|
US2512572A
(en)
|
|
1950-06-20 |
|
Substituted pteridines and method |
|
US2563707A
(en)
|
1947-12-12 |
1951-08-07 |
American Cyanamid Co |
Process for preparing pteridines
|
|
GB768821A
(en)
|
1954-05-17 |
1957-02-20 |
Gruenenthal Chemie |
Novel products of the amino-piperidine-2, 6-dione series
|
|
US2759300A
(en)
|
1954-08-11 |
1956-08-21 |
Pest Control Ltd |
Method and means for introducing a predetermined amount of a poisonous material beneath the surface of the soil
|
|
US3053865A
(en)
|
1958-03-19 |
1962-09-11 |
Merck & Co Inc |
Novel 16-alkyl and 16-alkylene steroids and processes
|
|
US2960527A
(en)
|
1958-08-20 |
1960-11-15 |
Akad Wissenschaften Ddr |
Process for the preparation of dichloro phosphoric esters
|
|
US3097137A
(en)
|
1960-05-19 |
1963-07-09 |
Canadian Patents Dev |
Vincaleukoblastine
|
|
US3104246A
(en)
|
1961-08-18 |
1963-09-17 |
Roussel Uclaf |
Process of preparation of beta-methasone
|
|
FR1533151A
(fr)
|
1962-05-18 |
1968-07-19 |
Rhone Poulenc Sa |
Nouvel antibiotique et sa préparation
|
|
NL6613143A
(enExample)
|
1965-09-21 |
1967-03-22 |
|
|
|
YU33730B
(en)
|
1967-04-18 |
1978-02-28 |
Farmaceutici Italia |
Process for preparing a novel antibiotic substance and salts thereof
|
|
US3480613A
(en)
|
1967-07-03 |
1969-11-25 |
Merck & Co Inc |
2-c or 3-c-alkylribofuranosyl - 1-substituted compounds and the nucleosides thereof
|
|
CH514578A
(de)
|
1968-02-27 |
1971-10-31 |
Sandoz Ag |
Verfahren zur Herstellung von Glucosiden
|
|
JPS4716483Y1
(enExample)
|
1969-03-01 |
1972-06-09 |
|
|
|
US3798209A
(en)
|
1971-06-01 |
1974-03-19 |
Icn Pharmaceuticals |
1,2,4-triazole nucleosides
|
|
USRE29835E
(en)
|
1971-06-01 |
1978-11-14 |
Icn Pharmaceuticals |
1,2,4-Triazole nucleosides
|
|
US3849397A
(en)
|
1971-08-04 |
1974-11-19 |
Int Chem & Nuclear Corp |
3',5'-cyclic monophosphate nucleosides
|
|
US3994974A
(en)
|
1972-02-05 |
1976-11-30 |
Yamanouchi Pharmaceutical Co., Ltd. |
α-Aminomethylbenzyl alcohol derivatives
|
|
US3852267A
(en)
|
1972-08-04 |
1974-12-03 |
Icn Pharmaceuticals |
Phosphoramidates of 3{40 ,5{40 -cyclic purine nucleotides
|
|
ZA737247B
(en)
|
1972-09-29 |
1975-04-30 |
Ayerst Mckenna & Harrison |
Rapamycin and process of preparation
|
|
BE799805A
(fr)
|
1973-05-23 |
1973-11-21 |
Toyo Jozo Kk |
Nouvel agent immunosuppresseur et sa preparation
|
|
JPS535678B2
(enExample)
|
1973-05-30 |
1978-03-01 |
|
|
|
US3991045A
(en)
|
1973-05-30 |
1976-11-09 |
Asahi Kasei Kogyo Kabushiki Kaisha |
N4 -acylarabinonucleosides
|
|
US3888843A
(en)
|
1973-06-12 |
1975-06-10 |
Toyo Jozo Kk |
4-carbamoyl-1-' -d-ribofuranosylimidazolium-5-olate
|
|
SU508076A1
(ru)
|
1973-07-05 |
1976-10-05 |
Институт По Изысканию Новых Антибиотиков Амн Ссср |
Способ получени карминомицина 1
|
|
GB1457632A
(en)
|
1974-03-22 |
1976-12-08 |
Farmaceutici Italia |
Adriamycins
|
|
US3923785A
(en)
|
1974-04-22 |
1975-12-02 |
Parke Davis & Co |
(R)-3-(2-deoxy-{62 -D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo{8 4,5-d{9 {8 1,3{9 diazepin-8-ol
|
|
GB1467383A
(en)
|
1974-06-12 |
1977-03-16 |
Farmaceutici Italia |
Daunomycin analogues
|
|
GB1523865A
(en)
|
1974-09-02 |
1978-09-06 |
Wellcome Found |
Purine compunds and salts thereof
|
|
US4199574A
(en)
|
1974-09-02 |
1980-04-22 |
Burroughs Wellcome Co. |
Methods and compositions for treating viral infections and guanine acyclic nucleosides
|
|
GB1509875A
(en)
|
1976-06-14 |
1978-05-04 |
Farmaceutici Italia |
Optically active anthracyclinones and anthracycline glycosides
|
|
SE445996B
(sv)
|
1977-08-15 |
1986-08-04 |
American Cyanamid Co |
Nya atrakinonderivat
|
|
US4197249A
(en)
|
1977-08-15 |
1980-04-08 |
American Cyanamid Company |
1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
|
|
US4203898A
(en)
|
1977-08-29 |
1980-05-20 |
Eli Lilly And Company |
Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
|
|
US4210745A
(en)
|
1978-01-04 |
1980-07-01 |
The United States Of America As Represented By The Department Of Health, Education And Welfare |
Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine
|
|
US4303785A
(en)
|
1978-08-05 |
1981-12-01 |
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai |
Antitumor anthracycline antibiotics
|
|
US4307100A
(en)
|
1978-08-24 |
1981-12-22 |
Agence Nationale De Valorisation De La Recherche (Anvar) |
Nor bis-indole compounds usable as medicaments
|
|
DK160616C
(da)
|
1979-02-03 |
1991-09-02 |
Zaidan Hojin Biseibutsu |
Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf
|
|
NZ200204A
(en)
|
1981-04-03 |
1985-05-31 |
Lilly Co Eli |
Benzothiophene derivatives and process for preparation
|
|
US4418068A
(en)
|
1981-04-03 |
1983-11-29 |
Eli Lilly And Company |
Antiestrogenic and antiandrugenic benzothiophenes
|
|
US4355032B2
(en)
|
1981-05-21 |
1990-10-30 |
|
9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
|
|
JPS58219196A
(ja)
|
1982-06-15 |
1983-12-20 |
Nippon Kayaku Co Ltd |
４′−デメチル−エピポドフイロトキシン−β−Ｄ−エチリデングルコシドの製造法
|
|
JPS5976099A
(ja)
|
1982-10-22 |
1984-04-28 |
Sumitomo Chem Co Ltd |
アミノナフタセン誘導体とその製造方法
|
|
IT1155446B
(it)
|
1982-12-23 |
1987-01-28 |
Erba Farmitalia |
Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
|
|
US4526988A
(en)
|
1983-03-10 |
1985-07-02 |
Eli Lilly And Company |
Difluoro antivirals and intermediate therefor
|
|
JPS6019790A
(ja)
|
1983-07-14 |
1985-01-31 |
Yakult Honsha Co Ltd |
新規なカンプトテシン誘導体
|
|
EP0141927B1
(en)
|
1983-08-18 |
1991-10-30 |
Beecham Group Plc |
Antiviral guanine derivatives
|
|
JPS6051189A
(ja)
|
1983-08-30 |
1985-03-22 |
Sankyo Co Ltd |
チアゾリジン誘導体およびその製造法
|
|
US4894366A
(en)
|
1984-12-03 |
1990-01-16 |
Fujisawa Pharmaceutical Company, Ltd. |
Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
|
|
US4760137A
(en)
|
1984-08-06 |
1988-07-26 |
Brigham Young University |
Method for the production of 2'-deoxyadenosine compounds
|
|
CA1269659A
(en)
|
1984-08-06 |
1990-05-29 |
Brigham Young University |
Method for the production of 2'-deoxyadenosine compounds
|
|
US5736155A
(en)
|
1984-08-08 |
1998-04-07 |
The Liposome Company, Inc. |
Encapsulation of antineoplastic agents in liposomes
|
|
US5077056A
(en)
|
1984-08-08 |
1991-12-31 |
The Liposome Company, Inc. |
Encapsulation of antineoplastic agents in liposomes
|
|
NL8403224A
(nl)
|
1984-10-24 |
1986-05-16 |
Oce Andeno Bv |
Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen.
