|
US6228871B1
(en)
|
1995-07-10 |
2001-05-08 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
GB9624482D0
(en)
*
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
US6184225B1
(en)
|
1996-02-13 |
2001-02-06 |
Zeneca Limited |
Quinazoline derivatives as VEGF inhibitors
|
|
DE69709319T2
(de)
|
1996-03-05 |
2002-08-14 |
Astrazeneca Ab, Soedertaelje |
4-anilinochinazolin derivate
|
|
ES2174250T5
(es)
|
1996-04-12 |
2010-04-21 |
Warner-Lambert Company Llc |
Inhibidores irreversibles de tirosina quinasas.
|
|
GB9707800D0
(en)
|
1996-05-06 |
1997-06-04 |
Zeneca Ltd |
Chemical compounds
|
|
US6124330A
(en)
|
1996-06-27 |
2000-09-26 |
Janssen-Cilag S.A. |
N-[4-(Heteroarylmethyl)phenyl]-heteroarylamines
|
|
EP0929526B1
(en)
|
1996-09-25 |
2005-07-27 |
AstraZeneca AB |
Qinoline derivatives inhibiting the effect of growth factors such as vegf
|
|
GB9718972D0
(en)
*
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
|
JP2009007364A
(ja)
*
|
1996-10-15 |
2009-01-15 |
Astrazeneca Uk Ltd |
キナゾリン誘導体
|
|
US6225318B1
(en)
|
1996-10-17 |
2001-05-01 |
Pfizer Inc |
4-aminoquinazolone derivatives
|
|
ZA986729B
(en)
*
|
1997-07-29 |
1999-02-02 |
Warner Lambert Co |
Irreversible inhibitors of tyrosine kinases
|
|
ATE368665T1
(de)
|
1997-08-22 |
2007-08-15 |
Astrazeneca Ab |
Oxindolylchinazolinderivate als angiogenesehemmer
|
|
US6465484B1
(en)
|
1997-09-26 |
2002-10-15 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
US6162804A
(en)
*
|
1997-09-26 |
2000-12-19 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
FR2772763B1
(fr)
*
|
1997-12-24 |
2004-01-23 |
Sod Conseils Rech Applic |
Nouveaux analogues tetracycliques de camptothecines, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
|
|
US6686366B1
(en)
|
1998-06-02 |
2004-02-03 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A3 receptor and uses thereof
|
|
US6878716B1
(en)
|
1998-06-02 |
2005-04-12 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A1 receptor and uses thereof
|
|
DZ2805A1
(fr)
|
1998-06-02 |
2005-01-30 |
Cadus Pharmaceutical Corp |
Composition à pyrroloÄ2,,3dÜ pyrimidine et leurs usages.
|
|
US7045519B2
(en)
|
1998-06-19 |
2006-05-16 |
Chiron Corporation |
Inhibitors of glycogen synthase kinase 3
|
|
US20040067227A1
(en)
*
|
2001-11-02 |
2004-04-08 |
Goldstein Allan L. |
Inhibition or reversal of skin aging by actin-sequestering peptides
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
|
JP3893026B2
(ja)
*
|
1999-02-10 |
2007-03-14 |
アストラゼネカ アクチボラグ |
血管形成阻害剤としてのキナゾリン誘導体
|
|
US6399743B1
(en)
|
1999-05-14 |
2002-06-04 |
Dept. Of Veterans Affairs |
Isolation and characterization of a rat epidermal growth factor related protein
|
|
US7049410B2
(en)
*
|
1999-05-14 |
2006-05-23 |
Majumdar Adhip P N |
Antibodies to a novel EGF-receptor related protein (ERRP)
|
|
MXPA01012899A
(es)
*
|
1999-06-21 |
2002-07-30 |
Boehringer Ingelheim Pharma |
Heterociclos biciclicos, medicamentos que contienen estos compuestos, su empleo y procedimientos para su preparacion.
|
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
|
WO2001021596A1
(en)
|
1999-09-21 |
2001-03-29 |
Astrazeneca Ab |
Quinazoline derivatives and their use as pharmaceuticals
|
|
CN1391561A
(zh)
*
|
1999-09-21 |
2003-01-15 |
阿斯特拉曾尼卡有限公司 |
喹唑啉化合物和含有喹唑啉化合物的药物组合物
|
|
SE9903544D0
(sv)
|
1999-10-01 |
1999-10-01 |
Astra Pharma Prod |
Novel compounds
|
|
ES2306306T3
(es)
|
1999-11-05 |
2008-11-01 |
Astrazeneca Ab |
Nuevos derivados de quinazolina.
|
|
UA74803C2
(uk)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
|
JP2003518023A
(ja)
|
1999-11-30 |
2003-06-03 |
パーカー ヒューズ インスティテュート |
トロンビン誘導血小板凝集の阻害剤
|
|
US6664252B2
(en)
|
1999-12-02 |
2003-12-16 |
Osi Pharmaceuticals, Inc. |
4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof
|
|
US6680322B2
(en)
|
1999-12-02 |
2004-01-20 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A1 receptors and uses thereof
|
|
US7160890B2
(en)
*
|
1999-12-02 |
2007-01-09 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A3 receptor and uses thereof
|
|
CA2398754A1
(en)
|
2000-02-07 |
2001-08-09 |
Abbott Gmbh & Co. Kg |
2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors
|
|
GB2359551A
(en)
|
2000-02-23 |
2001-08-29 |
Astrazeneca Uk Ltd |
Pharmaceutically active pyrimidine derivatives
|
|
AUPQ592100A0
(en)
*
|
2000-02-29 |
2000-03-23 |
Council Of The Queensland Institute Of Medical Research, The |
A method of treatment and prophylaxis
|
|
DE60112268T2
(de)
*
|
2000-03-06 |
2006-05-24 |
Astrazeneca Ab |
Verwendung von quinazolinderivate als inhibitoren der angiogenese
|
|
US20070021392A1
(en)
*
|
2000-03-31 |
2007-01-25 |
Davis Peter D |
Divided dose therapies with vascular damaging activity
|
|
GB0008269D0
(en)
*
|
2000-04-05 |
2000-05-24 |
Astrazeneca Ab |
Combination chemotherapy
|
|
ATE334973T1
(de)
|
2000-04-07 |
2006-08-15 |
Astrazeneca Ab |
Chinazolinverbindungen
|
|
RU2276151C2
(ru)
*
|
2000-06-06 |
2006-05-10 |
Астразенека Аб |
Хиназолиновые производные для лечения опухолей
|
|
UA73993C2
(uk)
*
|
2000-06-06 |
2005-10-17 |
Астразенека Аб |
Хіназолінові похідні для лікування пухлин та фармацевтична композиція
|
|
AR028948A1
(es)
|
2000-06-20 |
2003-05-28 |
Astrazeneca Ab |
Compuestos novedosos
|
|
EE05387B1
(et)
|
2000-08-21 |
2011-02-15 |
Astrazenecaab |
KinasoliiniÁderivaadid,ÁnendeÁvalmistamismeetodÁjaÁkasutamine
|
|
DE10042058A1
(de)
*
|
2000-08-26 |
2002-03-07 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
US6656946B2
(en)
|
2000-08-26 |
2003-12-02 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
|
|
WO2002018383A2
(en)
*
|
2000-09-01 |
2002-03-07 |
Chiron Corporation |
Aza heterocyclic derivatives and their therapeutic use
|
|
EA006711B1
(ru)
*
|
2000-09-11 |
2006-02-24 |
Чирон Корпорейшн |
Хинолиноновые производные в качестве ингибиторов тирозинкиназы
|
|
US20030028018A1
(en)
*
|
2000-09-11 |
2003-02-06 |
Chiron Coporation |
Quinolinone derivatives
|
|
SE0003828D0
(sv)
|
2000-10-20 |
2000-10-20 |
Astrazeneca Ab |
Novel compounds
|
|
WO2002036587A2
(en)
|
2000-11-01 |
2002-05-10 |
Cor Therapeutics, Inc. |
Process for the production of 4-quinazolinylpiperazin-1-carboxylic acid phenylamides
|
|
WO2002043735A1
(en)
*
|
2000-11-29 |
2002-06-06 |
Parker Hughes Institute |
Inhibitors of thrombin induced platelet aggregation
|
|
US6673802B2
(en)
|
2000-12-01 |
2004-01-06 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A3 receptor and uses thereof
|
|
US6680324B2
(en)
|
2000-12-01 |
2004-01-20 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A1 receptors and uses thereof
|
|
US7019012B2
(en)
|
2000-12-20 |
2006-03-28 |
Boehringer Ingelheim International Pharma Gmbh & Co. Kg |
Quinazoline derivatives and pharmaceutical compositions containing them
|
|
MXPA03005696A
(es)
|
2000-12-21 |
2003-10-06 |
Glaxo Group Ltd |
Pirimidinaminas como moduladores de angiogenesis.
|
|
JP2004531217A
(ja)
|
2001-01-05 |
2004-10-14 |
ファイザー・インク |
インスリン様成長因子ｉ受容体に対する抗体
|
|
US20070050857A1
(en)
*
|
2001-02-28 |
2007-03-01 |
Hayward Nick K |
Method of treatment and prophylaxis
|
|
MXPA03008560A
(es)
|
2001-03-22 |
2004-06-30 |
Abbot Gmbh & Co Kg |
Pirazolopirimidinas como agentes terapeuticos.
|
|
WO2002092578A1
(en)
*
|
2001-05-14 |
2002-11-21 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
WO2003000194A2
(en)
|
2001-06-21 |
2003-01-03 |
Pfizer Inc. |
Thienopyridine and thienopyrimidine anticancer agents
|
|
AU2002350105A1
(en)
|
2001-06-21 |
2003-01-08 |
Ariad Pharmaceuticals, Inc. |
Novel quinazolines and uses thereof
|
|
JP4836368B2
(ja)
*
|
2001-08-30 |
2011-12-14 |
広栄化学工業株式会社 |
メチルヒドロキシアルキルピリジン類の製造方法
|
|
GB0126433D0
(en)
*
|
2001-11-03 |
2002-01-02 |
Astrazeneca Ab |
Compounds
|
|
MXPA04004219A
(es)
*
|
2001-11-03 |
2004-09-10 |
Astrazeneca Ab |
Derivados de quinazolina como agentes antitumorales.
