AU2002227170A1 - Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives - Google Patents

Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives

Info

Publication number
AU2002227170A1
AU2002227170A1 AU2002227170A AU2717002A AU2002227170A1 AU 2002227170 A1 AU2002227170 A1 AU 2002227170A1 AU 2002227170 A AU2002227170 A AU 2002227170A AU 2717002 A AU2717002 A AU 2717002A AU 2002227170 A1 AU2002227170 A1 AU 2002227170A1
Authority
AU
Australia
Prior art keywords
diazepino
indoles
cycloalkyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002227170A
Inventor
Joan Eileen Sabalski
Annmarie Louise Sabb
Robert Lewis Vogel
Gregory Scott Welmaker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2002227170A1 publication Critical patent/AU2002227170A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
AU2002227170A 2000-11-03 2001-11-01 Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives Abandoned AU2002227170A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US24560200P 2000-11-03 2000-11-03
US24559800P 2000-11-03 2000-11-03
US24559900P 2000-11-03 2000-11-03
US60/245,602 2000-11-03
US60/245,598 2000-11-03
US60/245,599 2000-11-03
PCT/US2001/046084 WO2002036596A2 (en) 2000-11-03 2001-11-01 CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES

Publications (1)

Publication Number Publication Date
AU2002227170A1 true AU2002227170A1 (en) 2002-05-15

Family

ID=27399866

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002227170A Abandoned AU2002227170A1 (en) 2000-11-03 2001-11-01 Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives

Country Status (2)

