl] -3,4-dihydro-3-methyl-2,4-dioxo-1 (2h) -pyrimidinyl] methyl benzoate salt polymorphs ] -benzonitrile and methods of use of these
EP06803516A EP1934198B1 (en) 2005-09-16 2006-09-13 Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
EA200800728A EA015359B1 (en) 2005-09-16 2006-09-13 Methods for preparing polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile
JP2008531290A JP5124464B2 (en) 2005-09-16 2006-09-13 Benzo of 2-[[6-[(3R) -3-amino-1-piperidinyl] -3,4-dihydro-3-methyl-2,4-dioxo-1 (2H) -pyrimidinyl] methyl] -benzonitrile Polymorphs of acid salts and methods for their use
IL190170A IL190170A0 (en) 2005-09-16 2008-03-13 Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl] methyl]-benzonitrile and methods of use therefor
NO20081581A NO20081581L (en) 2005-09-16 2008-03-31 Polymorphs of benzoate salt of 2 - [[6 - [(3R) -3-amino-1-piperidinyl] -3,4-dihydro-3-methyl-2,4-dioxo-1 (2H) -pyrimidinyl] methyl) benzonitrile, and methods of use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71813305P 2005-09-16 2005-09-16
US60/718,133 2005-09-16

Publications (2)

Publication Number Publication Date
WO2007035372A2 WO2007035372A2 (en) 2007-03-29
WO2007035372A3 true WO2007035372A3 (en) 2007-06-14

Family

ID=37758695

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/035701 WO2007035372A2 (en) 2005-09-16 2006-09-13 Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor

Country Status (21)

Country Link
US (1) US20070066635A1 (en)
EP (1) EP1934198B1 (en)
JP (1) JP5124464B2 (en)
KR (1) KR20080056183A (en)
CN (1) CN101360735A (en)
AR (1) AR056518A1 (en)
AT (1) ATE518851T1 (en)
AU (1) AU2006292637A1 (en)
BR (1) BRPI0616215A2 (en)
CA (1) CA2622698A1 (en)
CR (1) CR9881A (en)
EA (1) EA015359B1 (en)
GE (1) GEP20115171B (en)
IL (1) IL190170A0 (en)
MA (1) MA29800B1 (en)
NO (1) NO20081581L (en)
NZ (1) NZ566798A (en)
PE (1) PE20070766A1 (en)
TW (1) TW200745079A (en)
WO (1) WO2007035372A2 (en)
ZA (1) ZA200802856B (en)

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