US6924128B2
(en)
|
1994-12-06 |
2005-08-02 |
Targeted Genetics Corporation |
Packaging cell lines for generation of high titers of recombinant AAV vectors
|
AU4645697A
(en)
|
1996-09-11 |
1998-04-02 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Aav4 vector and uses thereof
|
US6989264B2
(en)
|
1997-09-05 |
2006-01-24 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
ATE402254T1
(de)
|
1998-05-28 |
2008-08-15 |
Us Gov Health & Human Serv |
Aav5 vektoren und deren verwendung
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
ES2340230T3
(es)
|
1998-11-10 |
2010-05-31 |
University Of North Carolina At Chapel Hill |
Vectores viricos y sus procedimientos de preparacion y administracion.
|
US6627617B1
(en)
|
1999-10-01 |
2003-09-30 |
University Of North Carolina At Chapel Hill |
Temperature-sensitive regulation of viral vector production
|
DE10120265A1
(de)
*
|
2001-04-25 |
2002-11-14 |
Deutsches Krebsforsch |
AAV-Helferplasmide zur Helfervirus-freien Verpackung und Pseudotypisierung von AAV-Vektoren
|
NZ578982A
(en)
|
2001-11-13 |
2011-03-31 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
|
AU2008202344B2
(en)
*
|
2001-11-13 |
2011-08-25 |
The Trustees Of The University Of Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
|
CN112029800A
(zh)
*
|
2001-11-13 |
2020-12-04 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
JP4769417B2
(ja)
*
|
2001-12-17 |
2011-09-07 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
アデノ随伴ウイルス(aav)血清型9の配列、それを含むベクターおよびその使用
|
ES2975413T3
(es)
|
2001-12-17 |
2024-07-05 |
Univ Pennsylvania |
Secuencias de serotipo 8 de virus adenoasociado (AAV), vectores que las contienen y usos de las mismas
|
MXPA04008890A
(es)
|
2002-03-15 |
2005-10-18 |
Wyeth Corp |
Mutantes de la proteina p4 de haemophilus influenzae no tipicable con actividad enzimatica reducida.
|
US7419817B2
(en)
|
2002-05-17 |
2008-09-02 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
|
US8927269B2
(en)
|
2003-05-19 |
2015-01-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Avian adenoassociated virus and uses thereof
|
ES2648241T3
(es)
|
2003-09-30 |
2017-12-29 |
The Trustees Of The University Of Pennsylvania |
Clados de virus adenoasociados (AAV), secuencias, vectores que contienen el mismo, y usos de los mismos
|
US8137960B2
(en)
|
2003-12-04 |
2012-03-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Bovine adeno-associated viral (BAAV) vector and uses thereof
|
WO2006078279A2
(en)
|
2004-04-28 |
2006-07-27 |
The Trustees Of The University Of Pennsylvania |
Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations
|
EP1742657B1
(en)
|
2004-04-28 |
2013-11-06 |
The Trustees of The University of Pennsylvania |
Immunization regimen with e4-deleted adenovirus prime and e1-deleted adenovirus boost
|
NZ555830A
(en)
|
2004-12-15 |
2009-01-31 |
Univ North Carolina |
Chimeric vectors
|
US8999678B2
(en)
|
2005-04-07 |
2015-04-07 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an AAV vector
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
WO2008016391A2
(en)
*
|
2006-01-31 |
2008-02-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
US9198984B2
(en)
|
2006-04-28 |
2015-12-01 |
The Trustees Of The University Of Pennsylvania |
Scalable production method for AAV
|
US8221738B2
(en)
|
2008-02-19 |
2012-07-17 |
Celladon Corporation |
Method for enhanced uptake of viral vectors in the myocardium
|
EP2396343B1
(en)
|
2009-02-11 |
2017-05-17 |
The University of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
CN102448501A
(zh)
|
2009-03-27 |
2012-05-09 |
西马生物医学计划公司 |
治疗肝硬化和肝纤维化的方法和组合物
|
BR112012010755A2
(pt)
|
2009-11-05 |
2015-09-22 |
Proyecto Biomedicina Cima Sl |
