MX2013010898A - Novedoso derivados de la pirimidina. - Google Patents

Novedoso derivados de la pirimidina.

Info

Publication number
MX2013010898A
MX2013010898A MX2013010898A MX2013010898A MX2013010898A MX 2013010898 A MX2013010898 A MX 2013010898A MX 2013010898 A MX2013010898 A MX 2013010898A MX 2013010898 A MX2013010898 A MX 2013010898A MX 2013010898 A MX2013010898 A MX 2013010898A
Authority
MX
Mexico
Prior art keywords
pyrimidine derivatives
novel pyrimidine
compounds
methods
novel
Prior art date
Application number
MX2013010898A
Other languages
English (en)
Inventor
Tommy Johansson
Emma Dahlstedt
Olof Smitt
Marita Hoegberg
Original Assignee
Chemilia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP11159589A external-priority patent/EP2502924A1/en
Application filed by Chemilia Ab filed Critical Chemilia Ab
Publication of MX2013010898A publication Critical patent/MX2013010898A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La invención proporciona novedosos derivados de la pirimidina de fórmula 1, métodos de preparación de estos compuestos, composiciones farmacéuticas que contienen dichos compuestos y métodos para el uso de dichos compuestos en el tratamiento de enfermedades, incluyendo el cáncer (Ver Formula) en la cual R1-R11, Z, y Y son como defindos en la especificación.
MX2013010898A 2011-03-24 2012-03-23 Novedoso derivados de la pirimidina. MX2013010898A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11159589A EP2502924A1 (en) 2011-03-24 2011-03-24 Novel pyrimidine derivatives
EP11189572 2011-11-17
PCT/EP2012/055216 WO2012127032A1 (en) 2011-03-24 2012-03-23 Novel pyrimidine derivatives

Publications (1)

Publication Number Publication Date
MX2013010898A true MX2013010898A (es) 2013-12-06

Family

ID=45876788

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013010898A MX2013010898A (es) 2011-03-24 2012-03-23 Novedoso derivados de la pirimidina.

Country Status (12)

Country Link
US (1) US9006241B2 (es)
EP (1) EP2688883B1 (es)
JP (1) JP5886411B2 (es)
KR (1) KR20140006048A (es)
AU (1) AU2012230229A1 (es)
BR (1) BR112013024378A2 (es)
CA (1) CA2830129C (es)
DK (1) DK2688883T3 (es)
ES (1) ES2587864T3 (es)
MX (1) MX2013010898A (es)
RU (1) RU2013147417A (es)
WO (1) WO2012127032A1 (es)

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ES2929309T3 (es) 2017-05-18 2022-11-28 Idorsia Pharmaceuticals Ltd Derivados de benzofurano y benzotiofeno como moduladores del receptor PGE2
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US20140045845A1 (en) 2014-02-13
BR112013024378A2 (pt) 2016-12-13
ES2587864T3 (es) 2016-10-27
EP2688883A1 (en) 2014-01-29
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JP5886411B2 (ja) 2016-03-16
CA2830129C (en) 2016-07-19
DK2688883T3 (en) 2016-09-05
WO2012127032A1 (en) 2012-09-27
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CA2830129A1 (en) 2012-09-27
RU2013147417A (ru) 2015-04-27

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