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
ATE446298T1
(de)
*
|
2001-11-30 |
2009-11-15 |
Osi Pharm Inc |
Verbindungen, die für adenosin a1 und a3 rezeptoren spezifisch sind, und deren anwendungen
|
|
US7232903B2
(en)
*
|
2001-12-19 |
2007-06-19 |
Ube Industries, Ltd. |
Process for producing quinazolin-4-one and derivatives thereof
|
|
EA007468B1
(ru)
|
2001-12-20 |
2006-10-27 |
Оси Фармасьютикалз, Инк. |
Пиримидиновые соединения, относящиеся к a-селективным антагонистам, их синтез и применение
|
|
US20030229067A1
(en)
*
|
2001-12-20 |
2003-12-11 |
Arlindo Castelhano |
Pyrrolopyrimidine A2b selective antagonist compounds, their synthesis and use
|
|
JP4389204B2
(ja)
*
|
2002-01-28 |
2009-12-24 |
宇部興産株式会社 |
キナゾリン−４−オン誘導体の製造方法
|
|
JP4608215B2
(ja)
*
|
2002-02-01 |
2011-01-12 |
アストラゼネカ アクチボラグ |
キナゾリン化合物
|
|
AU2003206068A1
(en)
|
2002-03-01 |
2003-09-16 |
Pfizer Inc. |
Indolyl-urea derivatives of thienopyridines useful as anti-angiogenic agents
|
|
TW200813014A
(en)
*
|
2002-03-28 |
2008-03-16 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
|
DE10221018A1
(de)
*
|
2002-05-11 |
2003-11-27 |
Boehringer Ingelheim Pharma |
Verwendung von Hemmern der EGFR-vermittelten Signaltransduktion zur Behandlung von gutartiger Prostatahyperplasie (BPH)/Prostatahypertrophie
|
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
|
US6936641B2
(en)
*
|
2002-06-25 |
2005-08-30 |
Johnson & Johnson Vision Care, Inc. |
Macromer forming catalysts
|
|
WO2004006846A2
(en)
|
2002-07-15 |
2004-01-22 |
Exelixis, Inc. |
Receptor-type kinase modulators and methods of use
|
|
GB0217431D0
(en)
|
2002-07-27 |
2002-09-04 |
Astrazeneca Ab |
Novel compounds
|
|
EP1548008A4
(en)
*
|
2002-08-23 |
2008-08-06 |
Kirin Pharma Kk |
COMPOUND WITH TGF-BETA-HEMMENDER EFFECT AND THIS MEDICAL COMPOSITION CONTAINING
|
|
US20050256157A1
(en)
*
|
2002-08-23 |
2005-11-17 |
Chiron Corporation |
Combination therapy with CHK1 inhibitors
|
|
KR20050037585A
(ko)
*
|
2002-08-23 |
2005-04-22 |
카이론 코포레이션 |
벤지미다졸 퀴놀리논 및 그들의 사용
|
|
US7825132B2
(en)
*
|
2002-08-23 |
2010-11-02 |
Novartis Vaccines And Diagnostics, Inc. |
Inhibition of FGFR3 and treatment of multiple myeloma
|
|
ES2295685T3
(es)
|
2002-08-24 |
2008-04-16 |
Astrazeneca Ab |
Derivados de pirimidina como moduladores de la actividad del receptor de quimioquinas.
|
|
GB0221828D0
(en)
|
2002-09-20 |
2002-10-30 |
Astrazeneca Ab |
Novel compound
|
|
MXPA05004858A
(es)
*
|
2002-11-04 |
2005-07-22 |
Astrazeneca Ab |
Derivados de quinazolina como inhibidores de cinasa de tirosina de src.
|
|
WO2004043389A2
(en)
*
|
2002-11-13 |
2004-05-27 |
Chiron Corporation |
Methods of treating cancer and related methods
|
|
EP1585743B1
(en)
|
2002-12-19 |
2007-05-23 |
Pfizer Inc. |
2-(1h-indazol-6-ylamino)- benzamide compounds as protein kinases inhibitors useful for the treatment of ophthalmic diseases
|
|
EP1578755B1
(en)
|
2002-12-24 |
2007-08-22 |
AstraZeneca AB |
Phosphonooxy quinazoline derivatives and their pharmaceutical use
|
|
US7223749B2
(en)
*
|
2003-02-20 |
2007-05-29 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
|
|
MXPA05009063A
(es)
|
2003-02-26 |
2005-12-12 |
Sugen Inc |
Compuestos de aminoheteroarilo como inhibidores de proteina cinasa.
|
|
GB0309009D0
(en)
*
|
2003-04-22 |
2003-05-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
GB0309850D0
(en)
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
SE0301569D0
(sv)
|
2003-05-27 |
2003-05-27 |
Astrazeneca Ab |
Novel compounds
|
|
GB0317665D0
(en)
|
2003-07-29 |
2003-09-03 |
Astrazeneca Ab |
Qinazoline derivatives
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
GB0318423D0
(en)
*
|
2003-08-06 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
|
NZ617083A
(en)
|
2003-08-27 |
2015-04-24 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders
|
|
EP1660504B1
(en)
|
2003-08-29 |
2008-10-29 |
Pfizer Inc. |
Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
GB0321648D0
(en)
*
|
2003-09-16 |
2003-10-15 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
DK1667991T3
(da)
|
2003-09-16 |
2008-08-18 |
Astrazeneca Ab |
Quinazolinderivater som tyrosinkinaseinhibitorer
|
|
BRPI0414447A
(pt)
*
|
2003-09-16 |
2006-11-14 |
Astrazeneca Ab |
derivado de quinazolina, composição farmacêutica, e, processo para a preparação de um derivado de quinazolina
|
|
UA83252C2
(uk)
*
|
2003-09-19 |
2008-06-25 |
Астразенека Аб |
Похідні хіназоліну, спосіб їх одержання (варіанти), фармацевтична композиція на їх основі, проміжна сполука
|
|
JP2007505878A
(ja)
*
|
2003-09-19 |
2007-03-15 |
アストラゼネカ アクチボラグ |
キナゾリン誘導体
|
|
AU2004276055A1
(en)
*
|
2003-09-25 |
2005-04-07 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
SI2392564T1
(sl)
*
|
2003-09-26 |
2014-02-28 |
Exelixis, Inc. |
c-Met modulatorji in postopki uporabe
|
|
US7456189B2
(en)
|
2003-09-30 |
2008-11-25 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
|
|
WO2005037836A2
(en)
|
2003-10-15 |
2005-04-28 |
Osi Pharmaceuticals, Inc. |
Imidazo ‘1, 5 - a ! pyrazine tyrosine kinase inhibitors
|
|
EA012621B1
(ru)
*
|
2003-11-07 |
2009-10-30 |
Чирон Корпорейшн |
Фармацевтически приемлемые соли хинолиноновых соединений с улучшенными фармацевтическими свойствами
|
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
ZA200604580B
(en)
|
2003-11-19 |
2009-08-26 |
Array Biopharma Inc |
Heterocyclic inhibitors of Mek and methods of use thereof
|
|
GB0328243D0
(en)
|
2003-12-05 |
2004-01-07 |
Astrazeneca Ab |
Methods
|
|
AU2004309166B2
(en)
|
2003-12-23 |
2008-02-21 |
Pfizer Inc. |
Novel quinoline derivatives
|
|
GB0330002D0
(en)
|
2003-12-24 |
2004-01-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
RU2397168C2
(ru)
|
2004-01-05 |
2010-08-20 |
Астразенека Аб |
Производные тиофена в качестве ингибиторов снк 1
|
|
US7435823B2
(en)
*
|
2004-01-23 |
2008-10-14 |
Amgen Inc. |
Compounds and methods of use
|
|
TW200538120A
(en)
*
|
2004-02-20 |
2005-12-01 |
Kirin Brewery |
Compound having TGF-beta inhibitory activity and pharmaceutical composition containing same
|
|
EP1718306A2
(en)
*
|
2004-02-20 |
2006-11-08 |
Chiron Corporation |
Modulation of inflammatory and metastatic processes
|
|
MY143225A
(en)
*
|
2004-04-02 |
2011-03-31 |
Osi Pharm Inc |
6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
|
|
RS52119B
(sr)
|
2004-05-06 |
2012-08-31 |
Warner-Lambert Company Llc |
4-fenilamino-hinazolin-6-il-amidi
|
|
AU2005250224A1
(en)
*
|
2004-06-04 |
2005-12-15 |
Astrazeneca Ab |
Quinazoline derivatives as ERBB receptor tyrosine kinases
|
|
SE0401657D0
(sv)
|
2004-06-24 |
2004-06-24 |
Astrazeneca Ab |
Chemical compounds
|
|
CA2573821A1
(en)
|
2004-07-16 |
2006-01-26 |
Pfizer Products Inc. |
Combination treatment for non-hematologic malignancies using an anti-igf-1r antibody
|
|
TW200613306A
(en)
|
2004-07-20 |
