HU226413B1
(en)
|
1991-06-25 |
2008-11-28 |
Aventis Pharma Sa |
Novel 16-(nitro-substituted methyl)pregna-1,4-dien-3,20-dion derivatives and process for producing them
|
DE4127404A1
(de)
|
1991-08-19 |
1993-02-25 |
Thomae Gmbh Dr K |
Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
US5491234A
(en)
|
1992-03-30 |
1996-02-13 |
Pfizer Inc. |
Pyrimidine derivatives for enhancing antitumor activity
|
ES2274634T3
(es)
|
1998-08-29 |
2007-05-16 |
Astrazeneca Ab |
Compuestos de pirimidina.
|
US7125875B2
(en)
|
1999-04-15 |
2006-10-24 |
Bristol-Myers Squibb Company |
Cyclic protein tyrosine kinase inhibitors
|
MXPA01010292A
(es)
|
1999-04-15 |
2002-10-23 |
Squibb Bristol Myers Co |
Inhibidores ciclicos de la proteina tirosina cinasa.
|
DE10007411A1
(de)
|
2000-02-18 |
2001-08-23 |
Bayer Ag |
Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
AU2006201264A1
(en)
|
2000-09-15 |
2006-04-27 |
Vertex Pharmaceuticals Incorporated |
Pyrazole Compounds Useful As Protein Kinase Inhibitors
|
US6660731B2
(en)
|
2000-09-15 |
2003-12-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
AU2006201262B2
(en)
|
2000-09-15 |
2008-09-04 |
Vertex Pharmaceuticals Incorporated |
Pyrazole Compounds Useful As Protein Kinase Inhibitors
|
US6613776B2
(en)
|
2000-09-15 |
2003-09-02 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
AU2006201263B2
(en)
|
2000-09-15 |
2008-10-30 |
Vertex Pharmaceuticals Incorporated |
Pyrazole Compounds Useful As Protein Kinase Inhibitors
|
AU2006201230B8
(en)
|
2000-09-15 |
2008-09-25 |
Vertex Pharmaceuticals Incorporated |
Triazole Compounds Useful As Protein Kinase Inhibitors
|
KR100876069B1
(ko)
|
2000-09-15 |
2008-12-26 |
버텍스 파마슈티칼스 인코포레이티드 |
단백질 키나제 억제제로서 유용한 피라졸 화합물 및 이를 포함하는 약제학적 조성물
|
AU2006201265B2
(en)
|
2000-09-15 |
2008-09-04 |
Vertex Pharmaceuticals Incorporated |
Pyrazole Compounds Useful As Protein Kinase Inhibitors
|
AU2006201229B2
(en)
|
2000-12-21 |
2008-11-20 |
Vertex Pharmaceuticals Incorporated |
Pyrazole Compounds Useful as Protein Kinase Inhibitors
|
MXPA03005610A
(es)
|
2000-12-21 |
2003-10-06 |
Vertex Pharma |
Compuestos de pirazol utiles como inhibidores de la proteina cinasa.
