JP2016510326A5 - - Google Patents
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- Publication number
- JP2016510326A5 JP2016510326A5 JP2015553856A JP2015553856A JP2016510326A5 JP 2016510326 A5 JP2016510326 A5 JP 2016510326A5 JP 2015553856 A JP2015553856 A JP 2015553856A JP 2015553856 A JP2015553856 A JP 2015553856A JP 2016510326 A5 JP2016510326 A5 JP 2016510326A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- treatment
- compound
- cardiovascular disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 19
- 150000001875 compounds Chemical class 0.000 claims 16
- 208000024172 Cardiovascular disease Diseases 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 206010007556 Cardiac failure acute Diseases 0.000 claims 2
- 206010019280 Heart failures Diseases 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 208000019553 vascular disease Diseases 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361754237P | 2013-01-18 | 2013-01-18 | |
| US61/754,237 | 2013-01-18 | ||
| US201361782781P | 2013-03-14 | 2013-03-14 | |
| US61/782,781 | 2013-03-14 | ||
| PCT/US2014/012085 WO2014113696A1 (en) | 2013-01-18 | 2014-01-17 | Nitroxyl donors with improved therapeutic index |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017005276A Division JP6311038B2 (ja) | 2013-01-18 | 2017-01-16 | 治療指数の改善されたニトロキシル供与体 |
| JP2018228317A Division JP6656345B2 (ja) | 2013-01-18 | 2018-12-05 | 治療指数の改善されたニトロキシル供与体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016510326A JP2016510326A (ja) | 2016-04-07 |
| JP2016510326A5 true JP2016510326A5 (enExample) | 2017-02-23 |
| JP6449171B2 JP6449171B2 (ja) | 2019-01-09 |
Family
ID=50064795
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015553858A Expired - Fee Related JP6533159B2 (ja) | 2013-01-18 | 2014-01-17 | ニトロキシル供与体を含む医薬組成物 |
| JP2015553856A Expired - Fee Related JP6449171B2 (ja) | 2013-01-18 | 2014-01-17 | 治療指数の改善されたニトロキシル供与体 |
| JP2017005276A Expired - Fee Related JP6311038B2 (ja) | 2013-01-18 | 2017-01-16 | 治療指数の改善されたニトロキシル供与体 |
| JP2018228317A Active JP6656345B2 (ja) | 2013-01-18 | 2018-12-05 | 治療指数の改善されたニトロキシル供与体 |
| JP2019096869A Expired - Fee Related JP6801045B2 (ja) | 2013-01-18 | 2019-05-23 | ニトロキシル供与体を含む医薬組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015553858A Expired - Fee Related JP6533159B2 (ja) | 2013-01-18 | 2014-01-17 | ニトロキシル供与体を含む医薬組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017005276A Expired - Fee Related JP6311038B2 (ja) | 2013-01-18 | 2017-01-16 | 治療指数の改善されたニトロキシル供与体 |
| JP2018228317A Active JP6656345B2 (ja) | 2013-01-18 | 2018-12-05 | 治療指数の改善されたニトロキシル供与体 |
| JP2019096869A Expired - Fee Related JP6801045B2 (ja) | 2013-01-18 | 2019-05-23 | ニトロキシル供与体を含む医薬組成物 |
Country Status (29)
| Country | Link |
|---|---|
| US (13) | US8987326B2 (enExample) |
| EP (5) | EP3284463B1 (enExample) |
| JP (5) | JP6533159B2 (enExample) |
| KR (2) | KR102177899B1 (enExample) |
| CN (4) | CN110179777B (enExample) |
| AU (5) | AU2014207404B2 (enExample) |
| BR (2) | BR112015017251B1 (enExample) |
| CA (2) | CA2898445C (enExample) |