2006-05-01 |
Osi Pharm Inc |
Imidazotriazines as protein kinase inhibitors
|
|
RU2408587C2
(ru)
|
2004-08-24 |
2011-01-10 |
Астразенека Аб |
Производные пиримидинсульфонамида в качестве модуляторов рецепторов хемокинов
|
|
CN101023064B
(zh)
|
2004-08-26 |
2011-02-16 |
辉瑞大药厂 |
作为蛋白激酶抑制剂的对映异构体纯的氨基杂芳基化合物
|
|
EP1827434B1
(en)
|
2004-11-30 |
2014-01-15 |
Amgen Inc. |
Quinolines and quinazoline analogs and their use as medicaments for treating cancer
|
|
EP1838712B8
(en)
|
2004-12-14 |
2011-10-12 |
AstraZeneca AB |
Pyrazolopyrimidine compounds as antitumor agents
|
|
CN105085678B
(zh)
|
2004-12-21 |
2019-05-07 |
阿斯利康公司 |
血管生成素-2的抗体及其应用
|
|
GB0428526D0
(en)
|
2004-12-30 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
|
AU2006208012B2
(en)
*
|
2005-01-27 |
2011-08-04 |
Novartis Vaccines And Diagnostics Inc. |
Treatment of metastasized tumors
|
|
SI1846394T1
(sl)
|
2005-02-04 |
2012-06-29 |
Astrazeneca Ab |
Pirazolilaminopiridinski derivati uporabni kot kinazni inhibitorji
|
|
US8202879B2
(en)
*
|
2005-02-23 |
2012-06-19 |
Shionogi & Co., Ltd. |
Quinazoline derivatives having tyrosine kinase inhibitory activity
|
|
KR20070107151A
(ko)
*
|
2005-02-26 |
2007-11-06 |
아스트라제네카 아베 |
티로신 키나제 억제제로서의 퀴나졸린 유도체
|
|
GB0504474D0
(en)
*
|
2005-03-04 |
2005-04-13 |
Astrazeneca Ab |
Chemical compounds
|
|
EP1863848A4
(en)
|
2005-03-31 |
2009-09-23 |
Agensys Inc |
CORRESPONDING ANTIBODIES AND MOLECULES THAT ATTACH PROTEINS 161P2F10B
|
|
CA2604357C
(en)
|
2005-04-26 |
2012-01-17 |
Pfizer Inc. |
P-cadherin antibodies
|
|
JO2787B1
(en)
|
2005-04-27 |
2014-03-15 |
امجين إنك, |
Alternative amide derivatives and methods of use
|
|
GB0508717D0
(en)
*
|
2005-04-29 |
2005-06-08 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0508715D0
(en)
*
|
2005-04-29 |
2005-06-08 |
Astrazeneca Ab |
Chemical compounds
|
|
CN1858040B
(zh)
*
|
2005-05-08 |
2011-04-06 |
中国科学院上海药物研究所 |
5,8-二取代喹唑啉及其制备方法和用途
|
|
AU2006247803B2
(en)
|
2005-05-13 |
2011-12-22 |
Novartis Ag |
Methods for treating drug resistant cancer
|
|
WO2006125130A1
(en)
|
2005-05-17 |
2006-11-23 |
Novartis Ag |
Methods for synthesizing heterocyclic compounds
|
|
CN102321030A
(zh)
|
2005-05-18 |
2012-01-18 |
阵列生物制药公司 |
Mek的杂环抑制剂及其使用方法
|
|
EP2266974A1
(en)
|
2005-05-23 |
2010-12-29 |
Novartis AG |
Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-Quinolin-2-one lactic acid salts
|
|
RU2291706C1
(ru)
*
|
2005-06-21 |
2007-01-20 |
Автономная некоммерческая организация Научно-технический центр "Фармбиопресс" |
Применение флаволигнанов для подавления избыточной и патологической пролиферации эндотелия сосудов
|
|
WO2007011293A1
(en)
|
2005-07-21 |
2007-01-25 |
Astrazeneca Ab |
Novel piperidine derivatives
|
|
TW200738634A
(en)
|
2005-08-02 |
2007-10-16 |
Astrazeneca Ab |
New salt
|
|
US7566721B2
(en)
*
|
2005-08-08 |
2009-07-28 |
Osi Pharmaceuticals, Inc. |
Substituted thienol[2,3-d]pyrimidines as kinase inhibitors
|
|
TW200738658A
(en)
|
2005-08-09 |
2007-10-16 |
Astrazeneca Ab |
Novel compounds
|
|
HUE025608T2
(en)
|
2005-09-07 |
2016-03-29 |
Amgen Fremont Inc |
Human monoclonal antibody against activin receptor-like kinase-1 (ALK-1)
|
|
JP5055284B2
(ja)
|
2005-09-20 |
2012-10-24 |
オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー |
インシュリン様成長因子−１受容体キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー
|
|
US7820683B2
(en)
|
2005-09-20 |
2010-10-26 |
Astrazeneca Ab |
4-(1H-indazol-5-yl-amino)-quinazoline compounds as erbB receptor tyrosine kinase inhibitors for the treatment of cancer
|
|
US20090239861A1
(en)
*
|
2005-09-20 |
2009-09-24 |
Robert Hugh Bradbury |
Quinazoline derivatives as anticancer agents
|
|
WO2007034882A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
|
WO2007034916A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
|
US20090192153A1
(en)
|
2005-09-22 |
2009-07-30 |
Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan |
Novel adenine compound
|
|
JPWO2007034917A1
(ja)
|
2005-09-22 |
2009-03-26 |
大日本住友製薬株式会社 |
新規なアデニン化合物
|
|
GB0519879D0
(en)
|
2005-09-30 |
2005-11-09 |
Astrazeneca Ab |
Chemical process
|
|
US8148572B2
(en)
|
2005-10-06 |
2012-04-03 |
Astrazeneca Ab |
Compounds
|
|
WO2007049041A1
(en)
|
2005-10-28 |
2007-05-03 |
Astrazeneca Ab |
4- (3-aminopyrazole) pyrimidine derivatives for use as tyrosine kinase inhibitors in the treatment of cancer
|
|
CA2833706C
(en)
|
2005-11-11 |
2014-10-21 |
Boehringer Ingelheim International Gmbh |
Quinazoline derivatives for the treatment of cancer diseases
|
|
PT2090575E
(pt)
|
2005-11-15 |
2011-06-06 |
Array Biopharma Inc |
Inibidores de erbb
|
|
MY148529A
(en)
|
2005-11-29 |
2013-04-30 |
Novartis Ag |
Formulations of quinolinones
|
|
AR057960A1
(es)
*
|
2005-12-02 |
2007-12-26 |
Osi Pharm Inc |
Inhibidores de proteina quinasa biciclicos
|
|
ATE443053T1
(de)
*
|
2005-12-02 |
2009-10-15 |
Astrazeneca Ab |
Als inhibitoren von erbb-tyrosinkinase verwendete chinazoleinderivate
|
|
WO2007063291A1
(en)
*
|
2005-12-02 |
2007-06-07 |
Astrazeneca Ab |
4-anilino-substituted quinazoline derivatives as tyrosine kinase inhibitors
|
|
TW200730512A
(en)
|
2005-12-12 |
2007-08-16 |
Astrazeneca Ab |
Novel compounds
|
|
RU2492185C2
(ru)
|
2005-12-13 |
2013-09-10 |
Астразенека Аб |
Связывающие протеины, специфичные по отношению к инсулин-подобным факторам роста, и их использование
|
|
ATE545637T1
(de)
|
2005-12-15 |
2012-03-15 |
Astrazeneca Ab |
Substituierte diphenylether, -amine, -sulfide und methane zur behandlung von atemwegserkrankungen
|
|
US8575164B2
(en)
*
|
2005-12-19 |
2013-11-05 |
OSI Pharmaceuticals, LLC |
Combination cancer therapy
|
|
US20070231298A1
(en)
*
|
2006-03-31 |
2007-10-04 |
Cell Genesys, Inc. |
Cytokine-expressing cancer immunotherapy combinations
|
|
TW200813091A
(en)
|
2006-04-10 |
2008-03-16 |
Amgen Fremont Inc |
Targeted binding agents directed to uPAR and uses thereof
|
|
EP2021338A1
(en)
|
2006-05-09 |
2009-02-11 |
Pfizer Products Inc. |
Cycloalkylamino acid derivatives and pharmaceutical compositions thereof
|
|
JP2009538289A
(ja)
|
2006-05-26 |
2009-11-05 |
アストラゼネカ・アクチエボラーグ |
ビアリールまたはヘテロアリール置換インドール
|
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
|
DE102006037478A1
(de)
|
2006-08-10 |
2008-02-14 |
Merck Patent Gmbh |
2-(Heterocyclylbenzyl)-pyridazinonderivate
|
|
RS55881B1
(sr)
|
2006-08-23 |
2017-08-31 |
Kudos Pharm Ltd |
2-metilmorfolin pirido-,pirazo- i pirimido-pirimidin derivati kao inhibitori mtor-a
|
|
MX2009002710A
(es)
*
|
2006-09-18 |
2009-03-25 |
Boehringer Ingelheim Int |
Metodos para tratar canceres que portan mutaciones de egfr.
|
|
CL2007003158A1
(es)
*
|
2006-11-02 |
2008-05-16 |
Astrazeneca Ab |
Procedimiento de preparacion de compuestos derivados de quinazolina o sus sales farmaceuticamente aceptables; compuestos intermediarios; procedimiento de preparacion.
