AU4645697A
(en)
|
1996-09-11 |
1998-04-02 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Aav4 vector and uses thereof
|
US6759237B1
(en)
*
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
ES2340230T3
(es)
|
1998-11-10 |
2010-05-31 |
University Of North Carolina At Chapel Hill |
Vectores viricos y sus procedimientos de preparacion y administracion.
|
US6627617B1
(en)
|
1999-10-01 |
2003-09-30 |
University Of North Carolina At Chapel Hill |
Temperature-sensitive regulation of viral vector production
|
US6506600B2
(en)
|
2000-03-22 |
2003-01-14 |
University Of Arkansas |
Secreting products from skin by adeno-associated virus (AAV) gene transfer
|
US6855314B1
(en)
*
|
2000-03-22 |
2005-02-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector for transducing brain cells and lung cells
|
AU2001255575B2
(en)
*
|
2000-04-28 |
2006-08-31 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
|
EP1381276A4
(de)
*
|
2001-04-13 |
2005-02-02 |
Univ Pennsylvania |
Verfahren zur behandlung oder zur entwicklungsverlangsamung von blindheit
|
DE10120265A1
(de)
*
|
2001-04-25 |
2002-11-14 |
Deutsches Krebsforsch |
AAV-Helferplasmide zur Helfervirus-freien Verpackung und Pseudotypisierung von AAV-Vektoren
|
US7271150B2
(en)
|
2001-05-14 |
2007-09-18 |
United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Modified growth hormone
|
US8241622B2
(en)
|
2001-07-13 |
2012-08-14 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors with intravector heterologous terminal palindromic sequences
|
NZ578982A
(en)
|
2001-11-13 |
2011-03-31 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
|
ES2975413T3
(es)
|
2001-12-17 |
2024-07-05 |
Univ Pennsylvania |
Secuencias de serotipo 8 de virus adenoasociado (AAV), vectores que las contienen y usos de las mismas
|
JP4769417B2
(ja)
|
2001-12-17 |
2011-09-07 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
アデノ随伴ウイルス(aav)血清型9の配列、それを含むベクターおよびその使用
|
US7419817B2
(en)
|
2002-05-17 |
2008-09-02 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
|
US8927269B2
(en)
|
2003-05-19 |
2015-01-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Avian adenoassociated virus and uses thereof
|
JP4863874B2
(ja)
*
|
2003-09-01 |
2012-01-25 |
アカデミッシュ メディッシュ セントラム |
関節リウマチのインビボ遺伝子治療のためのaavベクター
|
US8529885B2
(en)
|
2003-09-01 |
2013-09-10 |
Academisch Medisch Centrum |
AAV vectors for in vivo gene therapy of rheumatoid arthritis
|
ES2648241T3
(es)
|
2003-09-30 |
2017-12-29 |
The Trustees Of The University Of Pennsylvania |
Clados de virus adenoasociados (AAV), secuencias, vectores que contienen el mismo, y usos de los mismos
|
US8137960B2
(en)
|
2003-12-04 |
2012-03-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Bovine adeno-associated viral (BAAV) vector and uses thereof
|
JP5060134B2
(ja)
|
2003-12-12 |
2012-10-31 |
ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ・アズ リプレゼンテッド バイ ザ セクレタリー・デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
ヒト細胞傷害性Tリンパ球のエピトープ及びそのMUC−1の非VNTR(non−variablenumberoftandemrepeatsequence)由来のアゴニストエピトープ
|
WO2006029196A1
(en)
*
|
2004-09-08 |
2006-03-16 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of H Ealth |
Transcytosis of adeno-associated viruses
|
NZ555830A
(en)
|
2004-12-15 |
2009-01-31 |
Univ North Carolina |
Chimeric vectors
|
US8999678B2
(en)
|
2005-04-07 |
2015-04-07 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an AAV vector
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
WO2007109583A2
(en)
|
2006-03-17 |
2007-09-27 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
EP2396343B1
(de)
|
2009-02-11 |
2017-05-17 |
The University of North Carolina At Chapel Hill |
Modifizierte virusvektoren sowie verfahren zu ihrer herstellung und verwendung
|
CN102448501A
(zh)
|
2009-03-27 |
2012-05-09 |
西马生物医学计划公司 |
治疗肝硬化和肝纤维化的方法和组合物
|
US8734809B2
(en)
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
BR112012010755A2
(pt)
|
2009-11-05 |
2015-09-22 |
Proyecto Biomedicina Cima Sl |
constructo de gene que permite a expressão hepato-específica induzível de um polinucleotídeo de interesse em resposta a um agente indutor, vetor, genoma viral recombinante, vírion, método in vitro para a expressão de um polinucleotídeo de interesse em uma célula de origem hepática, composição farmacêutica e operador-promotor bi-direcional induzível adequado para a expressão hepato-específica induzível de dois polinucleotídeos de interesse por um agente indutor