|
|
DK173350B1
(da)
|
1985-02-26 |
2000-08-07 |
Sankyo Co |
Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
|
|
US5223263A
(en)
|
1988-07-07 |
1993-06-29 |
Vical, Inc. |
Liponucleotide-containing liposomes
|
|
US4724232A
(en)
|
1985-03-16 |
1988-02-09 |
Burroughs Wellcome Co. |
Treatment of human viral infections
|
|
CS263951B1
(en)
|
1985-04-25 |
1989-05-12 |
Antonin Holy |
9-(phosponylmethoxyalkyl)adenines and method of their preparation
|
|
NZ216172A
(en)
|
1985-05-15 |
1989-08-29 |
Wellcome Found |
Nucleosides and pharmaceutical compositions
|
|
US5246937A
(en)
|
1985-09-18 |
1993-09-21 |
Beecham Group P.L.C. |
Purine derivatives
|
|
US4751221A
(en)
|
1985-10-18 |
1988-06-14 |
Sloan-Kettering Institute For Cancer Research |
2-fluoro-arabinofuranosyl purine nucleosides
|
|
US4797285A
(en)
|
1985-12-06 |
1989-01-10 |
Yissum Research And Development Company Of The Hebrew University Of Jerusalem |
Lipsome/anthraquinone drug composition and method
|
|
NZ219974A
(en)
|
1986-04-22 |
1989-08-29 |
Goedecke Ag |
N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases
|
|
FR2601675B1
(fr)
|
1986-07-17 |
1988-09-23 |
Rhone Poulenc Sante |
Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
US4753935A
(en)
|
1987-01-30 |
1988-06-28 |
Syntex (U.S.A.) Inc. |
Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions
|
|
US5154930A
(en)
|
1987-03-05 |
1992-10-13 |
The Liposome Company, Inc. |
Pharmacological agent-lipid solution preparation
|
|
EP0303697B1
(en)
|
1987-03-09 |
1997-10-01 |
Kyowa Hakko Kogyo Co., Ltd. |
Derivatives of physiologically active substance k-252
|
|
GB8719367D0
(en)
|
1987-08-15 |
1987-09-23 |
Wellcome Found |
Therapeutic compounds
|
|
EP0380558A4
(en)
|
1987-09-22 |
1991-07-31 |
The Regents Of The University Of California |
Liposomal nucleoside analogues for treating aids
|
|
US5004758A
(en)
|
1987-12-01 |
1991-04-02 |
Smithkline Beecham Corporation |
Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
|
|
US4880784A
(en)
|
1987-12-21 |
1989-11-14 |
Brigham Young University |
Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
|
|
US5130421A
(en)
|
1988-03-24 |
1992-07-14 |
Bristol-Myers Company |
Production of 2',3'-dideoxy-2',3'-didehydronucleosides
|
|
GB8815265D0
(en)
|
1988-06-27 |
1988-08-03 |
Wellcome Found |
Therapeutic nucleosides
|
|
IL91664A
(en)
|
1988-09-28 |
1993-05-13 |
Yissum Res Dev Co |
Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release
|
|
US6132763A
(en)
|
1988-10-20 |
2000-10-17 |
Polymasc Pharmaceuticals Plc |
Liposomes
|
|
US5705363A
(en)
|
1989-03-02 |
1998-01-06 |
The Women's Research Institute |
Recombinant production of human interferon τ polypeptides and nucleic acids
|
|
US5549910A
(en)
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5077057A
(en)
|
1989-04-05 |
1991-12-31 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5277914A
(en)
|
1989-03-31 |
1994-01-11 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5194654A
(en)
|
1989-11-22 |
1993-03-16 |
Vical, Inc. |
Lipid derivatives of phosphonoacids for liposomal incorporation and method of use
|
|
US5411947A
(en)
|
1989-06-28 |
1995-05-02 |
Vestar, Inc. |
Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5225212A
(en)
|
1989-10-20 |
1993-07-06 |
Liposome Technology, Inc. |
Microreservoir liposome composition and method
|
|
US5463092A
(en)
|
1989-11-22 |
1995-10-31 |
Vestar, Inc. |
Lipid derivatives of phosphonacids for liposomal incorporation and method of use
|
|
GB8927913D0
(en)
|
1989-12-11 |
1990-02-14 |
Hoffmann La Roche |
Amino acid derivatives
|
|
US5026687A
(en)
|
1990-01-03 |
1991-06-25 |
The United States Of America As Represented By The Department Of Health And Human Services |
Treatment of human retroviral infections with 2',3'-dideoxyinosine alone and in combination with other antiviral compounds
|
|
US5041246A
(en)
|
1990-03-26 |
1991-08-20 |
The Babcock & Wilcox Company |
Two stage variable annulus spray attemperator method and apparatus
|
|
ATE194844T1
(de)
|
1990-04-06 |
2000-08-15 |
Genelabs Tech Inc |
Hepatitis c-virus-epitope
|
|
US5091188A
(en)
|
1990-04-26 |
1992-02-25 |
Haynes Duncan H |
Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
|
|
GB9009861D0
(en)
|
1990-05-02 |
1990-06-27 |
Glaxo Group Ltd |
Chemical compounds
|
|
WO1991016920A1
(en)
|
1990-05-07 |
1991-11-14 |
Vical, Inc. |
Lipid prodrugs of salicylate and nonsteroidal anti-inflammatory drugs
|
|
WO1991017748A1
(de)
|
1990-05-18 |
1991-11-28 |
Hoechst Aktiengesellschaft |
Isoxazol-4-carbonsäureamide und hydroxyalkyliden-cyanessigsäureamide, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
JPH05507279A
(ja)
|
1990-05-29 |
1993-10-21 |
ネクススター・ファーマシューティカルズ・インコーポレイテッド |
グリセロールジ―およびトリホスフェート誘導体の合成
|
|
EP0533833B1
(en)
|
1990-06-13 |
1995-12-20 |
GLAZIER, Arnold |
Phosphorous produgs
|
|
US6060080A
(en)
|
1990-07-16 |
2000-05-09 |
Daiichi Pharmaceutical Co., Ltd. |
Liposomal products
|
|
JP2599492B2
(ja)
|
1990-08-21 |
1997-04-09 |
第一製薬株式会社 |
リポソーム製剤の製造法
|
|
US5372808A
(en)
|
1990-10-17 |
1994-12-13 |
Amgen Inc. |
Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect
|
|
US5206244A
(en)
|
1990-10-18 |
1993-04-27 |
E. R. Squibb & Sons, Inc. |
Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines
|
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
|
US5149794A
(en)
|
1990-11-01 |
1992-09-22 |
State Of Oregon |
Covalent lipid-drug conjugates for drug targeting
|
|
US5256641A
(en)
|
1990-11-01 |
1993-10-26 |
State Of Oregon |
Covalent polar lipid-peptide conjugates for immunological targeting
|
|
US5543389A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non Profit Organization |
Covalent polar lipid-peptide conjugates for use in salves
|
|
US5179104A
(en)
|
1990-12-05 |
1993-01-12 |
University Of Georgia Research Foundation, Inc. |
Process for the preparation of enantiomerically pure β-D-(-)-dioxolane-nucleosides
|
|
US5925643A
(en)
|
1990-12-05 |
1999-07-20 |
Emory University |
Enantiomerically pure β-D-dioxolane-nucleosides
|
|
JP3008226B2
(ja)
|
1991-01-16 |
2000-02-14 |
第一製薬株式会社 |
六環性化合物
|
|
US5145684A
(en)
|
1991-01-25 |
1992-09-08 |
Sterling Drug Inc. |
Surface modified drug nanoparticles
|
|
IL100965A
(en)
|
1991-02-22 |
1999-12-31 |
Univ Emory |
2-Hydroxymethyl-5-(5-fluorocytosin-l-yl)-1,3-oxathiolane its resolution and pharmaceutical compositions containing it
|
|
IE920754A1
(en)
|
1991-03-08 |
1992-09-09 |
Univ Vermont |
6,9 BIS(SUBSTITUTED-AMINO) BENZO[g]-ISOQUINOLINE-5,10-DIONES
|
|
US5595732A
(en)
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
|
US5157027A
(en)
|
1991-05-13 |
1992-10-20 |
E. R. Squibb & Sons, Inc. |
Bisphosphonate squalene synthetase inhibitors and method
|
|
AU668873B2
(en)
|
1991-07-12 |
1996-05-23 |
Chimerix, Inc. |
Antiviral liponucleosides: treatment of hepatitis B
|
|
NZ243567A
(en)
|
1991-07-22 |
1995-04-27 |
Bristol Myers Squibb Co |
Pharmaceutical oral formulation of a dideoxy purine nucleoside comprising the nucleoside together with a water-insoluble antacid buffering composition
|
|
US5554728A
(en)
|
1991-07-23 |
1996-09-10 |
Nexstar Pharmaceuticals, Inc. |
Lipid conjugates of therapeutic peptides and protease inhibitors
|
|
GB9116601D0
(en)
|
1991-08-01 |
1991-09-18 |
Iaf Biochem Int |
1,3-oxathiolane nucleoside analogues
|
|
TW224053B
(enExample)
|
1991-09-13 |
1994-05-21 |
Paul B Chretien |
|
|