|
HU230574B1
(hu)
|
2000-12-21 |
2023-11-28 |
Novartis Ag |
Pirimidinamin-származékok és ezeket tartalmazó gyógyászati készítmények, mint angiogenézis modulátorok
|
CA2433018A1
(en)
|
2000-12-21 |
2002-06-27 |
Joel C. Barrish |
Thiazolyl inhibitors of tec family tyrosine kinases
|
US6881737B2
(en)
|
2001-04-11 |
2005-04-19 |
Amgen Inc. |
Substituted triazinyl acrylamide derivatives and methods of use
|
JP4291135B2
(ja)
|
2001-05-29 |
2009-07-08 |
バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト |
Cdk阻害性ピリミジン、それらの製造および薬剤としての使用
|
US6939874B2
(en)
|
2001-08-22 |
2005-09-06 |
Amgen Inc. |
Substituted pyrimidinyl derivatives and methods of use
|
US7115617B2
(en)
|
2001-08-22 |
2006-10-03 |
Amgen Inc. |
Amino-substituted pyrimidinyl derivatives and methods of use
|
US7868204B2
(en)
|
2001-09-14 |
2011-01-11 |
Methylgene Inc. |
Inhibitors of histone deacetylase
|
AU2006252047B2
(en)
|
2001-09-14 |
2010-02-11 |
Methylgene Inc. |
Inhibitors of histone deacetylase
|
BR0212510A
(pt)
|
2001-09-14 |
2004-08-24 |
Methylgene Inc |
Inibidor de histona desacetilase, composto e composição
|
US6897220B2
(en)
|
2001-09-14 |
2005-05-24 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
US7132423B2
(en)
|
2001-09-21 |
2006-11-07 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
US7163943B2
(en)
|
2001-09-21 |
2007-01-16 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
US7169785B2
(en)
|
2001-09-21 |
2007-01-30 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
US7173032B2
(en)
|
2001-09-21 |
2007-02-06 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
US7112587B2
(en)
|
2001-09-21 |
2006-09-26 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
WO2003030909A1
(en)
|
2001-09-25 |
2003-04-17 |
Bayer Pharmaceuticals Corporation |
2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer
|
WO2003026666A1
(en)
|
2001-09-26 |
2003-04-03 |
Bayer Pharmaceuticals Corporation |
2-phenylamino-4- (5-pyrazolylamino)-pyrimidine derivatives as kinase inhibitors, in particular, as src kinase inhibitors
|
WO2003040141A1
(en)
|
2001-09-28 |
2003-05-15 |
Bayer Pharmaceuticals Corporation |
Oxazolyl-phenyl-2,4-diamino-pyrimidine compounds and methods for treating hyperproliferative disorders
|
WO2003032997A1
(de)
|
2001-10-17 |
2003-04-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Pyrimidinderivate, arzneimittel enthaltend diese verbindungen, deren verwendung und verfahren zu ihrer herstellung
|
BR0213792A
(pt)
|
2001-11-01 |
2004-12-07 |
Janssen Pharmaceutica Nv |
Heteroaril aminas como inibidores de glicogênio sintase cinase 3beta (inibidores de gsk3)
|
ATE389638T1
(de)
|
2001-11-01 |
2008-04-15 |
Janssen Pharmaceutica Nv |
Aminobenzamidderivate als inhibitoren der glycogensynthasekinase-3-
|
SE0104140D0
(sv)
|
2001-12-07 |
2001-12-07 |
Astrazeneca Ab |
Novel Compounds
|
WO2003062227A1
(en)
|
2002-01-23 |
2003-07-31 |
Bayer Pharmaceuticals Corporation |
Rho-kinase inhibitors
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
CA2477505A1
(en)
|
2002-03-01 |
2003-09-12 |
Smithkline Beecham Corporation |
Diamino-pyrimidines and their use as angiogenesis inhibitors
|
AU2003225800A1
(en)
|
2002-03-15 |
2003-09-29 |
Hayley Binch |
Azolylaminoazine as inhibitors of protein kinases
|
ES2289279T3
(es)
|
2002-03-15 |
2008-02-01 |
Vertex Pharmaceuticals Incorporated |
Composiciones utiles como inhibidores de proteinquinasas.