|
EP2524037B1
(de)
|
2010-01-12 |
2018-05-16 |
The University Of North Carolina At Chapel Hill |
Restriktive umgekehrte endverstärkungen für virusvektoren
|
EP2561073B1
(de)
|
2010-04-23 |
2016-08-24 |
University of Massachusetts |
Auf das zentralnervensystem abzielende vektoren und verfahren zu ihrer verwendung
|
US9272053B2
(en)
|
2010-04-23 |
2016-03-01 |
University Of Massachusetts |
AAV-based treatment of cholesterol-related disorders
|
CA2833905C
(en)
|
2010-04-23 |
2019-09-10 |
University Of Massachusetts |
Multicistronic expression constructs
|
EA202091105A1
(ru)
*
|
2010-04-23 |
2020-12-30 |
Юниверсити Оф Флорида Рисерч Фаундейшн, Инк. |
Композиции гуанилатциклазы и способы лечения врожденного амавроза лебера типа 1 (lca1)
|
US9309534B2
(en)
|
2010-07-12 |
2016-04-12 |
Universidad Autonoma De Barcelona |
Gene therapy composition for use in diabetes treatment
|
ES2661680T3
(es)
|
2011-04-21 |
2018-04-03 |
University Of Massachusetts |
Composiciones basadas en VAAr y métodos para tratar deficiencias de alfa-1 anti-tripsina
|
RS62795B1
(sr)
|
2011-04-22 |
2022-02-28 |
Univ California |
Adeno-povezani virioni virusa sa varijantama kapsida i postupci za njihovu primenu
|
AU2013221615B2
(en)
*
|
2012-02-14 |
2018-02-22 |
The Regents Of The University Of California |
Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions
|
EP2692868A1
(de)
|
2012-08-02 |
2014-02-05 |
Universitat Autònoma De Barcelona |
Adenoassoziierte virale (AAV) Vektoren für die Transduktion von Fettgewebe
|
PL2900686T3
(pl)
|
2012-09-28 |
2021-01-25 |
The University Of North Carolina At Chapel Hill |
Wektory aav ukierunkowane na oligodendrocyty
|
EP3763810A3
(de)
|
2012-10-10 |
2021-07-14 |
Sangamo Therapeutics, Inc. |
T-zell-modifizierende verbindungen und verwendungen davon
|
WO2014143932A1
(en)
|
2013-03-15 |
2014-09-18 |
The University Of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
EP3008191A2
(de)
|
2013-06-13 |
2016-04-20 |
Shire Human Genetic Therapies, Inc. |
Virenproduktion auf messenger-rna-basis
|
EP4039813A1
(de)
*
|
2013-07-12 |
2022-08-10 |
The Children's Hospital of Philadelphia |
Aav-vektor und assay für anti-aav (adeno-assoziierter virus)-neutralisierende antikörper
|
US20160354489A1
(en)
|
2013-09-26 |
2016-12-08 |
Universitat Autònome de Barcelona |
Gene therapy compositions for use in the prevention and/or treatment of non-alcoholic fatty liver disease
|
WO2015119941A2
(en)
|
2014-02-04 |
2015-08-13 |
Igenomx International Genomics Corporation |
Genome fractioning
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
US10072251B2
(en)
|
2014-02-19 |
2018-09-11 |
University Of Massachusetts |
Recombinant AAVS having useful transcytosis properties
|
PL3116900T3
(pl)
|
2014-03-09 |
2021-03-08 |
The Trustees Of The University Of Pennsylvania |
Kompozycje użyteczne w leczeniu niedoboru transkarbamylazy ornitynowej (otc)
|
EP4410805A2
(de)
|
2014-03-18 |
2024-08-07 |
University of Massachusetts |
Zusammensetzungen und verfahren zur behandlung von amyotropher lateralsklerose
|
WO2015164786A1
(en)
|
2014-04-25 |
2015-10-29 |
University Of Massachusetts |
Recombinant aav vectors useful for reducing immunity against transgene products
|
US10689653B2
(en)
|
2014-06-03 |
2020-06-23 |
University Of Massachusetts |
Compositions and methods for modulating dysferlin expression
|
US10577627B2
(en)
|
2014-06-09 |
2020-03-03 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
US9458464B2
(en)
|
2014-06-23 |
2016-10-04 |
The Johns Hopkins University |
Treatment of neuropathic pain
|
EP3194430A1
(de)
|
2014-09-16 |
2017-07-26 |
Universitat Autònoma De Barcelona |
Adeno-assoziierte virusvektoren zur gentheraüie von stoffwechselkrankheiten
|
US10370432B2
(en)
|
2014-10-03 |
2019-08-06 |
University Of Massachusetts |
Heterologous targeting peptide grafted AAVS
|
US10711270B2
(en)
|
2014-10-03 |
2020-07-14 |
University Of Massachusetts |
High efficiency library-identified AAV vectors
|
EP3209311B1
(de)
*
|
2014-10-21 |
2024-03-06 |
University of Massachusetts |
Rekombinante aav-varianten und verwendungen davon
|
MX2017005834A
(es)
|
2014-11-05 |
2017-11-17 |
Voyager Therapeutics Inc |
Polinucleotidos aad para el tratamiento de la enfermedad de parkinson.
