|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
PT1523496E
(pt)
|
2002-07-18 |
2011-09-29 |
Merus B V |
Produção de misturas de anticorpos de forma recombinante
|
|
JP5620626B2
(ja)
|
2005-03-31 |
2014-11-05 |
中外製薬株式会社 |
会合制御によるポリペプチド製造方法
|
|
JP2009531324A
(ja)
|
2006-03-20 |
2009-09-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
癌標的化のための操作された抗前立腺幹細胞抗原（ｐｓｃａ）抗体
|
|
EP4218801A3
(en)
|
2006-03-31 |
2023-08-23 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
|
CA2647846C
(en)
|
2006-03-31 |
2016-06-21 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for controlling blood pharmacokinetics of antibodies
|
|
ME02371B
(me)
|
2006-09-29 |
2016-06-20 |
Oncomed Pharm Inc |
Sastojci i postupci za dijagnstikovanje i tretman raka
|
|
EP2139924B1
(en)
|
2007-03-29 |
2016-07-06 |
Genmab A/S |
Bispecific antibodies and methods for production thereof
|
|
SI2173379T1
(sl)
|
2007-07-02 |
2015-12-31 |
Oncomed Pharmaceuticals, Inc. |
Sestavki in postopki za zdravljenje in diagnosticiranje raka
|
|
US8940298B2
(en)
|
2007-09-04 |
2015-01-27 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting and detection
|
|
PL2202245T3
(pl)
|
2007-09-26 |
2017-02-28 |
Chugai Seiyaku Kabushiki Kaisha |
Sposób modyfikowania punktu izoelektrycznego przeciwciała poprzez podstawienie aminokwasu w cdr
|
|
EP2209498A2
(en)
*
|
2007-10-03 |
2010-07-28 |
Cornell University |
Treatment of proliferative disorders using antibodies to psma
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
EP2398504B1
(en)
|
2009-02-17 |
2018-11-28 |
Cornell Research Foundation, Inc. |
Methods and kits for diagnosis of cancer and prediction of therapeutic value
|
|
ES2537100T3
(es)
|
2009-04-07 |
2015-06-02 |
Roche Glycart Ag |
Anticuerpos biespecíficos trivalentes
|
|
CA2759233C
(en)
|
2009-04-27 |
2019-07-16 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
JP6091894B2
(ja)
|
2009-09-16 |
2017-03-15 |
ジェネンテック， インコーポレイテッド |
コイルドコイルおよび／またはテザー含有タンパク質複合体およびその使用
|
|
US20110172398A1
(en)
*
|
2009-10-02 |
2011-07-14 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules for anti-angiogenesis therapy
|
|
US8883145B2
(en)
|
2009-10-16 |
2014-11-11 |
Oncomed Pharmaceuticals, Inc. |
Methods of treatment with DLL4 antagonists and an anti-hypertensive agent
|
|
BR112012012887A2
(pt)
|
2009-12-02 |
2017-05-02 |
Imaginab Inc |
minicorpo e cys-diabody (cysdb) codificados por sequência de nucleótidos, respectivo uso e métodos de diagnósticos e de tratamento de câncer associado com a expressão de psma num sujeito.
|
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
|
CA2796181C
(en)
|
2010-04-20 |
2023-01-03 |
Genmab A/S |
Heterodimeric antibody fc-containing proteins and methods for production thereof
|
|
RU2624027C2
(ru)
|
2010-04-23 |
2017-06-30 |
Дженентек, Инк. |
Получение гетеромультимерных белков
|
|
CN103237811A
(zh)
|
2010-05-06 |
2013-08-07 |
诺瓦提斯公司 |
用于治疗性低密度脂蛋白相关蛋白质6(lrp6)多价抗体的组合物及使用方法
|
|
ES2659406T3
(es)
|
2010-05-06 |
2018-03-15 |
Novartis Ag |
Composiciones y procedimientos de uso para anticuerpos terapéuticos contra la proteína 6 relacionada con las lipoproteínas de baja densidad (LRP6)
|
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
|
CN103298937B
(zh)
|
2010-11-17 |
2016-05-25 |
中外制药株式会社 |
具有代替凝血因子viii的功能的功能的多特异性抗原结合分子
|
|
TR201815863T4
(tr)
|
2010-11-30 |
2018-11-21 |
Chugai Pharmaceutical Co Ltd |
Sitotoksisiteyi indükleyen terapötik madde.
|
|
US20120189633A1
(en)
|
2011-01-26 |
2012-07-26 |
Kolltan Pharmaceuticals, Inc. |
Anti-kit antibodies and uses thereof
|
|
US10689447B2
(en)
*
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
|
MX341921B
(es)
|
2011-02-28 |
2016-09-07 |
Hoffmann La Roche |
Proteinas de union a antigeno.
|
|
WO2012116927A1
(en)
|
2011-02-28 |
2012-09-07 |
F. Hoffmann-La Roche Ag |
Monovalent antigen binding proteins
|
|
US9527925B2
(en)
|
2011-04-01 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to VEGF and ANG2
|
|
SI2697257T1
(sl)
|
2011-04-13 |
2017-02-28 |
Bristol-Myers Squibb Company |
FC fuzijski proteini, ki vsebujejo nove linkerje ali razmestitve
|
|
RU2632647C2
(ru)
|
2011-04-22 |
2017-10-06 |
Аптево Рисерч Энд Девелопмент Ллс |
Белки, связывающие специфический мембранный антиген простаты, и соответствующие композиции и способы
|
|
WO2012163521A1
(en)
*
|
2011-05-27 |
2012-12-06 |
Dutalys |
Removal of monomeric targets
|
|
JP6081995B2
(ja)
|
2011-06-17 |
2017-02-15 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
癌の処置における治療抗体の標的としてのＦｒｉｚｚｌｅｄ２
|
|
UA117901C2
(uk)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
|
EP2543680A1
(en)
*
|
2011-07-07 |
2013-01-09 |
Centre National de la Recherche Scientifique |
Multispecific mutated antibody Fab fragments
|
|
AU2012284254B2
(en)
|
2011-07-15 |
2015-07-09 |
Oncomed Pharmaceuticals, Inc. |
RSPO binding agents and uses thereof
|
|
MX356947B
(es)
|
2011-08-23 |
2018-06-20 |
Roche Glycart Ag |
Anticuerpos bioespecíficos específicos para antígenos que activan células t y un antígeno tumoral y métodos de uso.
|
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
|
CN107722122B
(zh)
*
|
2011-09-23 |
2022-05-27 |
昂考梅德药品有限公司 |
Vegf/dll4结合剂及其应用
|
|
AU2015268749B2
(en)
*
|
2011-09-23 |
2017-05-25 |
Oncomed Pharmaceuticals, Inc. |
VEGF/DLL4 binding agents and uses thereof
|
|
WO2013060867A2
(en)
|
2011-10-27 |
2013-05-02 |
Genmab A/S |
Production of heterodimeric proteins
|
|
CN109111524B
(zh)
|
2011-10-31 |
2022-10-28 |
中外制药株式会社 |
控制了重链与轻链的缔合的抗原结合分子
|
|
ES2666856T3
(es)
|
2011-11-04 |
2018-05-08 |
Novartis Ag |
Proteína 6 relacionada con lipoproteínas de baja densidad (LRP6) - constructos extensores de la vida media
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對ｂｃｍａ之e3以及ｃｄ３的結合分子
|
|
WO2013078170A1
(en)
|
2011-11-21 |
2013-05-30 |
Genentech, Inc. |
Purification of anti-c-met antibodies
|
|
WO2013078191A1
(en)
|
2011-11-23 |
2013-05-30 |
Medimmune, Llc |
Binding molecules specific for her3 and uses thereof
|
|
EP2809682B1
(en)
|
2012-02-03 |
2020-04-08 |
F.Hoffmann-La Roche Ag |
Bispecific antibody molecules with antigen-transfected t-cells and their use in medicine
|
|
MX2014011818A
(es)
|
2012-04-05 |
2014-12-10 |
Hoffmann La Roche |
Anticuerpos biespecificos contra inductor debil de la apoptosis relacionado con el tnf (tweak) humana e il17 humana y usos de los mismos.
