JP2017514856A5 - - Google Patents
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- JP2017514856A5 JP2017514856A5 JP2016566651A JP2016566651A JP2017514856A5 JP 2017514856 A5 JP2017514856 A5 JP 2017514856A5 JP 2016566651 A JP2016566651 A JP 2016566651A JP 2016566651 A JP2016566651 A JP 2016566651A JP 2017514856 A5 JP2017514856 A5 JP 2017514856A5
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- 0 C[C@@](C1)C2CC1*C2 Chemical compound C[C@@](C1)C2CC1*C2 0.000 description 9
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461989651P | 2014-05-07 | 2014-05-07 | |
| US61/989,651 | 2014-05-07 | ||
| PCT/US2015/029409 WO2015171722A1 (en) | 2014-05-07 | 2015-05-06 | Pyrrolidine gpr40 modulators for the treatment of diseases such as diabetes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017514856A JP2017514856A (ja) | 2017-06-08 |
| JP2017514856A5 true JP2017514856A5 (enExample) | 2018-04-19 |
| JP6483156B2 JP6483156B2 (ja) | 2019-03-13 |
Family
ID=53181359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016566651A Active JP6483156B2 (ja) | 2014-05-07 | 2015-05-06 | 糖尿病などの疾患の治療用のピロリジンｇｐｒ４０モジュレータ |
Country Status (33)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR201809633T4 (tr) * | 2014-05-07 | 2018-07-23 | Bristol Myers Squibb Co | Diyabet gibi hastalıkların tedavisine yönelik pirolidin GPR40 modülatörleri. |
| KR20170002543A (ko) * | 2014-05-07 | 2017-01-06 | 브리스톨-마이어스 스큅 컴퍼니 | 당뇨병과 같은 질환의 치료를 위한 피롤리딘 gpr40 조정제 |
| EP3509588B1 (en) | 2016-09-12 | 2023-06-07 | Integral Health,Inc. | Bicyclic compounds useful as gpr120 modulators |
| KR102537985B1 (ko) | 2016-09-12 | 2023-05-30 | 인테그랄 헬스 인코퍼레이티드 | Gpr120 조정제로서 유용한 단환형 화합물 |
| WO2018181847A1 (ja) * | 2017-03-31 | 2018-10-04 | 武田薬品工業株式会社 | 芳香環化合物 |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| CN107362365B (zh) * | 2017-08-21 | 2020-01-07 | 武汉大风生物科技有限公司 | Gpr31抑制剂在制药中的应用 |
| KR102708681B1 (ko) | 2018-02-13 | 2024-09-26 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| EP4600247A3 (en) | 2018-04-19 | 2025-11-19 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| UA126421C2 (uk) | 2018-07-13 | 2022-09-28 | Гіліад Сайєнсіз, Інк. | Інгібітори pd-1/pd-l1 |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| CA3217423A1 (en) | 2021-06-16 | 2022-12-22 | Jeffrey M. Schkeryantz | Azetidinyl compounds comprising a carboxylic acid group for the treatment of neurodegenerative diseases |
| CN116283699B (zh) * | 2023-03-02 | 2025-02-11 | 遵义医科大学 | 一种合成氟烷基取代的吡咯烷的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5614492A (en) | 1986-05-05 | 1997-03-25 | The General Hospital Corporation | Insulinotropic hormone GLP-1 (7-36) and uses thereof |
| CN102639495A (zh) * | 2009-10-06 | 2012-08-15 | 百时美施贵宝公司 | 吡咯烷gpr40调节剂 |
| US7939569B1 (en) * | 2009-12-01 | 2011-05-10 | Hoffmann-La Roche Inc. | Aniline analogs as glycogen synthase activators |
| GB2498976A (en) * | 2012-02-01 | 2013-08-07 | Prosidion Ltd | GPR119 agonists useful in the treatment of type II diabetes |
| WO2014022253A1 (en) | 2012-08-01 | 2014-02-06 | Bristol-Myers Squibb Company | Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of p2y1 receptor |
| KR20150082618A (ko) | 2012-11-16 | 2015-07-15 | 브리스톨-마이어스 스큅 컴퍼니 | 디히드로피라졸 gpr40 조절제 |
| US9656963B2 (en) | 2012-11-16 | 2017-05-23 | Bristol-Myers Squibb Company | Dihydropyrazole GPR40 modulators |