|
RU2749882C2
(ru)
|
2014-11-14 |
2021-06-18 |
Вояджер Терапьютикс, Инк. |
Модулирующие полинуклеотиды
|
EP3218484A4
(de)
|
2014-11-14 |
2018-05-30 |
Voyager Therapeutics, Inc. |
Zusammensetzungen und verfahren zur behandlung von amyotropher lateralsklerose (als)
|
RU2727015C2
(ru)
|
2014-11-21 |
2020-07-17 |
Дзе Юниверсити Оф Норт Каролина Эт Чепел Хилл |
Векторы aav, нацеленные на центральную нервную систему
|
US11697825B2
(en)
|
2014-12-12 |
2023-07-11 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scAAV
|
ES2900973T3
(es)
|
2015-01-07 |
2022-03-21 |
UNIV AUTòNOMA DE BARCELONA |
Constructo genético de vector individual que comprende genes de insulina y glucoquinasa
|
WO2016115382A1
(en)
|
2015-01-14 |
2016-07-21 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeted gene transfer
|
KR102554850B1
(ko)
|
2015-02-06 |
2023-07-13 |
더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 |
최적화된 인간 응고 인자 viii 유전자 발현 카세트 및 그의 용도
|
EP3256170B1
(de)
|
2015-02-13 |
2020-09-23 |
University of Massachusetts |
Zusammensetzungen und verfahren zur transitorischen freisetzung von polypeptiden
|
US10968536B2
(en)
|
2015-02-25 |
2021-04-06 |
Jumpcode Genomics, Inc. |
Methods and compositions for sequencing
|
US10081659B2
(en)
|
2015-04-06 |
2018-09-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Adeno-associated vectors for enhanced transduction and reduced immunogenicity
|
CA3021949C
(en)
|
2015-04-24 |
2023-10-17 |
University Of Massachusetts |
Modified aav constructs and uses thereof
|
WO2017027866A1
(en)
*
|
2015-08-13 |
2017-02-16 |
University Of Florida Research Foundation, Inc. |
Aav6 vectors for immunotherapy
|
WO2017058892A2
(en)
|
2015-09-28 |
2017-04-06 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for antibody-evading virus vectors
|
WO2017059122A1
(en)
|
2015-09-29 |
2017-04-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human |
Methods of treating and preventing amyotrophic lateral sclerosis
|
CA3002980A1
(en)
|
2015-10-22 |
2017-04-27 |
University Of Massachusetts |
Prostate-targeting adeno-associated virus serotype vectors
|
US11253576B2
(en)
|
2015-10-22 |
2022-02-22 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance in neurodegenerative disease
|
RU2021102893A
(ru)
|
2015-11-05 |
2021-03-03 |
Бамбу Терапьютикс, Инк. |
Модифицированные гены атаксии фридрейха и векторы для генной терапии
|
CA3006569A1
(en)
|
2015-12-02 |
2017-06-08 |
Voyager Therapeutics, Inc. |
Assays for the detection of aav neutralizing antibodies
|
BR112018011881A2
(pt)
|
2015-12-14 |
2018-12-04 |
The University Of North Carolina At Chapel Hill |
proteínas capsidiais modificadas para liberação aumentada de vetores de parvovírus
|
IL260655B2
(en)
|
2016-01-29 |
2023-03-01 |
Sirion Biotech Gmbh |
AAV-based conditional expression system
|
CA3011939A1
(en)
|
2016-02-02 |
2017-08-10 |
University Of Massachusetts |
Method to enhance the efficiency of systemic aav gene delivery to the central nervous system
|
FI3411484T3
(fi)
|
2016-02-05 |
2023-11-15 |
Univ Emory |
Yksisäikeisen tai itsekomplementaarisen adenoassosioidun viruksen 9 injektio serebrospinaaliseen fluidiin
|
WO2017139381A1
(en)
|
2016-02-08 |
2017-08-17 |
University Of Iowa Research Foundation |
