JP2017514856A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017514856A5 JP2017514856A5 JP2016566651A JP2016566651A JP2017514856A5 JP 2017514856 A5 JP2017514856 A5 JP 2017514856A5 JP 2016566651 A JP2016566651 A JP 2016566651A JP 2016566651 A JP2016566651 A JP 2016566651A JP 2017514856 A5 JP2017514856 A5 JP 2017514856A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- alkyl
- alkoxy
- independently
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C[C@@](C1)C2CC1*C2 Chemical compound C[C@@](C1)C2CC1*C2 0.000 description 9
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461989651P | 2014-05-07 | 2014-05-07 | |
| US61/989,651 | 2014-05-07 | ||
| PCT/US2015/029409 WO2015171722A1 (en) | 2014-05-07 | 2015-05-06 | Pyrrolidine gpr40 modulators for the treatment of diseases such as diabetes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017514856A JP2017514856A (ja) | 2017-06-08 |
| JP2017514856A5 true JP2017514856A5 (enExample) | 2018-04-19 |
| JP6483156B2 JP6483156B2 (ja) | 2019-03-13 |
Family
ID=53181359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016566651A Active JP6483156B2 (ja) | 2014-05-07 | 2015-05-06 | 糖尿病などの疾患の治療用のピロリジンｇｐｒ４０モジュレータ |
Country Status (33)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015256038B2 (en) * | 2014-05-07 | 2019-07-11 | Bristol-Myers Squibb Company | Pyrrolidine GPR40 modulators for the treatment of diseases such as diabetes |
| MA39427B1 (fr) * | 2014-05-07 | 2018-09-28 | Bristol Myers Squibb Co | Composés pyrrolidine modulateurs de gpr40 pour le traitement de maladies telles que le diabète |
| JP7086942B2 (ja) | 2016-09-12 | 2022-06-20 | インテグラル ヘルス， インコーポレイテッド | Ｇｐｒ１２０モジュレーターとして有用な単環式化合物 |
| CN110121343B (zh) | 2016-09-12 | 2023-11-03 | 整体健康 | 用作gpr120调节剂的双环化合物 |
| US11186565B2 (en) | 2017-03-31 | 2021-11-30 | Takeda Pharmaceutical Company Limited | Aromatic compound |
| CN110538327B (zh) * | 2017-08-21 | 2021-08-03 | 武汉大学 | Gpr31抑制剂在制备治疗脂肪代谢异常及相关疾病的药物中的应用 |
| EP4227302A1 (en) | 2018-02-13 | 2023-08-16 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| US10899735B2 (en) | 2018-04-19 | 2021-01-26 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| UA126421C2 (uk) | 2018-07-13 | 2022-09-28 | Гіліад Сайєнсіз, Інк. | Інгібітори pd-1/pd-l1 |
| AU2019366355B2 (en) | 2018-10-24 | 2022-10-13 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| AU2022291768A1 (en) | 2021-06-16 | 2023-11-30 | Celgene Corporation | Azetidinyl compounds comprising a carboxylic acid group for the treatment of neurodegenerative diseases |
| CN116283699B (zh) * | 2023-03-02 | 2025-02-11 | 遵义医科大学 | 一种合成氟烷基取代的吡咯烷的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5614492A (en) | 1986-05-05 | 1997-03-25 | The General Hospital Corporation | Insulinotropic hormone GLP-1 (7-36) and uses thereof |
| WO2011044073A1 (en) * | 2009-10-06 | 2011-04-14 | Bristol-Myers Squibb Company | Pyrrolidine gpr40 modulators |
| US7939569B1 (en) * | 2009-12-01 | 2011-05-10 | Hoffmann-La Roche Inc. | Aniline analogs as glycogen synthase activators |
| GB2498976A (en) * | 2012-02-01 | 2013-08-07 | Prosidion Ltd | GPR119 agonists useful in the treatment of type II diabetes |
| US9120798B2 (en) | 2012-08-01 | 2015-09-01 | Bristol-Myers Squibb Company | Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of P2Y1 receptor |
