JP2014077003A5 - - Google Patents
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- Publication number
- JP2014077003A5 JP2014077003A5 JP2013257143A JP2013257143A JP2014077003A5 JP 2014077003 A5 JP2014077003 A5 JP 2014077003A5 JP 2013257143 A JP2013257143 A JP 2013257143A JP 2013257143 A JP2013257143 A JP 2013257143A JP 2014077003 A5 JP2014077003 A5 JP 2014077003A5
- Authority
- JP
- Japan
- Prior art keywords
- ischemia
- pharmaceutical composition
- final dose
- reperfusion injury
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/466,170 | 2009-05-14 | ||
| US12/466,170 US7928067B2 (en) | 2009-05-14 | 2009-05-14 | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012511009A Division JP5570590B2 (ja) | 2009-05-14 | 2010-05-13 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014077003A JP2014077003A (ja) | 2014-05-01 |
| JP2014077003A5 true JP2014077003A5 (enExample) | 2014-07-10 |
| JP5767307B2 JP5767307B2 (ja) | 2015-08-19 |
Family
ID=42244916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012511009A Expired - Fee Related JP5570590B2 (ja) | 2009-05-14 | 2010-05-13 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
| JP2013257143A Expired - Fee Related JP5767307B2 (ja) | 2009-05-14 | 2013-12-12 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012511009A Expired - Fee Related JP5570590B2 (ja) | 2009-05-14 | 2010-05-13 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US7928067B2 (enExample) |
| EP (1) | EP2429519B1 (enExample) |
| JP (2) | JP5570590B2 (enExample) |
| KR (1) | KR101636395B1 (enExample) |
| CN (1) | CN102802622B (enExample) |
| AU (1) | AU2010249001B2 (enExample) |
| BR (1) | BRPI1012182A2 (enExample) |
| CA (1) | CA2761798C (enExample) |
| DK (1) | DK2429519T3 (enExample) |
| ES (1) | ES2470673T3 (enExample) |
| IL (2) | IL216349A (enExample) |
| MX (2) | MX347460B (enExample) |
| NZ (1) | NZ596364A (enExample) |
| PL (1) | PL2429519T3 (enExample) |
| SG (1) | SG176062A1 (enExample) |
| WO (1) | WO2010132657A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8541396B2 (en) | 2009-04-24 | 2013-09-24 | National University Of Singapore | Morpholin-4-ium 4 methoxyphenyl (morpholino) phosphinodithioate (GYY4137) as a novel vasodilator agent |
| US7928067B2 (en) * | 2009-05-14 | 2011-04-19 | Ischemix Llc | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
| ES2640474T3 (es) * | 2010-11-18 | 2017-11-03 | Ischemix Llc | Compuestos lipoílicos y su uso para el tratamiento de la lesión isquémica |
| EP2540292A1 (en) * | 2011-06-28 | 2013-01-02 | Nestec S.A. | DHA and EPA in the reduction of oxidative stress |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| EP2875826B1 (en) | 2012-05-11 | 2017-08-23 | KAEL-GemVax Co.,Ltd | Composition for preventing or treating sepsis |
| CN104507961B (zh) | 2012-05-11 | 2018-08-14 | 珍白斯凯尔有限公司 | 抗炎性肽及包含其的组合物 |
| WO2014010971A1 (ko) | 2012-07-11 | 2014-01-16 | 주식회사 카엘젬백스 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
| KR102258864B1 (ko) * | 2013-04-19 | 2021-06-01 | 주식회사 젬백스앤카엘 | 허혈성 손상 치료 및 예방용 조성물 |
| AU2014275610B2 (en) | 2013-06-07 | 2018-06-14 | Gemvax & Kael Co., Ltd. | Biological markers useful in cancer immunotherapy |
| ES2808076T3 (es) | 2013-06-21 | 2021-02-25 | Gemvax & Kael Co Ltd | Regulador de la secreción hormonal, composición que lo contiene y procedimiento para controlar la secreción hormonal mediante su uso |