|
|
ES2740749T3
(es)
|
2012-04-20 |
2020-02-06 |
Merus Nv |
Métodos y medios para la producción de moléculas heterodiméricas similares a Ig
|
|
US9212227B2
(en)
|
2012-04-30 |
2015-12-15 |
Janssen Biotech, Inc. |
ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
|
|
WO2013184912A2
(en)
|
2012-06-06 |
2013-12-12 |
Oncomed Pharmaceuticals, Inc. |
Binding agents that modulate the hippo pathway and uses thereof
|
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
AU2013285355A1
(en)
|
2012-07-06 |
2015-01-29 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
JP6335896B2
(ja)
|
2012-07-13 |
2018-05-30 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
Ｒｓｐｏ３結合剤およびその使用法
|
|
DK2877493T3
(en)
|
2012-07-25 |
2018-06-14 |
Celldex Therapeutics Inc |
ANTI-KIT ANTIBODIES AND APPLICATIONS THEREOF
|
|
DK3489261T3
(da)
|
2012-08-24 |
2020-12-14 |
Univ California |
Antistoffer og vacciner til anvendelse ved behandling af ror1-cancere og hæmning af metastase
|
|
DK2900694T3
(en)
|
2012-09-27 |
2018-11-19 |
Merus Nv |
BISPECIFIC IGG ANTIBODIES AS T-CELL ACTIVATORS
|
|
US10087250B2
(en)
|
2012-10-08 |
2018-10-02 |
Roche Glycart Ag |
Fc-free antibodies comprising two fab-fragments and methods of use
|
|
WO2014062659A2
(en)
*
|
2012-10-15 |
2014-04-24 |
Oncomed Pharmaceuticals, Inc. |
Methods of treating ocular diseases
|
|
AU2013337811A1
(en)
|
2012-10-31 |
2015-05-14 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a DLL4 antagonist
|
|
EP2727941A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Method for the production of multispecific antibodies
|
|
EP2727943A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Trispecific antibodies against human EGFR, HER2 and HER3
|
|
WO2014067642A1
(en)
|
2012-11-05 |
2014-05-08 |
Mab Discovery Gmbh |
Method for the production of multispecific antibodies
|
|
EP2727942A1
(en)
|
2012-11-05 |
2014-05-07 |
MAB Discovery GmbH |
Bispecific antibodies against human EGFR, HER2, and HER3
|
|
TW201431880A
(zh)
|
2012-11-07 |
2014-08-16 |
Pfizer |
抗切口３（ａｎｔｉ－ｎｏｔｃｈ３）抗體及抗體－藥物共軛體
|
|
US20170275367A1
(en)
|
2012-11-21 |
2017-09-28 |
Janssen Biotech, Inc. |
Bispecific EGFR/C-Met Antibodies
|
|
CN104870476B
(zh)
*
|
2012-11-21 |
2018-04-13 |
药物抗体公司 |
靶向vegfr‑2和dll4的双靶向抗体及包含它的药物组合物
|
|
HUE041499T2
(hu)
|
2012-11-21 |
2019-05-28 |
Janssen Biotech Inc |
Bispecifikus EGFR/C-MET-ellenanyagok
|
|
KR102545617B1
(ko)
|
2012-11-28 |
2023-06-20 |
자임워크스 비씨 인코포레이티드 |
가공된 면역글로불린 중쇄-경쇄 쌍 및 이들의 용도
|
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
|
HK1210964A1
(en)
|
2012-12-04 |
2016-05-13 |
Oncomed Pharmaceuticals, Inc. |
Immunotherapy with binding agents
|
|
US20150353636A1
(en)
|
2013-01-10 |
2015-12-10 |
Genmab B.V. |
Human igg1 fc region variants and uses thereof
|
|
US10047163B2
(en)
|
2013-02-08 |
2018-08-14 |
Abbvie Stemcentrx Llc |
Multispecific constructs
|
|
EP3617220B1
(en)
|
2013-02-12 |
2021-03-24 |
Bristol-Myers Squibb Company |
High ph protein refolding methods
|
|
ES2813501T3
(es)
|
2013-02-12 |
2021-03-24 |
Bristol Myers Squibb Co |
Métodos de replegado de proteínas basados en filtración de flujo tangencial
|
|
KR20180023035A
(ko)
|
2013-02-26 |
2018-03-06 |
로슈 글리카트 아게 |
이중특이적 t 세포 활성화 항원 결합 분자
|
|
WO2014131694A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
WO2014141064A1
(en)
|
2013-03-13 |
2014-09-18 |
Novartis Ag |
Notch2 binding molecules for treating respiratory diseases
|
|
US9168300B2
(en)
|
2013-03-14 |
2015-10-27 |
Oncomed Pharmaceuticals, Inc. |
MET-binding agents and uses thereof
|
|
JP2016512533A
(ja)
*
|
2013-03-14 |
2016-04-28 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
Ｍｅｔ結合剤およびその使用
|
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res Munich Gmbh |
Moléculas de unión para bcma y cd3
|
|
CA2906526C
(en)
|
2013-03-15 |
2022-12-06 |
Ellen Chi |
Interferon alpha and omega antibody antagonists
|
|
JP2016515544A
(ja)
|
2013-03-18 |
2016-05-30 |
バイオセルオーエックス プロダクツ ビー．ブイ． |
ヒト化抗ｃｄ１３４（ｏｘ４０）抗体およびその使用
|
|
UA118029C2
(uk)
|
2013-04-29 |
2018-11-12 |
Ф. Хоффманн-Ля Рош Аг |
Модифіковане антитіло, що зв'язується з людським fcrn, й способи його застосування
|
|
CN105164157B
(zh)
|
2013-04-29 |
2024-05-28 |
豪夫迈·罗氏有限公司 |
Fc-受体结合的修饰的非对称抗体及使用方法
|
|
PE20151925A1
(es)
|
2013-04-29 |
2015-12-26 |
Hoffmann La Roche |
Anticuerpos anti-igf-1r con abolicion de la union al fcrn y su utilizacion en el tratamiento de enfermedades oculares vasculares
|
|
IL311371B2
(en)
|
2013-07-05 |
2024-09-01 |
Genmab As |
CD3 antibodies of human origin or chimeras
|
|
KR101673389B1
(ko)
*
|
2013-07-09 |
2016-11-08 |
에이비엘바이오 주식회사 |
Dll4와 vegf에 특이적으로 결합하는 신규 이중표적 단백질 및 이의 용도
|
|
US11305012B2
(en)
|
2013-09-24 |
2022-04-19 |
Medimmune, Llc |
Binding molecules specific for HER3 and uses thereof
|
|
CN105764922B
(zh)
|
2013-09-27 |
2020-07-17 |
中外制药株式会社 |
多肽异源多聚体的制备方法
|
|
KR20160044060A
(ko)
*
|
2013-10-11 |
2016-04-22 |
에프. 호프만-라 로슈 아게 |
다중특이적 도메인 교환된 통상의 가변 경쇄 항체
|
|
EA034655B1
(ru)
|
2013-11-06 |
2020-03-03 |
Янссен Байотек, Инк. |
Антитела к ccl17
|
|
CN106029696B
(zh)
|
2013-12-17 |
2020-07-28 |
基因泰克公司 |
抗cd3抗体及使用方法
|
|
SG11201605044RA
(en)
|
2013-12-20 |
2016-07-28 |
Hoffmann La Roche |
HUMANIZED ANTI-Tau(pS422) ANTIBODIES AND METHODS OF USE
|
|
RU2693438C2
(ru)
|
2014-01-03 |
2019-07-02 |
Ф. Хоффманн-Ля Рош Аг |
Биспецифичные антитела против гаптена/против рецептора гематоэнцефалического барьера, их комплексы и их применение в качестве челноков гематоэнцефалического барьера
|
|
JP6557664B2
(ja)
|
2014-01-06 |
2019-08-07 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
一価の血液脳関門シャトルモジュール
|
|
RU2727639C2
(ru)
|
2014-01-15 |
2020-07-22 |
Ф.Хоффманн-Ля Рош Аг |
Варианты fc-области с модифицированной способностью связываться с fcrn и с сохраненной способностью связываться с белком а
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
|
US10844127B2
(en)
|
2014-02-28 |
2020-11-24 |
Merus N.V. |
Antibodies that bind EGFR and ErbB3
|
|
DK3805268T3
(da)
|
2014-02-28 |
2025-01-20 |
Merus Nv |
Antistof, der binder erbb-2 og erbb-3
|
|
KR102442436B1
(ko)
|
2014-03-14 |
2022-09-15 |
노파르티스 아게 |
Lag-3에 대한 항체 분자 및 그의 용도
|
|
JP2017513818A
(ja)
|
2014-03-15 |
2017-06-01 |
ノバルティス アーゲー |
キメラ抗原受容体を使用する癌の処置
|
|
EP3126389B1
(en)
|
2014-04-02 |
2024-10-23 |
F. Hoffmann-La Roche AG |
Method for detecting multispecific antibody light chain mispairing
|
|
UA117289C2
(uk)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
|
WO2015149721A1
(en)
*
|
2014-04-04 |
2015-10-08 |
Crown Bioscience, Inc.(Taicang) |
Methods for determining responsiveness to mek/erk inhibitors
|
|
KR102568808B1
(ko)
|
2014-04-07 |
2023-08-18 |
추가이 세이야쿠 가부시키가이샤 |
면역활성화 항원 결합 분자
|
|
US10745490B2
(en)
|
2014-04-11 |
2020-08-18 |
Celldex Therapeutics, Inc. |
Anti-ErbB antibodies and methods of use thereof
|
|
WO2015171822A1
(en)
|
2014-05-06 |
2015-11-12 |
Genentech, Inc. |
Production of heteromultimeric proteins using mammalian cells
|
|
AU2015260230A1
(en)
|
2014-05-13 |
2016-11-17 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
|
CN113908269A
(zh)
|
2014-05-23 |
2022-01-11 |
塞尔德克斯医疗公司 |
嗜酸性粒细胞或肥大细胞相关病症的治疗
|
|
BR112016027888A2
(pt)
|
2014-05-28 |
2017-10-24 |
Zymeworks Inc |
construto de polipeptídeo de ligação ao antígeno isolado, polinucleotídeo isolado ou um conjunto de polinucleotídeos isolados, vetor ou conjunto de vetores, célula isolada, composição farmacêutica, uso do construto, método para tratar um sujeito com uma doença ou distúrbio, método para obter um construto, método para preparar um construto, meio de armazenamento legível por computador, método para produzir um construto de polipeptídeo de ligação com antígeno bi-específico e método para preparar um construto de polipeptídeo de ligação com antígeno isolado
|
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
|
BR112016029935A2
(pt)
|
2014-06-26 |
2017-10-31 |
Hoffmann La Roche |
?anticorpos anti-brdu, complexo, formulação farmacêutica e uso de anticorpo?
|
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
|
CN114621347A
(zh)
|
2014-07-11 |
2022-06-14 |
根马布股份公司 |
结合axl的抗体
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
US10174095B2
(en)
|
2014-07-21 |
2019-01-08 |
Novartis Ag |
Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
SG11201700416TA
(en)
|
2014-07-21 |
2017-02-27 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
EP3174546B1
(en)
|
2014-07-31 |
2019-10-30 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
PE20211533A1
(es)
|
2014-08-04 |
2021-08-16 |
Hoffmann La Roche |
Moleculas biespecificas de unon a antigeno activadoras de celulas t
|
|
AU2015301460B2
(en)
|
2014-08-14 |
2021-04-08 |
Novartis Ag |
Treatment of cancer using GFR alpha-4 chimeric antigen receptor
|
|
DK3183268T3
(da)
|
2014-08-19 |
2020-05-11 |
Univ Pennsylvania |
Behandling af cancer ved anvendelse af en cd123-kimær antigenreceptor
|
|
SMT202000253T1
(it)
|
2014-09-05 |
2020-07-08 |
Janssen Pharmaceutica Nv |
Agenti leganti cd123 e loro usi
|
|
PH12017500442B1
(en)
|
2014-09-09 |
2023-05-24 |
Janssen Biotech Inc |
Combination therapies with anti-cd38 antibodies
|
|
WO2016040895A1
(en)
|
2014-09-12 |
2016-03-17 |
xxTHE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
Wnt signaling agonist molecules
|
|
TW201628648A
(zh)
|
2014-09-16 |
2016-08-16 |
安可美德藥物股份有限公司 |
纖維變性疾病之治療
|
|
KR20210149228A
(ko)
|
2014-09-17 |
2021-12-08 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
|
WO2016055592A1
(en)
|
2014-10-09 |
2016-04-14 |
Engmab Ag |
Bispecific antibodies against cd3epsilon and ror1
|
|
EA201790834A1
(ru)
|
2014-10-14 |
2018-01-31 |
Новартис Аг |
Молекулы антител к pd-l1 и их применение
|
|
PT3212233T
(pt)
|
2014-10-31 |
2020-07-16 |
Oncomed Pharm Inc |
Terapia combinada para o tratamento de doenças
|
|
EP3842453A1
(en)
|
2014-11-06 |
2021-06-30 |
F. Hoffmann-La Roche AG |
Fc-region variants with modified fcrn- and protein a-binding properties
|
|
HRP20191766T1
(hr)
|
2014-11-06 |
2019-12-27 |
F. Hoffmann - La Roche Ag |
Varijante fc regije s modificiranim vezanjem na neonatalni fc receptor (fcrn) i postupci primjene
|
|
LT3221357T
(lt)
|
2014-11-20 |
2020-08-25 |
F. Hoffmann-La Roche Ag |
Bendros lengvosios grandinės ir naudojimo būdai
|
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
HRP20201928T1
(hr)
|
2014-11-20 |
2021-02-05 |
F. Hoffmann - La Roche Ag |
Kombinirana terapija bispecifičnom antigen vezujućom molekulom koja aktivira t-stanice, za cd3 i folatni receptor 1 (folr1), i antagonistom vezivanja osi pd-1
|
|
MX2017006571A
(es)
|
2014-11-20 |
2017-09-29 |
Hoffmann La Roche |
Moleculas de union a antigeno biespecificas activadoras de celulas t.