|
|
EP1921070A1
(de)
|
2006-11-10 |
2008-05-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung
|
|
TW200825084A
(en)
|
2006-11-14 |
2008-06-16 |
Astrazeneca Ab |
New compounds 521
|
|
US7799954B2
(en)
|
2006-11-17 |
2010-09-21 |
Abraxis Bioscience, Llc |
Dicarbonyl derivatives and methods of use
|
|
TW200831528A
(en)
|
2006-11-30 |
2008-08-01 |
Astrazeneca Ab |
Compounds
|
|
RU2009120229A
(ru)
|
2006-12-19 |
2011-01-27 |
Астразенека Аб (Se) |
Производные хинуклидинола в качестве антагонистов мускариновых рецепторов
|
|
CL2008000191A1
(es)
|
2007-01-25 |
2008-08-22 |
Astrazeneca Ab |
Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
|
|
AU2008212999A1
(en)
|
2007-02-06 |
2008-08-14 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
|
|
US20080190689A1
(en)
*
|
2007-02-12 |
2008-08-14 |
Ballard Ebbin C |
Inserts for engine exhaust systems
|
|
US8148532B2
(en)
|
2007-03-14 |
2012-04-03 |
Guoqing Paul Chen |
Spiro substituted compounds as angiogenesis inhibitors
|
|
PE20081887A1
(es)
|
2007-03-20 |
2009-01-16 |
Dainippon Sumitomo Pharma Co |
Nuevo compuesto de adenina
|
|
EP2138497A4
(en)
|
2007-03-20 |
2012-01-04 |
Dainippon Sumitomo Pharma Co |
NEW ADENINE CONNECTION
|
|
UA99459C2
(en)
|
2007-05-04 |
2012-08-27 |
Астразенека Аб |
9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer
|
|
DE102007025717A1
(de)
|
2007-06-01 |
2008-12-11 |
Merck Patent Gmbh |
Arylether-pyridazinonderivate
|
|
DE102007025718A1
(de)
|
2007-06-01 |
2008-12-04 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
DE102007026341A1
(de)
|
2007-06-06 |
2008-12-11 |
Merck Patent Gmbh |
Benzoxazolonderivate
|
|
UA100983C2
(ru)
|
2007-07-05 |
2013-02-25 |
Астразенека Аб |
Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
|
|
DE102007032507A1
(de)
|
2007-07-12 |
2009-04-02 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
DE102007038957A1
(de)
|
2007-08-17 |
2009-02-19 |
Merck Patent Gmbh |
6-Thioxo-pyridazinderivate
|
|
DE102007041115A1
(de)
|
2007-08-30 |
2009-03-05 |
Merck Patent Gmbh |
Thiadiazinonderivate
|
|
CA2698287A1
(en)
|
2007-09-07 |
2009-03-12 |
Agensys, Inc. |
Antibodies and related molecules that bind to 24p4c12 proteins
|
|
BRPI0817941A2
(pt)
|
2007-10-04 |
2015-05-05 |
Astrazeneca Ab |
Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide
|
|
BRPI0818533B8
(pt)
|
2007-10-11 |
2021-05-25 |
Astrazeneca Ab |
composto, composição farmacêutica, uso de um composto, e, processo para a preparação de um composto
|
|
RU2441004C1
(ru)
|
2007-12-19 |
2012-01-27 |
Дженентек, Инк. |
5-анилиноимидазопиридины и способы их применения
|
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
|
WO2009081201A2
(en)
|
2007-12-21 |
2009-07-02 |
Medimmune Limited |
BINDING MEMBERS FOR INTERLEUKIN-4 RECEPTOR ALPHA (IL-4Rα) - 173
|
|
KR20100099185A
(ko)
|
2007-12-21 |
2010-09-10 |
제넨테크, 인크. |
아자인돌리진 및 이용 방법
|
|
DE102007061963A1
(de)
|
2007-12-21 |
2009-06-25 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
JP2011510018A
(ja)
*
|
2008-01-18 |
2011-03-31 |
オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド |
癌治療のためのイミダゾピラジノール誘導体
|
|
WO2009094216A1
(en)
*
|
2008-01-22 |
2009-07-30 |
Concert Pharmaceuticals Inc. |
Derivatives of gefitinib
|
|
WO2009094210A1
(en)
*
|
2008-01-22 |
2009-07-30 |
Concert Pharmaceuticals Inc. |
Vandetanib derivatives
|
|
BRPI0907916A2
(pt)
|
2008-02-07 |
2015-07-28 |
Boehringer Ingelheim Int |
Heterociclos espirociclos, medicamentos contendo esses compostos, e processos para preparar os mesmos
|
|
EP2254889B1
(en)
|
2008-02-28 |
2012-12-19 |
Merck Patent GmbH |
Protein kinase inhibitors and use thereof
|
|
DE102008019907A1
(de)
|
2008-04-21 |
2009-10-22 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
JP5739802B2
(ja)
|
2008-05-13 |
2015-06-24 |
アストラゼネカ アクチボラグ |
４−（３−クロロ−２−フルオロアニリノ）−７−メトキシ−６−｛［１−（ｎ−メチルカルバモイルメチル）ピペリジン−４−イル］オキシ｝キナゾリンのフマル酸塩
|
|
EP2283020B8
(en)
*
|
2008-05-19 |
2012-12-12 |
OSI Pharmaceuticals, LLC |
Substituted imidazopyr-and imidazotri-azines
|
|
JP5607032B2
(ja)
|
2008-05-27 |
2014-10-15 |
アストラゼネカ・アクチエボラーグ |
フェノキシピリジニルアミド誘導体およびｐｄｅ４仲介疾患状態におけるその使用
|
|
DE102008025750A1
(de)
|
2008-05-29 |
2009-12-03 |
Merck Patent Gmbh |
Dihydropyrazolderivate
|
|
DE102008028905A1
(de)
|
2008-06-18 |
2009-12-24 |
Merck Patent Gmbh |
3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo[4,3-b]pyridazinderivate
|
|
DE102008029734A1
(de)
|
2008-06-23 |
2009-12-24 |
Merck Patent Gmbh |
Thiazolyl-piperidinderivate
|
|
UY31952A
(es)
|
2008-07-02 |
2010-01-29 |
Astrazeneca Ab |
5-metilideno-1,3-tiazolidina-2,4-dionas sustituidas como inhibidores de quinasa pim
|
|
JP5539351B2
(ja)
|
2008-08-08 |
2014-07-02 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
シクロヘキシルオキシ置換ヘテロ環、これらの化合物を含有する医薬、およびそれらを生成するための方法
|
|
DE102008037790A1
(de)
|
2008-08-14 |
2010-02-18 |
Merck Patent Gmbh |
Bicyclische Triazolderivate
|
|
DE102008038221A1
(de)
|
2008-08-18 |
2010-02-25 |
Merck Patent Gmbh |
7-Azaindolderivate
|
|
US8211911B2
(en)
|
2008-08-19 |
2012-07-03 |
Guoqing Paul Chen |
Compounds as kinase inhibitors
|
|
CN102264763B
(zh)
|
2008-09-19 |
2016-04-27 |
米迪缪尼有限公司 |
定向于dll4的抗体及其用途
|
|
JP5836125B2
(ja)
|
2008-10-16 |
2015-12-24 |
ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション |
高分子量メラノーマ関連抗原に対する完全ヒト抗体およびその使用
|
|
DE102008052943A1
(de)
|
2008-10-23 |
2010-04-29 |
Merck Patent Gmbh |
Azaindolderivate
|
|
WO2010067102A1
(en)
|
2008-12-09 |
2010-06-17 |
Astrazeneca Ab |
Diazaspiro [5.5] undecane derivatives and related compounds as muscarinic-receptor antagonists and beta-adrenoreceptor agonists for the treatment of pulmonary disorders
|
|
US7863325B2
(en)
|
2008-12-11 |
2011-01-04 |
Axcentua Pharmaceuticals Ab |
Crystalline genistein sodium salt dihydrate
|
|
US9012495B2
(en)
|
2008-12-11 |
2015-04-21 |
Axcentua Pharmaceuticals Ab |
Crystalline forms of genistein
|
|
US20100152197A1
(en)
|
2008-12-15 |
2010-06-17 |
Astrazeneca Ab |
(4-tert-butylpiperazin-2-yl)(piperazin-1-yl)methanone-n-carboxamide derivatives
|
|
JP2012512246A
(ja)
|
2008-12-17 |
2012-05-31 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｃ環修飾型三環式ベンゾナフチリジノン・タンパク質キナーゼ阻害薬及びこれらの使用
|
|
DE102008063667A1
(de)
|
2008-12-18 |
2010-07-01 |
Merck Patent Gmbh |
3-(3-Pyrimidin-2-yl-benzyl)-°[1,2,4]triazolo[4,3-b]pyrimidin-derivate
|
|
WO2010080253A1
(en)
|
2008-12-18 |
2010-07-15 |
Merck Patent Gmbh |
Tricyclic azaindoles
|
|
EP2379595A2
(en)
|
2008-12-23 |
2011-10-26 |
AstraZeneca AB |
Targeted binding agents directed to 5 1 and uses thereof
|
|
DE102008062825A1
(de)
|
2008-12-23 |
2010-06-24 |
Merck Patent Gmbh |
3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo [4,3-b]pyridazin-derivate
|
|
DE102008062826A1
(de)
|
2008-12-23 |
2010-07-01 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
DE102009003975A1
(de)
|
2009-01-07 |
2010-07-08 |
Merck Patent Gmbh |
Benzothiazolonderivate
|
|
DE102009003954A1
(de)
|
2009-01-07 |
2010-07-08 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
DE102009004061A1
(de)
|
2009-01-08 |
2010-07-15 |
Merck Patent Gmbh |
Pyridazinonderivate
|
|
NZ779754A
(en)
|
2009-01-16 |
2023-04-28 |
Exelixis Inc |
Malate salt of n-(4-{ [6,7-bis(methyloxy)quinolin-4-yl] oxy} phenyl)-n’-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer
|
|
JP5977522B2
(ja)
|
2009-02-05 |
2016-08-24 |
イミュノジェン・インコーポレーテッド |
新規ベンゾジアゼピン誘導体
|
|
WO2010089580A1
(en)
|
2009-02-06 |
2010-08-12 |
Astrazeneca Ab |
Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
|
|
WO2010090764A1
(en)
|
2009-02-09 |
2010-08-12 |
Supergen, Inc. |
Pyrrolopyrimidinyl axl kinase inhibitors
|
|
EP2396333B1
(en)
|
2009-02-10 |
2013-07-03 |
AstraZeneca AB |
Triazolo[4,3-b]pyridazine derivatives and their uses for prostate cancer
|
|
WO2010099139A2
(en)
|
2009-02-25 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Combination anti-cancer therapy
|
|
WO2010099137A2
(en)
|
2009-02-26 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
In situ methods for monitoring the emt status of tumor cells in vivo
|
|
WO2010098866A1
(en)
|
2009-02-27 |
2010-09-02 |
Supergen, Inc. |
Cyclopentathiophene/cyclohexathiophene dna methyltransferase inhibitors
|
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
JP2012519281A
(ja)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法
|
|
JP2012519282A
(ja)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法
|
|
GB0905127D0
(en)
|
2009-03-25 |
2009-05-06 |
Pharminox Ltd |
Novel prodrugs
|
|
UY32520A
(es)
|
2009-04-03 |
2010-10-29 |
Astrazeneca Ab |
Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
|
|
US8513415B2
(en)
|
2009-04-20 |
2013-08-20 |
OSI Pharmaceuticals, LLC |
Preparation of C-pyrazine-methylamines
|
|
WO2010129740A1
(en)
*
|
2009-05-07 |
2010-11-11 |
Osi Pharmaceuticals, Inc. |
Use of osi-906 for treating adrenocortical carcinoma
|
|
RU2404783C1
(ru)
*
|
2009-05-20 |
2010-11-27 |
Общество с ограниченной ответственностью "Лигфарм" |
Антиангиогенное лекарственное средство и способ его получения
|
|
US8389580B2
(en)
|
2009-06-02 |
2013-03-05 |
Duke University |
Arylcyclopropylamines and methods of use
|
|
US20100317593A1
(en)
|
2009-06-12 |
2010-12-16 |
Astrazeneca Ab |
2,3-dihydro-1h-indene compounds
|
|
JP5963672B2
(ja)
|
2009-07-06 |
2016-08-03 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｂｉｂｗ２９９２、その塩及びこの活性成分を含む固体医薬製剤の乾燥方法
|
|
BR112012000735A2
(pt)
|
2009-07-13 |
2016-11-16 |
Genentech Inc |
"métodos, kits e conjuntos de compostos"
|
|
GB0913342D0
(en)
|
2009-07-31 |
2009-09-16 |
Astrazeneca Ab |
Compounds - 801
|
|
WO2011014726A1
(en)
|
2009-07-31 |
2011-02-03 |
Osi Pharmaceuticals, Inc. |
Mtor inhibitor and angiogenesis inhibitor combination therapy
|
|
UA108618C2
(uk)
|
2009-08-07 |
2015-05-25 |
|
Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку
|
|
WO2011027249A2
(en)
|
2009-09-01 |
2011-03-10 |
Pfizer Inc. |
Benzimidazole derivatives
|
|
SG179070A1
(en)
|
2009-09-11 |
2012-04-27 |
Genentech Inc |
Method to identify a patient with an increased likelihood of responding to an anti-cancer agent
|
|
JP5606537B2
(ja)
|
2009-09-17 |
2014-10-15 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
癌患者における診断使用のための方法及び組成物
|
|
DE102009043260A1
(de)
|
2009-09-28 |
2011-04-28 |
Merck Patent Gmbh |
Pyridinyl-imidazolonderivate
|
|
MX2012003644A
(es)
|
2009-10-02 |
2012-04-30 |
Astrazeneca Ab |
Compuestos de 2-piridona empleados como inhibidores de la elastasa neutrofila.