| ES2773296T3 (es) | 2013-10-23 | 2020-07-10 | Gemvax & Kael Co Ltd | Composición para tratar y prevenir la hiperplasia prostática benigna |
| KR102359396B1 (ko) | 2013-11-22 | 2022-02-08 | 주식회사 젬백스앤카엘 | 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
| JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー，リミティド | 前立腺癌治療用組成物 |
| ES2908096T3 (es) | 2014-04-11 | 2022-04-27 | Gemvax & Kael Co Ltd | Péptido con actividad inhibidora de la fibrosis y composición que lo contiene |
| WO2015167067A1 (ko) | 2014-04-30 | 2015-11-05 | 주식회사 카엘젬백스 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
| WO2015174948A1 (en) | 2014-05-14 | 2015-11-19 | Ischemix, LLC | Formulations comprising lipoyl compounds |
| CN104095835A (zh) * | 2014-06-20 | 2014-10-15 | 广州军区广州总医院 | 对羟基苄叉丙酮在制备预防和/或治疗肝缺血/再灌注损伤药物中的应用 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| US10835582B2 (en) | 2015-02-27 | 2020-11-17 | Gemvax & Kael Co. Ltd. | Peptide for preventing hearing loss, and composition comprising same |
| JP6923453B2 (ja) | 2015-07-02 | 2021-08-18 | ジェムバックス アンド カエル カンパニー，リミティド | 抗ウイルス活性効能を有するペプチド及びこれを含む組成物 |
| ES2949697T3 (es) | 2016-04-07 | 2023-10-02 | Gemvax & Kael Co Ltd | Péptido que tiene efectos de aumento de la actividad telomerasa y de extensión de los telómeros, y composición que contienen el mismo |
| CN106083800A (zh) * | 2016-06-13 | 2016-11-09 | 崔坤峰 | 氯普噻吨的药物组合物及对脑缺血再灌注损伤的保护作用 |
| UA124019C2 (uk) * | 2016-10-05 | 2021-07-07 | Мітобрідж, Інк. | Спосіб лікування гострого пошкодження нирок |
| EP3615023B1 (en) * | 2017-04-25 | 2023-06-21 | Ischemix LLC | Lipoyl-glu-ala for the treatment of neurodegenerative damage caused by traumatic brain injury |
| KR102139678B1 (ko) | 2017-11-24 | 2020-07-31 | 전북대학교 산학협력단 | N-아세틸 또는 n-아실 아미노산을 포함하는 아토피 또는 가려움증 치료용 조성물 |
| KR102112949B1 (ko) | 2019-02-12 | 2020-05-19 | 남현규 | 복합 효모 발효로 불용 단백질을 가용화하여 화장품원료를 추출하는 화장품원료 제조방법 |
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| CA1219824A (en) | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
| US5288706A (en) * | 1987-12-25 | 1994-02-22 | Mitsui Toatsu Chemicals, Incorporated | Medicament for prevention and remedy of diseases of the pancreas and others |
| FR2653334B1 (fr) | 1989-10-19 | 1991-12-20 | Erphar Ste Civile | Preparation cosmetique de bronzage. |
| PT95826B (pt) | 1989-11-09 | 1997-11-28 | Asta Medica Ag | Processo para a preparacao de composicoes farmaceuticas contendo como ingrediente activo acido r-alfa-liponico ou acido s-alfa-liponico |
| DE4000397A1 (de) | 1990-01-09 | 1991-07-11 | Hoechst Ag | Lipidselektive antioxidantien sowie deren herstellung und verwendung |
| JPH07505900A (ja) | 1992-04-24 | 1995-06-29 | バイオコンパテイブルズ・リミテツド | 金属皮膜 |
| DE4235912C2 (de) | 1992-10-23 | 2002-12-05 | Viatris Gmbh | Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung |
| DE4433764A1 (de) | 1994-09-22 | 1996-03-28 | Asta Medica Ag | Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit |
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| JPH0990542A (ja) | 1995-09-28 | 1997-04-04 | Konica Corp | ハロゲン化銀写真感光材料 |
| FR2741075B1 (fr) | 1995-11-15 | 1998-01-30 | Rech De Pathologie Appliquee S | Conjugues peptidiques, leur utilisation a titre de medicament et compositions les contenant |
| IL123887A0 (en) | 1997-04-02 | 1998-10-30 | Sankyo Co | Dithiolan derivatives their use and pharmaceutical compositions containing the same |
| JPH117099A (ja) | 1997-06-13 | 1999-01-12 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
