|
US1132581A
(en)
*
|
|
1915-03-23 |
Automobil Construktions Ges M B H Deutsche |
Method of operating combustion-engines.
|
|
US3980781A
(en)
*
|
1966-03-31 |
1976-09-14 |
Imperial Chemical Industries Limited |
Fungicidal composition and method containing 2-amino-pyrimidines
|
|
US4000138A
(en)
*
|
1966-03-31 |
1976-12-28 |
Imperial Chemical Industries Limited |
Organic compounds and compositions containing them
|
|
US4062950A
(en)
|
1973-09-22 |
1977-12-13 |
Bayer Aktiengesellschaft |
Amino sugar derivatives
|
|
US3914250A
(en)
|
1974-08-01 |
1975-10-21 |
American Home Prod |
1,4-Diazepino{8 6,5,4-jk{9 carbazoles
|
|
JPS608117B2
(ja)
|
1977-02-08 |
1985-02-28 |
財団法人微生物化学研究会 |
新生理活性物質エステラスチンおよびその製造法
|
|
DE2716677C2
(de)
|
1977-04-15 |
1985-10-10 |
Hoechst Ag, 6230 Frankfurt |
Cephemderivate und Verfahren zu ihrer Herstellung
|
|
DE2714880A1
(de)
|
1977-04-02 |
1978-10-26 |
Hoechst Ag |
Cephemderivate und verfahren zu ihrer herstellung
|
|
DE2719912C3
(de)
|
1977-05-04 |
1979-12-06 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen
|
|
NO154918C
(no)
|
1977-08-27 |
1987-01-14 |
Bayer Ag |
Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
|
|
JPS5953920B2
(ja)
|
1977-12-28 |
1984-12-27 |
東洋醸造株式会社 |
新規なアミノ糖化合物およびその製法
|
|
CA1121290A
(en)
|
1978-02-14 |
1982-04-06 |
Yasuji Suhara |
Amino sugar derivatives
|
|
DE2928485A1
(de)
|
1979-07-14 |
1981-01-29 |
Bayer Ag |
Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
|
|
ES505959A0
(es)
|
1980-10-09 |
1982-09-01 |
Hoechst Ag |
Procedimiento para la preparacion de un inactivador de alfa-amilasa
|
|
EP0056194B1
(en)
|
1981-01-05 |
1984-09-12 |
Takeda Chemical Industries, Ltd. |
N-substituted pseudo-aminosugars, their production and use
|
|
ZA821577B
(en)
|
1981-04-06 |
1983-03-30 |
Boots Co Plc |
Therapeutic agents
|
|
US4452813A
(en)
|
1981-05-22 |
1984-06-05 |
Taiho Pharmaceutical Company Limited |
Sulfonate derivatives, process for preparing same and antilipemic compositions containing the derivative
|
|
CA1247547A
(en)
|
1983-06-22 |
1988-12-28 |
Paul Hadvary |
Leucine derivatives
|
|
FI844289A7
(fi)
|
1984-01-21 |
1985-07-22 |
Hoechst Ag |
Uusia polypeptidejä, joilla on -amylaasi-estävä vaikutus, niiden käyttö ja farmaseuttiset valmistee
|
|
US4713313A
(en)
|
1984-05-02 |
1987-12-15 |
Polaroid Corporation |
Photographic system and novel compounds
|
|
US4780126A
(en)
|
1984-08-30 |
1988-10-25 |
Bayer Aktiengesellschaft |
3-substituted 1-(2-halogenoalkoxy-benzenesulphonyl)-3-heteroaryl-(thio)ureas
|
|
US4634765A
(en)
|
1984-12-18 |
1987-01-06 |
Merrell Dow Pharmaceuticals Inc. |
Homodisaccharide hypoglycemic agents
|
|
FR2593178B1
(fr)
|
1986-01-20 |
1988-04-29 |
Esteve Labor Dr |
Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
|
|
US4751237A
(en)
|
1986-01-27 |
1988-06-14 |
Merck & Co., Inc. |
Antihypercholesterolemic beta-lactones
|
|
US4847271A
(en)
|
1986-01-27 |
1989-07-11 |
Merck & Co., Inc. |
Antihypercholesterolemic β-lactones
|
|
DE3642824A1
(de)
|
1986-12-16 |
1988-06-30 |
Bayer Ag |
Substituierte 1-benzylsulfonyl-3-heteroaryl-(thio)harnstoffe
|
|
US4816477A
(en)
|
1987-05-26 |
1989-03-28 |
Merck & Co., Inc. |
Antihypercholesterolemic β-lactones
|
|
US4806564A
(en)
|
1987-05-26 |
1989-02-21 |
Merck & Co., Inc. |
Antihypercholesterolemic beta-lactones
|
|
IL86941A
(en)
|
1987-07-10 |
1993-07-08 |
Gist Brocades Nv |
Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process
|
|
DE3723327A1
(de)
|
1987-07-15 |
1989-02-02 |
Hoechst Ag |
Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen
|
|
JPH01132581A
(ja)
*
|
1987-11-18 |
1989-05-25 |
Yoshitomi Pharmaceut Ind Ltd |
ピリミジン化合物
|
|
NZ227042A
(en)
|
1987-11-27 |
1991-05-28 |
Banyu Pharma Co Ltd |
Substituted alkylamine derivatives and pharmaceutical compositions
|
|
US5192772A
(en)
|
1987-12-09 |
1993-03-09 |
Nippon Shinyaku Co. Ltd. |
Therapeutic agents
|
|
JPH01216997A
(ja)
|
1988-02-24 |
1989-08-30 |
Fujisawa Pharmaceut Co Ltd |
新規セフェム化合物ならびにその製造法
|
|
EP0344383A1
(en)
|
1988-06-02 |
1989-12-06 |
Merrell Dow Pharmaceuticals Inc. |
Novel alpha-Glucosidase inhibitors
|
|
DE3836675A1
(de)
|
1988-10-28 |
1990-05-03 |
Hoechst Ag |
Glykosidase-inhibitor salbostatin, verfahren zu seiner herstellung und seine verwendung
|
|
IE61928B1
(en)
|
1988-11-29 |
1994-11-30 |
Boots Co Plc |
Treatment of obesity
|
|
JPH02169571A
(ja)
|
1988-12-22 |
1990-06-29 |
Banyu Pharmaceut Co Ltd |
置換アリルアミン誘導体
|
|
US5236917A
(en)
|
1989-05-04 |
1993-08-17 |
Sterling Winthrop Inc. |
Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof
|
|
US5064856A
(en)
|
1989-07-31 |
1991-11-12 |
Merck & Co., Inc. |
Novel hmg-coa synthase inhibitors
|
|
US5256675A
(en)
|
1989-08-07 |
1993-10-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same
|
|
US4983597A
(en)
|
1989-08-31 |
1991-01-08 |
Merck & Co., Inc. |
Beta-lactams as anticholesterolemic agents
|
|
US5391571A
(en)
|
1989-11-15 |
1995-02-21 |
American Home Products Corporation |
Cholesterol ester hydrolase inhibitors
|
|
US5112820A
(en)
|
1990-03-05 |
1992-05-12 |
Sterling Drug Inc. |
Anti-glaucoma compositions containing 2- and 3-aminomethyl-6-arylcarbonyl- or 6-phenylthio-2,3-dihydropyrrolo-(1,2,3-de)-1,4-benzoxazines and method of use thereof
|
|
US5081122A
(en)
|
1990-03-05 |
1992-01-14 |
Sterling Drug Inc. |
Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
|
|
US4973587A
(en)
|
1990-03-08 |
1990-11-27 |
Sterling Drug Inc. |
3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method
|
|
US5013837A
(en)
|
1990-03-08 |
1991-05-07 |
Sterling Drug Inc. |
3-Arylcarbonyl-1H-indole-containing compounds
|
|
US5504078A
(en)
|
1990-06-08 |
1996-04-02 |
Merrell Dow Pharmaceuticals Inc. |
α-glucosidase inhibitors
|
|
US5120729A
(en)
|
1990-06-20 |
1992-06-09 |
Merck & Co., Inc. |
Beta-lactams as antihypercholesterolemics
|
|
FR2665159B1
(fr)
|
1990-07-24 |
1992-11-13 |
Rhone Poulenc Sante |
Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
US5091418A
(en)
|
1990-09-28 |
1992-02-25 |
Bristol-Myers Squibb Company |
Novel alpha-glucosidase inhibitor, pradimicin Q
|
|
US5217877A
(en)
|
1990-09-28 |
1993-06-08 |
Bristol-Myers Squibb Company |
Process for the preparation of α-glucosidase inhibitor, pradimicin Q
|
|
US5472967A
(en)
|