|
|
EP3227332B1
(en)
|
2014-12-03 |
2019-11-06 |
F.Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
IL307913A
(en)
|
2014-12-04 |
2023-12-01 |
Janssen Biotech Inc |
Anti-CD38 antibodies for the treatment of acute myeloid leukemia
|
|
US10865253B2
(en)
|
2014-12-19 |
2020-12-15 |
Genmab A/S |
Rodent bispecific heterodimeric proteins
|
|
US11142587B2
(en)
|
2015-04-01 |
2021-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide hetero-oligomer
|
|
HUE059218T2
(hu)
|
2015-04-08 |
2022-11-28 |
Novartis Ag |
CD20-terápiák, CD22-terápiák és kombinációs terápiák CD19 kiméra antigénreceptort (CAR-t) expresszáló sejttel
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
KR20240093883A
(ko)
*
|
2015-04-28 |
2024-06-24 |
자임워크스 비씨 인코포레이티드 |
변형된 항원 결합 폴리펩티드 작제물 및 이의 용도
|
|
KR20180002782A
(ko)
|
2015-05-06 |
2018-01-08 |
얀센 바이오테크 인코포레이티드 |
전립선 특이적 막 항원(psma) 이중특이성 결합제 및 그의 용도
|
|
CN108136218B
(zh)
|
2015-05-20 |
2022-12-13 |
詹森生物科技公司 |
用于治疗轻链淀粉样变性及其它cd38阳性血液恶性肿瘤的抗cd38抗体
|
|
PE20240218A1
(es)
|
2015-06-16 |
2024-02-16 |
Genentech Inc |
Anticuerpos madurados por afinidad y humanizados para fcrh5
|
|
PE20181323A1
(es)
|
2015-06-22 |
2018-08-14 |
Janssen Biotech Inc |
Terapias de combinacion para enfermedades malignas hematologicas con anticuerpos anti-cd38 e inhibidores de survivina
|
|
WO2016207245A1
(en)
|
2015-06-24 |
2016-12-29 |
F. Hoffmann-La Roche Ag |
Humanized anti-tau(ps422) antibodies and methods of use
|
|
PT3313441T
(pt)
|
2015-06-24 |
2024-05-07 |
Janssen Biotech Inc |
Modulação imunitária e tratamento de tumores sólidos com anticorpos que se ligam especificamente a cd38
|
|
JP7010811B2
(ja)
|
2015-07-10 |
2022-02-10 |
メルス ナムローゼ フェンノートシャップ |
ヒトｃｄ３結合抗体
|
|
PT3319993T
(pt)
|
2015-07-10 |
2020-04-22 |
Genmab As |
Conjugados de anticorpo-fármaco específicos de axl para tratamento de cancro
|
|
BR112018000696A2
(pt)
|
2015-07-15 |
2018-09-18 |
Genmab As |
?anticorpo, métodos para reduzir e para aumentar a afinidade de ligação de um anticorpo que se liga ao cd3 humano, para tratar e para diagnosticar uma doença, para produzir um anticorpo e para detectar a presença de antígeno de cd3, construto de ácido nucleico, vetor de expressão, célula hospedeira, composição, e, kit?
|
|
ES2878188T3
(es)
|
2015-07-29 |
2021-11-18 |
Novartis Ag |
Terapias de combinación que comprenden moléculas de anticuerpos contra LAG-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
MY188405A
(en)
|
2015-08-05 |
2021-12-08 |
Janssen Biotech Inc |
Anti-cd154 antibodies and methods of using them
|
|
MX2018001566A
(es)
|
2015-08-07 |
2019-04-25 |
Imaginab Inc |
Construcciones de union a antigeno para moleculas diana.
|
|
JP2018525005A
(ja)
|
2015-08-17 |
2018-09-06 |
ヤンセン ファーマシューティカ エヌ．ベー． |
抗ｂｃｍａ抗体、ｂｃｍａ及びｃｄ３に結合する二重特異性抗原結合分子、並びにそれらの使用
|
|
CN107106682B
(zh)
|
2015-08-26 |
2021-05-25 |
比森医疗股份有限公司 |
多特异性抗体平台和相关方法
|
|
EP3344278A4
(en)
*
|
2015-09-04 |
2019-01-23 |
The California Institute for Biomedical Research |
INSULIN-IMMUNOGLOBULIN FUSION PROTEINS
|
|
EP3352760A4
(en)
|
2015-09-21 |
2019-03-06 |
Aptevo Research and Development LLC |
CD3-BINDING POLYPEPTIDES
|
|
ES2968074T3
(es)
|
2015-09-23 |
2024-05-07 |
Mereo Biopharma 5 Inc |
Anticuerpo bi-específico anti-VEGF/DLL4 para su uso en el tratamiento del cáncer de ovario resistente al platino
|
|
JP2018529351A
(ja)
|
2015-09-30 |
2018-10-11 |
ヤンセン バイオテツク，インコーポレーテツド |
ヒトｃｄ４０に特異的に結合するアンタゴニスト抗体及び使用方法
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
IL257110B
(en)
|
2015-10-02 |
2022-09-01 |
Hoffmann La Roche |
Bispecific antibodies specific against pd1 and tim3
|
|
EP3356409A2
(en)
|
2015-10-02 |
2018-08-08 |
H. Hoffnabb-La Roche Ag |
Bispecific t cell activating antigen binding molecules
|
|
CN108139394B
(zh)
|
2015-10-02 |
2020-10-30 |
豪夫迈·罗氏有限公司 |
用于确定同时结合的基于细胞的fret测定法
|
|
EP3913000A1
(en)
|
2015-10-02 |
2021-11-24 |
F. Hoffmann-La Roche AG |
Bispecific anti-cd19xcd3 t cell activating antigen binding molecules
|
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
|
WO2017055395A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
|
EP3150637A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
|
BR112018000835A2
(pt)
|
2015-10-02 |
2018-09-11 |
Hoffmann La Roche |
molécula, um ou mais polinucleotídeos, um ou mais vetores, célula, método de produção da molécula, composição, uso da molécula, método de tratamento de uma doença e método para induzir a lise de uma célula-alvo
|
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
|
AR106365A1
(es)
|
2015-10-02 |
2018-01-10 |
Hoffmann La Roche |
Moléculas biespecíficas de unión a antígeno activadoras de células t
|
|
CA3002957A1
(en)
|
2015-10-23 |
2017-04-27 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Binding molecules that inhibit cancer growth
|
|
WO2017072210A1
(en)
|
2015-10-29 |
2017-05-04 |
F. Hoffmann-La Roche Ag |
Anti-variant fc-region antibodies and methods of use
|
|
JP2018534933A
(ja)
|
2015-11-02 |
2018-11-29 |
ヤンセン ファーマシューティカ エヌ．ベー． |
抗ｉｌ１ｒａｐ抗体、ｉｌ１ｒａｐとｃｄ３を結合する二重特異性抗原結合分子、及びその使用
|
|
MA43186B1
(fr)
|
2015-11-03 |
2022-03-31 |
Janssen Biotech Inc |
Anticorps se liant spécifiquement à pd-1 et leurs utilisations
|
|
HUE053366T2
(hu)
|
2015-11-03 |
2021-06-28 |
Janssen Biotech Inc |
Szubkután anti-CD38-ellenanyag-készítmények és alkalmazásuk
|
|
WO2017086367A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するｔ細胞リダイレクト抗原結合分子を用いた併用療法
|
|
US11649293B2
(en)
|
2015-11-18 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for enhancing humoral immune response
|
|
WO2017093447A1
(en)
|
2015-12-01 |
2017-06-08 |
Genmab B.V. |
Anti-death receptor antibodies and methods of use thereof
|
|
ES2901794T3
(es)
|
2015-12-09 |
2022-03-23 |
Hoffmann La Roche |
Anticuerpo anti-CD20 de tipo II para reducir la formación de anticuerpos antifármaco
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
CN108697794A
(zh)
|
2015-12-17 |
2018-10-23 |
诺华股份有限公司 |
C-met抑制剂和抗pd-1抗体分子的组合及其用途
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
MA44072A
(fr)
|
2015-12-17 |
2018-10-24 |
Janssen Biotech Inc |
Anticorps se liant spécifiquement à hla-dr et leurs utilisations
|
|
EP4643874A2
(en)
|
2015-12-22 |
2025-11-05 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
WO2017110980A1
(ja)
|
2015-12-25 |
2017-06-29 |
中外製薬株式会社 |
増強された活性を有する抗体及びその改変方法
|
|
US11649262B2
(en)
|
2015-12-28 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for promoting efficiency of purification of Fc region-containing polypeptide
|
|
KR20180097615A
(ko)
|
2016-01-08 |
2018-08-31 |
에프. 호프만-라 로슈 아게 |
Pd-1 축 결합 길항물질 및 항-cea/항-cd3 이중특이성 항체를 사용하는 cea-양성 암의 치료 방법
|
|
EP3405492B1
(en)
|
2016-01-21 |
2020-10-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
CN109073635A
(zh)
*
|
2016-01-25 |
2018-12-21 |
豪夫迈·罗氏有限公司 |
用于测定t细胞依赖性双特异性抗体的方法
|
|
US20200281973A1
(en)
|
2016-03-04 |
2020-09-10 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
MX2018010988A
(es)
|
2016-03-14 |
2019-01-21 |
Chugai Pharmaceutical Co Ltd |
Farmaco terapeutico que induce lesion celular para usarse en terapia de cancer.
|
|
WO2017165464A1
(en)
|
2016-03-21 |
2017-09-28 |
Elstar Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
|
RS64266B1
(sr)
|
2016-03-22 |
2023-07-31 |
Hoffmann La Roche |
Bispecifični molekul koji aktivira t ćeliju koji se aktivira proteazom
|
|
WO2017165683A1
(en)
|
2016-03-23 |
2017-09-28 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
SI3443096T1
(sl)
|
2016-04-15 |
2023-07-31 |
Novartis Ag |
Sestavki in postopki za selektivno izražanje himerni antigenskih receptorjev
|
|
MX2018012648A
(es)
|
2016-04-28 |
2019-01-30 |
Chugai Pharmaceutical Co Ltd |
Preparaciones que contienen anticuerpos.