|
WO2003095448A1
(en)
|
2002-05-06 |
2003-11-20 |
Bayer Pharmaceuticals Corporation |
Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders
|
SG176311A1
(en)
|
2002-07-29 |
2011-12-29 |
Rigel Pharmaceuticals |
Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
|
BR0313871A
(pt)
*
|
2002-08-30 |
2005-07-19 |
Eisai Co Ltd |
Derivados aromáticos contendo nitrogênio
|
US20040209930A1
(en)
|
2002-10-02 |
2004-10-21 |
Carboni Joan M. |
Synergistic methods and compositions for treating cancer
|
TW200501960A
(en)
|
2002-10-02 |
2005-01-16 |
Bristol Myers Squibb Co |
Synergistic kits and compositions for treating cancer
|
JP2006507302A
(ja)
|
2002-10-30 |
2006-03-02 |
メルク エンド カムパニー インコーポレーテッド |
キナーゼ阻害剤
|
JP2006508997A
(ja)
|
2002-11-28 |
2006-03-16 |
シエーリング アクチエンゲゼルシャフト |
Chk−、Pdk−およびAkt−阻害性ピリミジン、それらの製造および薬剤としての使用
|
ES2338545T3
(es)
|
2002-12-20 |
2010-05-10 |
Pfizer Products Inc. |
Derivados de pirimidina para el tratamiento del crecimiento celular anormal.
|
US7109337B2
(en)
|
2002-12-20 |
2006-09-19 |
Pfizer Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
UA80767C2
(en)
*
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
US7514446B2
(en)
|
2003-02-20 |
2009-04-07 |
Smithkline Beecham Corporation |
Pyrimidine compounds
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
NZ545058A
(en)
|
2003-07-16 |
2008-05-30 |
Janssen Pharmaceutica Nv |
Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors
|
JP2007526894A
(ja)
|
2003-07-16 |
2007-09-20 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
グリコーゲンシンターゼキナーゼ3インヒビターとしてのトリアゾロピリミジン誘導体
|
CN102358738A
(zh)
|
2003-07-30 |
2012-02-22 |
里格尔药品股份有限公司 |
2,4-嘧啶二胺化合物及其预防和治疗自体免疫疾病的用途
|
ATE455546T1
(de)
|
2003-08-06 |
2010-02-15 |
Vertex Pharma |
Aminotriazol-verbindungen als proteinkinase- hemmer
|
ATE506953T1
(de)
*
|
2003-08-07 |
2011-05-15 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidindiamin-verbindungen und verwendungen als antiproliferative mittel
|
JP4607879B2
(ja)
|
2003-08-15 |
2011-01-05 |
ノバルティス アーゲー |
新生物疾患、炎症および免疫障害の処置に有用な2,4−ピリミジンジアミン
|
WO2005023906A1
(ja)
|
2003-09-08 |
2005-03-17 |
Chugai Seiyaku Kabushiki Kaisha |
ヒアルロン酸修飾物、及びそれを用いた薬物担体
|
JP4205543B2
(ja)
|
2003-09-09 |
2009-01-07 |
本田技研工業株式会社 |
小型船
|
CN102060806A
(zh)
|
2003-09-11 |
2011-05-18 |
iTherX药品公司 |
细胞因子抑制剂
|
AU2004272288B2
(en)
|
2003-09-18 |
2008-11-13 |
Novartis Ag |
2,4-di (phenylamino) pyrimidines useful in the treatment of proliferative disorders
|
EP1683812B1
(en)
|
2003-11-14 |
2014-11-12 |
Chugai Seiyaku Kabushiki Kaisha |
Crosslinked polysaccharide microparticles and method for their preparation
|
PT1687297E
(pt)
|
2003-11-24 |
2014-09-18 |
Prometic Biosciences Inc |
Dímeros da triazina para o tratamento de doenças autoimunes
|
JP2007514775A
(ja)
|
2003-12-19 |
2007-06-07 |
ライジェル ファーマシューティカルズ, インコーポレイテッド |