DE4200821A1
(de)
|
1992-01-15 |
1993-07-22 |
Bayer Ag |
Geschmacksmaskierte pharmazeutische mittel
|
|
US5676942A
(en)
|
1992-02-10 |
1997-10-14 |
Interferon Sciences, Inc. |
Composition containing human alpha interferon species proteins and method for use thereof
|
|
US5405598A
(en)
|
1992-02-24 |
1995-04-11 |
Schinazi; Raymond F. |
Sensitizing agents for use in boron neutron capture therapy
|
|
US5610054A
(en)
|
1992-05-14 |
1997-03-11 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecule targeted against Hepatitis C virus
|
|
US5256798A
(en)
|
1992-06-22 |
1993-10-26 |
Eli Lilly And Company |
Process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates
|
|
US5426183A
(en)
|
1992-06-22 |
1995-06-20 |
Eli Lilly And Company |
Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
|
|
HU214030B
(en)
|
1992-06-22 |
1997-12-29 |
Lilly Co Eli |
Process for preparing alpha-anomer enriched 1-halogen-2-deoxy-2,2-difluoro-d-ribofuranosyl derivatives
|
|
US5719147A
(en)
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
CA2105112C
(en)
|
1992-09-01 |
2005-08-02 |
Thomas C. Britton |
A process for anomerizing nucleosides
|
|
GB9221220D0
(en)
|
1992-10-09 |
1992-11-25 |
Sandoz Ag |
Organic componds
|
|
GB9226729D0
(en)
|
1992-12-22 |
1993-02-17 |
Wellcome Found |
Therapeutic combination
|
|
US5484926A
(en)
|
1993-10-07 |
1996-01-16 |
Agouron Pharmaceuticals, Inc. |
HIV protease inhibitors
|
|
CN1078478C
(zh)
|
1993-02-24 |
2002-01-30 |
王瑞駪 |
活性抗病毒聚合物的组成及应用方法
|
|
US6180134B1
(en)
|
1993-03-23 |
2001-01-30 |
Sequus Pharmaceuticals, Inc. |
Enhanced ciruclation effector composition and method
|
|
AU701574B2
(en)
|
1993-05-12 |
1999-02-04 |
Karl Y. Hostetler |
Acyclovir derivatives for topical use
|
|
US5846964A
(en)
|
1993-07-19 |
1998-12-08 |
Tokyo Tanabe Company Limited |
Hepatitis C virus proliferation inhibitor
|
|
FR2707988B1
(fr)
|
1993-07-21 |
1995-10-13 |
Pf Medicament |
Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
|
|
US6156501A
(en)
|
1993-10-26 |
2000-12-05 |
Affymetrix, Inc. |
Arrays of modified nucleic acid probes and methods of use
|
|
US7375198B2
(en)
|
1993-10-26 |
2008-05-20 |
Affymetrix, Inc. |
Modified nucleic acid probes
|
|
HUT75533A
(en)
|
1993-11-10 |
1997-05-28 |
Schering Corp |
Improved interferon polymer conjugates
|
|
US5951974A
(en)
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
|
AU6550394A
(en)
|
1994-03-11 |
1995-09-25 |
Isis Pharmaceuticals, Inc. |
Novel pyrimidine nucleosides
|
|
DE4415539C2
(de)
|
1994-05-03 |
1996-08-01 |
Osama Dr Dr Med Omer |
Pflanzen mit virustatischer und antiviraler Wirkung
|
|
IL129871A
(en)
|
1994-05-06 |
2003-11-23 |
Pharmacia & Upjohn Inc |
Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections
|
|
JPH10501809A
(ja)
|
1994-06-22 |
1998-02-17 |
ネクスター ファーマスーティカルズ，インコーポレイテッド |
分子内求核置換による公知および新規２′−ヌクレオシドの新規製造方法
|
|
DE4432623A1
(de)
|
1994-09-14 |
1996-03-21 |
Huels Chemische Werke Ag |
Verfahren zur Bleichung von wäßrigen Tensidlösungen
|
|
US5738846A
(en)
|
1994-11-10 |
1998-04-14 |
Enzon, Inc. |
Interferon polymer conjugates and process for preparing the same
|
|
US5696277A
(en)
|
1994-11-15 |
1997-12-09 |
Karl Y. Hostetler |
Antiviral prodrugs
|
|
US6391859B1
(en)
|
1995-01-27 |
2002-05-21 |
Emory University |
[5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
|
|
US5703058A
(en)
|
1995-01-27 |
1997-12-30 |
Emory University |
Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
|
|
GB9505025D0
(en)
|
1995-03-13 |
1995-05-03 |
Medical Res Council |
Chemical compounds
|
|
GB9618952D0
(en)
|
1996-09-11 |
1996-10-23 |
Sandoz Ltd |
Process
|
|
US6504029B1
(en)
|
1995-04-10 |
2003-01-07 |
Daiichi Pharmaceutical Co., Ltd. |
Condensed-hexacyclic compounds and a process therefor
|
|
DE19514523A1
(de)
|
1995-04-12 |
1996-10-17 |
Schering Ag |
Neue Cytosin- und Cytidinderivate
|
|
ATE318896T1
(de)
|
1995-09-27 |
2006-03-15 |
Univ Emory |
Rekombinante rna-replikase von hepatitis-c-virus
|
|
US5908621A
(en)
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
|
US5767097A
(en)
|
1996-01-23 |
1998-06-16 |
Icn Pharmaceuticals, Inc. |
Specific modulation of Th1/Th2 cytokine expression by ribavirin in activated T-lymphocytes
|
|
GB9602028D0
(en)
|
1996-02-01 |
1996-04-03 |
Amersham Int Plc |
Nucleoside analogues
|
|
US5980884A
(en)
|
1996-02-05 |
1999-11-09 |
Amgen, Inc. |
Methods for retreatment of patients afflicted with Hepatitis C using consensus interferon
|
|
AU2064297A
(en)
|
1996-02-29 |
1997-09-16 |
Immusol, Inc |
Hepatitis c virus ribozymes
|
|
US5830905A
(en)
|
1996-03-29 |
1998-11-03 |
Viropharma Incorporated |
Compounds, compositions and methods for treatment of hepatitis C
|
|
US5633388A
(en)
|
1996-03-29 |
1997-05-27 |
Viropharma Incorporated |
Compounds, compositions and methods for treatment of hepatitis C
|
|
US5849733A
(en)
|
1996-05-10 |
1998-12-15 |
Bristol-Myers Squibb Co. |
2-thio or 2-oxo flavopiridol analogs
|
|
US5990276A
(en)
|
1996-05-10 |
1999-11-23 |
Schering Corporation |
Synthetic inhibitors of hepatitis C virus NS3 protease
|
|
GB9609932D0
(en)
|
1996-05-13 |
1996-07-17 |
Hoffmann La Roche |
Use of IL-12 and IFN alpha for the treatment of infectious diseases
|
|
US5891874A
(en)
|
1996-06-05 |
1999-04-06 |
Eli Lilly And Company |
Anti-viral compound
|
|
US5837257A
(en)
|
1996-07-09 |
1998-11-17 |
Sage R&D |
Use of plant extracts for treatment of HIV, HCV and HBV infections
|
|
US6214375B1
(en)
|
1996-07-16 |
2001-04-10 |
Generex Pharmaceuticals, Inc. |
Phospholipid formulations
|
|
US5635517B1
(en)
|
1996-07-24 |
1999-06-29 |
Celgene Corp |
Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
|
|
AU4090697A
(en)
|
1996-09-03 |
1998-03-26 |
Bristol-Myers Squibb Company |
Improved process for preparing the antiviral agent {1s-(1alpha, 3alpha, 4beta)}-2-amino-1,9-dihydro-9-{4-hydroxy-3-(hydroxymethyl)-2 -methylenecyclopentyl}-6h-purin-6-one
|
|
US5908934A
(en)
|
1996-09-26 |
1999-06-01 |
Bristol-Myers Squibb Company |
Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs
|
|
US6174905B1
(en)
|
1996-09-30 |
2001-01-16 |
Mitsui Chemicals, Inc. |
Cell differentiation inducer
|
|
US5922757A
(en)
|
1996-09-30 |
1999-07-13 |
The Regents Of The University Of California |
Treatment and prevention of hepatic disorders
|
|
US6224903B1
(en)
|
1996-10-11 |
2001-05-01 |
Sequus Pharmaceuticals, Inc. |
Polymer-lipid conjugate for fusion of target membranes
|
|
TW520297B
(en)
|
1996-10-11 |
2003-02-11 |
Sequus Pharm Inc |
Fusogenic liposome composition and method
|
|
US6509320B1
(en)
|
1996-10-16 |
2003-01-21 |
Icn Pharmaceuticals, Inc. |
Purine L-nucleosides, analogs and uses thereof
|
|
US6455690B1
(en)
|
1996-10-16 |
2002-09-24 |
Robert Tam |
L-8-oxo-7-propyl-7,8-dihydro-(9H)-guanosine
|
|
CN1268140A
(zh)
|
1996-10-16 |
2000-09-27 |
Icn药品公司 |
单环l－核苷、类似物及其应用
|
|
HUP0001186A3
(en)
|
1996-10-16 |
2002-04-29 |
Icn Pharmaceuticals Inc Costa |
Purine l-nucleosides,analogs and pharmaceutical compositions thereof
|
|
CZ298749B6
(cs)
|
1996-10-18 |
2008-01-16 |
Vertex Pharmaceuticals Incorporated |
Inhibitory serinových proteáz a farmaceutické prostředky s jejich obsahem
|
|
GB9623908D0
(en)
|
1996-11-18 |
1997-01-08 |
Hoffmann La Roche |
Amino acid derivatives
|
|
IL119833A
(en)
|
1996-12-15 |
2001-01-11 |
Lavie David |
Hypericum perforatum extracts for the preparation of pharmaceutical compositions for the treatment of hepatitis