|
|
EP3889175A1
(en)
|
2016-05-02 |
2021-10-06 |
F. Hoffmann-La Roche AG |
The contorsbody - a single chain target binder
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
AU2018276419A1
(en)
|
2016-06-02 |
2019-10-17 |
F. Hoffmann-La Roche Ag |
Type II anti-CD20 antibody and anti-CD20/CD3 bispecific antibody for treatment of cancer
|
|
WO2017210617A2
(en)
|
2016-06-02 |
2017-12-07 |
Porter, David, L. |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
JP7109007B2
(ja)
|
2016-06-27 |
2022-07-29 |
ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア |
がん治療の組み合わせ
|
|
EP3474895A1
(en)
|
2016-06-28 |
2019-05-01 |
UMC Utrecht Holding B.V. |
TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38
|
|
EP3478717B1
(en)
|
2016-07-04 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Novel antibody format
|
|
MA45672A
(fr)
|
2016-07-14 |
2019-05-22 |
Biontech Ag |
Anticorps multispécifiques dirigés contre cd40 et cd137
|
|
US20190336504A1
(en)
|
2016-07-15 |
2019-11-07 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
TWI781108B
(zh)
|
2016-07-20 |
2022-10-21 |
比利時商健生藥品公司 |
抗ｇｐｒｃ５ｄ抗體、結合ｇｐｒｃ５ｄ與ｃｄ３之雙特異性抗原結合分子及其用途
|
|
CN110214150A
(zh)
|
2016-07-28 |
2019-09-06 |
诺华股份有限公司 |
嵌合抗原受体和pd-1抑制剂的组合疗法
|
|
JP2019527696A
(ja)
|
2016-08-01 |
2019-10-03 |
ノバルティス アーゲー |
プロｍ２マクロファージ分子の阻害剤と組み合わせてキメラ抗原受容体を用いる癌の処置
|
|
US10669344B2
(en)
|
2016-08-12 |
2020-06-02 |
Janssen Biotech, Inc. |
Engineered antibodies and other Fc-domain containing molecules with enhanced agonism and effector functions
|
|
MA45941A
(fr)
|
2016-08-12 |
2019-06-19 |
Janssen Biotech Inc |
Anticorps de membres de la superfamille anti-tnfr modifiés par fc ayant une activité agoniste améliorée et leurs procédés d'utilisation
|
|
JP7022123B2
(ja)
|
2016-09-30 |
2022-02-17 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｃｄ３に対する二重特異性抗体
|
|
WO2018060035A1
(en)
|
2016-09-30 |
2018-04-05 |
F. Hoffmann-La Roche Ag |
Spr-based dual-binding assay for the functional analysis of multispecific molecules
|
|
CA3039646A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
JOP20190095A1
(ar)
|
2016-10-27 |
2019-04-28 |
Janssen Pharmaceutica Nv |
مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y
|
|
US20190276549A1
(en)
|
2016-11-01 |
2019-09-12 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
|
US11466094B2
(en)
|
2016-11-15 |
2022-10-11 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
|
US11702480B2
(en)
*
|
2016-11-18 |
2023-07-18 |
The Regents Of The University Of California |
Engineered antibodies and uses thereof
|
|
AU2017363309A1
(en)
|
2016-11-23 |
2019-07-11 |
Bioverativ Therapeutics Inc. |
Mono- and bispecific antibodies binding to coagulation factor IX and coagulation factor X
|
|
EP3574005B1
(en)
|
2017-01-26 |
2021-12-15 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
WO2018147960A1
(en)
|
2017-02-08 |
2018-08-16 |
Imaginab, Inc. |
Extension sequences for diabodies
|
|
CA3053222A1
(en)
|
2017-02-10 |
2018-08-16 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
US12054544B2
(en)
|
2017-02-24 |
2024-08-06 |
Chugai Seiyaku Kabushiki Kaisha |
Compositions comprising antigen-binding molecules
|
|
EP3589650A1
(en)
|
2017-03-02 |
2020-01-08 |
Novartis AG |
Engineered heterodimeric proteins
|
|
LT3592769T
(lt)
|
2017-03-09 |
2024-08-26 |
Genmab A/S |
Antikūnai, atpažįstantys pd-l1
|
|
CN110402253B
(zh)
|
2017-03-10 |
2024-01-05 |
豪夫迈·罗氏有限公司 |
用于生产多特异性抗体的方法
|
|
WO2018178396A1
(en)
|
2017-03-31 |
2018-10-04 |
Genmab Holding B.V. |
Bispecific anti-cd37 antibodies, monoclonal anti-cd37 antibodies and methods of use thereof
|
|
EP3600413A1
(en)
|
2017-03-31 |
2020-02-05 |
Merus N.V. |
Erbb-2 and erbb3 binding bispecific antibodies for use in the treatment f cells that have an nrg1 fusion gene
|
|
AU2018247767B2
(en)
|
2017-04-03 |
2025-01-30 |
F. Hoffmann-La Roche Ag |
Antibodies binding to STEAP-1
|
|
EP3606960A1
(en)
|
2017-04-03 |
2020-02-12 |
Oncologie, Inc. |
Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents
|
|
WO2018184965A1
(en)
|
2017-04-03 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
|
KR102461885B1
(ko)
|
2017-04-03 |
2022-11-03 |
에프. 호프만-라 로슈 아게 |
항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
|
|
EP4516809A3
(en)
|
2017-04-05 |
2025-09-03 |
F. Hoffmann-La Roche AG |
Bispecific antibodies specifically binding to pd1 and lag3
|
|
CN113527499A
(zh)
*
|
2017-04-09 |
2021-10-22 |
轩竹生物科技有限公司 |
有共同轻链的双互补位和多互补位抗体和使用方法
|
|
BR112019021411A2
(pt)
|
2017-04-13 |
2020-05-05 |
Hoffmann La Roche |
métodos para tratar ou retardar a progressão do câncer e para melhorar a função, usos de um imunoconjugado, de um agonista, de um antagonista, composições, kit e invenção
|
|
US20200179511A1
(en)
|
2017-04-28 |
2020-06-11 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
CN108866635B
(zh)
*
|
2017-05-09 |
2021-11-26 |
安升（上海）医药科技有限公司 |
多特异性蛋白药物及其文库、以及制备方法和应用
|
|
KR102744809B1
(ko)
|
2017-05-17 |
2024-12-23 |
메뤼스 엔.페. |
유방암 치료를 위한 ErbB-2/ErbB-3 이중특이적 항체와 내분비 치료의 조합
|
|
EP3630836A1
(en)
|
2017-05-31 |
2020-04-08 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
MX2019014577A
(es)
|
2017-06-05 |
2020-07-29 |
Janssen Biotech Inc |
Anticuerpos que se unen especificamente a pd-1 y metodos de uso.
|
|
AU2018281045A1
(en)
|
2017-06-05 |
2019-12-12 |
Janssen Biotech, Inc. |
Engineered multispecific antibodies and other multimeric proteins with asymmetrical CH2-CH3 region mutations
|
|
JP2020522543A
(ja)
|
2017-06-07 |
2020-07-30 |
ゲンマブ ビー．ブイ． |
変異ＩｇＧ六量体に基づく治療用抗体
|
|
CN110785187B
(zh)
|
2017-06-22 |
2024-04-05 |
诺华股份有限公司 |
针对cd73的抗体分子及其用途
|
|
US20200223924A1
(en)
|
2017-06-27 |
2020-07-16 |
Novartis Ag |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
|
AR112603A1
(es)
|
2017-07-10 |
2019-11-20 |
Lilly Co Eli |
Anticuerpos biespecíficos inhibidores de punto de control
|
|
MX2020000342A
(es)
|
2017-07-11 |
2020-08-17 |
Compass Therapeutics Llc |
Anticuerpos agonistas que se unen a cd137 humano y sus usos.
|
|
IL319798A
(en)
|
2017-07-20 |
2025-05-01 |
Novartis Ag |
ANTI-LAG-3 Antibody Dosage Regimens and Their Uses
|
|
CN111406067B
(zh)
|
2017-08-04 |
2022-11-08 |
健玛保 |
与pd-l1和cd137结合的结合剂及其用途
|
|
PL3665198T3
(pl)
|
2017-08-09 |
2025-06-09 |
Merus N.V. |
Przeciwciała wiążące egfr i cmet
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
CN111108202B
(zh)
|
2017-09-29 |
2024-10-22 |
中外制药株式会社 |
具有凝血因子viii(fviii)辅因子功能替代活性的多特异性抗原结合分子及含有所述分子作为活性成分的药物制剂
|
|
JP7450535B2
(ja)
|
2017-10-20 |
2024-03-15 |
エフ． ホフマン－ラ ロシュ アーゲー |
単一特異性抗体から多重特異性抗体を生成させるための方法
|
|
TWI832824B
(zh)
|
2017-10-30 |
2024-02-21 |
瑞士商赫孚孟拉羅股份公司 |
自單特異性抗體於活體內產生多特異性抗體之方法
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
WO2019086394A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
The compbody - a multivalent target binder
|
|
EP3703746A1
(en)
|
2017-11-01 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Novel tnf family ligand trimer-containing antigen binding molecules
|
|
IL272747B2
(en)
|
2017-11-01 |
2025-04-01 |
Hoffmann La Roche |
Bispecific antibodies 1 + 2
|
|
SG11202003833TA
(en)
|
2017-11-01 |
2020-05-28 |
Chugai Pharmaceutical Co Ltd |
Antibody variant and isoform with lowered biological activity
|
|
PL3704146T3
(pl)
|
2017-11-01 |
2022-03-07 |
F. Hoffmann-La Roche Ag |
Przeciwciało Contorsbody trifab
|
|
MX2020004756A
(es)
|
2017-11-16 |
2020-08-20 |
Novartis Ag |
Terapias de combinacion.