| HUE032401T2 (en) | 2012-11-16 | 2017-09-28 | Bristol Myers Squibb Co | Dihydropyrazole GPR40 modulators |
| BR112015010649A2 (pt) * | 2012-11-16 | 2017-07-11 | Bristol Myers Squibb Co | moduladores de gpr40 à base de pirrolidina |
| TR201809633T4 (tr) * | 2014-05-07 | 2018-07-23 | Bristol Myers Squibb Co | Diyabet gibi hastalıkların tedavisine yönelik pirolidin GPR40 modülatörleri. |
| WO2015171757A1 (en) | 2014-05-07 | 2015-11-12 | Bristol-Myers Squibb Company | Pyrrolidine gpr40 modulators |
| WO2015169728A1 (en) | 2014-05-07 | 2015-11-12 | Croma-Pharma Gesellschaft M.B.H. | Aqueous ophthalmic solution and method for treating dry eye syndrome |
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2015
- 2015-05-06 TR TR2018/09633T patent/TR201809633T4/tr unknown
- 2015-05-06 KR KR1020167033863A patent/KR102336370B1/ko active Active
- 2015-05-06 CA CA2948161A patent/CA2948161C/en active Active
- 2015-05-06 PL PL15723095T patent/PL3140296T3/pl unknown
- 2015-05-06 CN CN201580022579.4A patent/CN106458976B/zh active Active
- 2015-05-06 MY MYPI2016704054A patent/MY181959A/en unknown
- 2015-05-06 JP JP2016566651A patent/JP6483156B2/ja active Active
- 2015-05-06 ES ES15723095.4T patent/ES2674531T3/es active Active
- 2015-05-06 RS RS20180504A patent/RS57170B1/sr unknown
- 2015-05-06 PT PT157230954T patent/PT3140296T/pt unknown
- 2015-05-06 AU AU2015256120A patent/AU2015256120B2/en active Active
- 2015-05-06 DK DK15723095.4T patent/DK3140296T3/en active
- 2015-05-06 TN TN2016000444A patent/TN2016000444A1/en unknown
- 2015-05-06 BR BR112016024936A patent/BR112016024936A2/pt not_active Application Discontinuation
- 2015-05-06 SM SM20180342T patent/SMT201800342T1/it unknown
- 2015-05-06 WO PCT/US2015/029409 patent/WO2015171722A1/en not_active Ceased
- 2015-05-06 MX MX2016013801A patent/MX378160B/es unknown
- 2015-05-06 HU HUE15723095A patent/HUE039288T2/hu unknown
- 2015-05-06 SI SI201530232T patent/SI3140296T1/en unknown
- 2015-05-06 HR HRP20180641TT patent/HRP20180641T1/hr unknown
- 2015-05-06 SG SG11201609170UA patent/SG11201609170UA/en unknown
- 2015-05-06 PE PE2016002178A patent/PE20161363A1/es unknown
- 2015-05-06 US US14/705,524 patent/US9873679B2/en active Active
- 2015-05-06 EP EP15723095.4A patent/EP3140296B1/en active Active
- 2015-05-06 NZ NZ727146A patent/NZ727146A/en unknown
- 2015-05-06 MA MA39427A patent/MA39427B1/fr unknown
- 2015-05-06 AR ARP150101379A patent/AR100328A1/es unknown
- 2015-05-06 EA EA201692037A patent/EA033250B1/ru not_active IP Right Cessation
- 2015-05-06 TW TW104114493A patent/TWI659951B/zh active
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2016
- 2016-10-12 PH PH12016502034A patent/PH12016502034B1/en unknown
- 2016-11-01 IL IL248668A patent/IL248668B/en active IP Right Grant
- 2016-11-07 CL CL2016002809A patent/CL2016002809A1/es unknown
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2017
- 2017-12-13 US US15/840,198 patent/US20180099949A1/en not_active Abandoned
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2018
- 2018-05-23 CY CY20181100547T patent/CY1120340T1/el unknown
- 2018-12-06 US US16/211,848 patent/US10717725B2/en active Active
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2020
- 2020-06-08 US US16/895,058 patent/US20200299267A1/en not_active Abandoned