Country Link
AU (1) AU2002227170A1 (en)
WO (1) WO2002036596A2 (en)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR031202A1 (en) 2000-11-03 2003-09-10 Wyeth Corp CYCLOPENTA (B) (1,4) DIAZEPINO (6,7,1-HI) INDOLES AND DERIVATIVES
AR031199A1 (en) 2000-11-03 2003-09-10 Wyeth Corp CICLOHEPTA / B // 1,4 / DIACEPINO / 6,7,1-HI / INDOLES AND DERIVATIVES
AR031200A1 (en) 2000-11-03 2003-09-10 Wyeth Corp CYCLOCATE [B] [1,4] DIAZEPINO [6,7,1-HI] INDOLES AND DERIVATIVES
TWI312781B (en) 2002-04-25 2009-08-01 [1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
TW200307540A (en) 2002-04-25 2003-12-16 Wyeth Corp [1, 4]Diazocino[7, 8, 1-hi] indole derivatives as antipsychotic and antiobesity agents
TW200307682A (en) 2002-04-25 2003-12-16 Wyeth Corp 1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
WO2004000830A1 (en) 2002-06-19 2003-12-31 Biovitrum Ab Novel compounds, their use and preparation
US7105526B2 (en) 2002-06-28 2006-09-12 Banyu Pharmaceuticals Co., Ltd. Benzimidazole derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP4765627B2 (en) 2003-09-22 2011-09-07 Ｍｓｄ株式会社 Novel piperidine derivatives
PL1980149T3 (en) 2004-04-01 2012-08-31 Basf Agrochemical Products Bv Synergistically acting herbicidal mixtures
EP1734963A4 (en) 2004-04-02 2008-06-18 Merck & Co Inc Method of treating men with metabolic and anthropometric disorders
EP1792629A4 (en) 2004-08-25 2010-08-25 Takeda Pharmaceutical Preventives/remedies for stress urinary incontinence and method of screening the same
EP2127676A3 (en) 2004-11-01 2013-09-04 Amylin Pharmaceuticals, LLC Treatment of obesity and related disorders
GT200500317A (en) 2004-11-05 2006-10-27 PROCESS TO PREPARE QUINOLINE COMPOUNDS AND PRODUCTS OBTAINED FROM THEM
US7737155B2 (en) 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
CA2609388C (en) 2005-05-30 2013-08-06 Banyu Pharmaceutical Co., Ltd. Novel piperidine derivative
AR054849A1 (en) 2005-07-26 2007-07-18 Wyeth Corp DIAZEPINOQUINOLINAS, SYNTHESIS OF THE SAME, AND INTERMEDIARIES TO OBTAIN THEM
JPWO2007018248A1 (en) 2005-08-10 2009-02-19 萬有製薬株式会社 Pyridone compounds
EP1922336B1 (en) 2005-08-11 2012-11-21 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
BRPI0614649A2 (en) 2005-08-11 2011-04-12 Amylin Pharmaceuticals Inc hybrid polypeptides with selectable properties
AU2006282260A1 (en) 2005-08-24 2007-03-01 Msd K.K. Phenylpyridone derivative
CA2621470A1 (en) 2005-09-07 2007-03-15 Banyu Pharmaceutical Co., Ltd. Bicyclic aromatic substituted pyridone derivative
AU2006297443B2 (en) 2005-09-29 2010-08-12 Merck Sharp & Dohme Corp. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
US20080255084A1 (en) 2005-10-21 2008-10-16 Randy Lee Webb Combination of Organic Compounds
EP1944301A4 (en) 2005-10-27 2012-01-04 Msd Kk Novel benzoxathiin derivative
MY146564A (en) 2005-11-10 2012-08-30 Msd Kk Aza-substituted spiro derivatives
CL2007000773A1 (en) * 2006-03-24 2008-01-25 Wyeth Corp Use of compounds derived from condensed diazepine for the treatment of a cognitive disorder such as add or adhd; or its use to treat spm or pmdd.
RU2008140136A (en) * 2006-03-24 2010-04-27 Вайет (Us) NEW THERAPEUTIC COMBINATIONS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS
US8158617B2 (en) 2006-05-16 2012-04-17 Takeda Pharmaceutical Company Limited Fused heterocyclic compound and use thereof
US8173629B2 (en) 2006-09-22 2012-05-08 Merck Sharp & Dohme Corp. Method of treatment using fatty acid synthesis inhibitors
AU2007301126A1 (en) 2006-09-28 2008-04-03 Banyu Pharmaceutical Co., Ltd. Diaryl ketimine derivative
NZ578891A (en) 2007-01-16 2012-03-30 Ipintl Llc Novel composition for treating metabolic syndrome
EP2145884B1 (en) 2007-04-02 2014-08-06 Msd K.K. Indoledione derivative
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CN101772513B (en) 2007-06-04 2013-11-13 协同医药品公司 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP5520051B2 (en) 2007-11-15 2014-06-11 武田薬品工業株式会社 Condensed pyridine derivatives and uses thereof
WO2009110510A1 (en) 2008-03-06 2009-09-11 萬有製薬株式会社 Alkylaminopyridine derivative
JPWO2009119726A1 (en) 2008-03-28 2011-07-28 Ｍｓｄ株式会社 Diarylmethylamide derivatives having melanin-concentrating hormone receptor antagonistic activity
CA2666036C (en) 2008-05-16 2017-09-12 Chien-Hung Chen Novel compositions and methods for treating hyperproliferative diseases
ES2522968T3 (en) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JPWO2009154132A1 (en) 2008-06-19 2011-12-01 Ｍｓｄ株式会社 Spirodiamine-diarylketoxime derivatives
JP2011528375A (en) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders
CA2731358A1 (en) 2008-07-30 2010-02-04 Banyu Pharmaceutical Co., Ltd. 5/5-or 5/6-membered condensed ring cycloalkylamine derivative
MX2011004258A (en) 2008-10-22 2011-06-01 Merck Sharp & Dohme Novel cyclic benzimidazole derivatives useful anti-diabetic agents.
PE20110852A1 (en) 2008-10-30 2011-11-25 Merck Sharp & Dohme ISONICOTINAMIDE OREXIN RECEPTOR ANTAGONISTS
CN102271509A (en) 2008-10-31 2011-12-07 默沙东公司 Novel cyclic benzimidazole derivatives useful anti-diabetic agents
EP2379562A1 (en) 2008-12-16 2011-10-26 Schering Corporation Bicyclic pyranone derivatives as nicotinic acid receptor agonists
US20110245209A1 (en) 2008-12-16 2011-10-06 Schering Corporation Pyridopyrimidine derivatives and methods of use thereof
EP2510949A4 (en) 2009-12-11 2013-11-13 Astellas Pharma Inc Therapeutic agent for fibromyalgia
JP2013520502A (en) 2010-02-25 2013-06-06 メルク・シャープ・エンド・ドーム・コーポレイション Novel cyclic benzimidazole derivatives that are useful anti-diabetic drugs
US20130267500A1 (en) 2010-09-01 2013-10-10 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
BR122021002201A8 (en) 2011-02-25 2023-04-11 Merck Sharp & Dohme COMPOUND, COMPOSITION, USE OF A COMPOUND, AND METHOD OF TREATMENT OF A DISORDER, CONDITION OR DISEASE
CA2828346C (en) 2011-03-01 2021-01-26 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
AR088352A1 (en) 2011-10-19 2014-05-28 Merck Sharp & Dohme ANTAGONISTS OF THE RECEIVER OF 2-PIRIDILOXI-4-NITRILE OREXINE
CN102657198B (en) * 2012-05-08 2014-03-19 陕西上格之路生物科学有限公司 Sterilization and production-increase composition containing phethalanilic acid
MX2015001500A (en) 2012-08-02 2015-04-08 Merck Sharp & Dohme Antidiabetic tricyclic compounds.
AU2013314279B2 (en) * 2012-09-14 2017-11-02 AbbVie Deutschland GmbH & Co. KG Tricyclic quinoline and quinoxaline derivatives
WO2014139388A1 (en) 2013-03-14 2014-09-18 Merck Sharp & Dohme Corp. Novel indole derivatives useful as anti-diabetic agents
JP2016514671A (en) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists and uses thereof
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
CN103204858A (en) * 2013-03-20 2013-07-17 广州科瑞生物技术有限公司 Novel chirality antianxiety medicine prepared on basis of tartaric acid resolution and composition technique
WO2014197720A2 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
DK3186242T3 (en) 2014-08-29 2021-12-20 Tes Pharma S R L ALFA-AMINO-BETA-CARBOXYMUCONSIDE-SEMIALDEHYDE-DECARBOXYLASE INHIBITORS
WO2016176177A1 (en) * 2015-04-27 2016-11-03 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
EP3526199B1 (en) 2016-10-14 2022-04-13 Tes Pharma S.r.l. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
JPWO2019131902A1 (en) 2017-12-27 2020-12-10 武田薬品工業株式会社 Remedies for stress urinary incontinence and fecal incontinence
KR20210111248A (en) 2018-11-20 2021-09-10 테스 파마 에스.알.엘. Inhibitors of α-amino-β-carboxymuconic acid semialdehyde decarboxylase
EP3924058A1 (en) 2019-02-13 2021-12-22 Merck Sharp & Dohme Corp. 5-alkyl pyrrolidine orexin receptor agonists
WO2021026047A1 (en) 2019-08-08 2021-02-11 Merck Sharp & Dohme Corp. Heteroaryl pyrrolidine and piperidine orexin receptor agonists
MX2023001840A (en) 2020-08-18 2023-03-13 Merck Sharp & Dohme Llc Bicycloheptane pyrrolidine orexin receptor agonists.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914250A (en) * 1974-08-01 1975-10-21 American Home Prod 1,4-Diazepino{8 6,5,4-jk{9 carbazoles

