CY1110292T1 - Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης - Google Patents

Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης

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Publication number
CY1110292T1
CY1110292T1 CY20101100217T CY101100217T CY1110292T1 CY 1110292 T1 CY1110292 T1 CY 1110292T1 CY 20101100217 T CY20101100217 T CY 20101100217T CY 101100217 T CY101100217 T CY 101100217T CY 1110292 T1 CY1110292 T1 CY 1110292T1
Authority
CY
Cyprus
Prior art keywords
treatment
methods
compounds
pyrimidinodymine
immune diseases
Prior art date
Application number
CY20101100217T
Other languages
English (en)
Inventor
Rajinder Singh
Ankush Argade
Donald G Payan
Jeffrey Clough
Holger Keim
Catherine Sylvain
Hui Li
Somasekhar Bhamidipati
Original Assignee
Rigel Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31721742&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110292(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rigel Pharmaceuticals, Inc. filed Critical Rigel Pharmaceuticals, Inc.
Publication of CY1110292T1 publication Critical patent/CY1110292T1/el

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

Η παρούσα εφεύρεση παρέχει μεθόδους για τη θεραπευτική αντιμετώπιση ή πρόληψη αυτοάνοσων νόσων με ενώσεις 2,4-πυριμιδινοδιαμίνης, καθώς και μεθόδους για τη θεραπευτική αντιμετώπιση, πρόληψη ή βελτίωση των συμπτωμάτων που συνδέονται με αυτές τις νόσους. Στα συγκεκριμένα παραδείγματα αυτοάνοσων νόσων που δύνανται να αντιμετωπιστούν θεραπευτικά ή να προληφθούν με τις ενώσεις συμπεριλαμβάνονται η ρευματοειδής αρθρίτιδα και/ή τα συνδεόμενα με αυτή συμπτώματα, ο συστηματικός ερυθηματώδης λύκος και/ή τα συνδεόμενα με αυτόν συμπτώματα και η σκλήρυνση κατά πλάκας και/ή τα συνδεόμενα με αυτή συμπτώματα.
CY20101100217T 2002-07-29 2010-03-09 Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης CY1110292T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39967302P 2002-07-29 2002-07-29
US44394903P 2003-01-31 2003-01-31
US45233903P 2003-03-06 2003-03-06
EP03784871A EP1534286B1 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
US10/631,029 US7517886B2 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds

Publications (1)

Publication Number Publication Date
CY1110292T1 true CY1110292T1 (el) 2015-01-14

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CY20101100217T CY1110292T1 (el) 2002-07-29 2010-03-09 Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης

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US (5) US7517886B2 (el)
EP (1) EP1534286B1 (el)
JP (2) JP2006514989A (el)
CN (2) CN103169708B (el)
AT (1) ATE451104T1 (el)
AU (1) AU2003265336B8 (el)
BR (1) BR0313059B8 (el)
CA (1) CA2492325C (el)
CY (1) CY1110292T1 (el)
DE (1) DE60330466D1 (el)
DK (1) DK1534286T3 (el)
ES (2) ES2337782T3 (el)
HK (2) HK1079978A1 (el)
HR (1) HRP20050089B1 (el)
IL (3) IL166241A0 (el)
IS (1) IS2923B (el)
MX (1) MXPA05001096A (el)
NO (1) NO332550B1 (el)
NZ (1) NZ537752A (el)
PL (1) PL216744B1 (el)
RS (1) RS51752B (el)
RU (1) RU2659777C9 (el)
SE (1) SE0500203L (el)
SG (1) SG176311A1 (el)
WO (1) WO2004014382A1 (el)

Families Citing this family (172)

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TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
ES2337782T3 (es) * 2002-07-29 2010-04-29 Rigel Pharmaceuticals, Inc. Metodos para tratar o prevenir enfermedades autoinmunitarias con compuestos de 2,4-pirimidindiamina.
US7504410B2 (en) * 2002-11-28 2009-03-17 Schering Aktiengesellschaft Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents
UA80767C2 (en) * 2002-12-20 2007-10-25 Pfizer Prod Inc Pyrimidine derivatives for the treatment of abnormal cell growth
CL2004000306A1 (es) * 2003-02-20 2005-04-08 Tibotec Pharm Ltd Compuestos derivados de pirimidina sustituidas con indano; proceso para su preparacion; composicion farmaceutica que lo comprende; combinacion farmaceutica; y su uso para el tratamiento o profilaxis de una enfermedad infecciosa.
BRPI0413018B8 (pt) * 2003-07-30 2021-05-25 Rigel Pharmaceuticals Inc composto, e, uso de um composto
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