1−(2,4−ピリミジンジアミノ)−2−シクロペンタンカルボキサイミド合成中間体の立体異性体および立体異性体混合物
|
US7253204B2
(en)
|
2004-03-26 |
2007-08-07 |
Methylgene Inc. |
Inhibitors of histone deacetylase
|
AU2005232745A1
(en)
|
2004-04-13 |
2005-10-27 |
Astellas Pharma Inc. |
Polycyclic pyrimidines as potassium ion channel modulators
|
US20060205945A1
(en)
|
2004-05-14 |
2006-09-14 |
Pfizer Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
EP1758887A1
(en)
|
2004-05-14 |
2007-03-07 |
Pfizer Products Incorporated |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
JP4812763B2
(ja)
|
2004-05-18 |
2011-11-09 |
ライジェル ファーマシューティカルズ, インコーポレイテッド |
シクロアルキル置換ピリミジンジアミン化合物およびそれらの用途
|
US20060051406A1
(en)
|
2004-07-23 |
2006-03-09 |
Manjeet Parmar |
Formulation of insoluble small molecule therapeutics in lipid-based carriers
|
US7521457B2
(en)
|
2004-08-20 |
2009-04-21 |
Boehringer Ingelheim International Gmbh |
Pyrimidines as PLK inhibitors
|
EP1786783A1
(en)
|
2004-09-01 |
2007-05-23 |
Rigel Pharmaceuticals, Inc. |
Synthesis of 2,4-pyrimidinediamine compounds
|
TW200612991A
(en)
|
2004-09-07 |
2006-05-01 |
Chugai Pharmaceutical Co Ltd |
Process for producing water-soluble hyaluronic acid modification
|
EP1806553A4
(en)
|
2004-10-28 |
2015-03-04 |
Sharp Kk |
COOLER
|
GB2420559B
(en)
|
2004-11-15 |
2008-08-06 |
Rigel Pharmaceuticals Inc |
Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
|
MY169441A
(en)
|
2004-12-08 |
2019-04-11 |
Janssen Pharmaceutica Nv |
2,4, (4,6) pyrimidine derivatives
|
CA2588220A1
(en)
|
2004-12-23 |
2006-06-29 |
Pfizer Products Inc. |
Heteroaromatic derivatives useful as anticancer agents
|
AU2005322855B2
(en)
|
2004-12-30 |
2012-09-20 |
Exelixis, Inc. |
Pyrimidine derivatives as kinase modulators and method of use
|
US7884109B2
(en)
|
2005-04-05 |
2011-02-08 |
Wyeth Llc |
Purine and imidazopyridine derivatives for immunosuppression
|
WO2006108103A1
(en)
|
2005-04-05 |
2006-10-12 |
Pharmacopeia, Inc. |
Purine and imidazopyridine derivatives for immunosuppression
|
DE102005016634A1
(de)
|
2005-04-12 |
2006-10-19 |
Merck Patent Gmbh |
Neuartige Aza-Hetercyclen als Kinase-Inhibitoren
|
US8227455B2
(en)
|
2005-04-18 |
2012-07-24 |
Rigel Pharmaceuticals, Inc. |
Methods of treating cell proliferative disorders
|
WO2006124874A2
(en)
|
2005-05-12 |
2006-11-23 |
Kalypsys, Inc. |
Inhibitors of b-raf kinase
|
ES2651349T3
(es)
|
2005-06-08 |
2018-01-25 |
Rigel Pharmaceuticals, Inc. |
Composiciones y métodos para la inhibición de la ruta JAK
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
AU2006269321A1
(en)
|
2005-07-08 |
2007-01-18 |
Ipsen Pharma S.A.S. |
Ligands of melanocortin receptors
|
MX2008000574A
(es)
|
2005-07-11 |
2008-03-14 |
Sanofi Aventis |
Nuevos derivados de 2,4-dianilinopirimidinas, la preparacion de los mismos, su uso como medicamentos, composiciones farmaceuticas y, en particular, como inhibidores ikk.
