NO20051069L - Fremgangsmater for behandling eller hindring av autoimmunsykdommer med 2,4-pyrimidindiaminforbindelser - Google Patents

Fremgangsmater for behandling eller hindring av autoimmunsykdommer med 2,4-pyrimidindiaminforbindelser

Info

Publication number
NO20051069L
NO20051069L NO20051069A NO20051069A NO20051069L NO 20051069 L NO20051069 L NO 20051069L NO 20051069 A NO20051069 A NO 20051069A NO 20051069 A NO20051069 A NO 20051069A NO 20051069 L NO20051069 L NO 20051069L
Authority
NO
Norway
Prior art keywords
treating
autoimmune diseases
methods
pyrimidinediamine compounds
preventing autoimmune
Prior art date
Application number
NO20051069A
Other languages
English (en)
Other versions
NO332550B1 (no
Inventor
Rajinder Singh
Ankush Argade
Donald G Payan
Jeffrey Clough
Holger Keim
Somasekhar Bhamidipati
Catherine Sylvain
Hui Li
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31721742&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20051069(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of NO20051069L publication Critical patent/NO20051069L/no
Publication of NO332550B1 publication Critical patent/NO332550B1/no

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
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  • Vascular Medicine (AREA)

Abstract

Denne oppfinnelsen inneholder metoder for behandling eller forebygging av autoimmune sykdommer med 2,4-pyrimidindiamin-forbindelser, i tillegg til metoder for behandling, forebygging eller forbedring av symptomer assosiert med slike sykdommer. Spesifikke eksempler på autoimmune sykdommer som kan behandles eller forebygges med forbindelsene er rheumatoid artritt og/eller symptomer som assosieres med dette, systemisk lupus erythematosus og/eller symptomer som assosieres med dette samt multippel sklerose og/eller symptomer som assosieres med dette.
NO20051069A 2002-07-29 2005-02-28 2,4-Pyrimidindiamin-forbindelser for anvendelse ved behandling av en autoimmun sykdom forskjellig fra ulcerativ kolitt, Crohn's sykdom, inflammatorisk tarm og idiopatisk inflammatorisk tarmsykdom NO332550B1 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39967302P 2002-07-29 2002-07-29
US44394903P 2003-01-31 2003-01-31
US45233903P 2003-03-06 2003-03-06
US10/631,029 US7517886B2 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
PCT/US2003/024087 WO2004014382A1 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds

Publications (2)

Publication Number Publication Date
NO20051069L true NO20051069L (no) 2005-02-28
NO332550B1 NO332550B1 (no) 2012-10-22

Family

ID=31721742

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051069A NO332550B1 (no) 2002-07-29 2005-02-28 2,4-Pyrimidindiamin-forbindelser for anvendelse ved behandling av en autoimmun sykdom forskjellig fra ulcerativ kolitt, Crohn's sykdom, inflammatorisk tarm og idiopatisk inflammatorisk tarmsykdom

Country Status (24)

Country Link
US (5) US7517886B2 (no)
EP (1) EP1534286B1 (no)
JP (2) JP2006514989A (no)
CN (2) CN1678321A (no)
AT (1) ATE451104T1 (no)
AU (1) AU2003265336B8 (no)
BR (1) BR0313059B8 (no)
CA (1) CA2492325C (no)
CY (1) CY1110292T1 (no)
DE (1) DE60330466D1 (no)
DK (1) DK1534286T3 (no)
ES (2) ES2445208T3 (no)
HR (1) HRP20050089B1 (no)
IL (3) IL166241A0 (no)
IS (1) IS2923B (no)
MX (1) MXPA05001096A (no)
NO (1) NO332550B1 (no)
NZ (1) NZ537752A (no)
PL (1) PL216744B1 (no)
RS (1) RS51752B (no)
RU (1) RU2659777C9 (no)
SE (1) SE0500203L (no)
SG (1) SG176311A1 (no)
WO (1) WO2004014382A1 (no)

Families Citing this family (184)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
IL166241A0 (en) * 2002-07-29 2006-01-15 Rigel Pharmaceuticals Inc Method of treating or preventing autoimmune diseases with 2,4-pyrimidinedinediamine compounds
WO2004048343A1 (en) * 2002-11-28 2004-06-10 Schering Aktiengesellschaft Chk-, pdk- and akt-inhibitory pyrimidines, their production and use as pharmaceutical agents
UA80767C2 (en) * 2002-12-20 2007-10-25 Pfizer Prod Inc Pyrimidine derivatives for the treatment of abnormal cell growth
CL2004000303A1 (es) * 2003-02-20 2005-04-08 Tibotec Pharm Ltd Compuestos derivados de pirimidinas y triazinas; proceso de preparacion; composicion farmaceutica; y su uso para inhibir la replicacion del vih.
EP1648875A1 (en) * 2003-07-30 2006-04-26 Cyclacel Limited 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
ES2421139T3 (es) * 2003-07-30 2013-08-29 Rigel Pharmaceuticals, Inc. Compuestos de 2,4-pirimidindiamina para su uso en el tratamiento o la prevención de enfermedades autoinmunitarias
DK1663242T3 (da) * 2003-08-07 2011-08-01 Rigel Pharmaceuticals Inc 2,4-Pyrimidindiamin-forbindelser og anvendelse som antiproliferative midler
ATE542801T1 (de) * 2003-08-15 2012-02-15 Novartis Ag Zur behandlung von neoplastischen krankheiten, entzündlichen erkrankungen und erkrankungen des immunsystems geeignete 2,4-pyrimidindiamine
AU2005231507B2 (en) 2004-04-08 2012-03-01 Targegen, Inc. Benzotriazine inhibitors of kinases
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