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
|
US11339427B2
(en)
|
2016-02-12 |
2022-05-24 |
Jumpcode Genomics, Inc. |
Method for target specific RNA transcription of DNA sequences
|
US11060088B2
(en)
|
2016-02-12 |
2021-07-13 |
University Of Massachusetts |
Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization
|
CN108697774A
(zh)
|
2016-02-22 |
2018-10-23 |
北卡罗来纳大学教堂山分校 |
治疗mps i-相关失明的aav-idua载体
|
AU2017229347A1
(en)
|
2016-03-07 |
2018-11-01 |
University Of Iowa Research Foundation |
AAV-mediated expression using a synthetic promoter and enhancer
|
EP3440210A4
(de)
|
2016-04-05 |
2019-11-27 |
University of Massachusetts |
Zusammensetzungen und verfahren zur selektiven hemmung der expression des grainyhead-like-proteins
|
US11413356B2
(en)
|
2016-04-15 |
2022-08-16 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance
|
EP3449250B1
(de)
|
2016-04-28 |
2020-11-04 |
Indiana University Research & Technology Corporation |
Verfahren und zusammensetzungen zur auflösung von komponenten einer viruspräparation
|
EP4049683A1
(de)
|
2016-04-29 |
2022-08-31 |
Adverum Biotechnologies, Inc. |
Evasion von neutralisierenden antikörpern durch ein rekombinantes adeno-assoziiertes virus
|
US11299751B2
(en)
|
2016-04-29 |
2022-04-12 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
EP3448874A4
(de)
|
2016-04-29 |
2020-04-22 |
Voyager Therapeutics, Inc. |
Zusammensetzungen zur behandlung einer erkrankung
|
FI3445773T3
(fi)
|
2016-05-13 |
2023-03-30 |
4D Molecular Therapeutics Inc |
Adenoassosioituneen viruksen kapsidimuunnoksia ja niiden käyttömenetelmiä
|
JP7220080B2
(ja)
|
2016-05-18 |
2023-02-09 |
ボイジャー セラピューティクス インコーポレイテッド |
ハンチントン病治療組成物及び方法
|
RU2758488C2
(ru)
|
2016-05-18 |
2021-10-28 |
Вояджер Терапьютикс, Инк. |
Модулирующие полинуклеотиды
|
JP2019517274A
(ja)
|
2016-06-13 |
2019-06-24 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill |
最適化されたcln1遺伝子および発現カセットおよびそれらの使用
|
US11882815B2
(en)
|
2016-06-15 |
2024-01-30 |
University Of Massachusetts |
Recombinant adeno-associated viruses for delivering gene editing molecules to embryonic cells
|
CA2971303A1
(en)
|
2016-06-21 |
2017-12-21 |
Bamboo Therapeutics, Inc. |
Optimized mini-dystrophin genes and expression cassettes and their use
|
JP2019521688A
(ja)
|
2016-07-26 |
2019-08-08 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
眼におけるベクター介在の免疫寛容
|
EP3506817A4
(de)
|
2016-08-30 |
2020-07-22 |
The Regents of The University of California |
Verfahren für biomedizinisches targeting und freisetzung sowie vorrichtungen und systeme zur ausführung davon
|
US10457940B2
(en)
|
2016-09-22 |
2019-10-29 |
University Of Massachusetts |
AAV treatment of Huntington's disease
|
AU2017341849B2
(en)
|
2016-10-13 |
2024-03-21 |
University Of Massachusetts |
AAV capsid designs
|
EP3528785A4
(de)
|
2016-10-19 |
2020-12-02 |
Adverum Biotechnologies, Inc. |
Modifizierte aav-kaspide und verwendungen davon
|
WO2018083606A1
(en)
|
2016-11-01 |
2018-05-11 |
Novartis Ag |
Methods and compositions for enhancing gene editing
|
US11142775B2
(en)
|
2017-01-13 |
2021-10-12 |
University Of Iowa Research Foundation |
Bocaparvovirus small noncoding RNA and uses thereof
|
EP3570895A1
(de)
|
2017-01-17 |
