JP2014077003A5 - - Google Patents
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- Publication number
- JP2014077003A5 JP2014077003A5 JP2013257143A JP2013257143A JP2014077003A5 JP 2014077003 A5 JP2014077003 A5 JP 2014077003A5 JP 2013257143 A JP2013257143 A JP 2013257143A JP 2013257143 A JP2013257143 A JP 2013257143A JP 2014077003 A5 JP2014077003 A5 JP 2014077003A5
- Authority
- JP
- Japan
- Prior art keywords
- ischemia
- pharmaceutical composition
- final dose
- reperfusion injury
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/466,170 US7928067B2 (en) | 2009-05-14 | 2009-05-14 | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
| US12/466,170 | 2009-05-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012511009A Division JP5570590B2 (ja) | 2009-05-14 | 2010-05-13 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014077003A JP2014077003A (ja) | 2014-05-01 |
| JP2014077003A5 true JP2014077003A5 (enExample) | 2014-07-10 |
| JP5767307B2 JP5767307B2 (ja) | 2015-08-19 |
Family
ID=42244916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012511009A Expired - Fee Related JP5570590B2 (ja) | 2009-05-14 | 2010-05-13 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
| JP2013257143A Expired - Fee Related JP5767307B2 (ja) | 2009-05-14 | 2013-12-12 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012511009A Expired - Fee Related JP5570590B2 (ja) | 2009-05-14 | 2010-05-13 | 虚血および虚血・再灌流障害を治療するための組成物および方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US7928067B2 (enExample) |
| EP (1) | EP2429519B1 (enExample) |
| JP (2) | JP5570590B2 (enExample) |
| KR (1) | KR101636395B1 (enExample) |
| CN (1) | CN102802622B (enExample) |
| AU (1) | AU2010249001B2 (enExample) |
| BR (1) | BRPI1012182A2 (enExample) |
| CA (1) | CA2761798C (enExample) |
| DK (1) | DK2429519T3 (enExample) |
| ES (1) | ES2470673T3 (enExample) |
| IL (2) | IL216349A (enExample) |
| MX (2) | MX347460B (enExample) |
| NZ (1) | NZ596364A (enExample) |
| PL (1) | PL2429519T3 (enExample) |
| SG (1) | SG176062A1 (enExample) |
| WO (1) | WO2010132657A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8541396B2 (en) | 2009-04-24 | 2013-09-24 | National University Of Singapore | Morpholin-4-ium 4 methoxyphenyl (morpholino) phosphinodithioate (GYY4137) as a novel vasodilator agent |
| US7928067B2 (en) * | 2009-05-14 | 2011-04-19 | Ischemix Llc | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
| ES2640474T3 (es) * | 2010-11-18 | 2017-11-03 | Ischemix Llc | Compuestos lipoílicos y su uso para el tratamiento de la lesión isquémica |
| EP2540292A1 (en) * | 2011-06-28 | 2013-01-02 | Nestec S.A. | DHA and EPA in the reduction of oxidative stress |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| CN104507961B (zh) | 2012-05-11 | 2018-08-14 | 珍白斯凯尔有限公司 | 抗炎性肽及包含其的组合物 |
| WO2013169077A1 (ko) | 2012-05-11 | 2013-11-14 | 주식회사 카엘젬백스 | 악액질 예방 또는 치료용 조성물 |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| US9907838B2 (en) | 2013-04-19 | 2018-03-06 | Gemvax & Kael Co., Ltd. | Composition and methods for treating ischemic damage |
| JP6059405B2 (ja) | 2013-06-07 | 2017-01-11 | ジェムバックス アンド カエル カンパニー，リミティド | 癌の免疫学的治療に有用な生物学的マーカー |
| WO2014204281A1 (ko) | 2013-06-21 | 2014-12-24 | 주식회사 카엘젬백스 | 호르몬 분비 조절제, 이를 포함하는 조성물, 및 이를 사용한 호르몬 분비 조절 방법 |
| ES2773296T3 (es) | 2013-10-23 | 2020-07-10 | Gemvax & Kael Co Ltd | Composición para tratar y prevenir la hiperplasia prostática benigna |
| KR102359396B1 (ko) | 2013-11-22 | 2022-02-08 | 주식회사 젬백스앤카엘 | 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
| US11058744B2 (en) | 2013-12-17 | 2021-07-13 | Gemvax & Kael Co., Ltd. | Composition for treating prostate cancer |
| JP6420459B2 (ja) | 2014-04-11 | 2018-11-07 | ジェムバックス アンド カエル カンパニー，リミティド | 線維症抑制活性を有するペプチド及びこれを含む組成物 |
| CN106659149B (zh) | 2014-04-30 | 2020-05-19 | 珍白斯凯尔有限公司 | 用于器官、组织或细胞移植的组合物、试剂盒和移植方法 |
| WO2015174948A1 (en) | 2014-05-14 | 2015-11-19 | Ischemix, LLC | Formulations comprising lipoyl compounds |
| CN104095835A (zh) * | 2014-06-20 | 2014-10-15 | 广州军区广州总医院 | 对羟基苄叉丙酮在制备预防和/或治疗肝缺血/再灌注损伤药物中的应用 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| JP6751097B2 (ja) | 2015-02-27 | 2020-09-02 | ジェムバックス アンド カエル カンパニー，リミティド | 聴力損傷予防用ペプチド及びそれを含む組成物 |
| EP3318265B1 (en) | 2015-07-02 | 2021-08-18 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
| EP4272829A3 (en) | 2016-04-07 | 2024-01-17 | Gemvax & Kael Co., Ltd. | Peptide having effects of increasing telomerase activity and extending telomere, and composition containing same |
| CN106083800A (zh) * | 2016-06-13 | 2016-11-09 | 崔坤峰 | 氯普噻吨的药物组合物及对脑缺血再灌注损伤的保护作用 |