|
|
US5827533A
(en)
|
1997-02-06 |
1998-10-27 |
Duke University |
Liposomes containing active agents aggregated with lipid surfactants
|
|
US20020127371A1
(en)
|
2001-03-06 |
2002-09-12 |
Weder Donald E. |
Decorative elements provided with a circular or crimped configuration at point of sale or point of use
|
|
US6004933A
(en)
|
1997-04-25 |
1999-12-21 |
Cortech Inc. |
Cysteine protease inhibitors
|
|
CN1107068C
(zh)
|
1997-05-29 |
2003-04-30 |
诺瓦提斯公司 |
2－氨基－7－(1－取代的－2－羟乙基)－3,5－二氢－吡咯并[3,2－d]嘧啶－4－酮
|
|
WO1999001416A2
(en)
|
1997-06-30 |
1999-01-14 |
Merz + Co. Gmbh & Co. |
1-amino-alkylcyclohexane nmda receptor antagonists
|
|
WO1999007734A2
(en)
|
1997-08-11 |
1999-02-18 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor peptide analogues
|
|
PT903148E
(pt)
|
1997-09-21 |
2002-02-28 |
Schering Corp |
Terapia de combinacao para a erradicacao de rna de hcv detectavel em doentes tendo infeccao cronica pelo virus da hepatite c
|
|
US6703374B1
(en)
|
1997-10-30 |
2004-03-09 |
The United States Of America As Represented By The Department Of Health And Human Services |
Nucleosides for imaging and treatment applications
|
|
US5981709A
(en)
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
|
IL137164A0
(en)
|
1998-01-23 |
2001-07-24 |
Newbiotics Inc |
Enzyme catalyzed therapeutic agents
|
|
AU2787199A
(en)
|
1998-02-25 |
1999-09-15 |
Emory University |
2'-fluoronucleosides
|
|
US6787305B1
(en)
|
1998-03-13 |
2004-09-07 |
Invitrogen Corporation |
Compositions and methods for enhanced synthesis of nucleic acid molecules
|
|
CA2326535A1
(en)
|
1998-03-27 |
1999-10-07 |
Regents Of The University Of Minnesota |
Nucleosides with antiviral and anticancer activity
|
|
GB9806815D0
(en)
|
1998-03-30 |
1998-05-27 |
Hoffmann La Roche |
Amino acid derivatives
|
|
KR100694345B1
(ko)
|
1998-05-15 |
2007-03-12 |
쉐링 코포레이션 |
리바비린 및 인터페론 알파를 포함하는, 만성 ｃ형 간염에 걸린 항-바이러스 치료에 대한 나이브 환자의 치료용 약제학적 조성물
|
|
US20010014352A1
(en)
|
1998-05-27 |
2001-08-16 |
Udit Batra |
Compressed tablet formulation
|
|
US6274725B1
(en)
|
1998-06-02 |
2001-08-14 |
Isis Pharmaceuticals, Inc. |
Activators for oligonucleotide synthesis
|
|
TR200003635T2
(tr)
|
1998-06-08 |
2001-04-20 |
F.Hoffmann-La Roche Ag |
Peg-IFN-ALFA ve ribavirinin kronik hepatit C tedavisinde kullanılması.
|
|
US6726925B1
(en)
|
1998-06-18 |
2004-04-27 |
Duke University |
Temperature-sensitive liposomal formulation
|
|
US6200598B1
(en)
|
1998-06-18 |
2001-03-13 |
Duke University |
Temperature-sensitive liposomal formulation
|
|
US6320078B1
(en)
|
1998-07-24 |
2001-11-20 |
Mitsui Chemicals, Inc. |
Method of producing benzamide derivatives
|
|
ATE298317T1
(de)
|
1998-07-27 |
2005-07-15 |
Angeletti P Ist Richerche Bio |
Diketosäure-derivate als hemmstoffe von polymerasen
|
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
|
ATE313550T1
(de)
|
1998-08-10 |
2006-01-15 |
Idenix Cayman Ltd |
Beta-l-2'-deoxynukleoside für die behandlung von hepatitis b virus
|
|
JP4533537B2
(ja)
|
1998-10-16 |
2010-09-01 |
メルシャン株式会社 |
塩酸ドキソルビシンの結晶化
|
|
FR2784892B1
(fr)
|
1998-10-23 |
2001-04-06 |
Smith & Nephew Kinetec Sa |
Attelle de mobilisation passive repliable pour membre inferieur
|
|
GB9826555D0
(en)
|
1998-12-03 |
1999-01-27 |
Univ Nottingham |
Microemulsion compositions
|
|
US6635278B1
(en)
|
1998-12-15 |
2003-10-21 |
Gilead Sciences, Inc. |
Pharmaceutical formulations
|
|
EP1140143A2
(en)
|
1998-12-18 |
2001-10-10 |
Schering Corporation |
Ribavirin-pegylated interferon alfa induction hcv combination therapy
|
|
US6294192B1
(en)
|
1999-02-26 |
2001-09-25 |
Lipocine, Inc. |
Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
|
|
US6267985B1
(en)
|
1999-06-30 |
2001-07-31 |
Lipocine Inc. |
Clear oil-containing pharmaceutical compositions
|
|
US6248363B1
(en)
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
US6383471B1
(en)
|
1999-04-06 |
2002-05-07 |
Lipocine, Inc. |
Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
|
|
US6395300B1
(en)
|
1999-05-27 |
2002-05-28 |
Acusphere, Inc. |
Porous drug matrices and methods of manufacture thereof
|
|
US7919119B2
(en)
|
1999-05-27 |
2011-04-05 |
Acusphere, Inc. |
Porous drug matrices and methods of manufacture thereof
|
|
CN1079473C
(zh)
|
1999-05-31 |
2002-02-20 |
李岭群 |
预制梁连接筋
|
|
WO2001005433A2
(en)
|
1999-07-14 |
2001-01-25 |
Board Of Regents, The University Of Texas System |
Delivery and retention of activity agents to lymph nodes
|
|
AU6388900A
(en)
|
1999-07-30 |
2001-02-19 |
Abbott Gmbh & Co. Kg |
2-pyrazolin-5-ones
|
|
US6566365B1
(en)
|
1999-11-04 |
2003-05-20 |
Biochem Pharma Inc. |
Method for the treatment of Flaviviridea viral infection using nucleoside analogues
|
|
KR100789162B1
(ko)
|
1999-11-12 |
2007-12-28 |
파마셋 인코포레이티드 |
2'-데옥시-ｌ-뉴클레오사이드의 합성
|
|
US20060034937A1
(en)
|
1999-11-23 |
2006-02-16 |
Mahesh Patel |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
US6495677B1
(en)
|
2000-02-15 |
2002-12-17 |
Kanda S. Ramasamy |
Nucleoside compounds
|
|
JP2003523978A
(ja)
|
2000-02-18 |
2003-08-12 |
シャイアー・バイオケム・インコーポレイテッド |
ヌクレオシドアナログを用いるｆｌａｖｉｖｉｒｕｓ感染の処置もしくは予防するための方法
|
|
ES2319732T3
(es)
|
2000-04-13 |
2009-05-12 |
Pharmasset, Inc. |
Derivados de nucleosido 3'- o 2'-hidroximetilo sustituido para el tratamiento de infecciones virales.
|
|
WO2001081359A1
(en)
|
2000-04-20 |
2001-11-01 |
Schering Corporation |
Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection
|
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
US6596700B2
(en)
|
2000-05-26 |
2003-07-22 |
Idenix Pharmaceuticals Inc. |
Methods of treating hepatitis delta virus infection with β-L-2'-deoxy-nucleosides
|
|
US6787526B1
(en)
|
2000-05-26 |
2004-09-07 |
Idenix Pharmaceuticals, Inc. |
Methods of treating hepatitis delta virus infection with β-L-2′-deoxy-nucleosides
|
|
JP5230052B2
(ja)
|
2000-05-26 |
2013-07-10 |
イデニクス（ケイマン）リミテツド |
フラビウイルスおよびペスチウイルス治療のための方法および組成物
|
|
FR2810322B1
(fr)
|
2000-06-14 |
2006-11-10 |
Pasteur Institut |
PRODUCTION COMBINATOIRE D'ANALOGUES DE NUCLEOTIDES ET NUCLEOTIDES (XiTP)
|
|
MY141594A
(en)
|
2000-06-15 |
2010-05-14 |
Novirio Pharmaceuticals Ltd |
3'-PRODRUGS OF 2'-DEOXY-ß-L-NUCLEOSIDES
|
|
US6815542B2
(en)
|
2000-06-16 |
2004-11-09 |
Ribapharm, Inc. |
Nucleoside compounds and uses thereof
|
|
US6680068B2
(en)
|
2000-07-06 |
2004-01-20 |
The General Hospital Corporation |
Drug delivery formulations and targeting
|
|
UA72612C2
(en)
|
2000-07-06 |
2005-03-15 |
|
Pyrido[2.3-d]pyrimidine and pyrimido[4.5-d]pyrimidine nucleoside analogues, prodrugs and method for inhibiting growth of neoplastic cells
|
|
AR034127A1
(es)
|
2000-07-21 |
2004-02-04 |
Schering Corp |
Imidazolidinonas como inhibidores de ns3-serina proteasa del virus de hepatitis c, composicion farmaceutica, un metodo para su preparacion, y el uso de las mismas para la manufactura de un medicamento
|
|
AR029851A1
(es)
|
2000-07-21 |
2003-07-16 |
Dendreon Corp |
Nuevos peptidos como inhibidores de ns3-serina proteasa del virus de hepatitis c
|
|
US20020068702A1
(en)
|
2000-07-21 |
2002-06-06 |
Marguerita Lim-Wilby |
Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
RU2003105221A
(ru)
|
2000-07-21 |
2004-09-20 |
Шеринг Корпорейшн (US) |
Новые пептиды, как ингибиторы ns3-серинпротеазы вируса гепатита с
|
|
OA12393A
(en)
|
2000-07-21 |
2006-04-18 |
Gilead Sciences Inc |
Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same.