1991-02-20 |
1995-12-05 |
Synthelabo |
4-pyrimidinone derivatives their preparation and their application in therapy
|
|
US5182298A
(en)
|
1991-03-18 |
1993-01-26 |
Merck & Co., Inc. |
Cholesterol lowering agents
|
|
GB9105771D0
(en)
|
1991-03-19 |
1991-05-01 |
Cancer Res Inst Royal |
Anti-cancer compounds
|
|
IL101850A
(en)
|
1991-06-13 |
1996-01-31 |
Janssen Pharmaceutica Nv |
11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
|
|
DE4243287A1
(de)
*
|
1992-06-19 |
1993-12-23 |
Basf Ag |
N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
|
|
FR2692575B1
(fr)
|
1992-06-23 |
1995-06-30 |
Sanofi Elf |
Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
US5349056A
(en)
|
1992-10-09 |
1994-09-20 |
Regeneron Pharmaceuticals |
Modified ciliary neurotrophic factors
|
|
US6472178B1
(en)
|
1998-02-27 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
|
|
AU676703B2
(en)
|
1992-12-04 |
1997-03-20 |
Janssen Pharmaceutica N.V. |
Antiallergic triazolo(pyrrolo, thieno or furano)azepine derivatives
|
|
EP0672047B1
(en)
|
1992-12-04 |
2003-05-02 |
Janssen Pharmaceutica N.V. |
ANTIALLERGIC IMIDAZO[1,2-a]THIENO[ 2,3-d]AZEPINE DERIVATIVES
|
|
WO1994013671A1
(en)
|
1992-12-04 |
1994-06-23 |
Janssen Pharmaceutica N.V. |
Antiallergic triazolobenzazepine derivatives
|
|
US5451677A
(en)
|
1993-02-09 |
1995-09-19 |
Merck & Co., Inc. |
Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
|
|
US5292736A
(en)
|
1993-02-26 |
1994-03-08 |
Sterling Winthrop Inc. |
Morpholinoalkylindenes as antiglaucoma agents
|
|
TW252112B
(enExample)
|
1993-08-19 |
1995-07-21 |
Pfizer |
|
|
FR2714057B1
(fr)
|
1993-12-17 |
1996-03-08 |
Sanofi Elf |
Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
|
|
IL112290A
(en)
|
1994-01-12 |
1999-01-26 |
Novartis Ag |
Transformed aryl and the troiryl pyrimidines and herbicides containing them
|
|
US5705515A
(en)
|
1994-04-26 |
1998-01-06 |
Merck & Co., Inc. |
Substituted sulfonamides as selective β-3 agonists for the treatment of diabetes and obesity
|
|
EP0685466A1
(de)
|
1994-06-02 |
1995-12-06 |
Ciba-Geigy Ag |
3-Heteroaliphatyl- und 3-Hetero-(aryl)aliphatyl-2(1H)-chinolonderivate
|
|
US5888420A
(en)
|
1994-06-13 |
1999-03-30 |
Mitsui Chemicals, Inc. |
Liquid crystal device and process for preparing the same
|
|
JPH0862604A
(ja)
|
1994-06-13 |
1996-03-08 |
Mitsui Petrochem Ind Ltd |
液晶素子およびその製造方法
|
|
BR9509610A
(pt)
|
1994-11-07 |
1997-10-28 |
Pfizer |
Ligandos específicos de neuropeptideo Y1
|
|
US5605886A
(en)
|
1995-01-31 |
1997-02-25 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552522A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5521283A
(en)
|
1995-01-31 |
1996-05-28 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552524A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
AU4766096A
(en)
|
1995-01-31 |
1996-08-21 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552523A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5559208A
(en)
|
1995-01-31 |
1996-09-24 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
WO1996023517A1
(en)
|
1995-01-31 |
1996-08-08 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5554727A
(en)
|
1995-01-31 |
1996-09-10 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5760038A
(en)
|
1995-02-06 |
1998-06-02 |
Bristol-Myers Squibb Company |
Substituted biphenyl sulfonamide endothelin antagonists
|
|
US5780473A
(en)
|
1995-02-06 |
1998-07-14 |
Bristol-Myers Squibb Company |
Substituted biphenyl sulfonamide endothelin antagonists
|
|
US5532237A
(en)
|
1995-02-15 |
1996-07-02 |
Merck Frosst Canada, Inc. |
Indole derivatives with affinity for the cannabinoid receptor
|
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
|
US20020006964A1
(en)
|
1995-05-16 |
2002-01-17 |
Young James W. |
Methods of using and compositions comprising (+) sibutramine optionally in combination with other pharmacologically active compounds
|
|
JPH08327993A
(ja)
|
1995-05-30 |
1996-12-13 |
Mitsui Petrochem Ind Ltd |
液晶素子
|
|
US5739106A
(en)
|
1995-06-07 |
1998-04-14 |
Rink; Timothy J. |
Appetite regulating compositions
|
|
GB9522007D0
(en)
|
1995-10-27 |
1996-01-03 |
Fujisawa Pharmaceutical Co |
New compound
|
|
FR2741621B1
(fr)
|
1995-11-23 |
1998-02-13 |
Sanofi Sa |
Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
AU7692896A
(en)
|
1995-12-01 |
1997-06-27 |
Novartis Ag |
Quinazolin-2,4-diazirines as NPY receptor antagonist
|
|
AU1328197A
(en)
|
1995-12-01 |
1997-06-19 |
Synaptic Pharmaceutical Corporation |
Aryl sulfonamide and sulfamide derivatives and uses thereof
|
|
AU7692996A
(en)
|
1995-12-01 |
1997-06-27 |
Ciba-Geigy Ag |
Receptor antagonists
|
|
AU7626496A
(en)
|
1995-12-01 |
1997-06-27 |
Ciba-Geigy Ag |
Heteroaryl compounds
|
|
AU7692696A
(en)
|
1995-12-01 |
1997-06-27 |
Novartis Ag |
Heteroaryl derivatives
|
|
TW432073B
(en)
|
1995-12-28 |
2001-05-01 |
Pfizer |
Pyrazolopyridine compounds
|
|
AU1295597A
(en)
|
1995-12-29 |
1997-07-28 |
Smithkline Beecham Corporation |
Vitronectin receptor antagonists
|
|
ATE236137T1
(de)
|
1996-02-02 |
2003-04-15 |
Merck & Co Inc |
Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit
|
|
CA2244831A1
(en)
|
1996-02-02 |
1997-08-07 |
John T. Olson |
Method of treating diabetes and related disease states
|
|
JP2002503202A
(ja)
|
1996-02-02 |
2002-01-29 |
メルク エンド カンパニー インコーポレーテッド |
抗糖尿病薬
|
|
CA2245524A1
(en)
|
1996-02-02 |
1997-08-07 |
Wei Han |
Antidiabetic agents
|
|
AU1618697A
(en)
|
1996-02-06 |
1997-08-28 |
Japan Tobacco Inc. |
Novel compounds and pharmaceutical use thereof
|
|
JPH09274290A
(ja)
|
1996-02-07 |
1997-10-21 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真感光材料用の現像液および処理方法
|
|
CN1161202A
(zh)
|
1996-03-14 |
1997-10-08 |
袁安令 |
无伤疤复原型烧烫伤药品配方
|
|
ATE227293T1
(de)
|
1996-05-15 |
2002-11-15 |
Pfizer |
2,3-disubstituierte-(5,6)-heteroarylkondensiert - pyrimidin-4-one
|
|
IT1288388B1
(it)
|
1996-11-19 |
1998-09-22 |
Angeletti P Ist Richerche Bio |
Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
|
|
CA2274594C
(en)
|
1996-12-16 |
2006-10-10 |
Banyu Pharmaceutical Co., Ltd. |
Aminopyrazole derivatives
|
|
JPH10237049A
(ja)
|
1996-12-24 |
1998-09-08 |
Nippon Chemiphar Co Ltd |
ベンズイソキサゾ−ル誘導体
|
|
JP4798814B2
(ja)
|
1997-01-07 |
2011-10-19 |
アミリン・ファーマシューティカルズ，インコーポレイテッド |