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
JP6522727B2
(ja)
*
|
2017-12-15 |
2019-05-29 |
矢崎総業株式会社 |
メッキ繊維及びワイヤハーネス
|
|
EP3731867A4
(en)
|
2017-12-19 |
2022-04-06 |
Surrozen Operating, Inc. |
Anti-lrp5/6 antibodies and methods of use
|
|
EP3732201A4
(en)
|
2017-12-19 |
2022-04-20 |
Surrozen Operating, Inc. |
WNT SURROGATES AND THEIR USES
|
|
US12006368B2
(en)
|
2017-12-19 |
2024-06-11 |
Surrozen Operating, Inc. |
Anti-frizzled antibodies and methods of use
|
|
TWI805665B
(zh)
|
2017-12-21 |
2023-06-21 |
瑞士商赫孚孟拉羅股份公司 |
結合hla-a2/wt1之抗體
|
|
JP7074859B2
(ja)
|
2017-12-22 |
2022-05-24 |
エフ．ホフマン－ラ ロシュ アーゲー |
疎水性相互作用クロマトグラフィーによる軽鎖誤対合抗体変種の枯渇の方法
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
JP2021510740A
(ja)
|
2018-01-24 |
2021-04-30 |
ゲンマブ ビー．ブイ． |
ポリペプチド変種およびそれらの用途
|
|
AU2019215031B2
(en)
|
2018-01-31 |
2025-10-09 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
CN111699004A
(zh)
|
2018-02-06 |
2020-09-22 |
豪夫迈·罗氏有限公司 |
眼科疾病的治疗
|
|
CN118772288A
(zh)
|
2018-02-08 |
2024-10-15 |
豪夫迈·罗氏有限公司 |
双特异性抗原结合分子和使用方法
|
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
|
JP7466442B2
(ja)
|
2018-02-14 |
2024-04-12 |
中外製薬株式会社 |
抗原結合分子および組合せ
|
|
CR20250348A
(es)
|
2018-03-12 |
2025-09-23 |
Genmab As |
ANTICUERPOS QUE SE UNEN A 5T4 (Divisional 2020-463)
|
|
EP3765516A2
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
WO2019211472A1
(en)
|
2018-05-03 |
2019-11-07 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
|
CN108752478B
(zh)
*
|
2018-05-03 |
2021-05-25 |
沣潮医药科技（上海）有限公司 |
全人源抗人EGFR和Notch2/3多特异性抗体、其制备方法及用途
|
|
CN120285175A
(zh)
|
2018-05-16 |
2025-07-11 |
詹森生物科技公司 |
治疗癌症并增强t细胞重定向治疗剂的功效的方法
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
CN112384534A
(zh)
|
2018-05-21 |
2021-02-19 |
指南针制药有限责任公司 |
用于增强nk细胞对靶细胞的杀死的组合物和方法
|
|
US11866499B2
(en)
|
2018-05-24 |
2024-01-09 |
Janssen Biotech, Inc. |
Monospecific and multispecific anti-TMEFF2 antibodies and their uses
|
|
JOP20190116A1
(ar)
|
2018-05-24 |
2019-11-24 |
Janssen Biotech Inc |
الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها
|
|
EP3802608B1
(en)
|
2018-05-24 |
2025-04-30 |
Janssen Biotech, Inc. |
Anti-cd3 antibodies and uses thereof
|
|
AU2019274657A1
(en)
|
2018-05-24 |
2020-12-10 |
Janssen Biotech, Inc. |
PSMA binding agents and uses thereof
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
KR20210016448A
(ko)
|
2018-06-01 |
2021-02-15 |
컴퓨젠 엘티디. |
항-pvrig/항-tigit 이중특이적 항체 및 사용 방법
|
|
MY208825A
(en)
|
2018-06-13 |
2025-05-30 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
|
EP3810269A2
(en)
|
2018-06-19 |
2021-04-28 |
Atarga, LLC |
Antibody molecules to complement component 5 and uses thereof
|
|
JP7513530B2
(ja)
|
2018-06-22 |
2024-07-09 |
ジェンマブ ホールディング ビー．ブイ． |
抗ｃｄ３７抗体および抗ｃｄ２０抗体、組成物、ならびにそれらの使用方法
|
|
EP3818083A2
(en)
|
2018-07-03 |
2021-05-12 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
MA53123A
(fr)
|
2018-07-13 |
2021-05-19 |
Genmab As |
Thérapie à médiation par trogocytose utilisant des anticorps cd38
|
|
KR20210031932A
(ko)
|
2018-07-13 |
2021-03-23 |
젠맵 에이/에스 |
Cd38 항체의 변이체 및 그의 용도
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
JP7523349B2
(ja)
|
2018-08-29 |
2024-07-26 |
中外製薬株式会社 |
抗体半分子、および抗体半分子のホモ二量体形成を抑制する方法
|
|
WO2020070313A1
(en)
|
2018-10-04 |
2020-04-09 |
Genmab Holding B.V. |
Pharmaceutical compositions comprising bispecific anti-cd37 antibodies
|
|
WO2020089051A1
(en)
|
2018-10-29 |
2020-05-07 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
|
WO2020094744A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
|
CN113166269B
(zh)
|
2018-11-13 |
2025-01-07 |
指南针制药有限责任公司 |
对抗检查点分子的多特异性结合构建体及其用途
|
|
CA3121699A1
(en)
|
2018-12-05 |
2020-06-11 |
Morphosys Ag |
Multispecific antigen-binding molecules
|
|
TWI874341B
(zh)
|
2018-12-18 |
2025-03-01 |
美商健生生物科技公司 |
產生異二聚體抗體之方法
|
|
BR112021011874A2
(pt)
|
2018-12-20 |
2021-09-08 |
Novartis Ag |
Regime de dosagem e combinação farmacêutica compreendendo derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona
|
|
KR20210106484A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
Hdm2-p53 상호작용 억제제와 bcl2 억제제의 조합 및 암 치료를 위한 이의 용도
|
|
US11672858B2
(en)
|
2018-12-21 |
2023-06-13 |
Hoffmann-La Roche Inc. |
Bispecific antibody molecules binding to CD3 and TYRP-1
|
|
IL319262A
(en)
|
2018-12-24 |
2025-04-01 |
Sanofi Sa |
Multispecific FAB pseudoproteins bind
|
|
CN113412123A
(zh)
|
2018-12-28 |
2021-09-17 |
豪夫迈·罗氏有限公司 |
用于免疫应答增强的患者的治疗性用途的肽-mhc-i-抗体融合蛋白
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
US20220153827A1
(en)
|
2019-01-15 |
2022-05-19 |
Janssen Biotech, Inc. |
Anti-TNF Antibody Compositions and Methods for the Treatment of Juvenile Idiopathic Arthritis
|
|
CN113597433B
(zh)
|
2019-01-18 |
2024-12-27 |
詹森生物科技公司 |
Gprc5d嵌合抗原受体以及表达这些受体的细胞
|
|
EA202192038A1
(ru)
|
2019-01-23 |
2021-10-05 |
Янссен Байотек, Инк. |
Композиции антител к фно для применения в способах лечения псориатического артрита
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CA3130628A1
(en)
|
2019-02-21 |
2020-08-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
|
|
CN119661722A
(zh)
|
2019-02-21 |
2025-03-21 |
马伦戈治疗公司 |
结合t细胞相关癌细胞的多功能分子及其用途
|
|
SG11202108955QA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Antibody molecules that bind to nkp30 and uses thereof
|
|
EP3927431A1
(en)
|
2019-02-21 |
2021-12-29 |
Marengo Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
AU2020224154B2
(en)
|
2019-02-21 |
2025-05-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US20220088075A1
(en)
|
2019-02-22 |
2022-03-24 |
The Trustees Of The University Of Pennsylvania |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
JOP20210233A1
(ar)
|
2019-02-26 |
2023-01-30 |
Janssen Biotech Inc |
علاجات مركبة وتطابق المريض مع الأجسام ثنائية النوعية المضادة لـ EGFR/c-Met.
|
|
MX2021010857A
(es)
|
2019-03-11 |
2021-12-15 |
Janssen Biotech Inc |
Anticuerpos biespecificos anti-v(beta17)/anti-cd123.
|
|
US12180271B2
(en)
|
2019-03-14 |
2024-12-31 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-TNF antibody compositions
|
|
JP7635137B2
(ja)
|
2019-03-14 |
2025-02-25 |
ヤンセン バイオテツク，インコーポレーテツド |
抗ｔｎｆ抗体組成物を産生するための方法
|
|
EP3938384A4
(en)
|
2019-03-14 |
2022-12-28 |
Janssen Biotech, Inc. |
PREPARATION PROCEDURES FOR THE PREPARATION OF ANTI-IL12/IL23 ANTIBODY COMPOSITIONS
|
|
EP3938392A1
(en)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech, Inc. |
Methods for producing anti-tnf antibody compositions
|
|
PH12021552414A1
(en)
|
2019-03-29 |
2022-07-25 |
Atarga Llc |
Anti fgf23 antibody
|
|
EP3948281A1
(en)
|
2019-03-29 |
2022-02-09 |
F. Hoffmann-La Roche AG |
Spr-based binding assay for the functional analysis of multivalent molecules
|
|
EP3947440A1
(en)
|
2019-03-29 |
2022-02-09 |
F. Hoffmann-La Roche AG |
Method for generating avid-binding multispecific antibodies
|
|
US11591395B2
(en)
|
2019-04-19 |
2023-02-28 |
Janssen Biotech, Inc. |
Methods of treating prostate cancer with an anti-PSMA/CD3 antibody
|
|
EP3959238A1
(en)
|
2019-04-25 |
2022-03-02 |
F. Hoffmann-La Roche AG |
Activatable therapeutic multispecific polypeptides with extended half-life
|
|
BR112021020843A2
(pt)
|
2019-04-25 |
2022-02-01 |
Hoffmann La Roche |
Conjunto de polipeptídeos precursores heterodiméricos, polipeptídeos heterodiméricos, métodos para gerar um polipeptídeo heterodimérico e para identificar um polipeptídeo heterodimérico multiespecífico, polipeptídeo heterodimérico multiespecífico, primeiro e segundo polipeptídeo precursor heterodimérico
|
|
WO2020216879A1
(en)
|
2019-04-25 |
2020-10-29 |
F. Hoffmann-La Roche Ag |
Therapeutic multispecific polypeptides activated by polypeptide chain exchange
|
|
KR20220017892A
(ko)
|
2019-05-08 |
2022-02-14 |
얀센 바이오테크 인코포레이티드 |
T세포 매개 면역의 조절을 위한 물질 및 방법
|
|
WO2020225456A1
(en)
|
2019-05-09 |
2020-11-12 |
Genmab B.V. |
Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
|
|
EP3969907B1
(en)
|
2019-05-13 |
2025-09-24 |
F. Hoffmann-La Roche AG |
Interference-suppressed pharmacokinetic immunoassay
|
|
MY208668A
(en)
|
2019-05-14 |
2025-05-23 |
Janssen Biotech Inc |
Combination therapies with bispecific anti-egfr/c-met antibodies and 3rd generation egfr tyrosine kinase inhibitors
|
|
WO2020245676A1
(en)
|
2019-06-03 |
2020-12-10 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions, and methods for the treatment of psoriatic arthritis
|
|
KR20220024460A
(ko)
*
|
2019-06-11 |
2022-03-03 |
안틀라 테라퓨틱스 아이엔씨. |
다가 fzd 및 wnt 결합 분자 및 이의 용도
|
|
CN114080451B
(zh)
|
2019-06-19 |
2024-03-22 |
豪夫迈·罗氏有限公司 |
通过使用Cre mRNA进行的靶向整合来产生蛋白质表达细胞的方法
|
|
ES3027485T3
(en)
|
2019-06-26 |
2025-06-16 |
Hoffmann La Roche |
Mammalian cell lines with sirt-1 gene knockout
|
|
JP2022538139A
(ja)
|
2019-07-02 |
2022-08-31 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
変異体インターロイキン－２及び抗ｃｄ８抗体を含む免疫複合体
|
|
CA3147044A1
(en)
|
2019-07-11 |
2021-01-14 |
Tavotek Biotherapeutics (Hong Kong) Limited |
Agents that interfere with thymic stromal lymphopoietin (tslp)-receptor signaling
|
|
JP2022540843A
(ja)
|
2019-07-12 |
2022-09-20 |
ヤンセン ファーマシューティカ エヌ．ベー． |
結合剤及びその使用
|
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
|
MX2022001049A
(es)
|
2019-07-26 |
2022-05-03 |
Janssen Biotech Inc |
Proteínas que comprenden dominios de unión al antígeno de la peptidasa 2 relacionada con la calicreína y sus usos.
|
|
CN114174338A
(zh)
|
2019-07-31 |
2022-03-11 |
豪夫迈·罗氏有限公司 |
与gprc5d结合的抗体
|
|
MX2022001156A
(es)
|
2019-07-31 |
2022-02-22 |
Hoffmann La Roche |
Anticuerpos que se fijan a gprc5d.