2019-11-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren zur expression eines bestimmten polynukleotids in den zapfen-fotorezeptoren
|
JP7081767B2
(ja)
*
|
2017-01-30 |
2022-06-07 |
学校法人日本医科大学 |
アデノ随伴ウイルス(aav)キャプシドタンパク質の変異体
|
AU2018234695B2
(en)
|
2017-03-15 |
2024-10-03 |
The University Of North Carolina At Chapel Hill |
Polyploid adeno-associated virus vectors and methods of making and using the same
|
EP3388520A1
(de)
|
2017-04-11 |
2018-10-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren und pharmazeutische zusammensetzung zur reduzierung der expression von nkcc1 in einer darauf angewiesenen person
|
WO2018204803A1
(en)
|
2017-05-05 |
2018-11-08 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating huntington's disease
|
WO2018204786A1
(en)
|
2017-05-05 |
2018-11-08 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
US11859179B2
(en)
|
2017-05-09 |
2024-01-02 |
University Of Massachusetts |
Methods of treating amyotrophic lateral sclerosis (ALS)
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
JP7229989B2
(ja)
|
2017-07-17 |
2023-02-28 |
ボイジャー セラピューティクス インコーポレイテッド |
軌道アレイガイドシステム
|
CN110945018A
(zh)
|
2017-07-27 |
2020-03-31 |
诺华股份有限公司 |
抗脱落酶的trem2变体
|
EP3662060A2
(de)
|
2017-08-03 |
2020-06-10 |
Voyager Therapeutics, Inc. |
Zusammensetzungen und verfahren zur aav-freisetzung
|
JP2020533968A
(ja)
*
|
2017-08-25 |
2020-11-26 |
オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics Inc. |
組換えアデノ随伴ベクター
|
RU2770922C2
(ru)
|
2017-09-20 |
2022-04-25 |
4Д Молекьюлар Терапьютикс Инк. |
Капсиды вариантов аденоассоциированных вирусов и методы их применения
|
US11668719B2
(en)
|
2017-09-20 |
2023-06-06 |
The Trustees Of Indiana University |
Methods for resolving lipoproteins with mass spectrometry
|
AU2018338188A1
(en)
|
2017-09-22 |
2020-04-02 |
University Of Massachusetts |
SOD1 dual expression vectors and uses thereof
|
EP4124658A3
(de)
|
2017-10-16 |
2023-04-19 |
Voyager Therapeutics, Inc. |
Behandlung von amyotropher lateralsklerose (als)
|
EP3697908A1
(de)
|
2017-10-16 |
2020-08-26 |
Voyager Therapeutics, Inc. |
Behandlung von amyotropher lateralsklerose (als)
|
WO2019077159A1
(en)
|
2017-10-20 |
2019-04-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS OF EXPRESSING POLYNUCLEOTIDE OF INTEREST IN CONE PHOTORECCEPTORS OF A SUBJECT COMPRISING SUB-RETINAL ADMINISTRATION OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF A RECOMBINANT AAV9 DERIVATIVE VECTOR
|
EP3707265A4
(de)
|
2017-11-07 |
2021-09-01 |
The University of North Carolina at Chapel Hill |
Optimierte aga-gene und expressionskassetten sowie deren verwendung
|
US11766489B2
(en)
|
2017-11-27 |
2023-09-26 |
4D Molecular Therapeutics, Inc. |
Adeno-associated virus variant capsids and use for inhibiting angiogenesis
|
WO2019140233A1
(en)
|
2018-01-12 |
2019-07-18 |
The Trustees Of Indiana University |
Electrostatic linear ion trap design for charge detection mass spectrometry
|
US20210277365A1
(en)
*
|
2018-01-17 |
2021-09-09 |
Adrenas Therapeutics, Inc. |
Adeno-associated virus gene therapy for 21-hydroxylase deficiency
|
KR20200123201A
(ko)
|
2018-02-21 |
2020-10-28 |
알시온 라이프사이언스 인크. |
유체 전달 시스템 및 방법
|
MX2020010466A
(es)
|
2018-04-03 |
2021-01-08 |
|
Vectores de virus que evitan anticuerpos.