食物摂取低減用のエキセンジンおよびそのアゴニストの使用
|
|
JP2001508799A
(ja)
|
1997-01-21 |
2001-07-03 |
スミスクライン・ビーチャム・コーポレイション |
新規カンナビノイド受容体モジュレータ
|
|
KR100510794B1
(ko)
|
1997-02-04 |
2005-08-31 |
더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 |
살진균 카르복스아미드
|
|
HU228509B1
(en)
|
1997-02-21 |
2013-03-28 |
Bayer Ip Gmbh |
Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases
|
|
CA2283797A1
(en)
|
1997-03-18 |
1998-09-24 |
Paul Elliot Bender |
Novel cannabinoid receptor agonists
|
|
FR2761266B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates
|
|
FR2761265B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique pour l'administration orale d'un derive du n-piperidino-3-pyrazolecarboxamide, de ses sels et de leurs solvates
|
|
WO1998047505A1
(en)
|
1997-04-23 |
1998-10-29 |
Banyu Pharmaceutical Co., Ltd. |
Neuropeptide y receptor antagonist
|
|
US6001836A
(en)
|
1997-05-28 |
1999-12-14 |
Bristol-Myers Squibb Company |
Dihydropyridine NPY antagonists: cyanoguanidine derivatives
|
|
SE9702457D0
(sv)
|
1997-06-26 |
1997-06-26 |
Pharmacia & Upjohn Ab |
Screening
|
|
AU8127998A
(en)
|
1997-07-11 |
1999-02-08 |
Japan Tobacco Inc. |
Quinoline compounds and medicinal uses thereof
|
|
US6251912B1
(en)
|
1997-08-01 |
2001-06-26 |
American Cyanamid Company |
Substituted quinazoline derivatives
|
|
US6369067B1
(en)
|
1997-10-27 |
2002-04-09 |
Dr. Reddy's Research Foundation |
Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
|
|
AU756836B2
(en)
|
1997-11-14 |
2003-01-23 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
JPH11209366A
(ja)
|
1998-01-23 |
1999-08-03 |
Nissan Chem Ind Ltd |
クロマン誘導体及び心不全治療薬
|
|
JPH11279158A
(ja)
|
1998-02-09 |
1999-10-12 |
Pfizer Prod Inc |
キナゾリン―４―オン誘導体の製造方法
|
|
WO1999041237A1
(en)
*
|
1998-02-13 |
1999-08-19 |
G.D. Searle & Co. |
Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity
|
|
EP1068207A1
(en)
|
1998-04-02 |
2001-01-17 |
Neurogen Corporation |
AMINOALKYL SUBSTITUTED 9H-PYRIDINO 2,3-b]INDOLE AND 9H-PYRIMIDINO 4,5-b]INDOLE DERIVATIVES
|
|
EP1073643B1
(en)
|
1998-04-23 |
2004-12-29 |
Dr. Reddy's Laboratories Ltd. |
New heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
|
|
EP1073637B1
(en)
|
1998-04-27 |
2006-08-02 |
Centre National De La Recherche Scientifique |
3-(amino- or aminoalkyl)pyridinone derivatives and their use for the treatment of hiv related diseases
|
|
DK1076644T3
(da)
|
1998-04-29 |
2004-08-30 |
Ortho Mcneil Pharm Inc |
N-Substituerede aminotetraliner som ligander for neutopeptid Y Y5-receptoren, der er nyttig til behandling af fedme og andre lidelser
|
|
US6329395B1
(en)
|
1998-06-08 |
2001-12-11 |
Schering Corporation |
Neuropeptide Y5 receptor antagonists
|
|
EP1085869A4
(en)
|
1998-06-11 |
2001-10-04 |
Merck & Co Inc |
Spiropiperidine derivatives as melanocortin receptor agonists
|
|
DE19837627A1
(de)
|
1998-08-19 |
2000-02-24 |
Bayer Ag |
Neue Aminosäureester von Arylsulfonamiden und Analoga
|
|
HN1998000027A
(es)
|
1998-08-19 |
1999-06-02 |
Bayer Ip Gmbh |
Arilsulfonamidas y analagos
|
|
US6358951B1
(en)
|
1998-08-21 |
2002-03-19 |
Pfizer Inc. |
Growth hormone secretagogues
|
|
GT199900147A
(es)
|
1998-09-17 |
1999-09-06 |
|
1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
|
|
US6337332B1
(en)
|
1998-09-17 |
2002-01-08 |
Pfizer Inc. |
Neuropeptide Y receptor antagonists
|
|
US6147090A
(en)
|
1998-09-17 |
2000-11-14 |
Pfizer Inc. |
4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
|
|
US6147089A
(en)
|
1998-09-17 |
2000-11-14 |
Pfizer Inc. |
Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
|
|
US6197786B1
(en)
|
1998-09-17 |
2001-03-06 |
Pfizer Inc |
4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
|
|
US6297258B1
(en)
|
1998-09-29 |
2001-10-02 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
|
BRPI9914164B8
(pt)
|
1998-09-29 |
2021-05-25 |
American Cyanamid Co |
compostos de 3-ciano quinolina
|
|
US6147018A
(en)
|
1998-09-29 |
2000-11-14 |
E. I. Du Pont De Nemours And Company |
Hybrid protective composite
|
|
US7417038B1
(en)
|
1998-10-15 |
2008-08-26 |
Imperial Innovations Limited |
Methods of treating cachexia
|
|
ATE314371T1
(de)
|
1998-11-10 |
2006-01-15 |
Merck & Co Inc |
Spiro-indole als y5-rezeptor antagonisten
|
|
ES2161594B1
(es)
|
1998-12-17 |
2003-04-01 |
Servier Lab |
Nuevos derivados de la hidrazida, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
|
|
WO2000037470A1
(en)
|
1998-12-19 |
2000-06-29 |
Janssen Pharmaceutica N.V. |
Antihistaminic spiro compounds
|
|
US6844368B1
(en)
|
1998-12-22 |
2005-01-18 |
Edward Roberts |
Compounds useful in pain management
|
|
US6344481B1
(en)
|
1999-03-01 |
2002-02-05 |
Pfizer Inc. |
Thyromimetic antiobesity agents
|
|
CA2367666C
(en)
|
1999-03-19 |
2008-11-25 |
Carl M. Mendel |
Method of treating eating disorders
|
|
AU2830800A
(en)
|
1999-03-25 |
2000-10-16 |
Nissan Chemical Industries Ltd. |
Chroman derivatives
|
|
FR2792314B1
(fr)
|
1999-04-15 |
2001-06-01 |
Adir |
Nouveaux composes aminotriazoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
PT1183245E
(pt)
|
1999-04-22 |
2007-07-12 |
Lundbeck & Co As H |
Antagonistas selectivos de npy (y5)
|
|
US6340683B1
(en)
|
1999-04-22 |
2002-01-22 |
Synaptic Pharmaceutical Corporation |
Selective NPY (Y5) antagonists (triazines)
|
|
AU4659200A
(en)
|
1999-05-05 |
2000-11-21 |
Ortho-Mcneil Pharmaceutical, Inc. |
3a,4,5,9b-tetrahydro-1h-benz(e)indol-2-yl amine-derived neuropeptide Y receptors ligands useful in the treatment of obesity and other disorders
|
|
AU778393B2
(en)
|
1999-05-12 |
2004-12-02 |
Ortho-Mcneil Pharmaceutical, Inc. |
Pyrazole carboxamides useful for the treatment of obesity and other disorders
|
|
CA2377369A1
(en)
|
1999-06-04 |
2000-12-14 |
Merck & Co., Inc. |
Substituted piperidines as melanocortin-4 receptor agonists
|
|
DE60023141T2
(de)
|
1999-06-30 |
2006-06-14 |
Lundbeck As Valby H |
Selektive npy (y5) antagonisten
|
|
AU6000900A
(en)
|
1999-07-23 |
2001-02-13 |
Astrazeneca Uk Limited |
Carbazole derivatives and their use as neuropeptide y5 receptor ligands
|
|
MXPA02000927A
(es)
|
1999-07-28 |
2003-07-14 |
Johnson & Johnson |
Amina y derivados de amida como ligandos para el receptor del neuropeptido y y5 utiles en el tratamiento de obesidad y otros trastornos.