|
|
DE102009049679A1
(de)
|
2009-10-19 |
2011-04-21 |
Merck Patent Gmbh |
Pyrazolopyrimidinderivate
|
|
WO2011048409A1
(en)
|
2009-10-20 |
2011-04-28 |
Astrazeneca Ab |
Cyclic amine derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
|
|
US8399460B2
(en)
|
2009-10-27 |
2013-03-19 |
Astrazeneca Ab |
Chromenone derivatives
|
|
WO2011051478A1
(en)
|
2009-10-30 |
2011-05-05 |
Domain Therapeutics |
Novel oxime derivatives and their use as allosteric modulators of metabotropic glutamate receptors
|
|
MX2012005329A
(es)
|
2009-11-18 |
2012-05-29 |
Astrazeneca Ab |
Compuestos benzoimidazolicos y sus usos.
|
|
HUE037159T2
(hu)
|
2009-11-24 |
2018-08-28 |
Medimmune Ltd |
Targetált kötõdõ ágensek B7-H1 ellen
|
|
EP2507237A1
(en)
|
2009-12-03 |
2012-10-10 |
Dainippon Sumitomo Pharma Co., Ltd. |
Imidazoquinolines which act via toll - like receptors (tlr)
|
|
WO2011072791A1
(de)
|
2009-12-14 |
2011-06-23 |
Merck Patent Gmbh |
Inhibitoren der sphingosinkinase
|
|
DE102009058280A1
(de)
|
2009-12-14 |
2011-06-16 |
Merck Patent Gmbh |
Thiazolderivate
|
|
WO2011073521A1
(en)
|
2009-12-15 |
2011-06-23 |
Petri Salven |
Methods for enriching adult-derived endothelial progenitor cells and uses thereof
|
|
CA2784647A1
(en)
|
2009-12-17 |
2011-07-14 |
Merck Patent Gmbh |
Inhibitors of sphingosine kinase
|
|
EP3296313B1
(en)
|
2010-01-15 |
2020-12-16 |
Suzhou Neupharma Co., Ltd |
Certain chemical entities, compositions, and methods
|
|
AU2011208530A1
(en)
|
2010-01-19 |
2012-08-09 |
Astrazeneca Ab |
Pyrazine derivatives
|
|
WO2011095807A1
(en)
|
2010-02-07 |
2011-08-11 |
Astrazeneca Ab |
Combinations of mek and hh inhibitors
|
|
US9173961B2
(en)
|
2010-02-10 |
2015-11-03 |
Immunogen, Inc. |
CD20 antibodies and uses thereof
|
|
PL3150610T3
(pl)
|
2010-02-12 |
2020-02-28 |
Pfizer Inc. |
Sole i polimorfy 8-fluoro-2-{4-[(metyloamino}metylo]fenylo}-1,3,4,5-tetrahydro-6Hazepino[5,4,3-cd]indol-6-onu
|
|
WO2011109584A2
(en)
|
2010-03-03 |
2011-09-09 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
|
JP2013527748A
(ja)
|
2010-03-03 |
2013-07-04 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
インスリン様増殖因子１受容体キナーゼ阻害剤に対する抗癌反応の予測に役立つ生物学的マーカー
|
|
WO2011114148A1
(en)
|
2010-03-17 |
2011-09-22 |
Astrazeneca Ab |
4h- [1, 2, 4] triazolo [5, 1 -b] pyrimidin-7 -one derivatives as ccr2b receptor antagonists
|
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
|
WO2011154677A1
(en)
|
2010-06-09 |
2011-12-15 |
Astrazeneca Ab |
Substituted n-[1-cyano-2-(phenyl)ethyl] 1-aminocycloalk-1-ylcarboxamide compounds - 760
|
|
GB201009801D0
(en)
|
2010-06-11 |
2010-07-21 |
Astrazeneca Ab |
Compounds 950
|
|
AU2011268356B2
(en)
|
2010-06-16 |
2013-09-19 |
University Of Pittsburgh-Of The Commonwealth System Of Higher Education |
Antibodies to endoplasmin and their use
|
|
BR112013001429A2
(pt)
|
2010-07-19 |
2016-05-31 |
Hoffmann La Roche |
método de identificação de pacientes com maior probabilidade de responder a terapia anticâncer
|
|
RU2013104039A
(ru)
|
2010-07-19 |
2014-08-27 |
Ф. Хоффманн-Ля Рош Аг |
Способ идентификации пациента с повышенной вероятностью ответа на противораковую терапию
|
|
AU2011280969A1
(en)
|
2010-07-23 |
2013-02-07 |
Trustees Of Boston University |
Anti-Despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
|
|
UY33539A
(es)
|
2010-08-02 |
2012-02-29 |
Astrazeneca Ab |
Compuestos químicos alk
|
|
TWI535712B
(zh)
|
2010-08-06 |
2016-06-01 |
阿斯特捷利康公司 |
化合物
|
|
DE102010034699A1
(de)
|
2010-08-18 |
2012-02-23 |
Merck Patent Gmbh |
Pyrimidinderivate
|
|
CN102656179B
(zh)
|
2010-08-28 |
2015-07-29 |
苏州润新生物科技有限公司 |
蟾蜍灵衍生物、其药物组合物及用途
|
|
WO2012042421A1
(en)
|
2010-09-29 |
2012-04-05 |
Pfizer Inc. |
Method of treating abnormal cell growth
|
|
GB201016442D0
(en)
|
2010-09-30 |
2010-11-17 |
Pharminox Ltd |
Novel acridine derivatives
|
|
EP2630134B9
(en)
|
2010-10-20 |
2018-04-18 |
Pfizer Inc |
Pyridine-2- derivatives as smoothened receptor modulators
|
|
DE102010048800A1
(de)
|
2010-10-20 |
2012-05-10 |
Merck Patent Gmbh |
Chinoxalinderivate
|
|
DE102010049595A1
(de)
|
2010-10-26 |
2012-04-26 |
Merck Patent Gmbh |
Chinazolinderivate
|
|
WO2012066335A1
(en)
|
2010-11-19 |
2012-05-24 |
Astrazeneca Ab |
Phenol compounds als toll -like receptor 7 agonists
|
|
JP2013542916A
(ja)
|
2010-11-19 |
2013-11-28 |
大日本住友製薬株式会社 |
環状アミド化合物および疾患の処置におけるその使用
|
|
WO2012066336A1
(en)
|
2010-11-19 |
2012-05-24 |
Astrazeneca Ab |
Benzylamine compounds as toll -like receptor 7 agonists
|
|
WO2012067269A1
(en)
|
2010-11-19 |
2012-05-24 |
Dainippon Sumitomo Pharma Co., Ltd. |
Aminoalkoxyphenyl compounds and their use in the treatment of disease
|
|
EP2651937B8
(en)
|
2010-12-16 |
2016-07-13 |
Sumitomo Dainippon Pharma Co., Ltd. |
Imidazo[4,5-c]quinolin-1-yl derivative useful in therapy
|
|
WO2012080730A1
(en)
|
2010-12-17 |
2012-06-21 |
Astrazeneca Ab |
Purine derivatives
|
|
KR20140003467A
(ko)
|
2010-12-20 |
2014-01-09 |
메디뮨 리미티드 |
항il-18 항체 및 그의 용도
|
|
US9493503B2
(en)
|
2011-02-02 |
2016-11-15 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
|
TWI617555B
(zh)
|
2011-02-15 |
2018-03-11 |
免疫原公司 |
細胞毒性苯并二氮呯衍生物
|
|
EP2675793B1
(en)
|
2011-02-17 |
2018-08-08 |
Cancer Therapeutics Crc Pty Limited |
Fak inhibitors
|
|
US9174946B2
(en)
|
2011-02-17 |
2015-11-03 |
Cancer Therapeutics Crc Pty Ltd |
Selective FAK inhibitors
|
|
WO2012116040A1
(en)
|
2011-02-22 |
2012-08-30 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma
|
|
GB201104267D0
(en)
|
2011-03-14 |
2011-04-27 |
Cancer Rec Tech Ltd |
Pyrrolopyridineamino derivatives
|
|
WO2012142164A1
(en)
|
2011-04-12 |
2012-10-18 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
|
|
UY34013A
(es)
|
2011-04-13 |
2012-11-30 |
Astrazeneca Ab |
?compuestos de cromenona con actividad anti-tumoral?.