|
|
US11787875B2
(en)
|
2019-08-15 |
2023-10-17 |
Janssen Biotech, Inc. |
Materials and methods for improved single chain variable fragments
|
|
JP2022553306A
(ja)
|
2019-10-21 |
2022-12-22 |
ノバルティス アーゲー |
Ｔｉｍ－３阻害剤およびその使用
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
EP4055046A1
(en)
|
2019-11-06 |
2022-09-14 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
|
KR20220114560A
(ko)
|
2019-11-18 |
2022-08-17 |
얀센 바이오테크 인코포레이티드 |
항-cd79 키메라 항원 수용체, car-t 세포 및 이의 용도
|
|
PH12022551291A1
(en)
|
2019-11-26 |
2023-11-20 |
Novartis Ag |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
CN110964119A
(zh)
*
|
2019-12-05 |
2020-04-07 |
沣潮医药科技（上海）有限公司 |
抗疟二聚体免疫粘附素、药物组合物和用途
|
|
WO2021116337A1
(en)
|
2019-12-11 |
2021-06-17 |
Cilag Gmbh International |
Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof
|
|
AU2020403913B2
(en)
|
2019-12-18 |
2024-10-10 |
F. Hoffmann-La Roche Ag |
Bispecific anti-CCL2 antibodies
|
|
CN114828965B
(zh)
|
2019-12-18 |
2025-09-05 |
豪夫迈·罗氏有限公司 |
与hla-a2/mage-a4结合的抗体
|
|
CN115175937A
(zh)
|
2019-12-20 |
2022-10-11 |
诺华股份有限公司 |
用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合
|
|
CN114930170A
(zh)
|
2020-01-02 |
2022-08-19 |
豪夫迈·罗氏有限公司 |
用于测定脑中的治疗性抗体量的方法
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
PE20230113A1
(es)
|
2020-01-16 |
2023-01-27 |
Genmab As |
Formulaciones de anticuerpos anti-cd38 y usos de las mismas
|
|
US20210222244A1
(en)
|
2020-01-17 |
2021-07-22 |
Becton, Dickinson And Company |
Methods and compositions for single cell secretomics
|
|
KR20220128389A
(ko)
|
2020-01-17 |
2022-09-20 |
노파르티스 아게 |
골수이형성 증후군 또는 만성 골수단핵구성 백혈병을 치료하는데 사용하기 위한 tim-3 억제제 및 저메틸화제를 포함하는 조합물
|
|
IL295129A
(en)
|
2020-01-30 |
2022-09-01 |
Umoja Biopharma Inc |
Bispecific transduction enhancer
|
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
|
JOP20220184A1
(ar)
|
2020-02-12 |
2023-01-30 |
Janssen Biotech Inc |
علاج مصابي السرطان ممن لديهم طفرات تخطي c-Met إكسون14
|
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
AU2021225949A1
(en)
|
2020-02-27 |
2022-09-15 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
UY40280A
(es)
|
2020-03-13 |
2023-07-31 |
Janssen Biotech Inc |
Dominios de unión a antígeno que se unen a la proteina cd33 de la superficie de células mieloides
|
|
CN115298221A
(zh)
|
2020-03-18 |
2022-11-04 |
健玛保 |
结合b7h4的抗体
|
|
KR20230020394A
(ko)
|
2020-04-15 |
2023-02-10 |
보이저 테라퓨틱스, 인크. |
Tau 결합 화합물
|
|
US20230192795A1
(en)
|
2020-04-15 |
2023-06-22 |
Hoffmann-La Roche Inc. |
Immunoconjugates
|
|
US20230138852A1
(en)
|
2020-04-16 |
2023-05-04 |
Janssen Biotech, Inc. |
Systems, materials, and methods for reversed-phase high performance liquid chromatography (rp-hplc) identification of multi-specific molecules
|
|
KR20230028242A
(ko)
|
2020-04-24 |
2023-02-28 |
마렝고 테라퓨틱스, 인크. |
T 세포 관련 암 세포에 결합하는 다중기능성 분자 및 그것의 용도
|
|
CA3180173A1
(en)
|
2020-04-30 |
2021-11-04 |
Bristol-Myers Squibb Company |
Methods of treating cytokine-related adverse events
|
|
CN115916166A
(zh)
|
2020-05-08 |
2023-04-04 |
健玛保 |
针对cd3和cd20的双特异性抗体
|
|
CA3182697A1
(en)
|
2020-05-11 |
2021-11-18 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma
|
|
BR112022022614A2
(pt)
|
2020-05-11 |
2023-02-07 |
Hoffmann La Roche |
Métodos para estimular uma resposta imune, melhorar uma imunoterapia, tratar uma doença, reduzir crescimento tumoral, produzir um imunoconjugado e produzir uma composição, método de vacinação, imunoconjugados, composição, usos e kits
|
|
CN116249714A
(zh)
|
2020-05-27 |
2023-06-09 |
詹森生物科技公司 |
包含cd3抗原结合结构域的蛋白质及其用途
|
|
GB202008860D0
(en)
|
2020-06-11 |
2020-07-29 |
Univ Oxford Innovation Ltd |
BTLA antibodies
|
|
EP4168446A1
(en)
|
2020-06-19 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Antibodies binding to cd3 and folr1
|
|
MX2022016069A
(es)
|
2020-06-19 |
2023-02-02 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y cd19.
|
|
AR122658A1
(es)
|
2020-06-19 |
2022-09-28 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3
|
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
|
IL296225A
(en)
|
2020-06-19 |
2022-11-01 |
Hoffmann La Roche |
Immune activating fc domain binding molecules
|
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
US12295997B2
(en)
|
2020-07-06 |
2025-05-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
MX2023000547A
(es)
|
2020-07-16 |
2023-02-13 |
Novartis Ag |
Anticuerpos anti-betacelulina, fragmentos de los mismos, y moleculas de union multiespecificas.
|
|
US20230293680A1
(en)
|
2020-07-23 |
2023-09-21 |
Genmab B.V. |
A composition of anti-dr5 antibodies and an immunomodulatory imide drug for use in treating multiple myeloma
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
JP2023536818A
(ja)
|
2020-07-29 |
2023-08-30 |
ヤンセン バイオテツク，インコーポレーテツド |
Ｈｌａ－ｇ抗原結合ドメインを含むタンパク質及びそれらの使用
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
JP2023537470A
(ja)
|
2020-08-03 |
2023-09-01 |
ヤンセン バイオテツク，インコーポレーテツド |
ウイルス治療における多方向バイオ輸送のための材料及び方法
|
|
AU2021322046A1
(en)
|
2020-08-06 |
2023-02-02 |
BioNTech SE |
Binding agents for coronavirus S protein
|
|
MX2023001708A
(es)
|
2020-08-10 |
2023-05-04 |
Janssen Biotech Inc |
Materiales y métodos para producir linfocitos específicos de virus diseñados mediante bioingeniería.
|
|
CN116249718A
(zh)
|
2020-08-26 |
2023-06-09 |
马伦戈治疗公司 |
结合至钙网蛋白的多功能性分子及其用途
|
|
WO2022047046A1
(en)
|
2020-08-26 |
2022-03-03 |
Marengo Therapeutics, Inc. |
Methods of detecting trbc1 or trbc2
|
|
CN116917316A
(zh)
|
2020-08-26 |
2023-10-20 |
马伦戈治疗公司 |
与NKp30结合的抗体分子及其用途
|
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
CN116472060A
(zh)
|
2020-09-02 |
2023-07-21 |
健玛保 |
抗体疗法
|
|
CN116406293A
(zh)
|
2020-09-10 |
2023-07-07 |
健玛保 |
用于治疗滤泡性淋巴瘤的联合疗法中的针对cd3和cd20的双特异性抗体
|
|
CN116782933A
(zh)
|
2020-09-10 |
2023-09-19 |
健玛保 |
用于治疗弥漫性大b细胞淋巴瘤的联合疗法中的针对cd3和cd20的双特异性抗体
|
|
CA3192251A1
(en)
|
2020-09-10 |
2022-03-17 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
JP2023542092A
(ja)
|
2020-09-10 |
2023-10-05 |
ジェンマブ エー／エス |
びまん性大細胞型ｂ細胞リンパ腫を治療するための併用療法におけるｃｄ３及びｃｄ２０に対する二重特異性抗体
|
|
BR112023004351A2
(pt)
|
2020-09-10 |
2023-04-04 |
Genmab As |
Método para tratar linfoma folicular em um sujeito humano
|
|
CA3190349A1
(en)
|
2020-09-10 |
2022-03-17 |
Brian Elliott |
Bispecific antibodies against cd3 and cd20 for treating chronic lymphocytic leukemia
|
|
US12448449B2
(en)
|
2020-09-11 |
2025-10-21 |
Janssen Biotech, Inc. |
Immune targeting molecules and uses thereof
|
|
US11965024B2
(en)
|
2020-09-11 |
2024-04-23 |
Janssen Biotech, Inc. |
Methods and compositions for modulating beta chain mediated immunity
|
|
IL301366A
(en)
|
2020-09-24 |
2023-05-01 |
Hoffmann La Roche |
Mammalian cell lines with gene knockout
|
|
IL301513A
(en)
|
2020-10-02 |
2023-05-01 |
Genmab As |
Antibodies capable of binding to ror2 and bispecific antibodies binding to ror2 and cd3
|
|
US11926667B2
(en)
|
2020-10-13 |
2024-03-12 |
Janssen Biotech, Inc. |
Bioengineered T cell mediated immunity, materials and other methods for modulating cluster of differentiation IV and/or VIII
|
|
JP2023548034A
(ja)
|
2020-10-22 |
2023-11-15 |
ヤンセン バイオテツク，インコーポレーテツド |
デルタ様リガンド３（ｄｌｌ３）抗原結合ドメインを含むタンパク質及びその使用
|
|
WO2022093888A1
(en)
|
2020-10-28 |
2022-05-05 |
Janssen Biotech, Inc. |
Compositions and methods for modulating delta gamma chain mediated immunity
|
|
WO2022098638A2
(en)
|
2020-11-04 |
2022-05-12 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
|
JP7716473B2
(ja)
|
2020-11-04 |
2025-07-31 |
ジェネンテック， インコーポレイテッド |
抗ｃｄ２０／抗ｃｄ３二重特異性抗体の皮下投薬
|
|
US20240010748A1
(en)
|
2020-11-10 |
2024-01-11 |
Shanghai Qilu Pharmaceutical Research And Development Centre Ltd. |
Bispecific antibody for claudin 18a2 and cd3 and application of bispecific antibody
|
|
CN116635062A
(zh)
|
2020-11-13 |
2023-08-22 |
诺华股份有限公司 |
使用表达嵌合抗原受体（car）的细胞的组合疗法
|
|
JP7326584B2
(ja)
|
2020-12-17 |
2023-08-15 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
抗ｈｌａ－ｇ抗体及びその使用
|
|
WO2022129313A1
(en)
|
2020-12-18 |
2022-06-23 |
F. Hoffmann-La Roche Ag |
Precursor proteins and kit for targeted therapy
|
|
JP2024501662A
(ja)
|
2020-12-22 |
2024-01-15 |
エフ． ホフマン－ラ ロシュ アーゲー |
Ｘｂｐ１を標的とするオリゴヌクレオチド
|
|
JP2024503826A
(ja)
|
2021-01-06 |
2024-01-29 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｐｄ１－ｌａｇ３二重特異性抗体及びｃｄ２０ ｔ細胞二重特異性抗体を用いる併用療法
|
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
|
PE20240761A1
(es)
|
2021-01-28 |
2024-04-17 |
Janssen Biotech Inc |
Proteinas de union a psma y usos de estas
|
|
JP2024505049A
(ja)
|
2021-01-29 |
2024-02-02 |
ノバルティス アーゲー |
抗ｃｄ７３及び抗ｅｎｔｐｄ２抗体のための投与方式並びにその使用
|
|
IL305144A
(en)
|
2021-02-16 |
2023-10-01 |
Janssen Pharmaceutica Nv |
Trispecific antibodies targeting BCMA, GPRC5D and CD3
|
|
BR112023016360A2
(pt)
|
2021-02-16 |
2024-01-23 |
Janssen Biotech Inc |
Materiais e métodos para determinação aprimorada de ligante alvo
|
|
EP4295154A1
(en)
|
2021-02-18 |
2023-12-27 |
F. Hoffmann-La Roche AG |
Method for resolving complex, multistep antibody interactions
|
|
BR112023018278A2
(pt)
|
2021-03-09 |
2023-10-31 |
Janssen Biotech Inc |
Tratamento de cânceres sem mutações de ativação de egfr
|
|
KR20230156921A
(ko)
|
2021-03-12 |
2023-11-15 |
젠맵 에이/에스 |
비-활성화 항체 변이체
|
|
US12084501B2
(en)
|
2021-03-24 |
2024-09-10 |
Janssen Biotech, Inc. |
Proteins comprising CD3 antigen binding domains and uses thereof
|
|
TW202304986A
(zh)
|
2021-03-24 |
2023-02-01 |
美商健生生物科技公司 |
靶向cd22及cd79b的抗體
|
|
BR112023019484A2
(pt)
|
2021-03-24 |
2023-12-05 |
Janssen Biotech Inc |
Anticorpo triespecífico que tem como alvo cd79b, cd20 e cd3
|
|
WO2022206872A1
(zh)
|
2021-03-31 |
2022-10-06 |
江苏恒瑞医药股份有限公司 |
截短的taci多肽及其融合蛋白和用途
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4320147A4
(en)
|
2021-04-08 |
2025-06-18 |
Marengo Therapeutics, Inc. |
TCR-BINDING MULTIFUNCTIONAL MOLECULES AND USES THEREOF
|
|
WO2022228706A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
|
AU2021443318A1
(en)
|
2021-04-30 |
2023-09-07 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
|
MX2023012351A
(es)
|
2021-05-07 |
2023-10-31 |
Genmab As |
Composiciones farmaceuticas que comprenden anticuerpos biespecificos que se unen al inhibidor de la activacion de celulas t que contiene un dominio v-set 1 (b7h4) y cumulo de diferenciacion 3 (cd3).