|
|
TWI279402B
(en)
|
1999-08-20 |
2007-04-21 |
Banyu Pharma Co Ltd |
Spiro compounds having NPY antagonistic activities and agents containing the same
|
|
ES2258476T3
(es)
|
1999-09-30 |
2006-09-01 |
Neurogen Corporation |
Ciertos heterociclos sustituidos con alquilendiaminas.
|
|
JP2003510325A
(ja)
|
1999-09-30 |
2003-03-18 |
ニューロジェン・コーポレーション |
ある種のアルキレンジアミン−置換ピラゾロ［１，５−ａ］−１，５−ピリミジン及びピラゾロ［１，５−ａ］−１，３，５−トリアジン
|
|
EP1218381B1
(en)
|
1999-09-30 |
2006-12-06 |
Neurogen Corporation |
AMINO SUBSTITUTED PYRAZOLO¬1,5-a|-1,5-PYRIMIDINES AND PYRAZOLO¬1,5-a|-1,3,5-TRIAZINES
|
|
WO2001027068A1
(en)
|
1999-10-13 |
2001-04-19 |
Pfizer Products Inc. |
Biaryl ether derivatives useful as monoamine reuptake inhibitors
|
|
DE19949319A1
(de)
|
1999-10-13 |
2001-06-13 |
Ruetgers Vft Ag |
Verfahren zur Herstellung von Arylalkylethern
|
|
AR032292A1
(es)
|
1999-12-16 |
2003-11-05 |
Schering Corp |
Imidazoles sustituidos, composiciones farmaceuticas y el uso de dichos imidazoles para la manufactura de un medicamento para los tratamientos de desordenes en la alimentacion
|
|
US7345051B2
(en)
|
2000-01-31 |
2008-03-18 |
Genaera Corporation |
Mucin synthesis inhibitors
|
|
DE60127098T2
(de)
|
2000-01-31 |
2007-11-29 |
Genaera Corp. |
Inhibitoren der mucin-synthese
|
|
AU2001228325A1
(en)
|
2000-02-01 |
2001-08-14 |
Novo-Nordisk A/S |
Use of compounds for the regulation of food intake
|
|
WO2001057018A1
(en)
|
2000-02-02 |
2001-08-09 |
Abbott Laboratories |
Azaazulene inhibitors of p38 map kinase and tnf-alpha
|
|
US6653304B2
(en)
|
2000-02-11 |
2003-11-25 |
Bristol-Myers Squibb Co. |
Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
|
|
SI1686119T1
(sl)
|
2000-02-16 |
2009-12-31 |
Smithkline Beecham Plc |
Derivati pirimidin-5-ona kot inhibitorji ldl-pla2
|
|
GB0004003D0
(en)
|
2000-02-22 |
2000-04-12 |
Knoll Ag |
Therapeutic agents
|
|
AU2001234128B2
(en)
|
2000-02-22 |
2004-11-11 |
Banyu Pharmaceutical Co., Ltd. |
Novel imidazoline compounds
|
|
US6531478B2
(en)
|
2000-02-24 |
2003-03-11 |
Cheryl P. Kordik |
Amino pyrazole derivatives useful for the treatment of obesity and other disorders
|
|
FR2805817B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
|
|
FR2805810B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
|
|
FR2805818B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
|
|
EP1132389A1
(en)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
New aza-indolyl derivatives for the treatment of obesity
|
|
US6384051B1
(en)
|
2000-03-13 |
2002-05-07 |
American Cyanamid Company |
Method of treating or inhibiting colonic polyps
|
|
AU2001260113B2
(en)
|
2000-03-14 |
2006-04-06 |
Actelion Pharmaceuticals Ltd. |
1,2,3,4-tetrahydroisoquinoline derivatives
|
|
CA2403631A1
(en)
|
2000-03-23 |
2001-09-27 |
Brenda L. Palucki |
Spiropiperidine derivatives as melanocortin receptor agonists
|
|
JP2003528088A
(ja)
|
2000-03-23 |
2003-09-24 |
メルク エンド カムパニー インコーポレーテッド |
メラノコルチン受容体作働薬としての置換ピペリジン類
|
|
US6600015B2
(en)
|
2000-04-04 |
2003-07-29 |
Hoffmann-La Roche Inc. |
Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity
|
|
EP1142886A1
(en)
|
2000-04-07 |
2001-10-10 |
Aventis Pharma Deutschland GmbH |
Percyquinnin, a process for its production and its use as a pharmaceutical
|
|
CA2407149C
(en)
|
2000-04-28 |
2010-10-12 |
Takeda Chemical Industries, Ltd. |
Melanin-concentrating hormone antagonist
|
|
GB0010757D0
(en)
|
2000-05-05 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0011013D0
(en)
|
2000-05-09 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
|
US6432960B2
(en)
|
2000-05-10 |
2002-08-13 |
Bristol-Myers Squibb Company |
Squarate derivatives of dihydropyridine NPY antagonists
|
|
US6444675B2
(en)
|
2000-05-10 |
2002-09-03 |
Bristol-Myers Squibb Company |
4-alkyl and 4-cycloalkyl derivatives of dihydropyridine NPY antagonists
|
|
WO2001085173A1
(en)
|
2000-05-10 |
2001-11-15 |
Bristol-Myers Squibb Company |
Alkylamine derivatives of dihydropyridine npy antagonists
|
|
CA2408486A1
(en)
|
2000-05-11 |
2001-11-15 |
Bristol-Myers Squibb Company |
Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
|
|
CA2408913A1
(en)
|
2000-05-16 |
2001-11-22 |
Takeda Chemical Industries, Ltd. |
Melanin-concentrating hormone antagonist
|
|
AU2001259056A1
(en)
|
2000-05-17 |
2001-11-26 |
Eli Lilly And Company |
Method for selectively inhibiting ghrelin action
|
|
US6391881B2
(en)
|
2000-05-19 |
2002-05-21 |
Bristol-Myers Squibb Company |
Thiourea derivatives of dihydropyridine NPY antagonists
|
|
SE0001899D0
(sv)
|
2000-05-22 |
2000-05-22 |
Pharmacia & Upjohn Ab |
New compounds
|
|
CA2410597A1
(en)
|
2000-05-30 |
2001-12-06 |
Merck & Co., Inc. |
Melanocortin receptor agonists
|
|
AU2000252458A1
(en)
*
|
2000-06-08 |
2001-12-17 |
Shizuoka Coffein Co., Ltd. |
Benzene derivatives
|
|
IL153273A0
(en)
|
2000-06-09 |
2003-07-06 |
Aventis Pharma Gmbh |
Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
|
|
WO2001096307A2
(en)
|
2000-06-15 |
2001-12-20 |
Pharmacia Corporation |
Cycloalkyl alkanoic acids as integrin receptor antagonists
|
|
US6921767B2
(en)
|
2000-06-15 |
2005-07-26 |
Pharmacia Corporation |
Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
|
|
ES2238458T3
(es)
|
2000-06-16 |
2005-09-01 |
Smithkline Beecham Plc |
Piperidinas para uso como antagonistas de los receptores de orexina.
|
|
EP1299362A4
(en)
|
2000-07-05 |
2004-11-03 |
Synaptic Pharma Corp |
SELECTIVE RECEPTOR ANTAGONISTS OF MELANINE CONCENTRATING HORMON-1 (MCH1) AND THEIR USE
|
|
MXPA03000174A
(es)
|
2000-07-06 |
2003-09-22 |
Neurogen Corp |
Ligandos de receptor de hormona concentradora de melanina.