|
|
WO2012145183A2
(en)
|
2011-04-19 |
2012-10-26 |
Pfizer Inc. |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
US9896730B2
(en)
|
2011-04-25 |
2018-02-20 |
OSI Pharmaceuticals, LLC |
Use of EMT gene signatures in cancer drug discovery, diagnostics, and treatment
|
|
WO2012175991A1
(en)
|
2011-06-24 |
2012-12-27 |
Pharminox Limited |
Fused pentacyclic anti - proliferative compounds
|
|
US20140227293A1
(en)
|
2011-06-30 |
2014-08-14 |
Trustees Of Boston University |
Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
|
|
ES2861927T3
(es)
|
2011-07-12 |
2021-10-06 |
Astrazeneca Ab |
N-(6-((2R,3S)-3,4-Dihidroxibutan-2-iloxi)-2-(4-fluorobenciltio)pirimidin-4-il)-3-metilacetidina-1-sulfonamida como modulador del receptor de quimiocina
|
|
EP3409278B8
(en)
|
2011-07-21 |
2020-11-04 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Heterocyclic protein kinase inhibitors
|
|
ES2791308T3
(es)
|
2011-07-27 |
2020-11-03 |
Astrazeneca Ab |
Derivados de 2-(2,4,5-anilino sustituido)pirimidina como moduladores de EGFR útiles para tratar el cáncer
|
|
DE102011111400A1
(de)
|
2011-08-23 |
2013-02-28 |
Merck Patent Gmbh |
Bicyclische heteroaromatische Verbindungen
|
|
CA2846574C
(en)
|
2011-08-26 |
2020-07-07 |
Neupharma, Inc. |
Quinoxaline sulfonamide derivates for use as kinase inhibitors
|
|
WO2013033250A1
(en)
|
2011-09-01 |
2013-03-07 |
Xiangping Qian |
Certain chemical entities, compositions, and methods
|
|
US9518029B2
(en)
|
2011-09-14 |
2016-12-13 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
|
WO2013043935A1
(en)
|
2011-09-21 |
2013-03-28 |
Neupharma, Inc. |
Certain chemical entites, compositions, and methods
|
|
WO2013042006A1
(en)
|
2011-09-22 |
2013-03-28 |
Pfizer Inc. |
Pyrrolopyrimidine and purine derivatives
|
|
WO2013045955A1
(en)
|
2011-09-29 |
2013-04-04 |
The University Of Liverpool |
Prevention and/or treatment of cancer and/or cancer metastasis
|
|
US9249111B2
(en)
|
2011-09-30 |
2016-02-02 |
Neupharma, Inc. |
Substituted quinoxalines as B-RAF kinase inhibitors
|
|
US9783613B2
(en)
|
2011-10-04 |
2017-10-10 |
Igem Therapeutics Limited |
IgE anti-HMW-MAA antibody
|
|
WO2013068902A1
(en)
|
2011-11-08 |
2013-05-16 |
Pfizer Inc. |
Methods of treating inflammatory disorders using anti-m-csf antibodies
|
|
US20130178520A1
(en)
|
2011-12-23 |
2013-07-11 |
Duke University |
Methods of treatment using arylcyclopropylamine compounds
|
|
WO2013112950A2
(en)
|
2012-01-25 |
2013-08-01 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
|
CA2862694C
(en)
|
2012-01-28 |
2020-07-28 |
Merck Patent Gmbh |
Triazolo[4,5-d]pyrimidine derivatives
|
|
PL2812337T3
(pl)
|
2012-02-09 |
2017-01-31 |
Merck Patent Gmbh |
Pochodne furo[3,2-b]pirydynowe jako inhibitory tbk1 oraz ikk
|
|
MX349736B
(es)
|
2012-02-09 |
2017-08-10 |
Merck Patent Gmbh |
Derivados de tetrahidro-quinazolinona como inhibidores de tankirasas y poli(adp-ribosa) polimerasa.
|
|
ES2606638T3
(es)
|
2012-02-21 |
2017-03-24 |
Merck Patent Gmbh |
Derivados de furopiridina
|
|
ES2552518T3
(es)
|
2012-02-21 |
2015-11-30 |
Merck Patent Gmbh |
Derivados cíclicos de diaminopiridina como inhibidores de Syk
|
|
EP2817310B1
(en)
|
2012-02-21 |
2018-03-21 |
Merck Patent GmbH |
8-substituted 2-amino-[1,2,4]triazolo[1,5-a]pyrazines as syk tryrosine kinase inhibitors and gcn2 serin kinase inhibitors
|
|
HK1203948A1
(en)
|
2012-03-07 |
2015-11-06 |
Merck Patent Gmbh |
Triazolopyrazine derivatives
|
|
PL2831077T3
(pl)
|
2012-03-28 |
2016-10-31 |
|
Bicykliczne pochodne pirazynonowe
|
|
WO2013144532A1
(en)
|
2012-03-30 |
2013-10-03 |
Astrazeneca Ab |
3 -cyano- 5 -arylamino-7 -cycloalkylaminopyrrolo [1, 5 -a] pyrimidine derivatives and their use as antitumor agents
|
|
CA2868404A1
(en)
|
2012-04-05 |
2013-10-10 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies against human tweak and human il17 and uses thereof
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
WO2013165924A1
(en)
|
2012-04-29 |
2013-11-07 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
|
RS55062B1
(sr)
|
2012-05-04 |
2016-12-30 |
Merck Patent Gmbh |
Pirolotriazinon derivati
|
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
|
GB201211021D0
(en)
|
2012-06-21 |
2012-08-01 |
Cancer Rec Tech Ltd |
Pharmaceutically active compounds
|
|
US9732161B2
(en)
|
2012-06-26 |
2017-08-15 |
Sutro Biopharma, Inc. |
Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use
|
|
CN104507957B
(zh)
|
2012-07-24 |
2018-12-25 |
默克专利股份有限公司 |
用于治疗关节病的羟基他汀衍生物
|
|
AU2013301865B2
(en)
|
2012-08-07 |
2017-08-17 |
Merck Patent Gmbh |
Pyridopyrimidine derivatives as protein kinase inhibitors
|
|
DK2882714T3
(da)
|
2012-08-08 |
2020-01-20 |
Merck Patent Gmbh |
(aza-)isoquinolinonderivater
|
|
US20160009686A1
(en)
|
2012-08-17 |
2016-01-14 |
Cancer Therapeutics Crc Pty Limited |
Vegfr3 inhibitors
|
|
HK1211208A1
(zh)
|
2012-08-22 |
2016-05-20 |
Immunogen, Inc. |
細胞毒性苯並二氮呯衍生物
|
|
EP2890402B1
(en)
|
2012-08-31 |
2019-04-17 |
Sutro Biopharma, Inc. |
Modified amino acids comprising an azido group
|
|
WO2014041349A1
(en)
|
2012-09-12 |
2014-03-20 |
Cancer Therapeutics Crc Pty Ltd |
Tetrahydropyran-4-ylethylamino- or tetrahydropyranyl-4-ethyloxy-pyrimidines or -pyridazines as isoprenylcysteincarboxymethyl transferase inhibitors
|
|
CN104812389B
(zh)
|
2012-09-24 |
2020-07-17 |
润新生物公司 |
某些化学实体、组合物及方法
|
|
JP6276769B2
(ja)
|
2012-09-26 |
2018-02-07 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ |
Ｐａｒｐインヒビターとしてのキナゾリノン誘導体
|
|
JP6348115B2
(ja)
|
2012-10-26 |
2018-06-27 |
ザ ユニバーシティー オブ クイーンズランド |
がん療法のためのエンドサイトーシス阻害剤および抗体の使用
|
|
WO2014066955A1
(en)
|
2012-11-05 |
2014-05-08 |
Lindley Robyn Alice |
Methods for determining the cause of somatic mutagenesis
|
|
US9725421B2
(en)
|
2012-11-12 |
2017-08-08 |
Neupharma, Inc. |
Substituted quinoxalines as B-raf kinase inhibitors
|
|
CN104797553B
(zh)
|
2012-11-16 |
2017-07-21 |
默克专利股份公司 |
3‑氨基环戊烷甲酰胺衍生物
|
|
US9260426B2
(en)
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
|
EP3381917B1
(en)
|
2013-01-31 |
2021-09-08 |
Bellus Health Cough Inc. |
Imidazopyridine compounds and uses thereof
|
|
US9663475B2
(en)
|
2013-02-25 |
2017-05-30 |
Merck Patent Gmbh |
2 amino-3,4-dihydrcquinazoline derivatives and the use thereof as cathepsin D inhibitors
|
|
HK1219422A1
(zh)
|
2013-02-28 |
2017-04-07 |
Immunogen, Inc. |
包含细胞结合剂及细胞毒素剂的轭合物
|
|
EP2961435B1
(en)
|
2013-02-28 |
2019-05-01 |
ImmunoGen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
WO2014135245A1
(en)
|
2013-03-05 |
2014-09-12 |
Merck Patent Gmbh |
9-(aryl or heteroaryl)-2-(pyrazolyl, pyrrolidinyl or cyclopentyl)aminopurine derivatives as anticancer agents
|
|
BR112015022993B1
(pt)
|
2013-03-14 |
2021-12-14 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Inibidores de jak2 e alk2, composição farmacêutica compreendendo os referidos inibidores e uso destes
|
|
US9937137B2
(en)
|
2013-03-15 |
2018-04-10 |
Neurocentria, Inc. |
Magnesium compositions and uses thereof for cancers
|
|
WO2014161570A1
(en)
|
2013-04-03 |
2014-10-09 |
Roche Glycart Ag |
Antibodies against human il17 and uses thereof
|
|
US9206188B2
(en)
|
2013-04-18 |
2015-12-08 |
Arrien Pharmaceuticals Llc |