|
|
KR20240006586A
(ko)
|
2021-05-12 |
2024-01-15 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
Rankl 및 ngf에 특이적으로 결합하는 항원 결합 분자, 및 이의 의학적 용도
|
|
CA3218578A1
(en)
|
2021-05-14 |
2022-11-17 |
Carol Elaine O'hear |
Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin
|
|
US20240392020A1
(en)
|
2021-05-14 |
2024-11-28 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
TW202309094A
(zh)
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
用於識別癌症患者以進行組合治療之方法
|
|
AU2022295067A1
(en)
|
2021-06-18 |
2023-12-21 |
F. Hoffmann-La Roche Ag |
Bispecific anti-ccl2 antibodies
|
|
IL309319A
(en)
|
2021-06-21 |
2024-02-01 |
Genmab As |
Combined dosage regimen CD137 and PD-L1 binding agents
|
|
TW202309078A
(zh)
|
2021-07-02 |
2023-03-01 |
美商建南德克公司 |
治療癌症之方法及組成物
|
|
JP2024527581A
(ja)
|
2021-07-09 |
2024-07-25 |
ヤンセン バイオテツク，インコーポレーテツド |
抗ｉｌ１２／ｉｌ２３抗体組成物を生産するための製造方法
|
|
US20230042465A1
(en)
|
2021-07-09 |
2023-02-09 |
Janssen Biotech, Inc. |
Manufacturing Methods for Producing Anti-TNF Antibody Compositions
|
|
EP4367136A1
(en)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
|
JP2024528573A
(ja)
|
2021-07-14 |
2024-07-30 |
江蘇恒瑞医薬股▲ふん▼有限公司 |
Ｈｇｆｒとｅｇｆｒに特異的に結合する抗原結合分子及びその医薬使用
|
|
WO2023001884A1
(en)
|
2021-07-22 |
2023-01-26 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
|
WO2023006809A1
(en)
|
2021-07-27 |
2023-02-02 |
Morphosys Ag |
Combinations of antigen binding molecules
|
|
CN117715936A
(zh)
|
2021-07-28 |
2024-03-15 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的方法和组合物
|
|
US20250270314A1
(en)
|
2021-08-02 |
2025-08-28 |
Tavotek Biotech (Suzhou) Ltd |
Anti-cdh17 monoclonal and bispecific antibodies and uses thereof
|
|
US20250277051A1
(en)
|
2021-08-02 |
2025-09-04 |
Hangzhou Unogen Biotech, Ltd |
Anti-cd38 antibodies, anti-cd3 antibodies, and bispecific antibodies, and uses thereof
|
|
EP4399227A1
(en)
|
2021-09-06 |
2024-07-17 |
Genmab A/S |
Antibodies capable of binding to cd27, variants thereof and uses thereof
|
|
TW202328193A
(zh)
|
2021-09-13 |
2023-07-16 |
美商健生生物科技公司 |
用於治療癌症的CD33 x Vδ2多特異性抗體
|
|
EP4405396A2
(en)
|
2021-09-20 |
2024-07-31 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
EP4406968A4
(en)
|
2021-09-23 |
2025-03-12 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
ANTI-KLB ANTIBODIES AND USES
|
|
US20250019455A1
(en)
|
2021-09-24 |
2025-01-16 |
Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
|
CA3233261A1
(en)
|
2021-09-30 |
2023-04-06 |
Langyong MAO |
Anti-il23 antibody fusion protein and uses thereof
|
|
IL311805A
(en)
|
2021-10-08 |
2024-05-01 |
Genmab As |
Antibodies that bind to CD30 and CD3
|
|
PE20241627A1
(es)
|
2021-10-14 |
2024-08-07 |
Hoffmann La Roche |
Nuevos inmunoconjugados de interleucina-7
|
|
JP2024537096A
(ja)
|
2021-10-14 |
2024-10-10 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療のための代替的なＰＤ１－ＩＬ７ｖイムノコンジュゲート
|
|
AU2022369278A1
(en)
|
2021-10-18 |
2024-05-02 |
Tavotek Biotherapeutics (Hong Kong) Limited |
ANTI-EGFR ANTIBODIES, ANTI-cMET ANTIBODIES, ANTI-VEGF ANTIBODIES, MULTISPECIFIC ANTIBODIES, AND USES THEREOF
|
|
IL312464A
(en)
|
2021-11-01 |
2024-06-01 |
Janssen Biotech Inc |
Compositions and methods for the modulation of beta chain-mediated immunity
|
|
AU2022380722A1
(en)
|
2021-11-03 |
2024-06-20 |
Janssen Biotech, Inc. |
Methods of treating cancers and enhancing efficacy of bcmaxcd3 bispecific antibodies
|
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
EP4436669A1
(en)
|
2021-11-22 |
2024-10-02 |
Janssen Biotech, Inc. |
Compositions comprising enhanced multispecific binding agents for an immune response
|
|
EP4437344A1
(en)
|
2021-11-25 |
2024-10-02 |
F. Hoffmann-La Roche AG |
Quantification of low amounts of antibody sideproducts
|
|
US20230183360A1
(en)
|
2021-12-09 |
2023-06-15 |
Janssen Biotech, Inc. |
Use of Amivantamab to Treat Colorectal Cancer
|
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
|
WO2023122723A1
(en)
|
2021-12-23 |
2023-06-29 |
The Broad Institute, Inc. |
Panels and methods for diagnosing and treating lung cancer
|
|
AU2023208426A1
(en)
|
2022-01-24 |
2024-07-25 |
Novimmune Sa |
Composition and methods for the selective activation of cytokine signaling pathways
|
|
JP2025503177A
(ja)
|
2022-01-28 |
2025-01-30 |
ジェンマブ エー／エス |
びまん性大細胞型ｂ細胞リンパ腫を治療するための併用療法におけるｃｄ３及びｃｄ２０に対する二重特異性抗体
|
|
WO2023144290A1
(en)
|
2022-01-28 |
2023-08-03 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
JP2025505650A
(ja)
|
2022-02-07 |
2025-02-28 |
ビステラ， インコーポレイテッド |
抗イディオタイプ抗体分子及びその使用
|
|
TW202342057A
(zh)
|
2022-02-07 |
2023-11-01 |
美商健生生物科技公司 |
用於減少用ｅｇｆｒ／ｍｅｔ雙特異性抗體治療之患者的輸注相關反應之方法
|
|
WO2023147784A1
(zh)
|
2022-02-07 |
2023-08-10 |
江苏恒瑞医药股份有限公司 |
特异性结合psma和cd3的抗原结合分子及其医药用途
|
|
MX2024009715A
(es)
|
2022-02-11 |
2024-08-19 |
Jiangsu Hengrui Pharmaceuticals Co Ltd |
Inmunoconjugado y su uso del mismo.
|
|
IL314916A
(en)
|
2022-03-07 |
2024-10-01 |
Novimmune Sa |
Bispecific CD28 antibodies for targeted T cell activation
|
|
JP2025509702A
(ja)
|
2022-03-14 |
2025-04-11 |
ラムキャップ バイオ ガンマ エージー |
ＧＰＣ３陽性悪性細胞を標的殺傷するための二重特異性ＧＰＣ３ｘＣＤ２８抗体およびＧＰＣ３ｘＣＤ３抗体ならびにそれらの組み合わせ
|
|
US20250215083A1
(en)
|
2022-03-14 |
2025-07-03 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule specifically binding to gprc5d and cd3 and medical use thereof
|
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
|
KR20240164782A
(ko)
|
2022-03-23 |
2024-11-20 |
에프. 호프만-라 로슈 아게 |
항-cd20/항-cd3 이중특이적 항체와 화학요법의 병용 치료
|
|
PE20250559A1
(es)
|
2022-03-29 |
2025-02-24 |
Ngm Biopharmaceuticals Inc |
Agentes de union a ilt3 y cd3 y metodos de uso de estos
|
|
CA3255366A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions based on bispecific anti-CD20/anti-CD3 antibodies and methods of use
|
|
WO2023198839A2
(en)
|
2022-04-13 |
2023-10-19 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
|
WO2023202967A1
(en)
|
2022-04-19 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
|
AR129136A1
(es)
|
2022-04-26 |
2024-07-17 |
Novartis Ag |
Anticuerpos multiespecíficos que se dirigen a il-13 e il-18
|
|
CA3253038A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
LIAISON AGENTS CAPABLE OF BINDING TO CD27 IN POLYTHERAPY
|
|
JP2025516633A
(ja)
|
2022-05-12 |
2025-05-30 |
ジェンマブ エー／エス |
併用療法においてｃｄ２７に結合する能力を有する結合剤
|
|
EP4522757A2
(en)
|
2022-05-13 |
2025-03-19 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
EP4532526A1
(en)
|
2022-06-03 |
2025-04-09 |
F. Hoffmann-La Roche AG |
Improved production cells
|
|
WO2023246885A1
(zh)
|
2022-06-23 |
2023-12-28 |
江苏恒瑞医药股份有限公司 |
特异性结合dll3和cd3的抗原结合分子及其医药用途
|
|
JP2025522814A
(ja)
|
2022-06-30 |
2025-07-17 |
ヤンセン バイオテツク，インコーポレーテツド |
胃癌又は食道癌を治療するための抗ｅｇｆｒ／抗ｍｅｔ抗体の使用
|
|
TW202435912A
(zh)
|
2022-08-03 |
2024-09-16 |
美商航海家醫療公司 |
用於穿過血腦屏障之組合物及方法
|
|
JP2025525885A
(ja)
|
2022-08-05 |
2025-08-07 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 |
Ｇｕｃｙ２ｃとｃｄ３に特異的に結合する抗原結合分子及びその医薬的使用
|
|
JP2025535203A
(ja)
|
2022-09-15 |
2025-10-23 |
ボイジャー セラピューティクス インコーポレイテッド |
タウ結合化合物
|
|
TW202430211A
(zh)
|
2022-10-10 |
2024-08-01 |
瑞士商赫孚孟拉羅股份公司 |
Ｇｐｒｃ５ｄ ｔｃｂ及ｉｍｉｄ之組合療法
|
|
TW202423970A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Ｇｐｒｃ５ｄ ｔｃｂ及ｃｄ３８抗體之組合療法
|
|
TW202423969A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Ｇｐｒｃ５ｄ ｔｃｂ及蛋白酶體抑制劑之組合療法
|
|
CN120019277A
(zh)
|
2022-10-12 |
2025-05-16 |
豪夫迈·罗氏有限公司 |
用于对细胞进行分类的方法
|
|
IL320152A
(en)
|
2022-10-21 |
2025-06-01 |
Novimmune Sa |
Bispecific antibodies against PD-L1 and CD28 for immune checkpoint-dependent T cell activation
|
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
|
EP4612177A1
(en)
|
2022-10-31 |
2025-09-10 |