| CY (3) | CY1120535T1 (enExample) |
| DK (3) | DK3284463T3 (enExample) |
| ES (4) | ES2659969T3 (enExample) |
| HK (1) | HK1251170B (enExample) |
| HR (3) | HRP20180121T1 (enExample) |
| HU (3) | HUE036589T2 (enExample) |
| IL (4) | IL239906B (enExample) |
| LT (3) | LT3284463T (enExample) |
| MX (2) | MX363843B (enExample) |
| NZ (4) | NZ709986A (enExample) |
| PL (3) | PL2945621T3 (enExample) |
| PT (3) | PT2945620T (enExample) |
| RS (3) | RS59434B1 (enExample) |
| RU (3) | RU2684916C2 (enExample) |
| SG (6) | SG11201505568PA (enExample) |
| SI (3) | SI2945620T1 (enExample) |
| SM (3) | SMT201900575T1 (enExample) |
| TR (1) | TR201802211T4 (enExample) |
| TW (3) | TWI712409B (enExample) |
| WO (2) | WO2014113696A1 (enExample) |
| ZA (2) | ZA201505090B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE029309T2 (en) | 2006-03-17 | 2017-02-28 | Univ Johns Hopkins | N-hydroxylsulfonamide derivatives as novel physiologically useful nitroxyl donors |
| CA2852914C (en) | 2011-10-17 | 2019-11-26 | The Johns Hopkins University | Meldrum's acid, barbituric acid and pyrazolone derivatives substituted with hydroxylamine as hno donors |
| BR112015017251B1 (pt) | 2013-01-18 | 2021-10-26 | Cardioxyl Pharmaceuticals, Inc. | Composições farmacêuticas compreendendo doadores de nitroxil, misturas e usos das referidas composições farmacêuticas |
| ES2734060T3 (es) | 2014-01-17 | 2019-12-04 | Cardioxyl Pharmaceuticals Inc | Donadores de nitroxilo de N-hidroximetanosulfonamida |
| ES2749682T3 (es) | 2014-05-27 | 2020-03-23 | Cardioxyl Pharmaceuticals Inc | Derivados de pirazolona como donadores de nitroxilo |
| US9464061B2 (en) | 2014-05-27 | 2016-10-11 | The Johns Hopkins University | N-hydroxylamino-barbituric acid derivatives |
| CN108349911B (zh) | 2015-09-07 | 2022-05-13 | 浙江华海药业股份有限公司 | 可释放一氧化氮的前药分子 |
| JP6889704B2 (ja) | 2015-10-19 | 2021-06-18 | カルディオキシル ファーマシューティカルズ，インク． | ニトロキシルドナーとしてのピラゾロン誘導体 |
| EP3365325A1 (en) | 2015-10-19 | 2018-08-29 | Cardioxyl Pharmaceuticals Inc. | N-hydroxylsulfonamide derivatives as nitroxyl donors |
| KR20190070912A (ko) | 2016-07-28 | 2019-06-21 | 더 존스 홉킨스 유니버시티 | O-치환된 히드록삼산 |
| AU2018205621B2 (en) * | 2017-01-03 | 2023-01-05 | Cardioxyl Pharmaceuticals, Inc. | Method of administering nitroxyl donating compounds |
| CN110536683A (zh) * | 2017-04-18 | 2019-12-03 | 基恩菲特公司 | 包含PPAR激动剂如伊拉非诺和乙酰CoA羧化酶ACC抑制剂的组合 |
| CN116283762B (zh) * | 2023-03-28 | 2025-08-12 | 昆山市第一人民医院 | 一种用于制备白鲜碱的中间体化合物及其制备方法、白鲜碱的制备方法 |
| WO2025043108A1 (en) | 2023-08-23 | 2025-02-27 | Bristol -Myers S Quibb Company | Co-crystals of nitroxyl donating compounds |
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| US1017976A (en) | 1911-08-25 | 1912-02-20 | Rudolph Koch | Automatic mail-bag catcher and deliverer. |
| US1021340A (en) | 1911-10-14 | 1912-03-26 | William A Scott | Means for attaching binding-posts to dry batteries. |
| US3751255A (en) | 1972-03-24 | 1973-08-07 | Eastman Kodak Co | Photosensitive and thermosensitive element, composition and process |
| JPS567710A (en) | 1979-06-28 | 1981-01-27 | Sansho Seiyaku Kk | Whitening cosmetic |