|
|
WO2002004464A1
(en)
|
2000-07-07 |
2002-01-17 |
Lg Life Sciences Ltd |
Novel cephalosporin compounds and process for preparing the same
|
|
GB0019357D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel phenyl guanidines
|
|
CN1443198A
(zh)
|
2000-07-24 |
2003-09-17 |
阿达纳生物科学有限公司 |
Ghrelin拮抗剂
|
|
CN1277828C
(zh)
|
2000-07-31 |
2006-10-04 |
霍夫曼-拉罗奇有限公司 |
哌嗪衍生物
|
|
US6768024B1
(en)
|
2000-08-04 |
2004-07-27 |
Lion Bioscience Ag |
Triamine derivative melanocortin receptor ligands and methods of using same
|
|
GB0019359D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel guanidines
|
|
EP1310494B1
(en)
|
2000-08-11 |
2012-01-25 |
Nippon Chemiphar Co., Ltd. |
PPAR (delta) ACTIVATORS
|
|
WO2002015905A1
(en)
|
2000-08-21 |
2002-02-28 |
Gliatech, Inc. |
The use of histamine h3 receptor inverse agonists for the control of appetite and treatment of obesity
|
|
AU2001288294A1
(en)
|
2000-08-21 |
2002-03-04 |
Merck And Co., Inc. |
Anti-hypercholesterolemic drug combination
|
|
EP1320366A4
(en)
|
2000-08-23 |
2005-04-06 |
Merck & Co Inc |
SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS
|
|
GB0021831D0
(en)
|
2000-09-06 |
2000-10-18 |
Astrazeneca Ab |
Chemical compounds
|
|
US6900226B2
(en)
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
|
JP2004509108A
(ja)
|
2000-09-14 |
2004-03-25 |
シェーリング コーポレイション |
置換尿素神経ペプチドｙｙ５受容体アンタゴニスト
|
|
AU2001292480A1
(en)
|
2000-09-26 |
2002-04-08 |
Biovitrum Ab |
Novel pyridazine compounds for the treatment of diabetes
|
|
AU2001292518A1
(en)
|
2000-09-26 |
2002-04-08 |
Biovitrum Ab |
Novel compounds
|
|
JP2002114768A
(ja)
|
2000-10-11 |
2002-04-16 |
Japan Tobacco Inc |
２−（２，５−ジハロゲン−３，４−ジヒドロキシフェニル）アゾール化合物及びそれを含有してなる医薬組成物
|
|
BR0114630A
(pt)
|
2000-10-13 |
2003-07-01 |
Lilly Co Eli |
Secretagogos de hormÈnio do crescimento
|
|
WO2002044152A1
(en)
|
2000-10-16 |
2002-06-06 |
F. Hoffmann-La Roche Ag |
Indoline derivatives and their use as 5-ht2 receptor ligands
|
|
CN1469876A
(zh)
|
2000-10-20 |
2004-01-21 |
�Ʒ� |
α-芳基乙醇胺及其用作β-3肾上腺素能受体激动剂的用途
|
|
AU2002227170A1
(en)
|
2000-11-03 |
2002-05-15 |
Wyeth |
Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives
|
|
IL155702A0
(en)
|
2000-11-20 |
2003-11-23 |
Biovitrum Ab |
Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5-ht2 receptor
|
|
EP1337518B1
(en)
|
2000-11-20 |
2009-06-17 |
Biovitrum AB (publ) |
Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor
|
|
ATE316965T1
(de)
|
2000-12-06 |
2006-02-15 |
Hoffmann La Roche |
Kondensierte heteroaromatische glucokinaseaktivatoren
|
|
US6566367B2
(en)
|
2000-12-12 |
2003-05-20 |
Pfizer Inc. |
Spiro[isobenzofuran-1,4′-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4′-piperidines
|
|
US6482951B2
(en)
|
2000-12-13 |
2002-11-19 |
Hoffmann-La Roche Inc. |
Isoindolin-1-one glucokinase activators
|
|
GB0030710D0
(en)
|
2000-12-15 |
2001-01-31 |
Hoffmann La Roche |
Piperazine derivatives
|
|
ES2316486T3
(es)
|
2000-12-21 |
2009-04-16 |
Schering Corporation |
Antagonsitas de los receptores y5 del neuropeptido y heteroaril-urea.
|
|
US6472394B1
(en)
|
2000-12-22 |
2002-10-29 |
Schering Corporation |
MCH antagonists and their use in the treatment of obesity
|
|
CN1250549C
(zh)
|
2000-12-27 |
2006-04-12 |
霍夫曼-拉罗奇有限公司 |
吲哚衍生物及其作为5－ht2b和5－ht2c受体配体的应用
|
|
WO2002051232A2
(en)
|
2000-12-27 |
2002-07-04 |
Actelion Pharmaceuticals Ltd. |
Novel benzazepines and related heterocyclic derivatives
|
|
CA2432985A1
(en)
|
2001-01-23 |
2002-08-01 |
Vincent Mancuso |
Piperazine- and piperidine-derivatives as melanocortin receptor agonists
|
|
EP1368339A1
(en)
|
2001-01-23 |
2003-12-10 |
Eli Lilly & Company |
Substituted piperidines/piperazines as melanocortin receptor agonists
|
|
JP2004524297A
(ja)
|
2001-01-23 |
2004-08-12 |
イーライ・リリー・アンド・カンパニー |
メラノコルチン受容体アゴニスト
|
|
KR20030074774A
(ko)
|
2001-02-02 |
2003-09-19 |
다케다 야쿠힌 고교 가부시키가이샤 |
접합 헤테로시클릭 화합물
|
|
US7507767B2
(en)
|
2001-02-08 |
2009-03-24 |
Schering Corporation |
Cannabinoid receptor ligands
|
|
US7067539B2
(en)
|
2001-02-08 |
2006-06-27 |
Schering Corporation |
Cannabinoid receptor ligands
|
|
JP4104983B2
(ja)
|
2001-02-28 |
2008-06-18 |
メルク エンド カムパニー インコーポレーテッド |
メラノコルチン−４受容体作動薬としてのアシル化ピペリジン誘導体
|
|
DE60215132T2
(de)
|
2001-02-28 |
2007-08-23 |
Merck & Co., Inc. |
Acylierte piperidin-derivate als melanocortin-4-rezeptor-agonisten
|
|
AU2002250343B2
(en)
|
2001-02-28 |
2006-05-25 |
Merck Sharp & Dohme Corp. |
Acylated piperidine derivatives as melanocortin-4 receptor agonists
|
|
ES2227451T3
(es)
|
2001-03-08 |
2005-04-01 |
Smithkline Beecham Corporation |
Derivados de pirazolopiridina.
|
|
ATE284872T1
(de)
|
2001-03-22 |
2005-01-15 |
Solvay Pharm Bv |
4,5-dihydro-1h-pyrazolderivate mit cb1- antagonistischer wirkung
|
|
WO2001074782A1
(en)
|
2001-03-29 |
2001-10-11 |
Molecular Design International, Inc. |
β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
|
|
JP4237497B2
(ja)
|
2001-03-30 |
2009-03-11 |
スミスクライン ビーチャム コーポレーション |
ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用
|
|
US7348334B2
(en)
|
2001-04-09 |
2008-03-25 |
Dr. Reddy's Laboratories Limited |
Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them
|
|
WO2002083672A1
(en)
|
2001-04-10 |
2002-10-24 |
Smithkline Beecham Corporation |
Antiviral pyrazolopyridine compounds
|
|
US6573287B2
(en)
|
2001-04-12 |
2003-06-03 |
Bristo-Myers Squibb Company |
2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
|
|
EP1385847B1
(en)
|
2001-04-27 |
2005-06-01 |
SmithKline Beecham Corporation |
Pyrazolo[1,5-a]pyridine derivatives
|
|
DE10121003A1
(de)
|
2001-04-28 |
2002-12-19 |
Aventis Pharma Gmbh |
Anthranilsäureamide, Verfahren zur Herstellung, ihrer Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
|
|
FR2824825B1
(fr)
|
2001-05-15 |
2005-05-06 |
Servier Lab |
Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
JP2004535433A
(ja)
|
2001-06-20 |
2004-11-25 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病治療用のジペプチジルペプチダーゼ阻害薬
|
|
CA2450475A1
(en)
|
2001-06-20 |
2003-01-03 |
Linda Brockunier |
Dipeptidyl peptidase inhibitors for the treatment of diabetes
|
|
GB0115517D0
(en)
|
2001-06-25 |
2001-08-15 |
Ferring Bv |
Novel antidiabetic agents
|
|
US6684968B2
(en)
|
2001-06-25 |
2004-02-03 |
Kennametal Inc. |
Roof bit body and insert assembly
|
|
CN1688599A
(zh)
|
2001-06-27 |
2005-10-26 |
前体生物药物股份有限公司 |
二肽基肽酶iv抑制剂的新用途
|
|
CN1990469A
(zh)
|
2001-06-27 |
2007-07-04 |
史密丝克莱恩比彻姆公司 |
作为二肽酶抑制剂的氟代吡咯烷
|
|
ES2296962T3
(es)
|
2001-06-27 |
2008-05-01 |
Smithkline Beecham Corporation |
Pirrolidinas como inhibidores de dipeptidil peptidasa.