| US6090842A (en) | 1998-03-10 | 2000-07-18 | The Regents Of The University Of California | Lipoic acid analogs |
| DE19834608A1 (de) | 1998-07-31 | 2000-02-03 | Basf Ag | Kristallmodifikation der Liponsäure |
| JP2000169371A (ja) | 1998-10-02 | 2000-06-20 | Sankyo Co Ltd | ジチオラン誘導体を含有する医薬 |
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| US20110212954A1 (en) | 2008-11-07 | 2011-09-01 | Mario Brufani | Alpha-lipoic acid derivatives and their use in drug preparation |
| US7928067B2 (en) | 2009-05-14 | 2011-04-19 | Ischemix Llc | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
| US8080674B2 (en) | 2009-06-12 | 2011-12-20 | Ampac Fine Chemicals Llc. | Preparation of polymer-free R-(+)-α-lipoic acid magnesium salt |
| EP3069612A3 (en) | 2009-06-15 | 2016-10-19 | Encore Health, LLC | Dithiol compounds, derivatives, and uses therefor |
| ES2579173T3 (es) | 2009-06-15 | 2016-08-05 | Encore Health, Llc | Ésteres de colina para tratar presbicia y cataratas |
| IT1397154B1 (it) | 2010-01-04 | 2013-01-04 | Ghelardini | Composti ad efficacia sia analgesica che antiperalgesica. |
| ES2640474T3 (es) | 2010-11-18 | 2017-11-03 | Ischemix Llc | Compuestos lipoílicos y su uso para el tratamiento de la lesión isquémica |
| WO2015174948A1 (en) | 2014-05-14 | 2015-11-19 | Ischemix, LLC | Formulations comprising lipoyl compounds |
| US20150329519A1 (en) | 2014-05-14 | 2015-11-19 | Ischemix, LLC | Formulations Comprising Lipoyl Compounds |
-
2009
- 2009-05-14 US US12/466,170 patent/US7928067B2/en active Active
-
2010
- 2010-05-13 BR BRPI1012182A patent/BRPI1012182A2/pt not_active IP Right Cessation
- 2010-05-13 SG SG2011083862A patent/SG176062A1/en unknown
- 2010-05-13 WO PCT/US2010/034701 patent/WO2010132657A1/en not_active Ceased
- 2010-05-13 EP EP10720092.5A patent/EP2429519B1/en active Active
- 2010-05-13 MX MX2013004034A patent/MX347460B/es unknown
- 2010-05-13 US US13/319,839 patent/US8772250B2/en not_active Expired - Fee Related
- 2010-05-13 NZ NZ596364A patent/NZ596364A/xx not_active IP Right Cessation
- 2010-05-13 DK DK10720092.5T patent/DK2429519T3/da active
- 2010-05-13 AU AU2010249001A patent/AU2010249001B2/en not_active Ceased
- 2010-05-13 CN CN201080031479.5A patent/CN102802622B/zh not_active Expired - Fee Related
- 2010-05-13 MX MX2011012095A patent/MX2011012095A/es active IP Right Grant
- 2010-05-13 ES ES10720092.5T patent/ES2470673T3/es active Active
- 2010-05-13 CA CA2761798A patent/CA2761798C/en active Active
- 2010-05-13 JP JP2012511009A patent/JP5570590B2/ja not_active Expired - Fee Related
- 2010-05-13 PL PL10720092T patent/PL2429519T3/pl unknown
- 2010-05-13 KR KR1020117029417A patent/KR101636395B1/ko not_active Expired - Fee Related
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2011
- 2011-03-04 US US13/041,001 patent/US8772249B2/en not_active Expired - Fee Related
- 2011-11-14 IL IL216349A patent/IL216349A/en active IP Right Grant
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2013
- 2013-12-12 JP JP2013257143A patent/JP5767307B2/ja not_active Expired - Fee Related
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2014
- 2014-05-21 US US14/283,844 patent/US20140274917A1/en not_active Abandoned
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2015
- 2015-03-19 IL IL237820A patent/IL237820A/en active IP Right Grant
- 2015-10-20 US US14/918,175 patent/US9540417B2/en active Active