|
|
US7018985B1
(en)
|
2000-08-21 |
2006-03-28 |
Inspire Pharmaceuticals, Inc. |
Composition and method for inhibiting platelet aggregation
|
|
AR039558A1
(es)
|
2000-08-21 |
2005-02-23 |
Inspire Pharmaceuticals Inc |
Composiciones y metodo para el tratamiento de glaucoma o hipertension ocular
|
|
US6897201B2
(en)
|
2000-08-21 |
2005-05-24 |
Inspire Pharmaceuticals, Inc. |
Compositions and methods for the treatment of glaucoma or ocular hypertension
|
|
US20030008841A1
(en)
|
2000-08-30 |
2003-01-09 |
Rene Devos |
Anti-HCV nucleoside derivatives
|
|
ATE491459T1
(de)
|
2000-10-18 |
2011-01-15 |
Pharmasset Inc |
Modifizierte nukleoside zur behandlung von virusinfektionen und abnormaler zellulärer proliferation
|
|
AU2002213343A1
(en)
|
2000-10-18 |
2002-04-29 |
Schering Corporation |
Ribavirin-pegylated interferon alfa HCV combination therapy
|
|
US6555677B2
(en)
|
2000-10-31 |
2003-04-29 |
Merck & Co., Inc. |
Phase transfer catalyzed glycosidation of an indolocarbazole
|
|
CA2429359A1
(en)
|
2000-11-20 |
2002-08-08 |
Bristol-Myers Squibb Company |
Hepatitis c tripeptide inhibitors
|
|
DE20019797U1
(de)
|
2000-11-21 |
2001-04-05 |
MALA Verschlußsysteme GmbH, 36448 Schweina |
Verschlußkappe
|
|
CN1301994C
(zh)
|
2000-12-12 |
2007-02-28 |
先灵公司 |
作为c型肝炎病毒ns3－丝氨酸蛋白酶抑制剂的二芳基肽
|
|
US6727366B2
(en)
|
2000-12-13 |
2004-04-27 |
Bristol-Myers Squibb Pharma Company |
Imidazolidinones and their related derivatives as hepatitis C virus NS3 protease inhibitors
|
|
AU2002230763A1
(en)
|
2000-12-13 |
2008-01-03 |
Bristol-Myers Squibb Pharma Company |
Inhibitors of hepatitis c virus ns3 protease
|
|
US6750396B2
(en)
|
2000-12-15 |
2004-06-15 |
Di/Dt, Inc. |
I-channel surface-mount connector
|
|
WO2002048165A2
(en)
|
2000-12-15 |
2002-06-20 |
Pharmasset Ltd. |
Antiviral agents for treatment of flaviviridae infections
|
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
DZ3487A1
(fr)
|
2001-01-22 |
2002-07-25 |
Merck Sharp & Dohme |
Derives de nucleoside comme inhibiteurs de l'arn polymerase virale d'arn-dependant
|
|
MY129350A
(en)
|
2001-04-25 |
2007-03-30 |
Bristol Myers Squibb Co |
Aripiprazole oral solution
|
|
GB0112617D0
(en)
|
2001-05-23 |
2001-07-18 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
|
EP1404694A1
(en)
|
2001-06-21 |
2004-04-07 |
Glaxo Group Limited |
Nucleoside compounds in hcv
|
|
JP4455056B2
(ja)
|
2001-07-11 |
2010-04-21 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
架橋二環式セリンプロテアーゼ阻害剤
|
|
EP2335700A1
(en)
|
2001-07-25 |
2011-06-22 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis C virus polymerase inhibitors with a heterobicylic structure
|
|
WO2003011877A2
(en)
|
2001-08-02 |
2003-02-13 |
Ilex Oncology Inc. |
Process for preparing purine nucleosides
|
|
US6962991B2
(en)
|
2001-09-12 |
2005-11-08 |
Epoch Biosciences, Inc. |
Process for the synthesis of pyrazolopyrimidines
|
|
US7227019B2
(en)
|
2001-09-13 |
2007-06-05 |
Bristol-Myers Squibb Company |
Process for the preparation of rebeccamycin and analogs thereof
|
|
WO2003024461A1
(en)
|
2001-09-20 |
2003-03-27 |
Schering Corporation |
Hcv combination therapy
|
|
WO2003026589A2
(en)
|
2001-09-28 |
2003-04-03 |
Idenix (Cayman) Limited |
Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
|
|
ES2289161T3
(es)
|
2001-11-02 |
2008-02-01 |
Glaxo Group Limited |
Derivados de 4-(heteroaril de 6 miembros)-acil pirrolidina como inhibidores de hcv.
|
|
AU2002359518A1
(en)
|
2001-11-27 |
2003-06-10 |
Bristol-Myers Squibb Company |
Efavirenz tablet formulation having unique biopharmaceutical characteristics
|
|
GB0129945D0
(en)
|
2001-12-13 |
2002-02-06 |
Mrc Technology Ltd |
Chemical compounds
|
|
KR100978904B1
(ko)
|
2001-12-14 |
2010-08-31 |
파마셋 인코포레이티드 |
바이러스 감염 치료용 ｎ4-아실사이토신 뉴클레오사이드
|
|
AU2002353165A1
(en)
|
2001-12-17 |
2003-06-30 |
Ribapharm Inc. |
Deazapurine nucleoside libraries and compounds
|
|
CA2470521A1
(en)
|
2001-12-21 |
2003-07-10 |
Micrologix Biotech Inc. |
Anti-viral 7-deaza l-nucleosides
|
|
WO2003062256A1
(en)
|
2002-01-17 |
2003-07-31 |
Ribapharm Inc. |
2'-beta-modified-6-substituted adenosine analogs and their use as antiviral agents
|
|
US7070801B2
(en)
|
2002-01-30 |
2006-07-04 |
National Institute Of Advanced Industrial Science And Technology |
Sugar-modified liposome and products comprising the liposome
|
|
US6642204B2
(en)
|
2002-02-01 |
2003-11-04 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
|
CA2370396A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
|
US20050118596A1
(en)
|
2002-02-08 |
2005-06-02 |
Asselbergs Fredericus Alphonsus M. |
Method for screening for compounds having hdac inhibitory activity
|
|
US7323453B2
(en)
|
2002-02-13 |
2008-01-29 |
Merck & Co., Inc. |
Methods of inhibiting orthopoxvirus replication with nucleoside compounds
|
|
US20040023901A1
(en)
|
2002-02-28 |
2004-02-05 |
Cook Phillip D. |
Nucleoside 5'-monophosphate mimics and their prodrugs
|
|
EP1485395A4
(en)
|
2002-02-28 |
2011-04-13 |
Biota Scient Management |
NUCLEOTIDE MIMETICS AND PRODRUGS THEREOF
|
|
WO2003090691A2
(en)
|
2002-04-26 |
2003-11-06 |
Gilead Sciences, Inc. |
Method and compositions for identifying anti-hiv therapeutic compounds
|
|
AU2003241621A1
(en)
|
2002-05-24 |
2003-12-12 |
Isis Pharmaceuticals, Inc. |
Oligonucleotides having modified nucleoside units
|
|
AU2003240488A1
(en)
|
2002-06-04 |
2003-12-19 |
Neogenesis Pharmaceuticals, Inc. |
Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents
|
|
JP4902958B2
(ja)
|
2002-06-07 |
2012-03-21 |
ユニバーシテール・メディッシュ・セントラム・ユトレヒト |
ｃＡＭＰによって直接活性化される交換タンパク質（Ｅｐａｃ）の活性をモジュレートするための新規な化合物
|
|
JP2005533777A
(ja)
|
2002-06-17 |
2005-11-10 |
メルク エンド カムパニー インコーポレーテッド |
Ｒｎａ抗ウイルス剤としての炭素環ヌクレオシドアナログ
|
|
AU2003248708A1
(en)
|
2002-06-17 |
2003-12-31 |
Isis Pharmaceuticals, Inc. |
Oligomeric compounds that include carbocyclic nucleosides and their use in gene modulation
|
|
WO2004000858A2
(en)
|
2002-06-21 |
2003-12-31 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
|
EP1572945A2
(en)
|
2002-06-27 |
2005-09-14 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
|
AP2005003213A0
(en)
|
2002-06-28 |
2005-03-31 |
Univ Cagliari |
2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections.