constructo de gene que permite a expressão hepato-específica induzível de um polinucleotídeo de interesse em resposta a um agente indutor, vetor, genoma viral recombinante, vírion, método in vitro para a expressão de um polinucleotídeo de interesse em uma célula de origem hepática, composição farmacêutica e operador-promotor bi-direcional induzível adequado para a expressão hepato-específica induzível de dois polinucleotídeos de interesse por um agente indutor
|
EP2524037B1
(en)
|
2010-01-12 |
2018-05-16 |
The University Of North Carolina At Chapel Hill |
Restrictive inverted terminal repeats for viral vectors
|
US9309534B2
(en)
|
2010-07-12 |
2016-04-12 |
Universidad Autonoma De Barcelona |
Gene therapy composition for use in diabetes treatment
|
JP5704361B2
(ja)
*
|
2010-10-27 |
2015-04-22 |
学校法人自治医科大学 |
神経系細胞への遺伝子導入のためのアデノ随伴ウイルスビリオン
|
EP4234571A3
(en)
|
2011-02-10 |
2023-09-27 |
The University of North Carolina at Chapel Hill |
Viral vectors with modified transduction profiles and methods of making and using the same
|
RS62795B1
(sr)
|
2011-04-22 |
2022-02-28 |
Univ California |
Adeno-povezani virioni virusa sa varijantama kapsida i postupci za njihovu primenu
|
EP2692868A1
(en)
|
2012-08-02 |
2014-02-05 |
Universitat Autònoma De Barcelona |
Adeno-associated viral (AAV) vectors useful for transducing adipose tissue
|
PL2900686T3
(pl)
|
2012-09-28 |
2021-01-25 |
The University Of North Carolina At Chapel Hill |
Wektory aav ukierunkowane na oligodendrocyty
|
AU2014227766B2
(en)
|
2013-03-15 |
2018-10-04 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding AAV vectors
|
WO2014143932A1
(en)
|
2013-03-15 |
2014-09-18 |
The University Of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
EP3008191A2
(en)
|
2013-06-13 |
2016-04-20 |
Shire Human Genetic Therapies, Inc. |
Messenger rna based viral production
|
EP4039813A1
(en)
*
|
2013-07-12 |
2022-08-10 |
The Children's Hospital of Philadelphia |
Aav vector and assay for anti-aav (adeno-associated virus) neutralizing antibodies
|
US20160354489A1
(en)
|
2013-09-26 |
2016-12-08 |
Universitat Autònome de Barcelona |
Gene therapy compositions for use in the prevention and/or treatment of non-alcoholic fatty liver disease
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
PL3116900T3
(pl)
|
2014-03-09 |
2021-03-08 |
The Trustees Of The University Of Pennsylvania |
Kompozycje użyteczne w leczeniu niedoboru transkarbamylazy ornitynowej (otc)
|
US9458464B2
(en)
|
2014-06-23 |
2016-10-04 |
The Johns Hopkins University |
Treatment of neuropathic pain
|
EP3194430A1
(en)
|
2014-09-16 |
2017-07-26 |
Universitat Autònoma De Barcelona |
Adeno-associated viral vectors for the gene therapy of metabolic diseases
|
RU2727015C2
(ru)
|
2014-11-21 |
2020-07-17 |
Дзе Юниверсити Оф Норт Каролина Эт Чепел Хилл |
Векторы aav, нацеленные на центральную нервную систему
|
ES2900973T3
(es)
|
2015-01-07 |
2022-03-21 |
UNIV AUTòNOMA DE BARCELONA |
Constructo genético de vector individual que comprende genes de insulina y glucoquinasa
|
WO2016115382A1
(en)
|
2015-01-14 |
2016-07-21 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeted gene transfer
|
KR102554850B1
(ko)
|
2015-02-06 |
2023-07-13 |
더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 |
최적화된 인간 응고 인자 viii 유전자 발현 카세트 및 그의 용도
|
WO2017058892A2
(en)
|
2015-09-28 |
2017-04-06 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for antibody-evading virus vectors
|
RU2021102893A
(ru)
|
2015-11-05 |
2021-03-03 |
Бамбу Терапьютикс, Инк. |
Модифицированные гены атаксии фридрейха и векторы для генной терапии
|
ES2934848T3
(es)
|
2015-12-11 |
2023-02-27 |
Univ Pennsylvania |
Método de purificación escalable para AAV8
|
WO2017100704A1
(en)
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aavrh10
|
US11015173B2
(en)
|
2015-12-11 |
2021-05-25 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for AAV1
|
US11098286B2
(en)
|
2015-12-11 |
2021-08-24 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for AAV9
|
BR112018011881A2
(pt)
|
2015-12-14 |
2018-12-04 |
The University Of North Carolina At Chapel Hill |