|
EP3773743A1
(de)
|
2018-04-03 |
2021-02-17 |
Stridebio, Inc. |
Virusvektoren gegen ophthalmisches gewebe
|
BR112020020266A2
(pt)
|
2018-04-03 |
2021-01-19 |
Stridebio, Inc. |
Vetores de vírus com evasão de anticorpos
|
EP3790980A4
(de)
|
2018-05-06 |
2022-03-23 |
Emendobio Inc. |
Differentielles knockout eines allels eines heterozygoten elan-gens
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
CN112673452B
(zh)
|
2018-06-04 |
2024-08-23 |
印地安纳大学理事会 |
用于在静电线性离子阱中捕获离子的设备和方法
|
AU2019281714B2
(en)
|
2018-06-04 |
2024-05-02 |
The Trustees Of Indiana University |
Charge detection mass spectrometry with real time analysis and signal optimization
|
WO2019236139A1
(en)
|
2018-06-04 |
2019-12-12 |
The Trustees Of Indiana University |
Interface for transporting ions from an atmospheric pressure environment to a low pressure environment
|
EP4391015A3
(de)
|
2018-06-04 |
2024-10-09 |
The Trustees of Indiana University |
Ionenfallenanordnung für hochdurchsatz-ladungserkennungsmassenspektrometrie
|
WO2019236143A1
(en)
|
2018-06-04 |
2019-12-12 |
The Trustees Of Indiana University |
Apparatus and method for calibrating or resetting a charge detector
|
US20210246467A1
(en)
|
2018-06-12 |
2021-08-12 |
The University Of North Carolina At Chapel Hill |
Synthetic liver-tropic adeno-associated virus capsids and uses thereof
|
EP3807404A1
(de)
|
2018-06-13 |
2021-04-21 |
Voyager Therapeutics, Inc. |
Manipulierte 5'-unübersetzte regionen (5' utr) zur herstellung von aav
|
IL313246A
(en)
|
2018-06-28 |
2024-08-01 |
Univ North Carolina Chapel Hill |
CLN5 optimized genes and expression cassettes and their use
|
US20210355454A1
(en)
|
2018-07-24 |
2021-11-18 |
Voyager Therapeutics, Inc. |
Systems and methods for producing gene therapy formulations
|
EP3833767A4
(de)
|
2018-08-10 |
2022-05-04 |
The University of North Carolina at Chapel Hill |
Optimierte cln7-gene und expressionskassetten sowie deren verwendung
|
JP2021536289A
(ja)
|
2018-08-27 |
2021-12-27 |
アルキオーネ・ライフサイエンシズ・インコーポレイテッドAlcyone Lifesciences, Inc. |
流体送達システムおよび方法
|
WO2020069029A1
(en)
|
2018-09-26 |
2020-04-02 |
Emendobio Inc. |
Novel crispr nucleases
|
US20210348242A1
(en)
|
2018-10-04 |
2021-11-11 |
Voyager Therapeutics, Inc. |
Methods for measuring the titer and potency of viral vector particles
|
JP2022512621A
(ja)
|
2018-10-05 |
2022-02-07 |
ボイジャー セラピューティクス インコーポレイテッド |
Aav産生タンパク質をコードする操作された核酸コンストラクト
|
CA3116701A1
(en)
|
2018-10-15 |
2020-04-23 |
Voyager Therapeutics, Inc. |
Expression vectors for large-scale production of raav in the baculovirus/sf9 system
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
CN113574632B
(zh)
|
2018-11-20 |
2024-07-30 |
印地安纳大学理事会 |
用于单粒子质谱分析的轨道阱
|
CA3118567A1
(en)
|
2018-12-03 |
2020-06-11 |
The Trustees Of Indiana University |
Apparatus and method for simultaneously analyzing multiple ions with an electrostatic linear ion trap
|
US20220098621A1
(en)
|
2019-02-05 |
2022-03-31 |
Emendobio Inc. |
Crispr compositions and methods for promoting gene editing of ribosomal protein s19 (rps19) gene
|
WO2020163307A1
(en)
|
2019-02-06 |
2020-08-13 |
Emendobio Inc. |
New engineered high fidelity cas9
|
WO2020174369A2
(en)
|
2019-02-25 |
2020-09-03 |
Novartis Ag |
Compositions and methods to treat bietti crystalline dystrophy
|
BR112021016501A2
(pt)
|
2019-02-25 |
2021-10-26 |
Novartis Ag |
Composições e métodos para tratar distrofia cristalina de bietti
|
KR20220011616A