| US4539321A (en) | 1981-10-26 | 1985-09-03 | William H. Rorer, Inc. | 5-Diaza-aryl-3-substituted pyridone compounds |
| ATE66143T1 (de) | 1985-01-11 | 1991-08-15 | Abbott Lab | Feste zubereitung mit langsamer freisetzung. |
| US4663351A (en) | 1985-08-23 | 1987-05-05 | Berlex Laboratories, Inc. | Dobutamine tri-isobutyric acid ester and the use thereof as a cardiotonic agent |
| US4798824A (en) | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| JPH01221371A (ja) | 1988-02-29 | 1989-09-04 | Hokko Chem Ind Co Ltd | 環状オキシアミン誘導体の製造方法 |
| JPH01221372A (ja) | 1988-03-01 | 1989-09-04 | Hokko Chem Ind Co Ltd | 環状アシルヒドロキシルアミン誘導体 |
| JPH0221372A (ja) | 1988-07-08 | 1990-01-24 | Sharp Corp | はんだ付検査装置 |
| JPH0828240B2 (ja) | 1990-05-25 | 1996-03-21 | 矢崎総業株式会社 | 電線相互の圧着接続構造及び圧着接続方法 |
| JP2773959B2 (ja) | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
| JPH04321671A (ja) | 1991-04-17 | 1992-11-11 | Mitsubishi Petrochem Co Ltd | カルバモイルトリアゾール誘導体およびそれを有効成分とする除草剤 |
| CN1143950A (zh) * | 1994-01-19 | 1997-02-26 | 比克荷兰有限公司 | 含硝酰基的苄胺衍生物及其在治疗心血管疾病和治疗升高眼压中的应用 |
| US6156728A (en) * | 1996-11-01 | 2000-12-05 | Genentech, Inc. | Treatment of inner ear hair cells |
| JPH10142729A (ja) | 1996-11-05 | 1998-05-29 | Fuji Photo Film Co Ltd | 熱現像画像記録材料 |
| CA2306914A1 (en) | 1997-10-24 | 1999-05-06 | Shionogi & Co., Ltd. | Antirheumatic |
| ATE236136T1 (de) * | 1998-01-16 | 2003-04-15 | Hoffmann La Roche | Benzosulfonderivate |
| US6295153B1 (en) | 1998-06-04 | 2001-09-25 | Board Of Regents, The University Of Texas System | Digital optical chemistry micromirror imager |
| UA73092C2 (uk) | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| AU4800999A (en) | 1998-07-28 | 2000-02-21 | Tanabe Seiyaku Co., Ltd. | Preparation capable of releasing drug at target site in intestine |
| GB9918684D0 (en) | 1999-08-09 | 1999-10-13 | Novartis Ag | Organic compounds |
| JP2002072459A (ja) | 2000-08-28 | 2002-03-12 | Toyo Gosei Kogyo Kk | 光酸発生剤及びそれを含有する感光性樹脂組成物 |
| ES2267853T3 (es) | 2000-12-13 | 2007-03-16 | Wyeth | Inhibidroes de sulfonamida heteriociclicos de la produccion de beta amiloides. |
| EP1219306A1 (en) * | 2000-12-29 | 2002-07-03 | Nicox S.A. | Compositions comprising cyclodextrins and NO- releasing drugs |
| GB0114223D0 (en) | 2001-06-12 | 2001-08-01 | Ici Plc | Catalytic oxidation process |
| US20040038947A1 (en) | 2002-06-14 | 2004-02-26 | The Gov. Of The U.S. Of America As Represented By The Sec. Of The Dept. Of Health & Human Services | Method of treating ischemia/reperfusion injury with nitroxyl donors |
| US6936639B2 (en) | 2002-08-21 | 2005-08-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroxyl progenitors in the treatment of heart failure |
| US20050250737A1 (en) * | 2003-11-12 | 2005-11-10 | Allergan, Inc. | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods |
| WO2005061519A1 (en) | 2003-12-19 | 2005-07-07 | Takeda San Diego, Inc. | Kinase inhibitors |
| US20090281067A1 (en) | 2004-01-30 | 2009-11-12 | The John Hopkins University | Nitroxyl progenitor compounds and methods of use |