| WO2018067857A1 (en) * | 2016-10-05 | 2018-04-12 | Mitobridge, Inc. | Methods of treating acute kidney injury |
| CN110913851B (zh) | 2017-04-25 | 2023-08-25 | 伊斯切米克斯公司 | 治疗外伤性脑损伤的组合物和方法 |
| KR102139678B1 (ko) | 2017-11-24 | 2020-07-31 | 전북대학교 산학협력단 | N-아세틸 또는 n-아실 아미노산을 포함하는 아토피 또는 가려움증 치료용 조성물 |
| KR102112949B1 (ko) | 2019-02-12 | 2020-05-19 | 남현규 | 복합 효모 발효로 불용 단백질을 가용화하여 화장품원료를 추출하는 화장품원료 제조방법 |
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| US5288706A (en) * | 1987-12-25 | 1994-02-22 | Mitsui Toatsu Chemicals, Incorporated | Medicament for prevention and remedy of diseases of the pancreas and others |
| FR2653334B1 (fr) | 1989-10-19 | 1991-12-20 | Erphar Ste Civile | Preparation cosmetique de bronzage. |
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| DE4000397A1 (de) | 1990-01-09 | 1991-07-11 | Hoechst Ag | Lipidselektive antioxidantien sowie deren herstellung und verwendung |
| DE69324249D1 (de) | 1992-04-24 | 1999-05-06 | Biocompatibles Ltd | Metall beschichtungen |
| DE4235912C2 (de) | 1992-10-23 | 2002-12-05 | Viatris Gmbh | Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung |
| DE4433764A1 (de) | 1994-09-22 | 1996-03-28 | Asta Medica Ag | Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit |
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| AU728488B2 (en) | 1997-04-02 | 2001-01-11 | Sankyo Company Limited | Dithiolan derivatives, their preparation and their therapeutic effect |
| JPH117099A (ja) | 1997-06-13 | 1999-01-12 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
| US6090842A (en) | 1998-03-10 | 2000-07-18 | The Regents Of The University Of California | Lipoic acid analogs |
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| US7928067B2 (en) | 2009-05-14 | 2011-04-19 | Ischemix Llc | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
| US8080674B2 (en) | 2009-06-12 | 2011-12-20 | Ampac Fine Chemicals Llc. | Preparation of polymer-free R-(+)-α-lipoic acid magnesium salt |
| EP2442647B1 (en) | 2009-06-15 | 2016-03-16 | Encore Health LLC | Dithiol compounds, derivatives, and uses therefor |
| WO2010147962A1 (en) | 2009-06-15 | 2010-12-23 | Encore Health, Llc | Choline esters |
| IT1397154B1 (it) | 2010-01-04 | 2013-01-04 | Ghelardini | Composti ad efficacia sia analgesica che antiperalgesica. |
| ES2640474T3 (es) | 2010-11-18 | 2017-11-03 | Ischemix Llc | Compuestos lipoílicos y su uso para el tratamiento de la lesión isquémica |
| WO2015174948A1 (en) | 2014-05-14 | 2015-11-19 | Ischemix, LLC | Formulations comprising lipoyl compounds |
| US20150329519A1 (en) | 2014-05-14 | 2015-11-19 | Ischemix, LLC | Formulations Comprising Lipoyl Compounds |
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2009
- 2009-05-14 US US12/466,170 patent/US7928067B2/en active Active
-
2010
- 2010-05-13 SG SG2011083862A patent/SG176062A1/en unknown
- 2010-05-13 NZ NZ596364A patent/NZ596364A/xx not_active IP Right Cessation
- 2010-05-13 WO PCT/US2010/034701 patent/WO2010132657A1/en not_active Ceased
- 2010-05-13 DK DK10720092.5T patent/DK2429519T3/da active
- 2010-05-13 CN CN201080031479.5A patent/CN102802622B/zh active Active
- 2010-05-13 ES ES10720092.5T patent/ES2470673T3/es active Active
- 2010-05-13 BR BRPI1012182A patent/BRPI1012182A2/pt not_active Application Discontinuation
- 2010-05-13 MX MX2013004034A patent/MX347460B/es unknown
- 2010-05-13 PL PL10720092T patent/PL2429519T3/pl unknown
- 2010-05-13 JP JP2012511009A patent/JP5570590B2/ja not_active Expired - Fee Related
- 2010-05-13 CA CA2761798A patent/CA2761798C/en active Active
- 2010-05-13 KR KR1020117029417A patent/KR101636395B1/ko active Active
- 2010-05-13 EP EP10720092.5A patent/EP2429519B1/en active Active
- 2010-05-13 AU AU2010249001A patent/AU2010249001B2/en not_active Ceased
- 2010-05-13 US US13/319,839 patent/US8772250B2/en active Active
- 2010-05-13 MX MX2011012095A patent/MX2011012095A/es active IP Right Grant
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2011
- 2011-03-04 US US13/041,001 patent/US8772249B2/en active Active
- 2011-11-14 IL IL216349A patent/IL216349A/en active IP Right Grant
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2013
- 2013-12-12 JP JP2013257143A patent/JP5767307B2/ja not_active Expired - Fee Related
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2014
- 2014-05-21 US US14/283,844 patent/US20140274917A1/en not_active Abandoned
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2015
- 2015-03-19 IL IL237820A patent/IL237820A/en active IP Right Grant
- 2015-10-20 US US14/918,175 patent/US9540417B2/en active Active