| CN104812748B (zh) * | 2012-11-16 | 2017-10-24 | 百时美施贵宝公司 | 二氢吡唑gpr40调节剂 |
| SG11201503556PA (en) | 2012-11-16 | 2015-06-29 | Bristol Myers Squibb Co | Dihydropyrazole gpr40 modulators |
| KR20150082615A (ko) * | 2012-11-16 | 2015-07-15 | 브리스톨-마이어스 스큅 컴퍼니 | 피롤리딘 gpr40 조절제 |
| MX2015005720A (es) | 2012-11-16 | 2015-09-08 | Bristol Myers Squibb Co | Moduladores de dihidropirazol de receptor acoplado a la proteina g (gpr40). |
| WO2015171757A1 (en) | 2014-05-07 | 2015-11-12 | Bristol-Myers Squibb Company | Pyrrolidine gpr40 modulators |
| MA39427B1 (fr) * | 2014-05-07 | 2018-09-28 | Bristol Myers Squibb Co | Composés pyrrolidine modulateurs de gpr40 pour le traitement de maladies telles que le diabète |
| HRP20191667T1 (hr) | 2014-05-07 | 2019-12-13 | Croma Pharma Ges M B H | Vodenasta oftalmološka otopina i postupak tretmana sindroma suhog oka |
-
2015
- 2015-05-06 MA MA39427A patent/MA39427B1/fr unknown
- 2015-05-06 TW TW104114493A patent/TWI659951B/zh active
- 2015-05-06 BR BR112016024936A patent/BR112016024936A2/pt not_active Application Discontinuation
- 2015-05-06 HU HUE15723095A patent/HUE039288T2/hu unknown
- 2015-05-06 SI SI201530232T patent/SI3140296T1/en unknown
- 2015-05-06 HR HRP20180641TT patent/HRP20180641T1/hr unknown
- 2015-05-06 WO PCT/US2015/029409 patent/WO2015171722A1/en not_active Ceased
- 2015-05-06 MX MX2016013801A patent/MX378160B/es unknown
- 2015-05-06 PE PE2016002178A patent/PE20161363A1/es unknown
- 2015-05-06 TN TN2016000444A patent/TN2016000444A1/en unknown
- 2015-05-06 NZ NZ727146A patent/NZ727146A/en unknown
- 2015-05-06 PL PL15723095T patent/PL3140296T3/pl unknown
- 2015-05-06 CN CN201580022579.4A patent/CN106458976B/zh active Active
- 2015-05-06 ES ES15723095.4T patent/ES2674531T3/es active Active
- 2015-05-06 KR KR1020167033863A patent/KR102336370B1/ko active Active
- 2015-05-06 CA CA2948161A patent/CA2948161C/en active Active
- 2015-05-06 AU AU2015256120A patent/AU2015256120B2/en active Active
- 2015-05-06 EA EA201692037A patent/EA033250B1/ru not_active IP Right Cessation
- 2015-05-06 US US14/705,524 patent/US9873679B2/en active Active
- 2015-05-06 RS RS20180504A patent/RS57170B1/sr unknown
- 2015-05-06 EP EP15723095.4A patent/EP3140296B1/en active Active
- 2015-05-06 SG SG11201609170UA patent/SG11201609170UA/en unknown
- 2015-05-06 AR ARP150101379A patent/AR100328A1/es unknown
- 2015-05-06 JP JP2016566651A patent/JP6483156B2/ja active Active
- 2015-05-06 DK DK15723095.4T patent/DK3140296T3/en active
- 2015-05-06 MY MYPI2016704054A patent/MY181959A/en unknown
- 2015-05-06 PT PT157230954T patent/PT3140296T/pt unknown
- 2015-05-06 SM SM20180342T patent/SMT201800342T1/it unknown
- 2015-05-06 TR TR2018/09633T patent/TR201809633T4/tr unknown
-
2016
- 2016-10-12 PH PH12016502034A patent/PH12016502034B1/en unknown
- 2016-11-01 IL IL248668A patent/IL248668B/en active IP Right Grant
- 2016-11-07 CL CL2016002809A patent/CL2016002809A1/es unknown
-
2017
- 2017-12-13 US US15/840,198 patent/US20180099949A1/en not_active Abandoned
-
2018
- 2018-05-23 CY CY20181100547T patent/CY1120340T1/el unknown
- 2018-12-06 US US16/211,848 patent/US10717725B2/en active Active
-
2020
- 2020-06-08 US US16/895,058 patent/US20200299267A1/en not_active Abandoned