JP2017535266A - 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法 - Google Patents

筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法 Download PDF

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JP2017535266A
JP2017535266A JP2017525847A JP2017525847A JP2017535266A JP 2017535266 A JP2017535266 A JP 2017535266A JP 2017525847 A JP2017525847 A JP 2017525847A JP 2017525847 A JP2017525847 A JP 2017525847A JP 2017535266 A JP2017535266 A JP 2017535266A
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sod1
sirna
vector
aav
als
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JP2017535266A5 (enExample
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ウェン‐イー サー、ディナー
ウェン‐イー サー、ディナー
ホウ、ジンジャオ
イー． ノンネンマッチャー、マシュー
イー． ノンネンマッチャー、マシュー
ジョウ、ペンチェン
ホスバッハ、マルクス
デッカート、ヨヘン
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Voyager Therapeutics Inc
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Voyager Therapeutics Inc
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Publication of JP2017535266A publication Critical patent/JP2017535266A/ja
Publication of JP2017535266A5 publication Critical patent/JP2017535266A5/ja
Priority to JP2022030717A priority Critical patent/JP2022081546A/ja
Priority to JP2024050822A priority patent/JP2024079794A/ja
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JP2017525847A 2014-11-14 2015-11-13 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法 Pending JP2017535266A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022030717A JP2022081546A (ja) 2014-11-14 2022-03-01 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法
JP2024050822A JP2024079794A (ja) 2014-11-14 2024-03-27 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法

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Application Number Priority Date Filing Date Title
US201462079588P 2014-11-14 2014-11-14
US62/079,588 2014-11-14
US201562211992P 2015-08-31 2015-08-31
US62/211,992 2015-08-31
US201562234466P 2015-09-29 2015-09-29
US62/234,466 2015-09-29
PCT/US2015/060562 WO2016077687A1 (en) 2014-11-14 2015-11-13 Compositions and methods of treating amyotrophic lateral sclerosis (als)

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JP2020159246A Division JP2021007394A (ja) 2014-11-14 2020-09-24 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法
JP2022030717A Division JP2022081546A (ja) 2014-11-14 2022-03-01 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法

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JP2017535266A5 JP2017535266A5 (enExample) 2018-10-25

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JP2017525847A Pending JP2017535266A (ja) 2014-11-14 2015-11-13 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法
JP2020159246A Pending JP2021007394A (ja) 2014-11-14 2020-09-24 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法
JP2022030717A Pending JP2022081546A (ja) 2014-11-14 2022-03-01 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法
JP2024050822A Pending JP2024079794A (ja) 2014-11-14 2024-03-27 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法

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JP2022030717A Pending JP2022081546A (ja) 2014-11-14 2022-03-01 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法
JP2024050822A Pending JP2024079794A (ja) 2014-11-14 2024-03-27 筋萎縮性側索硬化症（ａｌｓ）を治療する組成物および方法

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US (5) US10597660B2 (enExample)
EP (1) EP3218484A4 (enExample)
JP (4) JP2017535266A (enExample)
KR (2) KR102599909B1 (enExample)
CN (2) CN107109407A (enExample)
AU (2) AU2015346162B2 (enExample)
CA (2) CA3193811A1 (enExample)
HK (1) HK1244299A1 (enExample)
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Cited By (5)

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WO2019132624A1 (ko) * 2017-12-29 2019-07-04 주식회사 헬릭스미스 하이브리드 hgf 유전자가 도입된 aav(아데노-연관 바이러스) 벡터
KR20210131992A (ko) * 2018-12-14 2021-11-03 바이오젠 엠에이 인코포레이티드 근위축 측삭 경화증의 치료 및 방지를 위한 조성물 및 방법
JP2021529513A (ja) * 2018-07-02 2021-11-04 ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 筋萎縮性側索硬化症および脊髄に関連する障害の治療
JP2023537980A (ja) * 2020-08-12 2023-09-06 ユーシービー バイオファルマ エスアールエル メチルｃｐｇ結合タンパク質２（ｍｅｃｐ２）プロモータ配列を含む核酸構築体を用いた遺伝子治療
US12116589B2 (en) 2017-10-16 2024-10-15 Voyager Therapeutics, Inc. Treatment of amyotrophic lateral sclerosis (ALS)

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MX2017006216A (es) 2014-11-14 2018-08-29 Voyager Therapeutics Inc Composiciones y métodos para tratar la esclerosis lateral amiotrófica (ela).
AU2017268382B2 (en) 2016-05-18 2023-09-28 Voyager Therapeutics, Inc. Compositions and methods of treating Huntington's disease
EP3458588B1 (en) 2016-05-18 2025-10-29 Voyager Therapeutics, Inc. Modulatory polynucleotides
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CN111108198A (zh) * 2017-05-05 2020-05-05 沃雅戈治疗公司 治疗亨廷顿病的组合物和方法
CN118910166A (zh) * 2017-05-05 2024-11-08 沃雅戈治疗公司 调节性多核苷酸
EP3618839A4 (en) 2017-05-05 2021-06-09 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (als)
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KR20200075865A (ko) * 2017-10-23 2020-06-26 프리베일 테라퓨틱스, 인크. 신경변성 질환에 대한 유전자 요법
JP7350019B2 (ja) * 2018-05-31 2023-09-25 イミュニティ ファルマ リミテッド 筋萎縮性側索硬化症（ａｌｓ）を治療するための組成物、及び治療のためにそれを使用する方法
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JP2021530548A (ja) 2018-07-24 2021-11-11 ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics, Inc. 遺伝子治療製剤を生産するための系および方法
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TW202028468A (zh) 2018-10-15 2020-08-01 美商航海家醫療公司 用於桿狀病毒/Sf9系統中rAAV之大規模生產的表現載體
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EP3892283A1 (en) * 2020-04-09 2021-10-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Nucleic acids encoding human fus protein and use in the treatment of amyotrophic lateral sclerosis (als)
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EP4430191A2 (en) * 2021-11-08 2024-09-18 University Of Massachusetts Oligonucleotides for sod1 modulation
EP4540390A2 (en) * 2022-06-15 2025-04-23 Arrowhead Pharmaceuticals, Inc. Rnai agents for inhibiting expression of superoxide dismutase 1 (sod1), compositions thereof, and methods of use
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CN116270704A (zh) * 2023-02-24 2023-06-23 西交利物浦大学 一种抑制sod1基因表达的药物组合物及其应用
WO2024226761A2 (en) 2023-04-26 2024-10-31 Voyager Therapeutics, Inc. Compositions and methods for treating amyotrophic lateral sclerosis
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