Substituted pyrrolo[2,3-b]pyridines as ITK and JAK inhibitors
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
EP3004073A1
(en)
|
2013-06-07 |
2016-04-13 |
Université catholique de Louvain |
3-carboxy substituted coumarin derivatives with a potential utility for the treatment of cancer diseases
|
|
JP6802063B2
(ja)
|
2013-06-25 |
2020-12-16 |
エピアクシス セラピューティクス プロプライエタリー リミテッド |
癌幹細胞を調節するための方法および組成物
|
|
WO2015006555A2
(en)
|
2013-07-10 |
2015-01-15 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
|
SG10201908045VA
(en)
|
2013-08-23 |
2019-10-30 |
Neupharma Inc |
Certain chemical entities, compositions, and methods
|
|
ES2851724T3
(es)
|
2013-09-18 |
2021-09-08 |
Epiaxis Therapeutics Pty Ltd |
Modulación de células madre
|
|
US20160298197A1
(en)
|
2013-10-01 |
2016-10-13 |
Queensland University Of Technology |
Kits and methods for diagnosis, screening, treatment and disease monitoring
|
|
ES2775579T3
(es)
|
2013-10-04 |
2020-07-27 |
Aptose Biosciences Inc |
Composiciones para el tratamiento del cáncer
|
|
US9840493B2
(en)
|
2013-10-11 |
2017-12-12 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
|
UA115388C2
(uk)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-заміщені пуринові похідні та їх застосування в лікуванні проліферативних захворювань
|
|
GB201321146D0
(en)
*
|
2013-11-29 |
2014-01-15 |
Cancer Rec Tech Ltd |
Quinazoline compounds
|
|
US8986691B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
|
US8980273B1
(en)
|
2014-07-15 |
2015-03-17 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
|
US9242965B2
(en)
|
2013-12-31 |
2016-01-26 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
|
|
CN104829542B
(zh)
*
|
2014-02-10 |
2018-02-02 |
中国科学院上海药物研究所 |
苯胺嘧啶类化合物、其制备方法和医药用途
|
|
GB201403536D0
(en)
|
2014-02-28 |
2014-04-16 |
Cancer Rec Tech Ltd |
Inhibitor compounds
|
|
WO2015149721A1
(en)
|
2014-04-04 |
2015-10-08 |
Crown Bioscience, Inc.(Taicang) |
Methods for determining responsiveness to mek/erk inhibitors
|
|
WO2015155624A1
(en)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dihydropyrrolopyrimidine derivatives
|
|
AU2015254943B2
(en)
|
2014-04-30 |
2019-04-04 |
Pfizer Inc. |
Cycloalkyl-linked diheterocycle derivatives
|
|
WO2016001789A1
(en)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
|
WO2016019280A1
(en)
|
2014-07-31 |
2016-02-04 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Human monoclonal antibodies against epha4 and their use
|
|
CN105330653A
(zh)
*
|
2014-08-11 |
2016-02-17 |
石药集团中奇制药技术（石家庄）有限公司 |
喹唑啉衍生物
|
|
CA2958704A1
(en)
|
2014-08-25 |
2016-03-03 |
University Of Canberra |
Compositions for modulating cancer stem cells and uses therefor
|
|
WO2016077881A1
(en)
|
2014-11-17 |
2016-05-26 |
The University Of Queensland |
Glycoprotein biomarkers for esophageal adenocarcinoma and barrett's esophagus and uses thereof
|
|
ES2746839T3
(es)
|
2014-12-18 |
2020-03-09 |
Pfizer |
Derivados de pirimidina y triazina y su uso como inhibidores de AXL
|
|
MA41179A
(fr)
|
2014-12-19 |
2017-10-24 |
Cancer Research Tech Ltd |
Composés inhibiteurs de parg
|
|
GB201501870D0
(en)
|
2015-02-04 |
2015-03-18 |
Cancer Rec Tech Ltd |
Autotaxin inhibitors
|
|
GB201502020D0
(en)
|
2015-02-06 |
2015-03-25 |
Cancer Rec Tech Ltd |
Autotaxin inhibitory compounds
|
|
EP3270694A4
(en)
|
2015-02-17 |
2018-09-05 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
|
EP3286564A1
(en)
|
2015-04-20 |
2018-02-28 |
Tolero Pharmaceuticals, Inc. |
Predicting response to alvocidib by mitochondrial profiling
|
|
US10011629B2
(en)
|
2015-05-01 |
2018-07-03 |
Cocrystal Pharma, Inc. |
Nucleoside analogs for treatment of the flaviviridae family of viruses and cancer
|
|
PT3298021T
(pt)
|
2015-05-18 |
2019-08-05 |
Tolero Pharmaceuticals Inc |
Pró-fármacos de alvocidib possuindo biodisponibilidade aumentada
|
|
GB201510019D0
(en)
|
2015-06-09 |
2015-07-22 |
Cancer Therapeutics Crc Pty Ltd |
Compounds
|
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
|
MX2018001289A
(es)
|
2015-08-03 |
2018-04-30 |
Tolero Pharmaceuticals Inc |
Terapias de combinacion para el tratamiento del cancer.
|
|
EP3331880B3
(en)
|
2015-08-04 |
2023-01-11 |
Aucentra Therapeutics Pty Ltd |
N-(pyridin-2-yl)-4-(thiazol-5-yl)pyrimidin-2-amine derivatives as therapeutic compounds
|
|
EP3341496B1
(en)
|
2015-08-26 |
2021-02-24 |
GMDx Co Pty Ltd |
Methods of detecting cancer recurrence
|
|
GB201516504D0
(en)
|
2015-09-17 |
2015-11-04 |
Astrazeneca Ab |
Imadazo(4,5-c)quinolin-2-one Compounds and their use in treating cancer
|
|
GB201519568D0
(en)
|
2015-11-05 |
2015-12-23 |
Astrazeneca Ab |
Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
|
|
CA3006743A1
(en)
|
2015-12-03 |
2017-06-08 |
Agios Pharmaceuticals, Inc. |
Mat2a inhibitors for treating mtap null cancer
|
|
EP3393480B1
(en)
|
2015-12-23 |
2025-11-12 |
Repluca Pty Ltd |
Nucleic acid oligomers and uses therefor
|
|
MX2018009085A
(es)
|
2016-01-27 |
2019-05-09 |
Sutro Biopharma Inc |
Conjugados de anticuerpos anti-cd74, composiciones que comprenden conjugados de anticuerpos anti-cd74 y metodos de uso de congujados de anticuerpos anti-cd74.
|
|
US10487115B2
(en)
|
2016-02-01 |
2019-11-26 |
University Of Canberra |
Proteinaceous compounds and uses therefor
|
|
GB201604182D0
(en)
|
2016-03-11 |
2016-04-27 |
Astrazeneca Ab |
Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
|
|
CA3017035A1
(en)
|
2016-03-21 |
2017-09-28 |
Astrazeneca Ab |
Cinnolin-4-amine compounds and their use in treating cancer
|
|
JP2019513730A
(ja)
|
2016-04-07 |
2019-05-30 |
アストラゼネカ・アクチエボラーグＡｓｔｒａｚｅｎｅｃａ Ａｋｔｉｅｂｏｌａｇ |
癌を治療するためのＡＴＭ（毛細血管拡張性運動失調症変異）キナーゼモジュレータとしてのＮ，Ｎ−ジメチル−３−［［５−（３−メチル−２−オキソ−１−テトラヒドロピラン−４−イル−イミダゾ［４，５−ｃ］キノリン−８−イル）−２−ピリジル］オキシ］プロパン−１−アミンオキシド
|
|
SMT202200348T1
(it)
|
2016-04-15 |
2022-11-18 |
Cancer Research Tech Ltd |
Composti eterociclici come inibitori della chinasi ret
|
|
GB2554333A
(en)
|
2016-04-26 |
2018-04-04 |
Big Dna Ltd |
Combination therapy
|
|
GB201608227D0
(en)
|
2016-05-11 |
2016-06-22 |
Astrazeneca Ab |
Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
|
|
TWI817929B
(zh)
|
2016-07-29 |
2023-10-11 |
美商瑞佩特治療公司 |
趨化介素受體調節劑及其用途
|
|
CN109843858B
(zh)
|
2016-08-15 |
2023-05-05 |
润新生物公司 |
某些化学实体、组合物及方法
|
|
AU2017321973B2
(en)
|
2016-09-02 |
2024-09-05 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of treating B cell disorders
|
|
EP3515903B1
(en)
|
2016-09-22 |
2020-10-21 |
Cancer Research Technology Limited |
Preparation and uses of pyrimidinone derivatives
|
|
GB201617103D0
(en)
|
2016-10-07 |
2016-11-23 |
Cancer Research Technology Limited |
Compound
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
US10786502B2
(en)
|
2016-12-05 |
2020-09-29 |
Apros Therapeutics, Inc. |
Substituted pyrimidines containing acidic groups as TLR7 modulators
|
|
ES2906439T3
(es)
|
2016-12-05 |
2022-04-18 |
Apros Therapeutics Inc |
Compuestos de pirimidina que contienen grupos ácidos
|
|
EP3362471B1
(en)
|
2016-12-19 |
2021-11-17 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Profiling peptides and methods for sensitivity profiling
|
|
MA47079B1
(fr)
|
2016-12-20 |
2021-05-31 |
Astrazeneca Ab |
Composés amino-triazolopyidines et leur utilisation pour traiter le cancer