proteínas capsidiais modificadas para liberação aumentada de vetores de parvovírus
|
FI3411484T3
(fi)
|
2016-02-05 |
2023-11-15 |
Univ Emory |
Yksisäikeisen tai itsekomplementaarisen adenoassosioidun viruksen 9 injektio serebrospinaaliseen fluidiin
|
CN108697774A
(zh)
|
2016-02-22 |
2018-10-23 |
北卡罗来纳大学教堂山分校 |
治疗mps i-相关失明的aav-idua载体
|
EP3449250B1
(en)
|
2016-04-28 |
2020-11-04 |
Indiana University Research & Technology Corporation |
Methods and compositions for resolving components of a virus preparation
|
EP3448874A4
(en)
*
|
2016-04-29 |
2020-04-22 |
Voyager Therapeutics, Inc. |
COMPOSITIONS FOR TREATING A DISEASE
|
EP3448875A4
(en)
*
|
2016-04-29 |
2020-04-08 |
Voyager Therapeutics, Inc. |
COMPOSITIONS FOR TREATING A DISEASE
|
EP4049683A1
(en)
|
2016-04-29 |
2022-08-31 |
Adverum Biotechnologies, Inc. |
Evasion of neutralizing antibodies by a recombinant adeno-associated virus
|
US11299751B2
(en)
|
2016-04-29 |
2022-04-12 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
WO2017192750A1
(en)
*
|
2016-05-04 |
2017-11-09 |
Oregon Health & Science University |
Recombinant adeno-associated viral vectors
|
FI3445773T3
(fi)
|
2016-05-13 |
2023-03-30 |
4D Molecular Therapeutics Inc |
Adenoassosioituneen viruksen kapsidimuunnoksia ja niiden käyttömenetelmiä
|
JP2019517274A
(ja)
|
2016-06-13 |
2019-06-24 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill |
最適化されたcln1遺伝子および発現カセットおよびそれらの使用
|
CA2971303A1
(en)
|
2016-06-21 |
2017-12-21 |
Bamboo Therapeutics, Inc. |
Optimized mini-dystrophin genes and expression cassettes and their use
|
JP2019521688A
(ja)
|
2016-07-26 |
2019-08-08 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
眼におけるベクター介在の免疫寛容
|
EP3528785A4
(en)
|
2016-10-19 |
2020-12-02 |
Adverum Biotechnologies, Inc. |
MODIFIED AAV CASPIDS AND USES THEREOF
|
WO2018083606A1
(en)
|
2016-11-01 |
2018-05-11 |
Novartis Ag |
Methods and compositions for enhancing gene editing
|
EP3570895A1
(en)
|
2017-01-17 |
2019-11-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of expressing a polynucleotide of interest in the cone photoreceptors
|
US20210130413A1
(en)
*
|
2017-02-28 |
2021-05-06 |
Adverum Biotechnologies, Inc. |
Modified aav capsids and uses thereof
|
AU2018234695B2
(en)
|
2017-03-15 |
2024-10-03 |
The University Of North Carolina At Chapel Hill |
Polyploid adeno-associated virus vectors and methods of making and using the same
|
EP3388520A1
(en)
|
2017-04-11 |
2018-10-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for reducing the expression of nkcc1 in a subject in need thereof
|
CN110945018A
(zh)
|
2017-07-27 |
2020-03-31 |
诺华股份有限公司 |
抗脱落酶的trem2变体
|
RU2770922C2
(ru)
|
2017-09-20 |
2022-04-25 |
4Д Молекьюлар Терапьютикс Инк. |
Капсиды вариантов аденоассоциированных вирусов и методы их применения
|
US11668719B2
(en)
|
2017-09-20 |
2023-06-06 |
The Trustees Of Indiana University |
Methods for resolving lipoproteins with mass spectrometry
|
WO2019077159A1
(en)
|
2017-10-20 |
2019-04-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS OF EXPRESSING POLYNUCLEOTIDE OF INTEREST IN CONE PHOTORECCEPTORS OF A SUBJECT COMPRISING SUB-RETINAL ADMINISTRATION OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF A RECOMBINANT AAV9 DERIVATIVE VECTOR
|
EP3707265A4
(en)
|
2017-11-07 |
2021-09-01 |
The University of North Carolina at Chapel Hill |
OPTIMIZED AGA GENES AND OPTIMIZED EXPRESSION CASSETTES AND THEIR USE
|
US11766489B2
(en)
|
2017-11-27 |
2023-09-26 |
4D Molecular Therapeutics, Inc. |
Adeno-associated virus variant capsids and use for inhibiting angiogenesis
|
WO2019140233A1
(en)
|
2018-01-12 |
2019-07-18 |
The Trustees Of Indiana University |
Electrostatic linear ion trap design for charge detection mass spectrometry
|
KR20200123201A
(ko)
|
2018-02-21 |
2020-10-28 |
알시온 라이프사이언스 인크. |
유체 전달 시스템 및 방법
|
MX2020010466A
(es)
|
2018-04-03 |
2021-01-08 |
|
Vectores de virus que evitan anticuerpos.
