NO20074431L - Pyrrolopyrimidiner nyttige som proteinkinaseinhibitorer - Google Patents

Pyrrolopyrimidiner nyttige som proteinkinaseinhibitorer

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Publication number
NO20074431L
NO20074431L NO20074431A NO20074431A NO20074431L NO 20074431 L NO20074431 L NO 20074431L NO 20074431 A NO20074431 A NO 20074431A NO 20074431 A NO20074431 A NO 20074431A NO 20074431 L NO20074431 L NO 20074431L
Authority
NO
Norway
Prior art keywords
protein kinase
kinase inhibitors
useful
pyrrolopyrimidines
pyrrolopyrimidines useful
Prior art date
Application number
NO20074431A
Other languages
English (en)
Inventor
Francesco Gerald Salituro
Guy W Bemis
Luc J Farmer
David Messersmith
Tiansheng Wang
Jian Wang
Mark W Ledeboer
Albert C Pierce
John P Duffy
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20074431L publication Critical patent/NO20074431L/no

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
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  • Ophthalmology & Optometry (AREA)
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  • Urology & Nephrology (AREA)
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Abstract

Foreliggende oppfinnelse vedrører forbindelser med formel (I) som er nyttige som inhibitorer av proteinkinaser. Oppfinnelsen tilveiebringer også farmasøytisk akseptable sammensetninger omfattende nevnte forbindelser og metoder for å anvende sammensetningene i behandlingen av forskjellige sykdommer, tilstander eller forstyrrelser.
NO20074431A 2005-02-03 2007-08-31 Pyrrolopyrimidiner nyttige som proteinkinaseinhibitorer NO20074431L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64978105P 2005-02-03 2005-02-03
PCT/US2006/004019 WO2006096270A1 (en) 2005-02-03 2006-02-02 Pyrrolopyrimidines useful as inhibitors of protein kinase

Publications (1)

Publication Number Publication Date
NO20074431L true NO20074431L (no) 2007-08-31

Family

ID=36498734

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074431A NO20074431L (no) 2005-02-03 2007-08-31 Pyrrolopyrimidiner nyttige som proteinkinaseinhibitorer

Country Status (16)

Country Link
US (2) US8633205B2 (no)
EP (1) EP1844050B1 (no)
JP (2) JP5227032B2 (no)
KR (1) KR20070104641A (no)
CN (1) CN101142218B (no)
AT (1) ATE420883T1 (no)
AU (1) AU2006221065A1 (no)
CA (1) CA2596830A1 (no)
DE (1) DE602006004844D1 (no)
ES (1) ES2320487T3 (no)
IL (1) IL184898A0 (no)
MX (1) MX2007009429A (no)
NO (1) NO20074431L (no)
RU (1) RU2434871C2 (no)
WO (1) WO2006096270A1 (no)
ZA (1) ZA200707342B (no)

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CL2009001884A1 (es) * 2008-10-02 2010-05-14 Incyte Holdings Corp Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
TWI665200B (zh) 2009-01-15 2019-07-11 英塞特公司 製造ｊａｋ抑制劑之方法及相關中間化合物
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PL2401267T3 (pl) * 2009-02-27 2014-06-30 Ambit Biosciences Corp Pochodne chinazoliny modulujące kinazę JAK i ich zastosowanie w metodach
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EP2451813B1 (en) 2009-07-08 2014-10-01 Leo Pharma A/S Heterocyclic compounds as jak receptor and protein tyrosine kinase inhibitors
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