|
|
DE60221983T2
(de)
|
2001-06-27 |
2008-05-15 |
Smithkline Beecham Corp. |
Fluorpyrrolidine als dipeptidyl-peptidase inhibitoren
|
|
DE60203010T2
(de)
|
2001-07-02 |
2005-07-07 |
Ciba Specialty Chemicals Holding Inc. |
Hochmolekulare hydroxyphenylbenzotriazolverbindungen als uv absorber für dünne filmanwendungen
|
|
EP1404675B1
(en)
|
2001-07-03 |
2008-03-12 |
Novo Nordisk A/S |
Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
|
|
ATE411021T1
(de)
|
2001-07-18 |
2008-10-15 |
Merck & Co Inc |
Überbrückte piperidinderivate als melanocortin- rezeptor-agonisten
|
|
WO2003007887A2
(en)
|
2001-07-20 |
2003-01-30 |
Merck & Co., Inc. |
Substituted imidazoles as cannabinoid receptor modulators
|
|
US6977264B2
(en)
|
2001-07-25 |
2005-12-20 |
Amgen Inc. |
Substituted piperidines and methods of use
|
|
US6915444B2
(en)
|
2001-09-12 |
2005-07-05 |
Rockwell Automation Technologies, Inc. |
Network independent safety protocol for industrial controller using data manipulation techniques
|
|
BR0212985A
(pt)
|
2001-09-24 |
2005-08-30 |
Imp College Innovations Ltd |
Uso de pyy ou de um agonista do mesmo na preparação de medicamentos para tratamento de distúrbios associados com excesso de peso
|
|
JP2005514008A
(ja)
|
2001-09-24 |
2005-05-19 |
オレゴン ヘルス アンド サイエンス ユニバーシティー |
摂食行動を改変する薬剤をスクリーニングするための、弓状核におけるニューロンの評価方法
|
|
CA2472882A1
(en)
|
2002-01-10 |
2003-07-17 |
Imperial College Innovations Ltd |
Use of pyy and glp-1, or an agonist thereof, for the modification of feeding behaviour
|
|
US20030158199A1
(en)
|
2002-01-25 |
2003-08-21 |
Kylix, B.V. |
Novel compounds for inhibition of Tie-2
|
|
US20030181468A1
(en)
|
2002-03-21 |
2003-09-25 |
Michaelides Michael R. |
Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
|
|
US20030225273A1
(en)
|
2002-03-21 |
2003-12-04 |
Michaelides Michael R. |
Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
|
|
US7560552B2
(en)
|
2002-03-21 |
2009-07-14 |
Abbott Laboratories |
Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
|
|
US7166293B2
(en)
|
2002-03-29 |
2007-01-23 |
Carlsbad Technology, Inc. |
Angiogenesis inhibitors
|
|
US6872827B2
(en)
|
2002-04-26 |
2005-03-29 |
Chembridge Research Laboratories, Inc. |
Somatostatin analogue compounds
|
|
WO2003094839A2
(en)
|
2002-05-09 |
2003-11-20 |
Cytokinetics, Inc. |
Pyrimidinone compounds, compositions and methods
|
|
GB0211019D0
(en)
|
2002-05-14 |
2002-06-26 |
Syngenta Ltd |
Novel compounds
|
|
AR037647A1
(es)
|
2002-05-29 |
2004-12-01 |
Novartis Ag |
Derivados de diarilurea utiles para el tratamiento de enfermedades dependientes de la cinasa de proteina
|
|
WO2004005283A1
(en)
|
2002-07-09 |
2004-01-15 |
Vertex Pharmaceuticals Incorporated |
Imidazoles, oxazoles and thiazoles with protein kinase inhibiting activities
|
|
ES2277142T3
(es)
|
2002-08-30 |
2007-07-01 |
Japan Tobacco Inc. |
Compuesto de dibencilamina y su uso medicinal.
|
|
JPWO2004060400A1
(ja)
|
2003-01-06 |
2006-05-11 |
那波 宏之 |
上皮成長因子受容体を分子標的とする抗精神病薬
|
|
JP4330353B2
(ja)
*
|
2003-02-21 |
2009-09-16 |
株式会社静岡カフェイン工業所 |
ピリミジン誘導体
|
|
US7183287B2
(en)
|
2003-04-03 |
2007-02-27 |
Pharmacia Corporation |
Substituted pyrimidinones
|
|
EP1633363B1
(en)
|
2003-05-08 |
2012-11-07 |
Merck Serono SA |
Pyridinyl acetonitriles
|
|
JP2005015421A
(ja)
|
2003-06-27 |
2005-01-20 |
Nissan Chem Ind Ltd |
ｏ−置換ベンゾイル化合物及びこれを有効成分とする除草剤
|
|
EP1648516A2
(en)
|
2003-08-01 |
2006-04-26 |
Wyeth Holdings Corporation |
Use of combination of an epidermal growth factor receptor kinase inhibitor and cytotoxic agents for treatment and inhibition of cancer
|
|
JP2005060299A
(ja)
|
2003-08-12 |
2005-03-10 |
Nissan Chem Ind Ltd |
置換ピリジン誘導体及びこれを有効成分とする除草剤
|
|
US7504401B2
(en)
|
2003-08-29 |
2009-03-17 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
|
JP2005104851A
(ja)
|
2003-09-29 |
2005-04-21 |
Meiji Seika Kaisha Ltd |
新規２−メチレンチオ型カルバペネム誘導体
|
|
US20050076854A1
(en)
*
|
2003-10-10 |
2005-04-14 |
Passno Richard E. |
Pet enclosure
|
|
US7582645B2
(en)
|
2003-10-10 |
2009-09-01 |
Bayer Pharmaceuticals Corporation |
Pyrimidine derivatives for treatment of hyperproliferative disorders
|
|
WO2005041888A2
(en)
|
2003-11-03 |
2005-05-12 |
Cytokinetics, Inc. |
Pyrimidin-4-one compounds, compositions and methods
|
|
JP2005194250A
(ja)
|
2004-01-09 |
2005-07-21 |
Sumitomo Chemical Takeda Agro Co Ltd |
トリアゾール化合物、その製造法および用途
|
|
SG149817A1
(en)
|
2004-01-16 |
2009-02-27 |
Wyeth Corp |
Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof
|
|
WO2005076854A2
(en)
*
|
2004-02-04 |
2005-08-25 |
Smithkline Beecham Corporation |
Pyrimidinone compounds useful as kinase inhibitors
|
|
WO2005085205A1
(ja)
|
2004-03-05 |
2005-09-15 |
Nissan Chemical Industries, Ltd. |
置換ピラゾール化合物および除草剤
|
|
KR20050091462A
(ko)
|
2004-03-12 |
2005-09-15 |
한국과학기술연구원 |
푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제
|
|
US20060035893A1
(en)
|
2004-08-07 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
|
|
US20060100226A1
(en)
|
2004-09-10 |
2006-05-11 |
Sikorski James A |
2-Thiopyrimidinones as therapeutic agents
|
|
WO2006033001A1
(en)
|
2004-09-23 |
2006-03-30 |
Pfizer Products Inc. |
Quinoline compounds
|
|
WO2006032987A1
(en)
|
2004-09-23 |
2006-03-30 |
Pfizer Products Inc. |
Indoline compounds and their use in the treatment of arteriosclerosis
|
|
WO2006040646A1
(en)
|
2004-10-14 |
2006-04-20 |
Pfizer, Inc. |
Benzimidazole or indole amides as inhibitors of pin1
|
|
DE102004055998A1
(de)
|
2004-11-19 |
2006-05-24 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Niedermolekulare Inhibitoren von Guaninnucleotid-Austauschfaktoren der Cytohesin-Familie