Also Published As

Publication number Publication date
WO2002036596A2 (en) 2002-05-10
WO2002036596A3 (en) 2002-10-24

Similar Documents

Publication Publication Date Title
AU2002227170A1 (en) Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives
AU2001292898A1 (en) Substituted azepino[4,5b)indole derivatives
AU2647597A (en) Oxindole derivatives
AU1573201A (en) Indole-3-carbinol (i3c) derivatives
AU7738198A (en) Aminopyrazole derivatives
AU2845999A (en) Cushioned earphones
AU3464599A (en) Aminoalkyl substituted 9h-pyridino(2,3-b)indole and 9h-pyrimidino(4,5-b)indole derivatives
AU1648300A (en) Seat
AU2882801A (en) Azepine derivatives
AU7947000A (en) Tricyclic fused-imidazole derivatives
AU4136197A (en) Pyrrolocarbazole derivatives
AU7730500A (en) Biomolecular attachment sites on microelectronic arrays and methods thereof
AU2001271876A1 (en) Azepino(4,5-b)pyrano(3,2-e)indoles
AU2610299A (en) Hydrazone derivatives
AU2001234178A1 (en) Modified bdnf
AU2001292241A1 (en) Benzodiazepine derivative
AUPO678897A0 (en) Foldable chair
AU2002364590A1 (en) Hydroxylated indole derivatives and uses thereof
AU1140199A (en) Foldable bicycle
AU1304801A (en) Tricyclic azaindolizine derivatives having an SPLA2- inhibiting effect
AU1698899A (en) N-acetylserotonin derivatives and uses thereof
AU4485400A (en) Synthetic indolocarbazole regioisomers and uses thereof
MXPA03004687A (en) Indole and dihydroindole derivatives.
AU2002212341A1 (en) Hexahydro-4-oxoazepino(3,2,1-hi)indoles
AU5064600A (en) Stand-only/seat combination