|
|
TW200500375A
(en)
|
2002-06-28 |
2005-01-01 |
Idenix Cayman Ltd |
Modified 2' and 3'-nucleoside prodrugs for treating flaviviridae
|
|
WO2004003000A2
(en)
|
2002-06-28 |
2004-01-08 |
Idenix (Cayman) Limited |
1’-, 2'- and 3'- modified nucleoside derivatives for treating flaviviridae infections
|
|
EP1525183A1
(en)
|
2002-07-01 |
2005-04-27 |
Pharmacia & Upjohn Company LLC |
Inhibitors of hcv ns5b polymerase
|
|
US6973905B2
(en)
|
2002-07-01 |
2005-12-13 |
Cinetic Automation Corporation |
Valve lash adjustment apparatus and method
|
|
AU2003265255A1
(en)
|
2002-07-01 |
2004-01-19 |
Finzel, Barry, C. |
Inhibitors of hcv ns5b polymerase
|
|
WO2004007512A2
(en)
|
2002-07-16 |
2004-01-22 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
|
AU2003256619A1
(en)
|
2002-07-24 |
2004-02-09 |
Isis Pharmaceuticals, Inc. |
Pyrrolopyrimidine thionucleoside analogs as antivirals
|
|
CA2493816A1
(en)
|
2002-07-24 |
2004-01-29 |
Ptc Therapeutics, Inc. |
Use of nucleoside compounds for nonsense suppression and the treatment of genetic diseases
|
|
KR20050037559A
(ko)
|
2002-07-25 |
2005-04-22 |
마이크로로직스 바이오테크, 인코포레이티드 |
항바이러스성 ７-데아자 ｄ-뉴클레오시드 및 그의 용도
|
|
AU2003264038A1
(en)
|
2002-08-12 |
2004-02-25 |
Bristol-Myers Squibb Company |
Combination pharmaceutical agents as inhibitors of hcv replication
|
|
DK1572095T3
(en)
|
2002-09-13 |
2015-09-14 |
Novartis Ag |
BETA-L-2'-DEOXYNUCLEOTIDES FOR TREATMENT OF RESISTANT HBV STANDS AND COMBINATION THERAPIES
|
|
JP2006505571A
(ja)
|
2002-10-15 |
2006-02-16 |
リゲル ファーマシューテイカルズ、インコーポレイテッド |
置換されたインドール及びｈｃｖ阻害剤としてのその使用
|
|
US20040229840A1
(en)
|
2002-10-29 |
2004-11-18 |
Balkrishen Bhat |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
WO2004041201A2
(en)
|
2002-11-01 |
2004-05-21 |
Viropharma Incorporated |
Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases
|
|
US7824851B2
(en)
|
2002-11-15 |
2010-11-02 |
Idenix Pharmaceuticals, Inc. |
2′-branched nucleosides and Flaviviridae mutation
|
|
TWI332507B
(en)
|
2002-11-19 |
2010-11-01 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
|
AU2003296601A1
(en)
|
2002-12-10 |
2004-06-30 |
F. Hoffmann-La Roche Ag |
Antiviral nucleoside derivatives
|
|
MXPA05006230A
(es)
|
2002-12-12 |
2005-09-20 |
Idenix Cayman Ltd |
Proceso para la produccion de nucleosidos ramificados-2'.
|
|
AU2003300434A1
(en)
|
2002-12-23 |
2004-07-22 |
Idenix (Cayman) Limited |
Process for the production of 3'-nucleoside prodrugs
|
|
JP3658392B2
(ja)
|
2002-12-27 |
2005-06-08 |
キヤノン電子株式会社 |
信号出力装置及び信号出力装置を備えたシート材処理装置
|
|
SI1583542T1
(sl)
|
2003-01-14 |
2008-12-31 |
Gilead Sciences Inc |
Sestavki in postopki za kombinacijsko antivirusnoterapijo
|
|
US7223785B2
(en)
|
2003-01-22 |
2007-05-29 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
WO2004080466A1
(en)
|
2003-03-07 |
2004-09-23 |
Ribapharm Inc. |
Cytidine analogs and methods of use
|
|
WO2004084453A2
(en)
|
2003-03-20 |
2004-09-30 |
Microbiologica Quimica E Farmaceutica Ltd. |
METHODS OF MANUFACTURE OF 2'-DEOXY-β-L-NUCLEOSIDES
|
|
US20040202993A1
(en)
|
2003-04-10 |
2004-10-14 |
Poo Ramon E. |
Apparatus and method for organ preservation and transportation
|
|
EP1629000B1
(en)
|
2003-04-16 |
2009-02-18 |
Bristol-Myers Squibb Company |
Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus
|
|
CA2523083C
(en)
|
2003-04-25 |
2014-07-08 |
Gilead Sciences, Inc. |
Antiviral phosphonate analogs
|
|
US20050261237A1
(en)
|
2003-04-25 |
2005-11-24 |
Boojamra Constantine G |
Nucleoside phosphonate analogs
|
|
WO2005002626A2
(en)
|
2003-04-25 |
2005-01-13 |
Gilead Sciences, Inc. |
Therapeutic phosphonate compounds
|
|
US7452901B2
(en)
|
2003-04-25 |
2008-11-18 |
Gilead Sciences, Inc. |
Anti-cancer phosphonate analogs
|
|
JP2006524710A
(ja)
|
2003-04-25 |
2006-11-02 |
ギリアード サイエンシーズ， インコーポレイテッド |
キナーゼインヒビターホスホネート抱合体
|
|
BRPI0409680A
(pt)
|
2003-04-25 |
2006-04-18 |
Gilead Sciences Inc |
análogos de fosfonato anti-cáncer
|
|
US7470724B2
(en)
|
2003-04-25 |
2008-12-30 |
Gilead Sciences, Inc. |
Phosphonate compounds having immuno-modulatory activity
|
|
US7407965B2
(en)
|
2003-04-25 |
2008-08-05 |
Gilead Sciences, Inc. |
Phosphonate analogs for treating metabolic diseases
|
|
WO2004096210A1
(en)
|
2003-05-01 |
2004-11-11 |
Glaxo Group Limited |
Acylated indoline and tetrahydroquinoline derivatives as hcv inhibitors
|
|
US20040259934A1
(en)
|
2003-05-01 |
2004-12-23 |
Olsen David B. |
Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
|
|
WO2005020884A2
(en)
|
2003-05-14 |
2005-03-10 |
Idenix (Cayman) Limited |
Nucleosides for treatment of infection by corona viruses, toga viruses and picorna viruses
|
|
US20040229839A1
(en)
|
2003-05-14 |
2004-11-18 |
Biocryst Pharmaceuticals, Inc. |
Substituted nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
|
WO2004106356A1
(en)
|
2003-05-27 |
2004-12-09 |
Syddansk Universitet |
Functionalized nucleotide derivatives
|
|
CN100503628C
(zh)
*
|
2003-05-30 |
2009-06-24 |
法莫赛特股份有限公司 |
修饰的氟化核苷类似物
|
|
EP1644479A4
(en)
|
2003-06-16 |
2008-04-23 |
Mark W Grinstaff |
MACROMOLECULES AND FUNCTIONAL SYNTHETIC MOLECULES FOR GENES ADMINISTRATION
|
|
MXPA05013452A
(es)
|
2003-06-19 |
2006-03-09 |
Hoffmann La Roche |
Proceso para preparar derivados de 4'-azidonucleosido.
|
|
DE10331239A1
(de)
|
2003-07-10 |
2005-02-03 |
Robert Bosch Gmbh |
Überwachungselektronik für einen Elektromotor und Verfahren zur Überwachung eines Elektromotors
|
|
GB0317009D0
(en)
|
2003-07-21 |
2003-08-27 |
Univ Cardiff |
Chemical compounds
|
|
CN1852915A
(zh)
|
2003-07-25 |
2006-10-25 |
艾登尼科斯（开曼）有限公司 |
治疗包括丙型肝炎的黄病毒科病毒所致疾病的嘌呤核苷类似物
|
|
WO2005021568A2
(en)
|
2003-08-27 |
2005-03-10 |
Biota, Inc. |
Novel tricyclic nucleosides or nucleotides as therapeutic agents
|
|
WO2005028502A1
(en)
|
2003-09-18 |
2005-03-31 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
US20050148534A1
(en)
|
2003-09-22 |
2005-07-07 |
Castellino Angelo J. |
Small molecule compositions and methods for increasing drug efficiency using compositions thereof
|
|
HRP20130098T1
(hr)
|
2003-10-14 |
2013-02-28 |
F. Hoffmann - La Roche Ag |
MAKROCIKLIÄŚKE KARBOKSILNE KISELINE I ACILSULFONAMIDNI SPOJEVI KAO INHIBITORI REPLIKACIJE HCV-a
|
|
US7491794B2
(en)
|
2003-10-14 |
2009-02-17 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
|
MXPA06004680A
(es)
*
|
2003-10-27 |
2007-04-17 |
Genelabs Tech Inc |
Compuestos de nucleosido para el tratamiento de infecciones virales.
