MX9708427A - Serpina derivada de pancreas. - Google Patents

Serpina derivada de pancreas.

Info

Publication number
MX9708427A
MX9708427A MX9708427A MX9708427A MX9708427A MX 9708427 A MX9708427 A MX 9708427A MX 9708427 A MX9708427 A MX 9708427A MX 9708427 A MX9708427 A MX 9708427A MX 9708427 A MX9708427 A MX 9708427A
Authority
MX
Mexico
Prior art keywords
pds
pancreas
encode
binding specifically
provides
Prior art date
Application number
MX9708427A
Other languages
English (en)
Other versions
MXPA97008427A (es
Inventor
Scott Michael Braxton
Craig G Wilde
Dinh Diep
Original Assignee
Incyte Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc filed Critical Incyte Pharma Inc
Publication of MXPA97008427A publication Critical patent/MXPA97008427A/es
Publication of MX9708427A publication Critical patent/MX9708427A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invencion provee secuencias de nucleotidos y aminoácidos que identifican y codifican Serpina Derivada de Páncreas (SDP) novedosa expresada en páncreas humano. La presente invencion también provee moléculas de contrasentido a las secuencias de nucleotidos que codifican SDP, vectores de expresion para la produccion de SDP purificadas, anticuerpos capaces de unirse específicamente a SDP, sondas de hibridizacion u oligonucleotidos para la deteccion de secuencias de nucleotidos que codifican SDP, células huésped tratada genéticamente para la expresion de sdp, pruebas de diagnostico basadas en moléculas de ácido nucleico que codifican SDP y una composicion farmacéutica que contiene SDP capaces de unirse específicamente a una proteasa de serina.
MX9708427A 1995-05-02 1996-05-01 Serpina derivada de pancreas. MX9708427A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/434,881 US5804376A (en) 1995-05-02 1995-05-02 Pancreas-derived serpin
US08434881 1995-05-02
PCT/US1996/006137 WO1996034957A1 (en) 1995-05-02 1996-05-01 Pancreas-derived serpin

Publications (2)

Publication Number Publication Date
MXPA97008427A MXPA97008427A (es) 1998-02-01
MX9708427A true MX9708427A (es) 1998-02-28

Family

ID=23726083

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9708427A MX9708427A (es) 1995-05-02 1996-05-01 Serpina derivada de pancreas.

Country Status (7)

Country Link
US (3) US5804376A (es)
EP (1) EP0826048A1 (es)
JP (1) JPH11505418A (es)
AU (1) AU722412B2 (es)
CA (1) CA2218034A1 (es)
MX (1) MX9708427A (es)
WO (1) WO1996034957A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US5804376A (en) * 1995-05-02 1998-09-08 Incyte Pharmaceuticals, Inc. Pancreas-derived serpin
US6303338B1 (en) 1996-08-16 2001-10-16 Human Genome Sciences, Inc. Pancreas-derived plasminogen activator inhibitor
US6896899B2 (en) * 1996-12-31 2005-05-24 Antioxidant Pharmaceuticals Corp. Pharmaceutical preparations of glutathione and methods of administration thereof
WO1998029101A1 (en) 1996-12-31 1998-07-09 Antioxidant Pharmaceuticals Corporation Pharmaceutical preparations of glutathione and methods of administration thereof
WO1999009161A1 (en) * 1997-08-15 1999-02-25 Human Genome Sciences, Inc. Pancreas-derived plasminogen activator inhibitor
WO1999011786A1 (fr) * 1997-09-01 1999-03-11 Otsuka Pharmaceutical Co., Ltd. GENE pancpin ET COMPOSITION DE THERAPIE GENIQUE
DE19742725A1 (de) * 1997-09-26 1999-04-01 Abts Harry Frank Dr Hurpin/PI13: Ein neuer, UV-reprimierbarer, Serin Protease Inhibitor aus der Familie der Ovalbumin-Serpine
NZ512244A (en) * 1998-11-12 2003-12-19 Invitrogen Corp Polycationic transfection reagents for introducing anions into a cell
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US20030215821A1 (en) * 1999-04-20 2003-11-20 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
AU2250401A (en) * 1999-11-29 2001-06-04 Zymogenetics Inc. Human serpin
US6524822B1 (en) 1999-11-29 2003-02-25 Zymogenetics, Inc. Polynucleotide encoding human serpin
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
CA2399733C (en) * 2000-02-07 2011-09-20 Illumina, Inc. Nucleic acid detection methods using universal priming
EP1316320A4 (en) * 2000-09-07 2005-12-07 Tokyo Gas Co Ltd PREPARATIONS FOR DIAGNOSING THE EXTRAPANCREATIC SECRETION FUNCTION
ATE477020T1 (de) 2002-06-07 2010-08-15 Dyax Corp Prevention und verringerung von ischemia
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
US7774145B2 (en) * 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
CA2536873C (en) * 2003-08-29 2019-09-10 Dyax Corp. Poly-pegylated protease inhibitors
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
WO2009026334A2 (en) * 2007-08-21 2009-02-26 Genzyme Corporation Treatment with kallikrein inhibitors
AU2010203712A1 (en) * 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
JP6037841B2 (ja) * 2010-01-06 2016-12-07 ダイアックス コーポレーション 血漿カリクレイン結合タンパク質
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
US10428158B2 (en) 2014-03-27 2019-10-01 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
CN106572974B (zh) 2014-07-15 2021-04-23 生命技术公司 用于将分子有效递送到细胞的具有脂质聚集体的组合物和方法
CN108602893A (zh) 2015-12-11 2018-09-28 戴埃克斯有限公司 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07508646A (ja) * 1992-06-04 1995-09-28 ユニバーシティ オブ サザン カリフォルニア 網膜の色素沈着された上皮由来の神経栄養性因子
US5804376A (en) * 1995-05-02 1998-09-08 Incyte Pharmaceuticals, Inc. Pancreas-derived serpin

Also Published As

Publication number Publication date
US6197519B1 (en) 2001-03-06
AU722412B2 (en) 2000-08-03
WO1996034957A1 (en) 1996-11-07
CA2218034A1 (en) 1996-11-07
EP0826048A1 (en) 1998-03-04
JPH11505418A (ja) 1999-05-21
AU5852396A (en) 1996-11-21
US5804376A (en) 1998-09-08
US6013448A (en) 2000-01-11

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