Genmab A/S |
Cd38 antibodies and uses thereof
|
|
TW202432596A
(zh)
|
2022-11-01 |
2024-08-16 |
大陸商上海齊魯製藥研究中心有限公司 |
針對磷脂醯肌醇蛋白聚醣3的雙特異性抗體及其應用
|
|
KR20250097946A
(ko)
|
2022-11-02 |
2025-06-30 |
얀센 바이오테크 인코포레이티드 |
암을 치료하는 방법
|
|
EP4612179A1
(en)
|
2022-11-02 |
2025-09-10 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20 for treating richter's syndrome
|
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
|
JP2025537782A
(ja)
|
2022-11-15 |
2025-11-20 |
エフ． ホフマン－ラ ロシュ アーゲー |
活性化可能なエフェクタードメインを有する組換え結合タンパク質
|
|
WO2024104933A1
(en)
|
2022-11-15 |
2024-05-23 |
F. Hoffmann-La Roche Ag |
Antigen binding molecules
|
|
CN120077072A
(zh)
|
2022-11-29 |
2025-05-30 |
江苏恒瑞医药股份有限公司 |
Cldn18.2/4-1bb结合蛋白及其医药用途
|
|
EP4651885A1
(en)
|
2023-01-20 |
2025-11-26 |
F. Hoffmann-La Roche AG |
Recombinant fc domain - il2 variant polypeptides and combination therapy with membrane-anchored antigen binding polypeptides
|
|
WO2024156672A1
(en)
|
2023-01-25 |
2024-08-02 |
F. Hoffmann-La Roche Ag |
Antibodies binding to csf1r and cd3
|
|
WO2024163009A1
(en)
|
2023-01-31 |
2024-08-08 |
Genentech, Inc. |
Methods and compositions for treating urothelial bladder cancer
|
|
TW202436339A
(zh)
|
2023-01-31 |
2024-09-16 |
瑞士商赫孚孟拉羅股份公司 |
治療選自非小細胞肺癌或三陰性乳癌的癌症之用途
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
CN121127496A
(zh)
|
2023-02-09 |
2025-12-12 |
杨森生物技术公司 |
抗Vβ17/抗CD123双特异性抗体
|
|
AU2024226611A1
(en)
|
2023-02-21 |
2025-08-28 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Il-36r binding protein and medicinal use thereof
|
|
WO2024184287A1
(en)
|
2023-03-06 |
2024-09-12 |
F. Hoffmann-La Roche Ag |
Combination therapy of an anti-egfrviii/anti-cd3 antibody and an tumor-targeted 4-1bb agonist
|
|
KR20250158056A
(ko)
|
2023-03-13 |
2025-11-05 |
얀센 바이오테크 인코포레이티드 |
이중특이성 항-egfr/c-met 항체 및 항-pd-1 항체를 사용한 병용 요법
|
|
WO2024188965A1
(en)
|
2023-03-13 |
2024-09-19 |
F. Hoffmann-La Roche Ag |
Combination therapy employing a pd1-lag3 bispecific antibody and an hla-g t cell bispecific antibody
|
|
CN120917044A
(zh)
|
2023-04-03 |
2025-11-07 |
豪夫迈·罗氏有限公司 |
激动性拆分型抗体
|
|
WO2024208777A1
(en)
|
2023-04-03 |
2024-10-10 |
F. Hoffmann-La Roche Ag |
All-in-one agonistic antibodies
|
|
TW202506178A
(zh)
|
2023-04-05 |
2025-02-16 |
丹麥商珍美寶股份有限公司 |
包含與ｃｄ３０和ｃｄ３結合之抗體之醫藥組成物
|
|
WO2024213040A1
(zh)
|
2023-04-11 |
2024-10-17 |
浙江博锐生物制药有限公司 |
抗ror1抗体及其药物偶联物
|
|
KR20250169618A
(ko)
|
2023-04-13 |
2025-12-03 |
젠맵 에이/에스 |
Cd3 및 cd20에 대한 이중특이적 항체를 사용하여 림프종을 치료하는 방법
|
|
AR132623A1
(es)
|
2023-05-08 |
2025-07-16 |
Hoffmann La Roche |
PROTEÍNAS DE FUSIÓN DE INTERFERÓN a DIRIGIDAS Y MÉTODOS DE USO
|
|
AU2024271605A1
(en)
|
2023-05-12 |
2025-11-13 |
BioNTech SE |
Antibodies capable of binding to ox40, variants thereof and uses thereof
|
|
AU2024273454A1
(en)
|
2023-05-16 |
2025-11-27 |
F. Hoffmann-La Roche Ag |
Pd-1-regulated il-2 immunocytokine and uses thereof
|
|
CA3228195A1
(en)
|
2023-05-23 |
2025-06-30 |
Janssen Biotech, Inc. |
Methods for treatment of non-small cell lung cancer (nsclc)
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
JP2025530208A
(ja)
|
2023-06-30 |
2025-09-11 |
ジェンマブ エー／エス |
線維芽細胞活性化タンパク質アルファおよびデスレセプター４に結合する抗体
|
|
WO2025021838A1
(en)
|
2023-07-26 |
2025-01-30 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
WO2025027511A1
(en)
|
2023-07-30 |
2025-02-06 |
Janssen Biotech, Inc. |
Molecules that bind to mutant calreticulin and uses thereof
|
|
US20250136688A1
(en)
|
2023-08-07 |
2025-05-01 |
Janssen Biotech, Inc. |
Stabilized cd3 antigen binding agents and methods of use thereof
|
|
WO2025032508A1
(en)
|
2023-08-07 |
2025-02-13 |
Janssen Biotech, Inc. |
Enpp3 and cd3 binding agents and methods of use thereof
|
|
US20250066510A1
(en)
|
2023-08-07 |
2025-02-27 |
Janssen Biotech, Inc. |
Gucy2c antibodies and uses thereof
|
|
WO2025032071A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025032069A1
(en)
|
2023-08-09 |
2025-02-13 |
F. Hoffmann-La Roche Ag |
Mono and multispecific anti-trem2 antibodies, methods and uses thereof
|
|
WO2025036892A1
(en)
|
2023-08-14 |
2025-02-20 |
Morphosys Ag |
Cycat halfbody molecules comprising sterically occluding moieties
|
|
WO2025042742A1
(en)
|
2023-08-18 |
2025-02-27 |
Bristol-Myers Squibb Company |
Compositions comprising antibodies that bind bcma and cd3 and methods of treatment
|
|
WO2025052273A1
(en)
|
2023-09-05 |
2025-03-13 |
Janssen Biotech, Inc. |
Methods of treating non-small cell lung cancer
|
|
US20250075000A1
(en)
|
2023-09-06 |
2025-03-06 |
Novimmune Sa |
Combination therapy with a cea x cd28 bispecific antibody and blocking anti-pd-1 antibodies for enhanced in vivo anti-tumor activity
|
|
WO2025059162A1
(en)
|
2023-09-11 |
2025-03-20 |
Dana-Farber Cancer Institute, Inc. |
Car-engager containing il-2 variants to enhance the functionality of car t cells
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025079020A1
(en)
|
2023-10-12 |
2025-04-17 |
Janssen Biotech, Inc. |
First line treatment in egfr exon 20 insertion-mutated advanced non-small cell lung cancer
|
|
WO2025082777A1
(en)
|
2023-10-17 |
2025-04-24 |
Morphosys Ag |
Dual-targeting of muc16 and mesothelin co-expressing tumor cells by functional complementation of cycat® halfbody molecules
|
|
WO2025085610A1
(en)
|
2023-10-18 |
2025-04-24 |
Janssen Biotech, Inc. |
Combination treatment of prostate cancers with two bispecific antibodies
|
|
TW202535406A
(zh)
|
2023-10-30 |
2025-09-16 |
美商壯生和壯生企業創新公司 |
用於治療肺癌之a2a受體拮抗劑
|
|
WO2025114541A1
(en)
|
2023-11-30 |
2025-06-05 |
Genmab A/S |
Antibodies capable of binding to ox40 in combination therapy
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
TW202535947A
(zh)
|
2023-12-08 |
2025-09-16 |
美商健生生物科技公司 |
ＣＤ３３抗體、ＣＤ３３／Ｖδ２多特異性抗體及其用途
|
|
WO2025125386A1
(en)
|
2023-12-14 |
2025-06-19 |
F. Hoffmann-La Roche Ag |
Antibodies that bind to folr1 and methods of use
|
|
WO2025151018A1
(ko)
*
|
2024-01-12 |
2025-07-17 |
주식회사 노벨티노빌리티 |
C-kit 및 vegf에 특이적으로 결합하는 이중특이적 항체 및 이의 용도
|
|
WO2025153988A1
(en)
|
2024-01-16 |
2025-07-24 |
Janssen Biotech, Inc. |
Use of amivantamab to treat colorectal cancer
|
|
WO2025158277A1
(en)
|
2024-01-22 |
2025-07-31 |
Janssen Biotech, Inc. |
Use of amivantamab to treat head and neck cancer
|
|
WO2025181189A1
(en)
|
2024-03-01 |
2025-09-04 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
|
WO2025191459A1
(en)
|
2024-03-11 |
2025-09-18 |
Janssen Biotech, Inc. |
Use of bispecific anti-egfr/c-met antibodies to treat solid tumors
|
|
WO2025202147A1
(en)
|
2024-03-27 |
2025-10-02 |
F. Hoffmann-La Roche Ag |
Interleukin-7 immunoconjugates
|
|
WO2025221728A2
(en)
|
2024-04-15 |
2025-10-23 |
Janssen Biotech, Inc. |
Ltbr binding molecules and uses thereof
|
|
WO2025219504A1
(en)
|
2024-04-19 |
2025-10-23 |
F. Hoffmann-La Roche Ag |
Treatment of ophthalmologic diseases
|
|
WO2025226541A2
(en)
|
2024-04-26 |
2025-10-30 |
Janssen Biotech, Inc. |
Klk2xcd3 antibody and an anti-cancer agent for treating prostate cancer
|
|
WO2025231408A2
(en)
|
2024-05-03 |
2025-11-06 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma with car-t cells and bispecific antibodies
|
|
WO2025233825A1
(en)
|
2024-05-06 |
2025-11-13 |
Janssen Pharmaceutica Nv |
Enrichment of cells expressing a bird linker
|
|
WO2025237931A1
(en)
|
2024-05-15 |
2025-11-20 |
F. Hoffmann-La Roche Ag |
Recombinant binding proteins with conditionally activatable t cell and nk cell recruiting effector domains
|
|
US20250361317A1
(en)
|
2024-05-24 |
2025-11-27 |
Janssen Biotech, Inc. |
Bispecific antibody targeting emr2 (cd312) and the t-cell receptor trbv19
|