| US8168771B2 (en) | 2005-01-31 | 2012-05-01 | The Johns Hopkins University | Use of consensus sequence as vaccine antigen to enhance recognition of virulent viral variants |
| JP2008543947A (ja) | 2005-06-23 | 2008-12-04 | ジョンズ ホプキンス ユニバーシティ | チオール感受性の正の変力物質 |
| HUE029309T2 (en) | 2006-03-17 | 2017-02-28 | Univ Johns Hopkins | N-hydroxylsulfonamide derivatives as novel physiologically useful nitroxyl donors |
| EP2010476A4 (en) | 2006-04-13 | 2011-01-26 | Univ Wake Forest Health Sciences | NITROXYL DISPENSERS FROM C-NITROSO COMPOUNDS |
| MX2010003232A (es) | 2007-09-26 | 2010-08-23 | Univ Johns Hopkins | Derivados de n-hidroxisulfonamida como nuevos donadores de nitroxilo fisiologicamente utiles. |
| HUE030372T2 (en) * | 2008-05-07 | 2017-05-29 | Cardioxyl Pharmaceuticals Inc | New nitroso compounds as nitroxyl donors and methods for their use |
| WO2011063339A1 (en) | 2009-11-23 | 2011-05-26 | Cardioxyl Pharmaceuticals, Inc. | Nitroxyl donors for the treatment of pulmonary hypertension |
| WO2011071951A2 (en) | 2009-12-07 | 2011-06-16 | Johns Hopkins University | N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives |
| JP5832447B2 (ja) | 2009-12-07 | 2015-12-16 | ザ ジョンズ ホプキンス ユニバーシティ | ビスアシル化ヒドロキシルアミン誘導体 |
| CA2852914C (en) | 2011-10-17 | 2019-11-26 | The Johns Hopkins University | Meldrum's acid, barbituric acid and pyrazolone derivatives substituted with hydroxylamine as hno donors |
| EP2914579A1 (en) | 2012-11-01 | 2015-09-09 | The Johns Hopkins University | Controlled hno release through intramolecular cyclization-elimination |
| BR112015017251B1 (pt) | 2013-01-18 | 2021-10-26 | Cardioxyl Pharmaceuticals, Inc. | Composições farmacêuticas compreendendo doadores de nitroxil, misturas e usos das referidas composições farmacêuticas |
| ES2734060T3 (es) | 2014-01-17 | 2019-12-04 | Cardioxyl Pharmaceuticals Inc | Donadores de nitroxilo de N-hidroximetanosulfonamida |
| US9464061B2 (en) | 2014-05-27 | 2016-10-11 | The Johns Hopkins University | N-hydroxylamino-barbituric acid derivatives |
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2014
- 2014-01-17 BR BR112015017251-2A patent/BR112015017251B1/pt active IP Right Grant
- 2014-01-17 NZ NZ709986A patent/NZ709986A/en unknown
- 2014-01-17 EP EP17195759.0A patent/EP3284463B1/en active Active
- 2014-01-17 TW TW107143952A patent/TWI712409B/zh not_active IP Right Cessation
- 2014-01-17 PL PL14703010T patent/PL2945621T3/pl unknown
- 2014-01-17 CN CN201910446030.8A patent/CN110179777B/zh active Active
- 2014-01-17 PT PT147030092T patent/PT2945620T/pt unknown
- 2014-01-17 RS RSP20191352 patent/RS59434B1/sr unknown
- 2014-01-17 SI SI201430507T patent/SI2945620T1/en unknown
- 2014-01-17 EP EP14703010.0A patent/EP2945621B1/en active Active
- 2014-01-17 LT LT17195759T patent/LT3284463T/lt unknown
- 2014-01-17 HU HUE14703009A patent/HUE036589T2/hu unknown
- 2014-01-17 US US14/158,456 patent/US8987326B2/en active Active
- 2014-01-17 TW TW103101912A patent/TWI619491B/zh not_active IP Right Cessation
