JP2006514989A - 2,4−ピリミジンジアミン化合物による自己免疫疾患の治療および予防方法 - Google Patents
2,4−ピリミジンジアミン化合物による自己免疫疾患の治療および予防方法 Download PDFInfo
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- JP2006514989A JP2006514989A JP2005506142A JP2005506142A JP2006514989A JP 2006514989 A JP2006514989 A JP 2006514989A JP 2005506142 A JP2005506142 A JP 2005506142A JP 2005506142 A JP2005506142 A JP 2005506142A JP 2006514989 A JP2006514989 A JP 2006514989A
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
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- Vascular Medicine (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39967302P | 2002-07-29 | 2002-07-29 | |
US44394903P | 2003-01-31 | 2003-01-31 | |
US45233903P | 2003-03-06 | 2003-03-06 | |
PCT/US2003/024087 WO2004014382A1 (en) | 2002-07-29 | 2003-07-29 | Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds |
US10/631,029 US7517886B2 (en) | 2002-07-29 | 2003-07-29 | Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010152958A Division JP5441841B2 (ja) | 2002-07-29 | 2010-07-05 | 2,4−ピリミジンジアミン化合物による自己免疫疾患の処置または予防の方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006514989A true JP2006514989A (ja) | 2006-05-18 |
JP2006514989A5 JP2006514989A5 (US07825116-20101102-C00007.png) | 2010-08-19 |
Family
ID=31721742
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005506142A Pending JP2006514989A (ja) | 2002-07-29 | 2003-07-29 | 2,4−ピリミジンジアミン化合物による自己免疫疾患の治療および予防方法 |
JP2010152958A Expired - Fee Related JP5441841B2 (ja) | 2002-07-29 | 2010-07-05 | 2,4−ピリミジンジアミン化合物による自己免疫疾患の処置または予防の方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010152958A Expired - Fee Related JP5441841B2 (ja) | 2002-07-29 | 2010-07-05 | 2,4−ピリミジンジアミン化合物による自己免疫疾患の処置または予防の方法 |
Country Status (25)
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006508997A (ja) * | 2002-11-28 | 2006-03-16 | シエーリング アクチエンゲゼルシャフト | Chk−、Pdk−およびAkt−阻害性ピリミジン、それらの製造および薬剤としての使用 |
JP2006518356A (ja) * | 2003-02-20 | 2006-08-10 | テイボテク・フアーマシユーチカルズ・リミテツド | Hiv複製を阻害するピリミジンおよびトリアジン |
JP2007500179A (ja) * | 2003-07-30 | 2007-01-11 | サイクラセル・リミテッド | キナーゼ阻害剤としての2−アミノフェニル−4−フェニルピリミジン |
JP2007501793A (ja) * | 2003-08-07 | 2007-02-01 | リゲル ファーマシューティカルズ,インコーポレイティド | 抗増殖剤としての2,4−ピリミジンジアミン化合物および使用 |
JP2007502260A (ja) * | 2003-08-15 | 2007-02-08 | ノバルティス アクチエンゲゼルシャフト | 新生物疾患、炎症および免疫障害の処置に有用な2,4−ピリミジンジアミン |
JP2010524952A (ja) * | 2007-04-16 | 2010-07-22 | ハッチソン メディファーマ エンタープライジズ リミテッド | ピリミジン誘導体 |
JP2010526048A (ja) * | 2007-05-04 | 2010-07-29 | アストラゼネカ アクチボラグ | アミノ−チアゾリル−ピリミジン誘導体、および癌の治療のための該誘導体の使用 |
JP2010536846A (ja) * | 2007-08-17 | 2010-12-02 | エルジー・ライフ・サイエンシーズ・リミテッド | 細胞壊死阻害剤としてのインドール及びインダゾール化合物 |
JP2012514043A (ja) * | 2008-12-30 | 2012-06-21 | ライジェル ファーマシューティカルズ, インコーポレイテッド | ピリミジンジアミンキナーゼ阻害剤 |
JP2013511547A (ja) * | 2009-11-20 | 2013-04-04 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 2,4−ピリミジンジアミン化合物およびそのプロドラッグならびにそれらの使用 |
JP2013523891A (ja) * | 2010-04-13 | 2013-06-17 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 2,4−ピリミジンジアミン化合物およびそのプロドラッグならびにそれらの使用 |
JP2013526562A (ja) * | 2010-05-21 | 2013-06-24 | ケミリア・エービー | 新規ピリミジン誘導体 |
JPWO2014069510A1 (ja) * | 2012-10-31 | 2016-09-08 | 富山化学工業株式会社 | 新規アミン誘導体またはその塩 |
JP2017500326A (ja) * | 2013-12-19 | 2017-01-05 | バイエル・ファルマ・アクティエンゲゼルシャフト | 新規なインダゾールカルボキサミド、その調製法、これらを含む医薬製剤および医薬品を製造するためのその使用 |
JP2018524356A (ja) * | 2015-07-09 | 2018-08-30 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | Btk阻害剤としてのピリミジン誘導体及びその使用 |
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