|
EP3773743A1
(en)
|
2018-04-03 |
2021-02-17 |
Stridebio, Inc. |
Virus vectors for targeting ophthalmic tissues
|
BR112020020266A2
(pt)
|
2018-04-03 |
2021-01-19 |
Stridebio, Inc. |
Vetores de vírus com evasão de anticorpos
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
AU2019281714B2
(en)
|
2018-06-04 |
2024-05-02 |
The Trustees Of Indiana University |
Charge detection mass spectrometry with real time analysis and signal optimization
|
WO2019236143A1
(en)
|
2018-06-04 |
2019-12-12 |
The Trustees Of Indiana University |
Apparatus and method for calibrating or resetting a charge detector
|
EP4391015A3
(en)
|
2018-06-04 |
2024-10-09 |
The Trustees of Indiana University |
Ion trap array for high throughput charge detection mass spectrometry
|
WO2019236139A1
(en)
|
2018-06-04 |
2019-12-12 |
The Trustees Of Indiana University |
Interface for transporting ions from an atmospheric pressure environment to a low pressure environment
|
CN112673452B
(zh)
|
2018-06-04 |
2024-08-23 |
印地安纳大学理事会 |
用于在静电线性离子阱中捕获离子的设备和方法
|
US20210246467A1
(en)
|
2018-06-12 |
2021-08-12 |
The University Of North Carolina At Chapel Hill |
Synthetic liver-tropic adeno-associated virus capsids and uses thereof
|
EP3807404A1
(en)
|
2018-06-13 |
2021-04-21 |
Voyager Therapeutics, Inc. |
Engineered 5' untranslated regions (5' utr) for aav production
|
IL313246A
(en)
|
2018-06-28 |
2024-08-01 |
Univ North Carolina Chapel Hill |
CLN5 optimized genes and expression cassettes and their use
|
US20210355454A1
(en)
|
2018-07-24 |
2021-11-18 |
Voyager Therapeutics, Inc. |
Systems and methods for producing gene therapy formulations
|
EP3833767A4
(en)
|
2018-08-10 |
2022-05-04 |
The University of North Carolina at Chapel Hill |
OPTIMIZED CLN7 GENES AND EXPRESSION CASSETTES AND THEIR USE
|
JP2021536289A
(ja)
|
2018-08-27 |
2021-12-27 |
アルキオーネ・ライフサイエンシズ・インコーポレイテッドAlcyone Lifesciences, Inc. |
流体送達システムおよび方法
|
US20210348242A1
(en)
|
2018-10-04 |
2021-11-11 |
Voyager Therapeutics, Inc. |
Methods for measuring the titer and potency of viral vector particles
|
JP2022512621A
(ja)
|
2018-10-05 |
2022-02-07 |
ボイジャー セラピューティクス インコーポレイテッド |
Aav産生タンパク質をコードする操作された核酸コンストラクト
|
CA3116701A1
(en)
|
2018-10-15 |
2020-04-23 |
Voyager Therapeutics, Inc. |
Expression vectors for large-scale production of raav in the baculovirus/sf9 system
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
CN113574632B
(zh)
|
2018-11-20 |
2024-07-30 |
印地安纳大学理事会 |
用于单粒子质谱分析的轨道阱
|
CA3118567A1
(en)
|
2018-12-03 |
2020-06-11 |
The Trustees Of Indiana University |
Apparatus and method for simultaneously analyzing multiple ions with an electrostatic linear ion trap
|
BR112021016501A2
(pt)
|
2019-02-25 |
2021-10-26 |
Novartis Ag |
Composições e métodos para tratar distrofia cristalina de bietti
|