|
|
US7026339B2
(en)
|
2003-11-07 |
2006-04-11 |
Fan Yang |
Inhibitors of HCV NS5B polymerase
|
|
TW200528459A
(en)
|
2004-01-06 |
2005-09-01 |
Achillion Pharmaceuticals Inc |
Azabenzofuran substituted thioureas; inhibitors of viral replication
|
|
US20070155731A1
(en)
|
2004-01-28 |
2007-07-05 |
Gabor Butora |
Aminocyclopentyl pyridopyrazinone modulators of chemokine receptor activity
|
|
AU2005216971A1
(en)
|
2004-02-25 |
2005-09-09 |
Government Of The United States Of America, As Represented By The Secretary Department Of Health And Human Services Office Of Technology Transfer |
Methylation inhibitor compounds
|
|
CN100384237C
(zh)
|
2004-02-28 |
2008-04-23 |
鸿富锦精密工业（深圳）有限公司 |
音量调整装置及方法
|
|
WO2005087788A2
(en)
|
2004-03-04 |
2005-09-22 |
The Regents Of The University Of California |
Methods for preparation of nucleoside phosphonate esters
|
|
US8759317B2
(en)
|
2004-03-18 |
2014-06-24 |
University Of South Florida |
Method of treatment of cancer using guanosine 3′, 5′ cyclic monophosphate (cyclic GMP)
|
|
BRPI0509467A
(pt)
|
2004-03-30 |
2007-09-11 |
Intermune Inc |
compostos macrocìclicos como inibidores de replicação viral
|
|
GB0408995D0
(en)
|
2004-04-22 |
2004-05-26 |
Glaxo Group Ltd |
Compounds
|
|
US7534767B2
(en)
|
2004-06-15 |
2009-05-19 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase
|
|
AU2005256963A1
(en)
|
2004-06-23 |
2006-01-05 |
Centre National De La Recherche Scientifique |
5-aza-7-deazapurine derivatives for treating infections with flaviviridae
|
|
JP5080973B2
(ja)
*
|
2004-06-24 |
2012-11-21 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Ｒｎａ依存性ｒｎａウイルスの感染を処置するためのヌクレオシドアリールホスホルアミダート
|
|
US7217523B2
(en)
|
2004-07-02 |
2007-05-15 |
Regents Of The University Of Minnesota |
Nucleoside phosphoramidates and nucleoside phosphoramidases
|
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
CA2574651C
(en)
*
|
2004-07-21 |
2013-05-21 |
Pharmasset, Inc. |
Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives
|
|
PL216369B1
(pl)
|
2004-07-27 |
2014-03-31 |
Gilead Sciences |
Pochodne fosfonianowe, kompozycje farmaceutyczne zawierające te pochodne oraz zastosowanie tych pochodnych do wytwarzania leku do hamowania wirusa HIV
|
|
US7153848B2
(en)
|
2004-08-09 |
2006-12-26 |
Bristol-Myers Squibb Company |
Inhibitors of HCV replication
|
|
US7348425B2
(en)
|
2004-08-09 |
2008-03-25 |
Bristol-Myers Squibb Company |
Inhibitors of HCV replication
|
|
ATE437875T1
(de)
|
2004-08-23 |
2009-08-15 |
Hoffmann La Roche |
Heterozyklische antivirale verbindungen
|
|
CN101044151B
(zh)
|
2004-08-23 |
2011-01-19 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒的4＇-叠氮基-核苷
|
|
WO2006029081A2
(en)
|
2004-09-02 |
2006-03-16 |
Neopharm, Inc. |
Nucleoside-lipid conjugates, their method of preparation and uses thereof
|
|
BRPI0515279A
(pt)
|
2004-09-14 |
2008-07-15 |
Pharmasset Inc |
preparação de ribofuranosil pirimidinas e purinas 2'fluoro-2'-alquil- substituìdas ou outras opcionalmente substituìdas e seus derivados
|
|
BRPI0515896A
(pt)
|
2004-09-24 |
2008-08-12 |
Idenix Cayman Ltd E Ct Nat De |
composto ou um sal ou éster farmaceuticamente aceitável do mesmo, método para o tratamento ou profilaxia de um hospedeiro infectado com uma infecção por flavivìrus, pestivìrus ou hepacivìrus, e, composição farmacêutica para o tratamento de um hospedeiro infectado com uma infecção por flavivìrus, pestivìrus ou hepacivìrus
|
|
JP5046942B2
(ja)
|
2004-09-30 |
2012-10-10 |
テイボテク・フアーマシユーチカルズ |
Ｈｃｖ阻害性の二環式ピリミジン類
|
|
US20080280842A1
(en)
|
2004-10-21 |
2008-11-13 |
Merck & Co., Inc. |
Fluorinated Pyrrolo[2,3-D]Pyrimidine Nucleosides for the Treatment of Rna-Dependent Rna Viral Infection
|
|
KR20070100237A
(ko)
|
2004-10-29 |
2007-10-10 |
바이오크리스트 파마수티컬즈, 인코퍼레이티드 |
치료용 푸로피리미딘 및 티에노피리미딘
|
|
WO2006063149A1
(en)
|
2004-12-09 |
2006-06-15 |
Regents Of The University Of Minnesota |
Nucleosides with antiviral and anticancer activity
|
|
GB0427123D0
(en)
|
2004-12-11 |
2005-01-12 |
Apv Systems Ltd |
Food item coating apparatus and method
|
|
WO2006065590A2
(en)
|
2004-12-16 |
2006-06-22 |
Xtl Biopharmaceuticals Inc. |
Pyridine and pyrimidine antiviral compositions
|
|
WO2006063717A2
(en)
|
2004-12-16 |
2006-06-22 |
Febit Biotech Gmbh |
Polymerase-independent analysis of the sequence of polynucleotides
|
|
WO2006093801A1
(en)
|
2005-02-25 |
2006-09-08 |
Abbott Laboratories |
Thiadiazine derivatives useful as anti-infective agents
|
|
CA2597683A1
(en)
|
2005-02-28 |
2006-09-08 |
Genelabs Technologies, Inc. |
Tricyclic-nucleoside prodrugs for treating viral infections
|
|
US8802840B2
(en)
|
2005-03-08 |
2014-08-12 |
Biota Scientific Management Pty Ltd. |
Bicyclic nucleosides and nucleotides as therapeutic agents
|
|
GB0505781D0
(en)
|
2005-03-21 |
2005-04-27 |
Univ Cardiff |
Chemical compounds
|
|
AU2006226322B2
(en)
|
2005-03-25 |
2012-03-29 |
Tibotec Pharmaceuticals Ltd. |
Heterobicylic inhibitors of HCV
|
|
AR056327A1
(es)
|
2005-04-25 |
2007-10-03 |
Genelabs Tech Inc |
Compuestos de nucleosidos para el tratamiento de infecciones virales
|
|
TWI368621B
(en)
|
2005-05-02 |
2012-07-21 |
Leyoung Biotech Co Ltd |
Stereoselective synthesis of β-nucleosides
|
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
|
AR054122A1
(es)
|
2005-05-12 |
2007-06-06 |
Tibotec Pharm Ltd |
Pirido[2,3-d]pirimidas utiles como inhibidores de hcv, y metodos para la preparacion de las mismas
|
|
AR056347A1
(es)
|
2005-05-12 |
2007-10-03 |
Tibotec Pharm Ltd |
Uso de compuestos de pteridina para fabricar medicamentos y composiciones farmaceuticas
|
|
WO2007027248A2
(en)
*
|
2005-05-16 |
2007-03-08 |
Valeant Research & Development |
3', 5' - cyclic nucleoside analogues for treatment of hcv
|
|
US8143288B2
(en)
|
2005-06-06 |
2012-03-27 |
Bristol-Myers Squibb Company |
Inhibitors of HCV replication
|
|
TWI471145B
(zh)
|
2005-06-13 |
2015-02-01 |
Bristol Myers Squibb & Gilead Sciences Llc |
單一式藥學劑量型
|
|
TWI375560B
(en)
|
2005-06-13 |
2012-11-01 |
Gilead Sciences Inc |
Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
|
|
CA2610484A1
(en)
|
2005-06-22 |
2007-01-04 |
Biocryst Pharmaceuticals, Inc. |
Methods for the preparation of 9-deazapurine derivatives
|
|
US20060293752A1
(en)
|
2005-06-27 |
2006-12-28 |
Missoum Moumene |
Intervertebral disc prosthesis and associated methods
|
|
KR101294467B1
(ko)
|
2005-07-25 |
2013-09-09 |
인터뮨, 인크. |
Ｃ형 간염 바이러스 복제의 신규 거대고리형 억제제
|
|
CN101272769B
(zh)
|
2005-07-28 |
2013-04-24 |
Isp投资有限公司 |
生物利用度提高的苯醌类化合物
|
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
EP1919898B1
(en)
|
2005-07-29 |
2011-01-26 |
Tibotec Pharmaceuticals |
Macrocyclic inhibitors of hepatitis c virus
|
|
US20070059360A1
(en)
|
2005-07-29 |
2007-03-15 |
Ashish Jaiswal |
Water-dispersible anti-retroviral pharmaceutical compositions