|
CA2614919C
(en)
|
2005-07-25 |
2015-06-23 |
Zachary Demko |
1, 2, 3 -triazoles inhibitors of tubulin polymerization for the treatment of proliferative disorders
|
US7486280B2
(en)
|
2005-08-04 |
2009-02-03 |
Uniplas Enterprises Pte, Ltd. |
Contoured capacitive touch control panel
|
KR100674813B1
(ko)
|
2005-08-05 |
2007-01-29 |
일양약품주식회사 |
N-페닐-2-피리미딘-아민 유도체 및 그의 제조방법
|
US20090118310A1
(en)
|
2005-08-09 |
2009-05-07 |
University Of Medicine And Dentistry Of New Jersey |
Activated Cdc42-associated kinase (ACK) as a therapeutic target for Ras-induced cancer
|
US20090124645A1
(en)
|
2005-10-14 |
2009-05-14 |
Neurosearch A/S |
Novel Pyrimidine-2,4-Diamine Derivatives and their Use as Modulators of Small-Conductance Calcium-Activated Potassium Channels
|
PT1951684T
(pt)
|
2005-11-01 |
2016-10-13 |
Targegen Inc |
Inibidores de cinases de tipo biaril-meta-pirimidina
|
US8604042B2
(en)
|
2005-11-01 |
2013-12-10 |
Targegen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
US8133900B2
(en)
|
2005-11-01 |
2012-03-13 |
Targegen, Inc. |
Use of bi-aryl meta-pyrimidine inhibitors of kinases
|
US8246984B2
(en)
|
2005-12-06 |
2012-08-21 |
Rigel Pharmaceuticals, Inc. |
Formulation of insoluble small molecule therapeutics in lipid-based carriers
|
NL2000323C2
(nl)
|
2005-12-20 |
2007-11-20 |
Pfizer Ltd |
Pyrimidine-derivaten.
|
US20070141684A1
(en)
|
2005-12-21 |
2007-06-21 |
Pfizer Inc |
Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
|
CA2634646C
(en)
|
2005-12-21 |
2012-04-10 |
Pfizer Products Inc. |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
US7962290B1
(en)
|
2006-01-09 |
2011-06-14 |
Rigel Pharmaceuticals, Inc. |
Identification of pharmacophores from co-crystals of spleen tyrosine kinase (SYK) and SYK ligands
|
TW200736232A
(en)
|
2006-01-26 |
2007-10-01 |
Astrazeneca Ab |
Pyrimidine derivatives
|
WO2007089768A2
(en)
|
2006-01-30 |
2007-08-09 |
Exelixis, Inc. |
4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrimidines as jak-2 modulators and pharmaceutical compositions containing them
|
JP2009528295A
(ja)
|
2006-02-24 |
2009-08-06 |
ライジェル ファーマシューティカルズ, インコーポレイテッド |
Jak経路の阻害のための組成物および方法
|
WO2007115999A1
(en)
|
2006-04-10 |
2007-10-18 |
Boehringer Ingelheim International Gmbh |
2, 4-diaminopyrimidine derivatives and their use for the treatment of cancer
|
CN101058561B
(zh)
|
2006-04-19 |
2011-01-26 |
苏州爱斯鹏药物研发有限责任公司 |
用于抑制蛋白激酶的二苯脲衍生物及其组合物和用途
|
EP2020231A4
(en)
|
2006-04-26 |
2010-11-10 |
Ito En Ltd |
FAT ABSORPTION INHIBITORS
|
WO2007130933A2
(en)
|
2006-05-01 |
2007-11-15 |
Jeffrey W Bezanson |
Apparatuses, methods and systems for vector operations and storage in matrix models
|
US7956185B2
(en)
|
2006-05-26 |
2011-06-07 |
Abbott Laboratories |
Cyclobut-3-ene-1,2,-dione inhibitors of polo-like kinases
|
US7460807B2
(en)
|
2006-05-31 |
2008-12-02 |