WO2020174369A2
(en)
|
2019-02-25 |
2020-09-03 |
Novartis Ag |
Compositions and methods to treat bietti crystalline dystrophy
|
KR20220011616A
(ko)
|
2019-03-21 |
2022-01-28 |
스트라이드바이오 인코포레이티드 |
재조합 아데노 관련 바이러스 벡터
|
SG11202110607WA
(en)
|
2019-04-01 |
2021-10-28 |
Tenaya Therapeutics Inc |
Adeno-associated virus with engineered capsid
|
CA3136872A1
(en)
|
2019-04-23 |
2020-10-29 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
New adeno-associated virus (aav) variants and uses thereof for gene therapy
|
EP3959741A1
(en)
|
2019-04-23 |
2022-03-02 |
The Trustees of Indiana University |
Identification of sample subspecies based on particle charge behavior under structural change-inducing sample conditions
|
JP2022529662A
(ja)
|
2019-04-26 |
2022-06-23 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
二重グリカン結合aav2.5ベクターのための方法および組成物
|
TW202106700A
(zh)
|
2019-04-26 |
2021-02-16 |
美商聖加莫治療股份有限公司 |
Aav 工程化
|
WO2020242984A1
(en)
|
2019-05-24 |
2020-12-03 |
Regeneron Pharmaceuticals, Inc. |
Modified viral particles and uses thereof
|
WO2020261178A1
(en)
|
2019-06-27 |
2020-12-30 |
Pfizer Inc. |
Methods of treating duchenne muscular dystrophy using aav mini-dystrophin gene therapy
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
EP4031578A1
(en)
|
2019-09-18 |
2022-07-27 |
Novartis AG |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
AU2020356396A1
(en)
|
2019-09-25 |
2022-04-14 |
The Trustees Of Indiana University |
Apparatus and method for pulsed mode charge detection mass spectrometry
|
GB201913974D0
(en)
|
2019-09-27 |
2019-11-13 |
King S College London |
Vector
|
AU2020367532A1
(en)
|
2019-10-17 |
2022-05-12 |
Ginkgo Bioworks, Inc. |
Adeno-associated viral vectors for treatment of Niemann-Pick disease type C
|
WO2021170784A1
(en)
|
2020-02-28 |
2021-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Gene therapy for maple syrup urine disease
|
EP4121168A1
(en)
|
2020-03-20 |
2023-01-25 |
University of Florida Research Foundation, Inc. |
Gene therapy for cockayne syndrome
|
EP4100532A4
(en)
|
2020-03-23 |
2024-03-27 |
The University of North Carolina at Chapel Hill |
AAV-NAGLU VECTORS FOR THE TREATMENT OF MUCOPOLYSACCHARIDOSIS IIIB
|
JP2023537070A
(ja)
|
2020-08-07 |
2023-08-30 |
アミカス セラピューティックス インコーポレイテッド |
小胞を標的とするタンパク質及びその使用
|
KR20230068444A
(ko)
|
2020-08-19 |
2023-05-17 |
사렙타 쎄러퓨틱스 인코퍼레이티드 |
레트 증후군의 치료를 위한 아데노 관련 바이러스 벡터
|
CA3196036A1
(en)
|
2020-10-28 |
2022-05-05 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding aav2.5 vector
|
WO2022093769A1
(en)
|
2020-10-28 |
2022-05-05 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding aav2.5 vector
|
MX2023005218A
(es)
|
2020-11-03 |
2023-05-16 |
Pfizer |
Metodos de purificacion de vectores de aav mediante cromatografia de intercambio anionico.