- 2014-01-17 CN CN201480013565.1A patent/CN105073105B/zh active Active
- 2014-01-17 EP EP18190818.7A patent/EP3427728B1/en active Active
- 2014-01-17 KR KR1020157022200A patent/KR102177899B1/ko not_active Expired - Fee Related
- 2014-01-17 SG SG11201505568PA patent/SG11201505568PA/en unknown
- 2014-01-17 RU RU2015134583A patent/RU2684916C2/ru active
- 2014-01-17 DK DK17195759T patent/DK3284463T3/da active
- 2014-01-17 TR TR2018/02211T patent/TR201802211T4/tr unknown
- 2014-01-17 HU HUE14703010A patent/HUE041861T2/hu unknown
- 2014-01-17 SM SM20190575T patent/SMT201900575T1/it unknown
- 2014-01-17 HR HRP20180121TT patent/HRP20180121T1/hr unknown
- 2014-01-17 CA CA2898445A patent/CA2898445C/en active Active
- 2014-01-17 KR KR1020157022192A patent/KR102277165B1/ko active Active
- 2014-01-17 TW TW103101913A patent/TWI686193B/zh active
- 2014-01-17 SI SI201431361T patent/SI3284463T1/sl unknown
- 2014-01-17 WO PCT/US2014/012085 patent/WO2014113696A1/en not_active Ceased
- 2014-01-17 CN CN201480013223.XA patent/CN105142627B/zh active Active
- 2014-01-17 PT PT171957590T patent/PT3284463T/pt unknown
- 2014-01-17 EP EP14703009.2A patent/EP2945620B1/en active Active
- 2014-01-17 NZ NZ748771A patent/NZ748771A/en unknown
- 2014-01-17 JP JP2015553858A patent/JP6533159B2/ja not_active Expired - Fee Related
- 2014-01-17 AU AU2014207404A patent/AU2014207404B2/en active Active
- 2014-01-17 LT LTEP14703010.0T patent/LT2945621T/lt unknown
- 2014-01-17 RU RU2018143994A patent/RU2018143994A/ru unknown
- 2014-01-17 RS RS20180099A patent/RS56968B1/sr unknown
- 2014-01-17 NZ NZ748769A patent/NZ748769A/en unknown
- 2014-01-17 EP EP19181338.5A patent/EP3567031A1/en not_active Withdrawn
- 2014-01-17 PL PL17195759T patent/PL3284463T3/pl unknown
- 2014-01-17 ES ES14703009.2T patent/ES2659969T3/es active Active
- 2014-01-17 DK DK14703010.0T patent/DK2945621T3/en active
- 2014-01-17 SM SM20180088T patent/SMT201800088T1/it unknown
- 2014-01-17 SM SM20190027T patent/SMT201900027T1/it unknown
- 2014-01-17 NZ NZ709985A patent/NZ709985A/en unknown
- 2014-01-17 SG SG10201913286PA patent/SG10201913286PA/en unknown
- 2014-01-17 ES ES18190818T patent/ES2882279T3/es active Active
- 2014-01-17 PL PL14703009T patent/PL2945620T3/pl unknown
- 2014-01-17 HU HUE17195759A patent/HUE046722T2/hu unknown
- 2014-01-17 LT LTEP14703009.2T patent/LT2945620T/lt unknown
- 2014-01-17 BR BR112015017241-5A patent/BR112015017241B1/pt active IP Right Grant
- 2014-01-17 SG SG11201505567RA patent/SG11201505567RA/en unknown
- 2014-01-17 SI SI201430983T patent/SI2945621T1/sl unknown
- 2014-01-17 RS RS20181599A patent/RS58174B1/sr unknown
- 2014-01-17 HR HRP20182144TT patent/HRP20182144T1/hr unknown
- 2014-01-17 CN CN201810074807.8A patent/CN108610312A/zh active Pending
- 2014-01-17 RU RU2015134581A patent/RU2676277C2/ru active
- 2014-01-17 SG SG10201802862WA patent/SG10201802862WA/en unknown
- 2014-01-17 SG SG10201802855TA patent/SG10201802855TA/en unknown
- 2014-01-17 PT PT14703010T patent/PT2945621T/pt unknown
- 2014-01-17 CA CA2898443A patent/CA2898443C/en active Active