Kabushiki Kaisha Toshiba |
Image forming apparatus and method of controlling the apparatus
|
US20070293494A1
(en)
|
2006-06-15 |
2007-12-20 |
Djung Jane F |
2-Anilino-4-(Heterocyclic) Amino-Pyrimidines
|
EP2044063A1
(en)
|
2006-06-30 |
2009-04-08 |
Astra Zeneca AB |
Pyrimidine derivatives useful in the treatment of cancer
|
WO2008005538A2
(en)
|
2006-07-05 |
2008-01-10 |
Exelixis, Inc. |
Methods of using igf1r and abl kinase modulators
|
US8008307B2
(en)
|
2006-08-08 |
2011-08-30 |
Millennium Pharmaceuticals, Inc. |
Heteroaryl compounds useful as inhibitors of E1 activating enzymes
|
DE102006041382A1
(de)
|
2006-08-29 |
2008-03-20 |
Bayer Schering Pharma Ag |
Carbamoyl-Sulfoximide als Proteinkinaseinhibitoren
|
CN101679432B
(zh)
|
2006-10-19 |
2015-04-22 |
西格诺药品有限公司 |
杂芳基化合物、其组合物及其作为蛋白激酶抑制剂的用途
|
US20080119496A1
(en)
|
2006-11-16 |
2008-05-22 |
Pharmacopeia Drug Discovery, Inc. |
7-Substituted Purine Derivatives for Immunosuppression
|
UA100846C2
(uk)
|
2006-12-08 |
2013-02-11 |
Айерем Елелсі |
Сполуки та композиція як інгібітори протеїнкінази
|
WO2008076883A2
(en)
|
2006-12-15 |
2008-06-26 |
Abraxis Bioscience, Inc. |
Triazine derivatives and their therapeutical applications
|
WO2008082537A2
(en)
|
2006-12-19 |
2008-07-10 |
The General Hospital Corporation |
Compounds for modulating integrin cd11b/cd18
|
CN101563327A
(zh)
|
2006-12-19 |
2009-10-21 |
健泰科生物技术公司 |
嘧啶类激酶抑制剂
|
US20100298314A1
(en)
|
2006-12-20 |
2010-11-25 |
Schering Corporation |
Novel jnk inhibitors
|
EP1939185A1
(de)
|
2006-12-20 |
2008-07-02 |
Bayer Schering Pharma Aktiengesellschaft |
Neuartige Hetaryl-Phenylendiamin-Pyrimidine als Proteinkinaseinhibitoren zur Behandlung von Krebs
|
FR2911138B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
BRPI0807897A2
(pt)
|
2007-03-01 |
2014-06-17 |
Supergen Inc |
Derivados de pirimidina-2,4-diamina e seus usos como inibidores de jak2 quinase.
|
DK2134689T3
(da)
|
2007-03-16 |
2014-06-30 |
Scripps Research Inst |
Inhibitorer af fokal adhæsionskinase
|
US7947698B2
(en)
|
2007-03-23 |
2011-05-24 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
US7834024B2
(en)
|
2007-03-26 |
2010-11-16 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
WO2008124085A2
(en)
|
2007-04-03 |
2008-10-16 |
Exelixis, Inc. |
Methods of using combinations of mek and jak-2 inhibitors
|
TWI484960B
(zh)
|
2007-04-16 |
2015-05-21 |
Hutchison Medipharma Entpr Ltd |
嘧啶衍生物
|
CN101289444B
(zh)
|
2007-04-16 |
2012-01-04 |
和记黄埔医药(上海)有限公司 |
一种嘧啶衍生物及其医药用途
|
DK2146779T3
(en)
|
2007-04-18 |
2016-11-28 |
Pfizer Prod Inc |
Sulfonylamid derivatives to treat abnormal cell growth.
|
CL2008001626A1
(es)
|
2007-06-05 |
2009-06-05 |
Takeda Pharmaceuticals Co |
Compuestos derivados de heterociclos fusionados, agente farmaceutico que los comprende y su uso en la profilaxis y tratamiento del cancer.