|
|
TWI383980B
(zh)
|
2005-07-29 |
2013-02-01 |
Tibotec Pharm Ltd |
Ｃ型肝炎病毒之大環抑制劑
|
|
TWI393723B
(zh)
|
2005-07-29 |
2013-04-21 |
Tibotec Pharm Ltd |
Ｃ型肝炎病毒之大環抑制劑（九）
|
|
WO2007014925A1
(en)
|
2005-07-29 |
2007-02-08 |
Tibotec Pharmaceuticals Ltd. |
Macrocylic inhibitors of hepatitis c virus
|
|
CN101287472B
(zh)
|
2005-08-15 |
2011-10-12 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒的4'-取代前核苷酸的氨基磷酸酯类化合物
|
|
GB0519478D0
(en)
|
2005-09-23 |
2005-11-02 |
Glaxo Group Ltd |
Compounds
|
|
GB0519488D0
(en)
|
2005-09-23 |
2005-11-02 |
Glaxo Group Ltd |
Compounds
|
|
CA2623522C
(en)
|
2005-09-26 |
2015-12-08 |
Pharmasset, Inc. |
Modified 4'-nucleosides as antiviral agents
|
|
US7668209B2
(en)
|
2005-10-05 |
2010-02-23 |
Lg Electronics Inc. |
Method of processing traffic information and digital broadcast system
|
|
WO2007065829A1
(en)
|
2005-12-09 |
2007-06-14 |
F. Hoffmann-La Roche Ag |
Antiviral nucleosides
|
|
WO2007070556A2
(en)
|
2005-12-12 |
2007-06-21 |
Genelabs Technologies, Inc. |
N-(6-membered aromatic ring)-amido anti-viral compounds
|
|
NZ544187A
(en)
|
2005-12-15 |
2008-07-31 |
Ind Res Ltd |
Deazapurine analogs of 1'-aza-l-nucleosides
|
|
RU2441869C2
(ru)
|
2005-12-21 |
2012-02-10 |
Эбботт Лэборетриз |
Противовирусные соединения
|
|
GB0602046D0
(en)
|
2006-02-01 |
2006-03-15 |
Smithkline Beecham Corp |
Compounds
|
|
WO2007092000A1
(en)
|
2006-02-06 |
2007-08-16 |
Bristol-Myers Squibb Company |
Inhibitors of hcv replication
|
|
JP2009526850A
(ja)
|
2006-02-14 |
2009-07-23 |
メルク エンド カムパニー インコーポレーテッド |
Ｒｎａ依存性ｒｎａウイルス感染を治療するためのヌクレオシドアリールホスホルアミデート
|
|
JP2009528989A
(ja)
|
2006-02-17 |
2009-08-13 |
ファイザー・リミテッド |
Ｔｌｒ７変調剤としての３−デアザプリン誘導体
|
|
US8895531B2
(en)
|
2006-03-23 |
2014-11-25 |
Rfs Pharma Llc |
2′-fluoronucleoside phosphonates as antiviral agents
|
|
DE602007006796D1
(de)
|
2006-05-25 |
2010-07-08 |
Bristol Myers Squibb Co |
Cyclopropyl-fusionierte indolbenzazepin-hcv-ns5b-hemmer
|
|
PT2049506E
(pt)
|
2006-07-07 |
2015-10-09 |
Gilead Sciences Inc |
Moduladores de propriedades farmacocinéticas de agentes terapêuticos
|
|
US20080014228A1
(en)
|
2006-07-14 |
2008-01-17 |
Olivia Darmuzey |
Solid form
|
|
EP1881001A1
(en)
|
2006-07-20 |
2008-01-23 |
Tibotec Pharmaceuticals Ltd. |
HCV NS-3 serine protease inhibitors
|
|
TW200815384A
(en)
|
2006-08-25 |
2008-04-01 |
Viropharma Inc |
Combination therapy method for treating hepatitis C virus infection and pharmaceutical compositions for use therein
|
|
BRPI0719174A2
(pt)
|
2006-10-10 |
2017-06-13 |
Hoffmann La Roche |
preparação de pirimidinas ribofuranosil nucleosídeos
|
|
PL216525B1
(pl)
|
2006-10-17 |
2014-04-30 |
Ct Badań Molekularnych I Makromolekularnych Polskiej Akademii Nauk |
5'-O-[(N-acylo)amidoditiofosforano] nukleozydy oraz sposób wytwarzania 5'-O-[(N-acylo)amidofosforano]-,5'-O-[(N-acylo)amidotiofosforano]-, 5'-O-[(N-acylo)amidoditiofosforano]nukleozydów
|
|
GB0623493D0
(en)
*
|
2006-11-24 |
2007-01-03 |
Univ Cardiff |
Chemical compounds
|
|
AU2007338899A1
(en)
|
2006-12-20 |
2008-07-03 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside cyclic phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
|
US7951789B2
(en)
|
2006-12-28 |
2011-05-31 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
EP2124555B1
(en)
|
2007-01-05 |
2015-07-08 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
|
CN101765369A
(zh)
|
2007-03-19 |
2010-06-30 |
俄勒冈州由俄勒冈州立大学代表州高等教育委员会行使 |
曼尼希碱n-氧化物药物
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
GB0709791D0
(en)
|
2007-05-22 |
2007-06-27 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
|
CN100532388C
(zh)
|
2007-07-16 |
2009-08-26 |
郑州大学 |
2’-氟-4’-取代-核苷类似物、其制备方法及应用
|
|
CN101108870A
(zh)
|
2007-08-03 |
2008-01-23 |
冷一欣 |
核苷磷酸酯类化合物及制备方法和应用
|
|
EP2188296A1
(en)
|
2007-08-31 |
2010-05-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Compounds for inhibiting wip1, prodrugs and compositions thereof, and related methods
|
|
JO2778B1
(en)
|
2007-10-16 |
2014-03-15 |
ايساي انك |
Certain Compounds, Compositions and Methods
|
|
JP5238939B2
(ja)
|
2007-11-07 |
2013-07-17 |
三菱化学株式会社 |
長繊維強化複合樹脂組成物および成形品
|
|
US20090318380A1
(en)
|
2007-11-20 |
2009-12-24 |
Pharmasset, Inc. |
2',4'-substituted nucleosides as antiviral agents
|
|
US20090176732A1
(en)
|
2007-12-21 |
2009-07-09 |
Alios Biopharma Inc. |
Protected nucleotide analogs
|
|
US8227431B2
(en)
|
2008-03-17 |
2012-07-24 |
Hetero Drugs Limited |
Nucleoside derivatives
|
|
WO2009142822A2
(en)
|
2008-03-26 |
2009-11-26 |
Alnylam Pharmaceuticals, Inc. |
2-f modified rna interference agents
|
|
WO2009129120A2
(en)
|
2008-04-15 |
2009-10-22 |
Rfs Pharma, Llc |
Nucleoside derivatives for treatment of caliciviridae infections, including norovirus infections
|
|
AU2009240630B2
(en)
|
2008-04-23 |
2013-07-18 |
Gilead Sciences, Inc. |
Carba-nucleoside analogs for antiviral treatment
|
|
US7964560B2
(en)
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8173621B2
(en)
*
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
US20110229438A1
(en)
|
2008-10-09 |
2011-09-22 |
Anadys Pharmaceuticals, Inc. |
Method of inhibiting hepatitus c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds
|
|
EP2376515A1
(en)
|
2008-12-23 |
2011-10-19 |
Pharmasset, Inc. |
Synthesis of purine nucleosides
|
|
US8551973B2
(en)
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
CA2748057C
(en)
*
|
2008-12-23 |
2018-07-03 |
Pharmasset, Inc. |
Nucleoside phosphoramidates
|
|
AU2010203660A1
(en)
|
2009-01-07 |
2011-07-28 |
Scynexis, Inc |
Combination of a cyclosporine derivative and nucleosides for treating HCV
|
|
KR20110120886A
(ko)
|
2009-01-09 |
2011-11-04 |
유니버시티 칼리지 오브 카디프 컨설턴트 리미티드 |
바이러스 감염 치료용 구아노신 뉴클레오사이드 화합물의 포스포라미데이트 유도체
|
|
JO3027B1
(ar)
|
2009-05-14 |
2016-09-05 |
Janssen Products Lp |
نيوكليوسيدات يوراسيل سبيرواوكسيتان
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
TWI598358B
(zh)
|
2009-05-20 |
2017-09-11 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
US8719767B2
(en)
|
2011-03-31 |
2014-05-06 |
Commvault Systems, Inc. |
Utilizing snapshots to provide builds to developer computing devices
|
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
BR122021021135B1
(pt)
|
2009-09-21 |
2022-08-30 |
Gilead Sciences, Inc |
Compostos análogos de 2-flúor substituído carba-nucleosídeo, composição farmacêutica e uso dos compostos análogos de 2´-flúoro substituído carbonucleosídeo
|
|
CL2011000718A1
(es)
|
2010-03-31 |
2012-04-09 |
Gilead Pharmasset Llc |
Proceso para la preparacion de compuestos fosforados enantiomericos.
|
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
|
PT3042910T
(pt)
|
2010-11-30 |
2019-04-16 |
Gilead Pharmasset Llc |
2'-espiro-nucleósidos para utilização na terapia da hepatite c
|