(ko)
|
2019-03-21 |
2022-01-28 |
스트라이드바이오 인코포레이티드 |
재조합 아데노 관련 바이러스 벡터
|
SG11202110607WA
(en)
*
|
2019-04-01 |
2021-10-28 |
Tenaya Therapeutics Inc |
Adeno-associated virus with engineered capsid
|
EP3959741A1
(de)
|
2019-04-23 |
2022-03-02 |
The Trustees of Indiana University |
Identifizierung von probensubspezies basierend auf partikelladungsverhalten unter strukturveränderungen induzierenden probenbedingungen
|
CA3136872A1
(en)
|
2019-04-23 |
2020-10-29 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
New adeno-associated virus (aav) variants and uses thereof for gene therapy
|
TW202106700A
(zh)
|
2019-04-26 |
2021-02-16 |
美商聖加莫治療股份有限公司 |
Aav 工程化
|
TW202104592A
(zh)
*
|
2019-05-14 |
2021-02-01 |
美商拜奧馬林製藥公司 |
重複投予基因療法載體之方法
|
WO2020242984A1
(en)
|
2019-05-24 |
2020-12-03 |
Regeneron Pharmaceuticals, Inc. |
Modified viral particles and uses thereof
|
WO2020261178A1
(en)
|
2019-06-27 |
2020-12-30 |
Pfizer Inc. |
Methods of treating duchenne muscular dystrophy using aav mini-dystrophin gene therapy
|
US10801042B1
(en)
|
2019-07-15 |
2020-10-13 |
Vigene Biosciences, Inc. |
Use of ion concentrations to increase the packaging efficiency of recombinant adeno-associated virus
|
US10557149B1
(en)
|
2019-07-15 |
2020-02-11 |
Vigene Biosciences, Inc. |
Recombinantly-modified adeno-associated virus helper vectors and their use to improve the packaging efficiency of recombinantly-modified adeno-associated virus
|
US10653731B1
(en)
|
2019-07-15 |
2020-05-19 |
Vigene Biosciences Inc. |
Recombinantly-modified adeno-associated virus (rAAV) having improved packaging efficiency
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
EP4031578A1
(de)
|
2019-09-18 |
2022-07-27 |
Novartis AG |
Entpd2-antikörper, kombinationstherapien und verfahren zur verwendung der antikörper und kombinationstherapien
|
AU2020356396A1
(en)
|
2019-09-25 |
2022-04-14 |
The Trustees Of Indiana University |
Apparatus and method for pulsed mode charge detection mass spectrometry
|
GB201913974D0
(en)
|
2019-09-27 |
2019-11-13 |
King S College London |
Vector
|
AU2020367532A1
(en)
|
2019-10-17 |
2022-05-12 |
Ginkgo Bioworks, Inc. |
Adeno-associated viral vectors for treatment of Niemann-Pick disease type C
|
WO2021170784A1
(en)
|
2020-02-28 |
2021-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Gene therapy for maple syrup urine disease
|
EP4121168A1
(de)
|
2020-03-20 |
2023-01-25 |
University of Florida Research Foundation, Inc. |
Gentherapie für das schabyne-syndrom
|
EP4100532A4
(de)
|
2020-03-23 |
2024-03-27 |
The University of North Carolina at Chapel Hill |
Aav-naglu-vektoren zur behandlung von mukopolysaccharidose iiib
|
WO2021207636A2
(en)
|
2020-04-10 |
2021-10-14 |
Sola Biosciences Llc |
Compositions and methods for the treatment of protein aggregation disorders
|
EP4143215A2
(de)
|
2020-04-28 |
2023-03-08 |
SOLA Biosciences LLC |
Zusammensetzungen und verfahren zur behandlung von tdp-43-proteinopathien
|
WO2021247995A2
(en)
|
2020-06-04 |
2021-12-09 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating neuropathic pain
|
JP2023529371A
(ja)
|
2020-06-05 |
2023-07-10 |
ソラ・バイオサイエンシズ・エルエルシー |
シヌクレイノパチーの処置のための組成物および方法
|
KR20230068444A
(ko)
|
2020-08-19 |
2023-05-17 |
사렙타 쎄러퓨틱스 인코퍼레이티드 |
레트 증후군의 치료를 위한 아데노 관련 바이러스 벡터
|
MX2023005218A
(es)
|
2020-11-03 |
2023-05-16 |
Pfizer |
Metodos de purificacion de vectores de aav mediante cromatografia de intercambio anionico.