|
|
KR100752244B1
(ko)
*
|
2005-02-16 |
2007-08-27 |
주식회사 엠디바이오알파 |
비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 약제 조성물
|
|
KR20080002826A
(ko)
|
2005-04-14 |
2008-01-04 |
와이어쓰 |
게피티니브 내성 환자에서의 표피 성장 인자 수용체（ｅｇｆｒ） 키나제 억제제의 용도
|
|
US20070032493A1
(en)
|
2005-05-26 |
2007-02-08 |
Synta Pharmaceuticals Corp. |
Method for treating B cell regulated autoimmune disorders
|
|
WO2006128129A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating cancer
|
|
DE102005027168A1
(de)
|
2005-06-13 |
2006-12-14 |
Merck Patent Gmbh |
Tetrahydrochinoline
|
|
DE102005027169A1
(de)
|
2005-06-13 |
2006-12-14 |
Merck Patent Gmbh |
Tetrahydrochinolinderivate
|
|
US8193206B2
(en)
|
2005-06-14 |
2012-06-05 |
Taigen Biotechnology Co., Ltd. |
Pyrimidine compounds
|
|
EA015890B1
(ru)
|
2005-06-14 |
2011-12-30 |
Тайджен Байотекнолоджи Ко. Лтд. |
Производные пиримидина
|
|
GB0520164D0
(en)
|
2005-10-04 |
2005-11-09 |
Novartis Ag |
Organic compounds
|
|
US20090143396A1
(en)
|
2005-10-12 |
2009-06-04 |
Malecha James W |
Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors
|
|
US7973060B2
(en)
|
2005-10-13 |
2011-07-05 |
Crystalgenomics, Inc. |
Fab I inhibitor and process for preparing same
|
|
UY30117A1
(es)
|
2006-01-31 |
2007-06-29 |
Tanabe Seiyaku Co |
Compuesto amina trisustituido
|
|
US20070208164A1
(en)
|
2006-02-27 |
2007-09-06 |
Wyeth |
Methods of synthesizing radiolabeled 3-cyano[14C]quinolines
|
|
JP2007317714A
(ja)
|
2006-05-23 |
2007-12-06 |
Fujifilm Corp |
金属用研磨液
|
|
US7615643B2
(en)
|
2006-06-02 |
2009-11-10 |
Smithkline Beecham Corporation |
Benzimidazole thiophene compounds
|
|
US20080280891A1
(en)
|
2006-06-27 |
2008-11-13 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
|
KR20090024270A
(ko)
|
2006-06-30 |
2009-03-06 |
아스트라제네카 아베 |
암 치료에 유용한 피리미딘 유도체
|
|
KR20090029274A
(ko)
|
2006-07-21 |
2009-03-20 |
아이알엠 엘엘씨 |
Ｉｔｐｋｂ 억제제로서의 화합물 및 조성물
|
|
WO2008016811A2
(en)
|
2006-07-31 |
2008-02-07 |
Neurogen Corporation |
Aminopiperidines and realted compounds
|
|
EP2049520A4
(en)
|
2006-08-07 |
2011-01-05 |
Ironwood Pharmaceuticals Inc |
indole compounds
|
|
US8008307B2
(en)
|
2006-08-08 |
2011-08-30 |
Millennium Pharmaceuticals, Inc. |
Heteroaryl compounds useful as inhibitors of E1 activating enzymes
|
|
US20080045534A1
(en)
|
2006-08-18 |
2008-02-21 |
Valeant Pharmaceuticals North America |
Derivatives of 1,3-diamino benzene as potassium channel modulators
|
|
EP1894924A1
(en)
|
2006-08-29 |
2008-03-05 |
Phenex Pharmaceuticals AG |
Heterocyclic FXR binding compounds
|
|
WO2008057280A1
(en)
|
2006-10-27 |
2008-05-15 |
Amgen Inc. |
Multi-cyclic compounds and methods of use
|
|
EP2099774A4
(en)
|
2006-11-15 |
2010-11-24 |
Ym Biosciences Australia Pty L |
INHIBITORS OF KINASEACTIVITY
|
|
DE102006054205A1
(de)
|
2006-11-15 |
2008-05-29 |
Rheinische Friedrich-Wilhelms Universität |
Verwendung von Cytohesin-Inhibitoren zur chemischen Induktion von Langlebigkeit
|
|
TW200838526A
(en)
|
2006-12-01 |
2008-10-01 |
Astellas Pharma Inc |
Carboxylic acid derivatives
|
|
US7872018B2
(en)
|
2006-12-21 |
2011-01-18 |
Plexxikon, Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
WO2008112156A1
(en)
|
2007-03-08 |
2008-09-18 |
Altiris Therapeutics |
Chemokine receptor modulators
|
|
TW201242961A
(en)
|
2007-06-20 |
2012-11-01 |
Ironwood Pharmaceuticals Inc |
FAAH inhibitors
|
|
EP3173414A1
(en)
|
2007-07-17 |
2017-05-31 |
ACEA Biosciences Inc. |
Heterocyclic compounds and uses as anticancer agents
|
|
WO2009013545A2
(en)
|
2007-07-26 |
2009-01-29 |
Astrazeneca Ab |
Chemical compounds
|
|
CA2693495A1
(en)
|
2007-08-03 |
2009-02-12 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
TW200918521A
(en)
|
2007-08-31 |
2009-05-01 |
Astrazeneca Ab |
Heterocyclic amides and methods of use thereof
|
|
US8268849B2
(en)
|
2007-09-25 |
2012-09-18 |
Board Of Regents Of The University Of Nebraska |
Multifunctional Antioxidants and methods of use thereof
|
|
CA2702469A1
(en)
|
2007-10-19 |
2009-04-23 |
Boehringer Ingelheim International Gmbh |
Ccr10 antagonists
|
|
MX2010005356A
(es)
|
2007-11-16 |
2010-05-27 |
Schering Corp |
Derivados de indol 3-heterociclico sustituidos y metodos de uso de los mismos.
|
|
US8642660B2
(en)
*
|
2007-12-21 |
2014-02-04 |
The University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
JP2009148758A
(ja)
|
2007-12-24 |
2009-07-09 |
Em-Power Co Ltd |
噴霧熱分解方法を用いた炭素ナノチューブ用触媒製造装置及び触媒製造方法
|
|
GB0805477D0
(en)
|
2008-03-26 |
2008-04-30 |
Univ Nottingham |
Pyrimidines triazines and their use as pharmaceutical agents
|
|
CN102203074A
(zh)
|
2008-06-20 |
2011-09-28 |
麦它波莱克斯股份有限公司 |
芳基gpr119激动剂及其用途
|
|
UY31968A
(es)
|
2008-07-09 |
2010-01-29 |
Sanofi Aventis |
Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
|
|
JP2012505231A
(ja)
|
2008-10-08 |
2012-03-01 |
ブリストル−マイヤーズ スクイブ カンパニー |
アゾロピロロンメラニン凝集ホルモン受容体−１アンタゴニスト
|
|
JP2012506386A
(ja)
|
2008-10-21 |
2012-03-15 |
メタボレックス， インコーポレイテッド |
アリールｇｐｒ１２０受容体アゴニストおよびその使用
|
|
CN101723936B
(zh)
|
2008-10-27 |
2014-01-15 |
上海睿星基因技术有限公司 |
激酶抑制剂及其在药学中的用途
|
|
WO2010085246A1
(en)
|
2009-01-21 |
2010-07-29 |
Praecis Pharmaceuticals Inc |
2,4-diamino-1,3,5-triazine and 4, 6-diamino-pyrimidine derivatives and their use as aggrecanase inhibitors
|
|
CA2762680C
(en)
|
2009-05-21 |
2018-04-17 |
Chlorion Pharma, Inc. |
Methyl sulfanyl pyrmidmes useful as antiinflammatories, analgesics, and antiepileptics
|
|
MX2012002591A
(es)
|
2009-09-03 |
2012-04-02 |
Allergan Inc |
Compuestos como moduladores de tirosina cinasas.