- 2014-01-17 DK DK14703009.2T patent/DK2945620T3/en active
- 2014-01-17 WO PCT/US2014/012089 patent/WO2014113700A1/en not_active Ceased
- 2014-01-17 ES ES14703010T patent/ES2705240T3/es active Active
- 2014-01-17 MX MX2015009269A patent/MX363843B/es active IP Right Grant
- 2014-01-17 MX MX2015009276A patent/MX373176B/es active IP Right Grant
- 2014-01-17 AU AU2014207408A patent/AU2014207408C1/en active Active
- 2014-01-17 ES ES17195759T patent/ES2751922T3/es active Active
- 2014-01-17 SG SG10201913441RA patent/SG10201913441RA/en unknown
- 2014-01-17 US US14/761,934 patent/US10245249B2/en active Active
- 2014-01-17 JP JP2015553856A patent/JP6449171B2/ja not_active Expired - Fee Related
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2015
- 2015-03-07 US US14/641,377 patent/US9156804B2/en active Active
- 2015-07-13 IL IL239906A patent/IL239906B/en active IP Right Grant
- 2015-07-15 IL IL239952A patent/IL239952B/en active IP Right Grant
- 2015-07-15 ZA ZA2015/05090A patent/ZA201505090B/en unknown
- 2015-10-09 US US14/880,173 patent/US9586896B2/en active Active
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2016
- 2016-07-07 ZA ZA2016/04798A patent/ZA201604798B/en unknown
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2017
- 2017-01-10 AU AU2017200147A patent/AU2017200147B2/en active Active
- 2017-01-16 JP JP2017005276A patent/JP6311038B2/ja not_active Expired - Fee Related
- 2017-02-13 US US15/430,946 patent/US9968584B2/en active Active
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2018
- 2018-01-12 CY CY20181100038T patent/CY1120535T1/el unknown
- 2018-04-23 IL IL258882A patent/IL258882A/en active IP Right Grant
- 2018-04-24 US US15/960,993 patent/US10213408B2/en active Active
- 2018-05-09 AU AU2018203240A patent/AU2018203240B2/en active Active
- 2018-05-09 IL IL25923318A patent/IL259233B/en active IP Right Grant
- 2018-08-20 HK HK18110676.0A patent/HK1251170B/en unknown
- 2018-10-05 AU AU2018241168A patent/AU2018241168B2/en active Active
- 2018-12-05 JP JP2018228317A patent/JP6656345B2/ja active Active
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2019
- 2019-01-08 US US16/242,139 patent/US10517847B2/en active Active
- 2019-01-15 CY CY20191100046T patent/CY1121480T1/el unknown
- 2019-03-29 US US16/370,443 patent/US10548872B2/en active Active
- 2019-05-23 JP JP2019096869A patent/JP6801045B2/ja not_active Expired - Fee Related
- 2019-10-16 CY CY20191101084T patent/CY1122177T1/el unknown
- 2019-10-23 HR HRP20191919TT patent/HRP20191919T8/hr unknown
- 2019-12-23 US US16/724,657 patent/US10792273B2/en active Active
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2020
- 2020-01-31 US US16/779,015 patent/US11304924B2/en active Active
- 2020-10-05 US US17/063,372 patent/US11273143B2/en active Active
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2022
- 2022-03-14 US US17/694,500 patent/US11786501B2/en active Active
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2023
- 2023-09-22 US US18/371,722 patent/US12186301B2/en active Active
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