|
EP2014657A1
(de)
|
2007-06-21 |
2009-01-14 |
Bayer Schering Pharma Aktiengesellschaft |
Diaminopyrimidine als Modulatoren des EP2-Rezeptors
|
US20090012045A1
(en)
|
2007-06-26 |
2009-01-08 |
Rigel Pharmaceuticals, Inc. |
Methods of Treating Cell Proliferative Disorders
|
JP2010533700A
(ja)
|
2007-07-16 |
2010-10-28 |
アストラゼネカ アクチボラグ |
ピリミジン誘導体
|
WO2009017838A2
(en)
|
2007-08-01 |
2009-02-05 |
Exelixis, Inc. |
Combinations of jak-2 inhibitors and other agents
|
FR2919869B1
(fr)
|
2007-08-09 |
2009-09-25 |
Sanofi Aventis Sa |
Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
CA2696824A1
(en)
|
2007-08-28 |
2009-03-12 |
Irm Llc |
Compounds and compositions as kinase inhibitors
|
WO2009028629A1
(ja)
|
2007-08-29 |
2009-03-05 |
Takeda Pharmaceutical Company Limited |
複素環化合物およびその用途
|
US7989465B2
(en)
|
2007-10-19 |
2011-08-02 |
Avila Therapeutics, Inc. |
4,6-disubstituted pyrimidines useful as kinase inhibitors
|
US7982036B2
(en)
|
2007-10-19 |
2011-07-19 |
Avila Therapeutics, Inc. |
4,6-disubstitued pyrimidines useful as kinase inhibitors
|
WO2009063240A1
(en)
|
2007-11-16 |
2009-05-22 |
Arrow Therapeutics Limited |
2,4-diaminopyrimidine derivatives useful as inhibitors of aurora kinase
|
EA019869B1
(ru)
|
2007-11-28 |
2014-06-30 |
Дана Фарбер Кансер Инститьют, Инк. |
Низкомолекулярные миристатные ингибиторы тирозинкиназы bcr-abl и способы их применения
|
US20090142832A1
(en)
|
2007-11-29 |
2009-06-04 |
James Dalton |
Indoles, Derivatives, and Analogs Thereof and Uses Therefor
|
JP2011505407A
(ja)
|
2007-12-03 |
2011-02-24 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
過剰な又は異常な細胞増殖を特徴とする疾患を治療するためのジアミノピリジン
|
PL2252300T3
(pl)
|
2008-02-22 |
2017-04-28 |
Rigel Pharmaceuticals, Inc. |
Zastosowanie 2,4-pirymidynodiamin do leczenia miażdżycy
|
CA2717529A1
(en)
|
2008-03-11 |
2009-09-17 |
Cellzome Limited |
Sulfonamides as zap-70 inhibitors
|
BRPI0914927B8
(pt)
|
2008-06-17 |
2021-05-25 |
Astrazeneca Ab |
composto, composição farmacêutica e uso de um composto
|
US8445505B2
(en)
|
2008-06-25 |
2013-05-21 |
Irm Llc |
Pyrimidine derivatives as kinase inhibitors
|
UY31929A
(es)
|
2008-06-25 |
2010-01-05 |
Irm Llc |
Compuestos y composiciones como inhibidores de cinasa
|
NZ624345A
(en)
|
2008-06-27 |
2016-07-29 |
Celgene Avilomics Res Inc |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
CN101684098A
(zh)
|
2008-09-24 |
2010-03-31 |
中国科学院上海药物研究所 |
一类5-脂氧酶抑制剂及其制备方法、药物组合物和应用
|
EP2241555A1
(en)
*
|
2009-04-14 |
2010-10-20 |
Universita' Degli Studi Di Milano |
New RAC1 inhibitors as potential pharmacological agents for heart failure treatment
|
JP2013523658A
(ja)
|
2010-03-26 |
2013-06-17 |
グラクソ グループ リミテッド |
キナーゼ阻害剤としてのピラゾリル‐ピリミジン
|
EP2552211A4
(en)
|
2010-03-26 |
2013-10-23 |
Glaxo Group Ltd |
INDAZOLYL-PYRIMIDINE AS KINASEHEMMER
|
JP2012209902A
(ja)
|
2011-03-30 |
2012-10-25 |
Semiconductor Components Industries Llc |
入出力回路
|