|
US20240052322A1
(en)
|
2020-12-15 |
2024-02-15 |
Pfizer Inc. |
HILIC UPLC-MS Method For Separating and Analyzing Intact Adeno-Associated Virus Capsid Proteins
|
AU2021404944A1
(en)
|
2020-12-23 |
2023-07-06 |
Pfizer Inc. |
Methods for purification of aav vectors by affinity chromatography
|
TW202242124A
(zh)
|
2021-01-14 |
2022-11-01 |
美商史崔德生物公司 |
靶向t細胞之aav載體
|
US20240307553A1
(en)
|
2021-04-01 |
2024-09-19 |
Pfizer Inc. |
Pharmaceutical compositions containing adeno-associated viral vector
|
CA3216491A1
(en)
|
2021-04-16 |
2022-10-20 |
Asklepios Biopharmaceutical, Inc. |
Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response
|
EP4329820A1
(de)
|
2021-04-26 |
2024-03-06 |
Alexion Pharma International Operations Limited |
Adeno-assoziierte virale vektorkapside mit verbessertem gewebetropismus
|
KR20240014477A
(ko)
|
2021-05-28 |
2024-02-01 |
상하이 레제네리드 테라피즈 컴퍼니 리미티드 |
변이체 캡시드를 갖는 재조합 아데노-연관 바이러스 및 이의 응용
|
US20220396798A1
(en)
*
|
2021-06-12 |
2022-12-15 |
Shi-Lung Lin |
Novel mrna composition and production method for use in anti-viral and anti-cancer vaccines
|
EP4359547A1
(de)
|
2021-06-22 |
2024-05-01 |
Pfizer Inc. |
Herstellung eines adeno-assoziierten virusvektors in insektenzellen
|
JP2024523707A
(ja)
|
2021-07-08 |
2024-06-28 |
テナヤ セラピューティクス, インコーポレイテッド |
遺伝子治療のための最適化された発現カセット
|
JP2024530050A
(ja)
|
2021-08-11 |
2024-08-14 |
キングス・カレッジ・ロンドン |
中枢神経系に影響を及ぼす障害の改善された治療のための組成物及び方法
|
JP2024537178A
(ja)
|
2021-10-08 |
2024-10-10 |
ソラ・バイオサイエンシズ・エルエルシー |
p53媒介性癌の処置のための組成物および方法
|
EP4413024A2
(de)
|
2021-10-08 |
2024-08-14 |
SOLA Biosciences LLC |
Zusammensetzungen und verfahren zur behandlung von proteopathien
|
EP4419119A1
(de)
|
2021-10-20 |
2024-08-28 |
University of Rochester |
Isolierte glialvorläuferzellen zur verwendung bei der kompetitiven behandlung von altersbedingtem weissstoffverlust
|
US20230270818A1
(en)
|
2021-11-02 |
2023-08-31 |
University Of Rochester |
Tcf7l2 mediated remyelination in the brain
|
CA3233698A1
(en)
|
2021-11-04 |
2023-05-11 |
Regeneron Pharmaceuticals, Inc. |
Viral particles retargeted to skeletal muscle
|
WO2023114816A1
(en)
|
2021-12-14 |
2023-06-22 |
Neurogene, Inc. |
Recombinant optimized galc constructs and methods for treating galc-associated disorders
|
GB202201242D0
(en)
|
2022-01-31 |
2022-03-16 |
Univ Edinburgh |
Recombinant optimized mecp2 cassettes and methods for treating rett syndrome and related disorders
|
WO2023150687A1
(en)
|
2022-02-04 |
2023-08-10 |
Ginkgo Bioworks, Inc. |
Recombinant adeno-associated virus vectors, and methods of use thereof
|
TW202404993A
(zh)
|
2022-04-11 |
2024-02-01 |
美商特納亞治療股份有限公司 |
具經工程化蛋白殼之腺相關病毒
|
GB202206336D0
(en)
|
2022-04-29 |
2022-06-15 |
Univ Edinburgh |
Recombinant therapeutic FMR1 constructs and methods of treating fragile X syndrome and related disorders
|
WO2023214346A1
(en)
|
2022-05-06 |
2023-11-09 |
Novartis Ag |
Novel recombinant aav vp2 fusion polypeptides
|
WO2023220603A1
(en)
|
2022-05-09 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
Vectors and methods for in vivo antibody production
|
WO2024003687A1
(en)
|
2022-06-28 |
2024-01-04 |
Pfizer Inc. |
Nucleic acids encoding acid alpha-glucosidase (gaa) and vectors for gene therapy
|
WO2024026494A1
(en)
|
2022-07-29 |
2024-02-01 |
Regeneron Pharmaceuticals, Inc. |
Viral particles retargeted to transferrin receptor 1
|
WO2024038365A1
(en)
|
2022-08-16 |
2024-02-22 |
Pfizer Inc. |
Methods for purification of aav vectors by anion exchange chromatography
|
WO2024107765A2
(en)
|
2022-11-14 |
2024-05-23 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes
|
WO2024124019A2
(en)
|
2022-12-07 |
2024-06-13 |
Ginkgo Bioworks, Inc. |
Aav vectors targeting hematopoietic stem cells
|
WO2024130175A2
(en)
|
2022-12-16 |
2024-06-20 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind to aav particles and uses
|
WO2024147114A1
(en)
|
2023-01-06 |
2024-07-11 |
Bloomsbury Genetic Therapies Limited |
Compositions and methods for treating parkinson's disease
|
WO2024163747A2
(en)
|
2023-02-02 |
2024-08-08 |
University Of Rochester |
Competitive replacement of glial cells
|
WO2024173248A1
(en)
|
2023-02-13 |
2024-08-22 |
Regeneron Pharmaceuticals, Inc. |
Treatment of muscle related disorders with anti-human cacng1 antibodies
|