MX9705366A - Una quimiocina novedosa expresada en bazo fetal, su produccion y usos. - Google Patents
Una quimiocina novedosa expresada en bazo fetal, su produccion y usos.Info
- Publication number
- MX9705366A MX9705366A MX9705366A MX9705366A MX9705366A MX 9705366 A MX9705366 A MX 9705366A MX 9705366 A MX9705366 A MX 9705366A MX 9705366 A MX9705366 A MX 9705366A MX 9705366 A MX9705366 A MX 9705366A
- Authority
- MX
- Mexico
- Prior art keywords
- fsec
- production
- fetal spleen
- encode
- antibodies capable
- Prior art date
Links
- 102000019034 Chemokines Human genes 0.000 title abstract 3
- 108010012236 Chemokines Proteins 0.000 title abstract 3
- 230000001605 fetal effect Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 210000000952 spleen Anatomy 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 210000004989 spleen cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invencion proporciona secuencias de nucleotidos y aminoácidos que identifican y codifican una quimiocina novedosa (FSEC) que se encuentra inicialmente en células de bazo fetal humano. La presente invencion también proporciona moléculas anti-sentido a la secuencias de nucleotidos que codifican a FSEC, vectores de expresion para la produccion FSEC purificado, anticuerpos capaces de fijarse específicamente a FSEC, sondas de hibridacion u oligonucleotidos para la deteccion de secuencias de nucleotidos que codifican a FSEC, células huésped genéticamente diseñadas para la expresion de FSEC, pruebas de diagnostico para la activacion de quimiocina en base a las moléculas de ácido nucleico que codifican al FSEC y anticuerpos capaces de fijarse específicamente a FSEC.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08375346 | 1995-01-19 | ||
| US08/375,346 US5605817A (en) | 1995-01-19 | 1995-01-19 | DNA encoding chemokine expressed in fetal spleen |
| PCT/US1996/000920 WO1996022374A1 (en) | 1995-01-19 | 1996-01-19 | A new chemokine expressed in fetal spleen, its production and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9705366A true MX9705366A (es) | 1997-10-31 |
| MXPA97005366A MXPA97005366A (es) | 1998-07-03 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| AU717721B2 (en) | 2000-03-30 |
| US5945506A (en) | 1999-08-31 |
| US5605817A (en) | 1997-02-25 |
| WO1996022374A1 (en) | 1996-07-25 |
| AU5168096A (en) | 1996-08-07 |
| JPH10513045A (ja) | 1998-12-15 |
| US20020142398A1 (en) | 2002-10-03 |
| CA2207009A1 (en) | 1996-07-25 |
| EP0807177A1 (en) | 1997-11-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9708427A (es) | Serpina derivada de pancreas. | |
| DE69534196D1 (de) | Hu-B1.219, EIN NEUARTIGER HÄMATOPOIETINREZEPTOR | |
| WO1998050554A3 (en) | Enterococcus faecalis polynucleotides and polypeptides | |
| BR9704260A (pt) | Polimerase de dna termoestável modificada | |
| WO2002055985A3 (en) | Methods and reagents for identifying rare fetal cells in the material circulation | |
| WO1996040040A3 (en) | Thrombin receptor homolog | |
| EP1734134A3 (en) | A novel, prostate-specific gene for diagnosis, prognosis and management of prostate cancer | |
| WO1998006841A3 (en) | Two human nsp-like proteins | |
| MX9709338A (es) | Receptor de transmembrana-siete de tipo c5a. | |
| WO1998031795A3 (en) | Novel human metallothionein | |
| WO1998018822A3 (en) | Novel human lim proteins | |
| WO1996029407A3 (en) | Cellubrevin homologs | |
| WO1998025956A3 (en) | Human GTP-binding proteins | |
| WO1998011232A3 (en) | Human nm23-like protein | |
| WO1996028549A3 (en) | Hyaluronan receptor expressed in human umbilical vein endothelial cells | |
| MX9701596A (es) | Un homologo de quinasa de proteina activada por mitogeno humana. | |
| MX9705366A (es) | Una quimiocina novedosa expresada en bazo fetal, su produccion y usos. | |
| MX9706158A (es) | Quimiocinas novedosas expresadas en pancreas. | |
| MX9709337A (es) | Receptor p2u purinergico humano novedoso. | |
| WO1998031805A3 (en) | Human zinc binding proteins | |
| MX9709270A (es) | Homologo de enzima de conversion de interleucina-1 humana. | |
| MX9708030A (es) | Nuevo homologo de captecina c. | |
| MX9707880A (es) | Quimiocina novedosa expresada en eosinofilos. | |
| MX9704276A (es) | Una quimiocina novedosa expresada en adenoides inflamadas, su produccion y usos. | |
| MX9707852A (es) | Homologo de fosfolipasa c. |