|
|
US8906944B2
(en)
|
2009-09-03 |
2014-12-09 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
|
US20120189670A1
(en)
|
2009-09-14 |
2012-07-26 |
Kirkpatrick D Lynn |
Pharmaceutical compositions and formulations including inhibitors of the pleckstrin homology domain and methods for using same
|
|
WO2011066137A1
(en)
|
2009-11-24 |
2011-06-03 |
Schering Corporation |
Substituted biaryl derivatives and methods of use thereof
|
|
FR2953145B1
(fr)
|
2009-11-30 |
2013-07-19 |
Inst Francais Du Petrole |
Solution absorbante contenant un inhibiteur de degradation derive de la pyrimidine ou de la triazine et procede d'absorption de composes acides contenus dans un effluent gazeux
|
|
WO2011082098A1
(en)
|
2009-12-30 |
2011-07-07 |
The Rockefeller University |
Lysine and arginine methyltransferase inhibitors for treating cancer
|
|
MY160036A
(en)
|
2010-01-27 |
2017-02-15 |
Boehringer Ingelheim Int |
Pyrazole compounds as crth2 antagonists
|
|
SG185515A1
(en)
|
2010-05-13 |
2012-12-28 |
Amgen Inc |
Nitrogen heterocyclic compounds useful as pde10 inhibitors
|
|
JP2013526524A
(ja)
|
2010-05-13 |
2013-06-24 |
アムジエン・インコーポレーテツド |
Ｐｄｅ１０阻害剤としてのアリールおよびヘテロアリール窒素ヘテロ環式化合物
|
|
US8497265B2
(en)
|
2010-05-13 |
2013-07-30 |
Amgen Inc. |
Heteroaryloxyheterocyclyl compounds as PDE10 inhibitors
|
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
|
MX2012014996A
(es)
|
2010-07-01 |
2013-03-21 |
Amgen Inc |
Compuestos heterociclicos y su uso como inhibidores de la actividad pi3k.
|
|
EP2588467A1
(en)
|
2010-07-01 |
2013-05-08 |
Amgen Inc. |
Heterocyclic compounds and their use as inhibitors of pi3k activity
|
|
US20130096134A1
(en)
|
2010-07-02 |
2013-04-18 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
|
JP2013230986A
(ja)
|
2010-08-25 |
2013-11-14 |
Kyorin Pharmaceutical Co Ltd |
新規ヒダントイン誘導体及びそれらを有効成分とする医薬
|
|
WO2012068343A1
(en)
|
2010-11-17 |
2012-05-24 |
Amgen Inc. |
Quinoline derivatives as pik3 inhibitors
|
|
US20120184572A1
(en)
|
2011-01-13 |
2012-07-19 |
Metabolex, Inc. |
Aryl gpr119 agonists and uses thereof
|
|
CN102617480A
(zh)
|
2011-01-30 |
2012-08-01 |
中国人民解放军军事医学科学院毒物药物研究所 |
二-(杂)芳基取代的叔胺类化合物及其制备方法和抗肿瘤应用
|
|
UY33929A
(es)
|
2011-03-04 |
2012-10-31 |
Novartis Ag |
Compuestos de ciclohexilo tetrasustituido como inhibidores de quinasas
|
|
MY177070A
(en)
|
2011-03-15 |
2020-09-04 |
Astellas Pharma Inc |
Guanidine compound
|
|
WO2012126181A1
(en)
|
2011-03-24 |
2012-09-27 |
Ying Luo |
Use of kinase inhibitors in preventing and treating inflammatory disorder
|
|
EP2709609B1
(en)
|
2011-05-17 |
2017-10-04 |
Shionogi & Co., Ltd. |
Heterocyclic compounds
|
|
WO2012166415A1
(en)
|
2011-05-27 |
2012-12-06 |
Amira Pharmaceuticals, Inc. |
Heterocyclic autotaxin inhibitors and uses thereof
|
|
GB201111705D0
(en)
|
2011-07-07 |
2011-08-24 |
Takeda Pharmaceutical |
Compounds and their use
|
|
DE102011088009A1
(de)
|
2011-12-08 |
2013-06-13 |
Henkel Ag & Co. Kgaa |
Theophyllinderivate zur Repigmentierung von keratinhaltigen Fasern
|
|
JP6353788B2
(ja)
|
2012-01-13 |
2018-07-04 |
エイシア バイオサイエンシーズ インコーポレイテッド |
抗がん剤としての複素環式化合物およびその使用
|
|
CN104395458A
(zh)
|
2012-04-11 |
2015-03-04 |
赛特凯恩蒂克公司 |
改善对骨骼肌疲劳的抵抗力
|
|
US8633182B2
(en)
|
2012-05-30 |
2014-01-21 |
Boehringer Ingelheim International Gmbh |
Indanyloxyphenylcyclopropanecarboxylic acids
|
|
US9013997B2
(en)
|
2012-06-01 |
2015-04-21 |
Broadcom Corporation |
System for performing distributed data cut-through
|
|
CN104870438A
(zh)
*
|
2012-06-07 |
2015-08-26 |
佐治亚州立大学研究基金会公司 |
Seca抑制剂以及其制备和使用方法
|
|
WO2014026039A2
(en)
|
2012-08-09 |
2014-02-13 |
Neuropore Therapies, Inc. |
Aryl-and heteroaryl-substituted benzene derivatives as modulators of pi3-kinase signalling pathways
|
|
WO2014031928A2
(en)
|
2012-08-24 |
2014-02-27 |
Philip Jones |
Heterocyclic modulators of hif activity for treatment of disease
|
|
KR101667799B1
(ko)
|
2012-09-07 |
2016-10-20 |
삼성디스플레이 주식회사 |
유기금속 화합물 및 이를 포함한 유기 발광 소자
|
|
FR2996129B1
(fr)
|
2012-09-28 |
2014-12-19 |
Oreal |
Procede de coloration capillaire mettant en oeuvre au moins un derive d'heterocycle azote, un sel de manganese ou de zinc, du peroxyde d'hydrogene et du (bi)carbonate
|
|
JO3470B1
(ar)
|
2012-10-08 |
2020-07-05 |
Merck Sharp & Dohme |
مشتقات 5- فينوكسي-3h-بيريميدين-4-أون واستخدامها كمثبطات ناسخ عكسي ل hiv
|
|
US10035790B2
(en)
|
2012-10-19 |
2018-07-31 |
Exelixis, Inc. |
RORγ modulators
|
|
US20140148484A1
(en)
|
2012-11-23 |
2014-05-29 |
Boehringer Ingelheim International Gmbh |
Pyrazole compounds for treating hairloss
|
|
US20160002247A1
(en)
|
2013-03-01 |
2016-01-07 |
The University Of Tokyo |
8-substituted imidazopyrimidinone derivative having autotaxin inhibitory activity
|
|
CN104059082B
(zh)
|
2013-03-21 |
2016-08-03 |
苏州迈泰生物技术有限公司 |
硝基咪唑杂环类化合物及其在制备治疗结核病药物中的应用
|
|
CN105339359B
(zh)
|
2013-04-26 |
2018-02-16 |
住友化学株式会社 |
四唑啉酮化合物及其用途
|
|
WO2014181287A1
(en)
|
2013-05-09 |
2014-11-13 |
Piramal Enterprises Limited |
Heterocyclyl compounds and uses thereof
|
|
US20140350256A1
(en)
|
2013-05-21 |
2014-11-27 |
University Of Southern Denmark |
Iron and manganese complexes comprising hexadentate monocarboxylato-containing ligands and their use for the catalysis of oxidation reactions
|
|
US9751832B2
(en)
|
2013-07-30 |
2017-09-05 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Selective histone deactylase 6 inhibitors
|
|
EP3057954A2
(en)
|
2013-10-18 |
2016-08-24 |
Syros Pharmaceuticals, Inc. |
Heteromaromatic compounds useful for the treatment of proliferative diseases
|
|
RU2019131017A
(ru)
|
2013-10-21 |
2019-11-25 |
Мерк Патент Гмбх |
Соединения гетероарила в качестве ингибиторов btk и их применение
|
|
WO2015069287A1
(en)
|
2013-11-08 |
2015-05-14 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
|
US9340504B2
(en)
|
2013-11-21 |
2016-05-17 |
Purdue Pharma L.P. |
Pyridine and piperidine derivatives as novel sodium channel blockers
|
|
CN105017085B
(zh)
*
|
2014-04-28 |
2018-06-29 |
中国科学院上海药物研究所 |
一类kcnq钾通道激动剂、其制备方法和用途
|
|
MX389591B
(es)
|
2014-08-29 |
2025-03-20 |
Tes Pharma S R L |
INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA
|