|
US20240052322A1
(en)
|
2020-12-15 |
2024-02-15 |
Pfizer Inc. |
HILIC UPLC-MS Method For Separating and Analyzing Intact Adeno-Associated Virus Capsid Proteins
|
AU2021404944A1
(en)
|
2020-12-23 |
2023-07-06 |
Pfizer Inc. |
Methods for purification of aav vectors by affinity chromatography
|
TW202242124A
(zh)
|
2021-01-14 |
2022-11-01 |
美商史崔德生物公司 |
靶向t細胞之aav載體
|
AU2022214429A1
(en)
|
2021-02-01 |
2023-09-14 |
Regenxbio Inc. |
Gene therapy for neuronal ceroid lipofuscinoses
|
US20240307553A1
(en)
|
2021-04-01 |
2024-09-19 |
Pfizer Inc. |
Pharmaceutical compositions containing adeno-associated viral vector
|
CA3216491A1
(en)
|
2021-04-16 |
2022-10-20 |
Asklepios Biopharmaceutical, Inc. |
Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response
|
EP4329820A1
(en)
|
2021-04-26 |
2024-03-06 |
Alexion Pharma International Operations Limited |
Adeno-associated viral vector capsids with improved tissue tropism
|
KR20240014477A
(ko)
|
2021-05-28 |
2024-02-01 |
상하이 레제네리드 테라피즈 컴퍼니 리미티드 |
변이체 캡시드를 갖는 재조합 아데노-연관 바이러스 및 이의 응용
|
EP4359547A1
(en)
|
2021-06-22 |
2024-05-01 |
Pfizer Inc. |
Production of adeno-associated virus vector in insect cells
|
US20240318157A1
(en)
|
2021-07-01 |
2024-09-26 |
Amicus Therapeutics, Inc. |
Neurotensin Variants And Tagged Proteins Comprising Neurotensin Or Sortilin Propeptide
|
JP2024523707A
(ja)
|
2021-07-08 |
2024-06-28 |
テナヤ セラピューティクス, インコーポレイテッド |
遺伝子治療のための最適化された発現カセット
|
JP2024530050A
(ja)
|
2021-08-11 |
2024-08-14 |
キングス・カレッジ・ロンドン |
中枢神経系に影響を及ぼす障害の改善された治療のための組成物及び方法
|
EP4419119A1
(en)
|
2021-10-20 |
2024-08-28 |
University of Rochester |
Isolated glial progenitor cells for use in the competition treatment of age-related white matter loss
|
US20230270818A1
(en)
|
2021-11-02 |
2023-08-31 |
University Of Rochester |
Tcf7l2 mediated remyelination in the brain
|
CA3233698A1
(en)
|
2021-11-04 |
2023-05-11 |
Regeneron Pharmaceuticals, Inc. |
Viral particles retargeted to skeletal muscle
|
WO2023114816A1
(en)
|
2021-12-14 |
2023-06-22 |
Neurogene, Inc. |
Recombinant optimized galc constructs and methods for treating galc-associated disorders
|
GB202201242D0
(en)
|
2022-01-31 |
2022-03-16 |
Univ Edinburgh |
Recombinant optimized mecp2 cassettes and methods for treating rett syndrome and related disorders
|
WO2023150687A1
(en)
|
2022-02-04 |
2023-08-10 |
Ginkgo Bioworks, Inc. |
Recombinant adeno-associated virus vectors, and methods of use thereof
|
TW202404993A
(zh)
|
2022-04-11 |
2024-02-01 |
美商特納亞治療股份有限公司 |
具經工程化蛋白殼之腺相關病毒
|
GB202206336D0
(en)
|
2022-04-29 |
2022-06-15 |
Univ Edinburgh |
Recombinant therapeutic FMR1 constructs and methods of treating fragile X syndrome and related disorders
|
WO2023214346A1
(en)
|
2022-05-06 |
2023-11-09 |
Novartis Ag |
Novel recombinant aav vp2 fusion polypeptides
|
WO2023220603A1
(en)
|
2022-05-09 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
Vectors and methods for in vivo antibody production
|
WO2024003687A1
(en)
|
2022-06-28 |
2024-01-04 |
Pfizer Inc. |
Nucleic acids encoding acid alpha-glucosidase (gaa) and vectors for gene therapy
|
WO2024026494A1
(en)
|
2022-07-29 |
2024-02-01 |
Regeneron Pharmaceuticals, Inc. |
Viral particles retargeted to transferrin receptor 1
|
WO2024038365A1
(en)
|
2022-08-16 |
2024-02-22 |
Pfizer Inc. |
Methods for purification of aav vectors by anion exchange chromatography
|
WO2024107765A2
(en)
|
2022-11-14 |
2024-05-23 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes
|
WO2024124019A2
(en)
|
2022-12-07 |
2024-06-13 |
Ginkgo Bioworks, Inc. |
Aav vectors targeting hematopoietic stem cells
|
WO2024130175A2
(en)
|
2022-12-16 |
2024-06-20 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind to aav particles and uses
|
WO2024147114A1
(en)
|
2023-01-06 |
2024-07-11 |
Bloomsbury Genetic Therapies Limited |
Compositions and methods for treating parkinson's disease
|
WO2024163747A2
(en)
|
2023-02-02 |
2024-08-08 |
University Of Rochester |
Competitive replacement of glial cells
|
WO2024173248A1
(en)
|
2023-02-13 |
2024-08-22 |
Regeneron Pharmaceuticals, Inc. |
Treatment of muscle related disorders with anti-human cacng1 antibodies
|