|
|
SG11201907095UA
(en)
|
2017-02-01 |
2019-08-27 |
Aucentra Therapeutics Pty Ltd |
DERIVATIVES OF N-CYCLOALKYL/HETEROCYCLOALKYL-4-(IMIDAZO [1,2-a]PYRIDINE)PYRIMIDIN-2-AMINE AS THERAPEUTIC AGENTS
|
|
US10703723B2
(en)
|
2017-03-09 |
2020-07-07 |
Truly Translational Sweden Ab |
Prodrugs of sulfasalazine, pharmaceutical compositions thereof and their use in the treatment of autoimmune disease
|
|
JOP20190209A1
(ar)
|
2017-03-16 |
2019-09-12 |
Astrazeneca Ab |
مركبات إيميدازو [ 4، 5-c ] كينولين-2-أون ديوترومية واستخدامها في علاج السرطان
|
|
GB201704325D0
(en)
|
2017-03-17 |
2017-05-03 |
Argonaut Therapeutics Ltd |
Compounds
|
|
GB201705971D0
(en)
|
2017-04-13 |
2017-05-31 |
Cancer Res Tech Ltd |
Inhibitor compounds
|
|
CN108864079B
(zh)
|
2017-05-15 |
2021-04-09 |
深圳福沃药业有限公司 |
一种三嗪化合物及其药学上可接受的盐
|
|
EP3630749B9
(en)
|
2017-05-26 |
2024-05-29 |
Cancer Research Technology Limited |
2-quinolone derived inhibitors of bcl6
|
|
KR102628675B1
(ko)
|
2017-05-26 |
2024-01-25 |
캔써 리서치 테크놀로지 리미티드 |
벤즈이미다졸론 유래된 bcl6의 저해제
|
|
US11883405B2
(en)
|
2017-05-31 |
2024-01-30 |
Amplio Pharma Ab |
Pharmaceutical composition comprising a combination of methotrexate and novobiocin, and the use of said composition in therapy
|
|
US11319304B2
(en)
*
|
2017-06-28 |
2022-05-03 |
Vanderbilt University |
Pyridine quinoline compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
|
|
EP3648797A1
(en)
|
2017-07-05 |
2020-05-13 |
EPOS-Iasis Research and Development, Ltd |
Multifunctional conjugates
|
|
WO2019023316A1
(en)
|
2017-07-26 |
2019-01-31 |
Sutro Biopharma, Inc. |
METHODS OF USING ANTI-CD74 ANTIBODIES AND ANTIBODY CONJUGATES IN THE TREATMENT OF A T CELL LYMPHOMA
|
|
ES2940407T3
(es)
|
2017-08-01 |
2023-05-08 |
Merck Patent Gmbh |
Derivados de tiazolopiridina como antagonistas de los receptores de adenosina
|
|
US11447505B1
(en)
|
2017-08-18 |
2022-09-20 |
Cancer Research Technology Limited |
Pyrrolo[2,3-b]pyridine compounds and their use in the treatment of cancer
|
|
SG11202001337XA
(en)
|
2017-08-21 |
2020-03-30 |
Merck Patent Gmbh |
Bezimidazole derivatives as adenosine receptor antagonists
|
|
TW201920123A
(zh)
|
2017-08-21 |
2019-06-01 |
德商馬克專利公司 |
作為腺苷受體拮抗劑之喹㗁啉衍生物
|
|
JP7196160B2
(ja)
|
2017-09-12 |
2022-12-26 |
スミトモ ファーマ オンコロジー， インコーポレイテッド |
Ｍｃｌ－１阻害剤アルボシジブを用いた、ｂｃｌ－２阻害剤に対して非感受性である癌の治療レジメン
|
|
CN111655726B
(zh)
|
2017-09-18 |
2024-06-21 |
苏特罗生物制药公司 |
抗叶酸受体α抗体偶联物和其用途
|
|
WO2019057757A1
(en)
|
2017-09-20 |
2019-03-28 |
Astrazeneca Ab |
1,3-DIHYDROIMIDAZO [4,5-C] CINNOLIN-2-ONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER
|
|
TWI702205B
(zh)
|
2017-10-06 |
2020-08-21 |
俄羅斯聯邦商拜奧卡德聯合股份公司 |
表皮生長因子受體抑制劑
|
|
WO2019075367A1
(en)
|
2017-10-13 |
2019-04-18 |
Tolero Pharmaceuticals, Inc. |
PKM2 ACTIVATORS IN COMBINATION WITH OXYGEN REACTIVE SPECIES FOR THE TREATMENT OF CANCER
|
|
SG11202004105TA
(en)
|
2017-11-06 |
2020-06-29 |
Rapt Therapeutics Inc |
Anticancer agents
|
|
EP3488868B1
(en)
|
2017-11-23 |
2023-09-13 |
medac Gesellschaft für klinische Spezialpräparate mbH |
Pharmaceutical composition for oral administration containing sulfasalazine and / or a sulfasalazine organic salt, production process and use
|
|
EP3489222A1
(en)
|
2017-11-23 |
2019-05-29 |
medac Gesellschaft für klinische Spezialpräparate mbH |
Sulfasalazine salts, production processes and uses
|
|
EP3740484B1
(en)
|
2018-01-15 |
2024-09-11 |
Aucentra Therapeutics Pty Ltd |
5-(pyrimidin-4-yl)thiazol-2-yl urea derivatives as therapeutic agents
|
|
GB201801128D0
(en)
|
2018-01-24 |
2018-03-07 |
Univ Oxford Innovation Ltd |
Compounds
|
|
KR102860287B1
(ko)
|
2018-01-26 |
2025-09-16 |
랩트 테라퓨틱스, 인크. |
케모카인 수용체 조정제 및 그의 용도
|
|
CN112105365A
(zh)
|
2018-02-08 |
2020-12-18 |
润新生物公司 |
某些化学实体、组合物和方法
|
|
WO2019175093A1
(en)
|
2018-03-12 |
2019-09-19 |
Astrazeneca Ab |
Method for treating lung cancer
|
|
CN119330979A
(zh)
|
2018-04-13 |
2025-01-21 |
癌症研究技术有限公司 |
作为bcl6抑制剂的化合物及其制备方法
|
|
ES2991516T3
(es)
|
2018-04-27 |
2024-12-03 |
Spruce Biosciences Inc |
Métodos para tratar tumores de restos adrenales testiculares y ováricos
|
|
US10857153B2
(en)
|
2018-06-04 |
2020-12-08 |
Apros Therapeutics, Inc. |
Pyrimidine compounds containing acidic groups
|
|
GB201809102D0
(en)
|
2018-06-04 |
2018-07-18 |
Univ Oxford Innovation Ltd |
Compounds
|
|
JP2021527051A
(ja)
|
2018-06-05 |
2021-10-11 |
ラプト・セラピューティクス・インコーポレイテッド |
ピラゾロ−ピリミジン−アミノ−シクロアルキル化合物及びその治療的使用
|
|
GB201810092D0
(en)
|
2018-06-20 |
2018-08-08 |
Ctxt Pty Ltd |
Compounds
|
|
GB201810581D0
(en)
|
2018-06-28 |
2018-08-15 |
Ctxt Pty Ltd |
Compounds
|
|
US11040038B2
(en)
|
2018-07-26 |
2021-06-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Methods for treating diseases associated with abnormal ACVR1 expression and ACVR1 inhibitors for use in the same
|
|
CN115636833B
(zh)
|
2018-09-14 |
2024-11-29 |
苏州赞荣医药科技有限公司 |
作为ATM激酶选择性调节剂的取代的咪唑并[4,5-c]噌啉-2-酮化合物及其用途
|
|
WO2020060944A1
(en)
|
2018-09-17 |
2020-03-26 |
Sutro Biopharma, Inc. |
Combination therapies with anti-folate receptor antibody conjugates
|
|
KR20250171398A
(ko)
|
2018-09-18 |
2025-12-08 |
에프. 호프만-라 로체 에이지 |
항종양제로서의 퀴나졸린 유도체
|
|
WO2020068600A1
(en)
|
2018-09-24 |
2020-04-02 |
Rapt Therapeutics, Inc. |
Ubiquitin-specific-processing protease 7 (usp7) modulators and uses thereof
|
|
BR112021007727A2
(pt)
|
2018-10-25 |
2021-07-27 |
Merck Patent Gmbh |
derivados de 5-azaindazol como antagonistas receptores de adenosina
|
|
IL282526B2
(en)
|
2018-10-25 |
2025-03-01 |
Merck Patent Gmbh |
History and Use of 5-Azaindazole
|
|
GB201819126D0
(en)
|
2018-11-23 |
2019-01-09 |
Cancer Research Tech Ltd |
Inhibitor compounds
|
|
KR20210099066A
(ko)
|
2018-12-04 |
2021-08-11 |
스미토모 다이니폰 파마 온콜로지, 인크. |
암의 치료를 위한 작용제로서 사용하기 위한 cdk9 억제제 및 그의 다형체
|
|
CA3124730A1
(en)
|
2018-12-25 |
2020-07-02 |
Institute Of Basic Medical Sciences Chinese Academy Of Medical Sciences |
Small rna medicament for prevention and treatment of inflammation-related diseases and combinations thereof
|
|
AR117844A1
(es)
|
2019-01-22 |
2021-09-01 |
Merck Patent Gmbh |
Derivados de tiazolopiridina como antagonistas del receptor de adenosina
|
|
WO2020167990A1
(en)
|
2019-02-12 |
2020-08-20 |
Tolero Pharmaceuticals, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
|
CN113727716A
(zh)
|
2019-02-25 |
2021-11-30 |
贝卢斯医疗咳嗽病公司 |
采用p2x3调节剂的治疗
|
|
CA3127361A1
(en)
|
2019-03-07 |
2020-09-10 |
Merck Patent Gmbh |
Carboxamide-pyrimidine derivatives as shp2 antagonists
|
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
|
KR20210141621A
(ko)
|
2019-03-22 |
2021-11-23 |
스미토모 다이니폰 파마 온콜로지, 인크. |
Pkm2 조정제를 포함하는 조성물 및 그를 사용한 치료 방법
|
|
CN120737069A
(zh)
|
2019-03-28 |
2025-10-03 |
安普利亚治疗有限公司 |
Fak抑制剂的盐和晶型
|
|
KR20210144844A
(ko)
|
2019-03-29 |
2021-11-30 |
아스트라제네카 아베 |
비-소세포 폐암의 치료에 사용하기 위한 오시머티닙
|
|
CN111747931A
(zh)
|
2019-03-29 |
2020-10-09 |
深圳福沃药业有限公司 |
用于治疗癌症的氮杂芳环酰胺衍生物
|
|
EP3946618A1
(en)
|
2019-04-05 |
2022-02-09 |
Storm Therapeutics Ltd |
Mettl3 inhibitory compounds
|
|
CN113646049B
(zh)
|
2019-04-08 |
2024-08-13 |
默克专利有限公司 |
作为shp2拮抗剂的嘧啶酮衍生物
|
|
GB201905328D0
(en)
|
2019-04-15 |
2019-05-29 |
Azeria Therapeutics Ltd |
Inhibitor compounds
|
|
WO2020227105A1
(en)
|
2019-05-03 |
2020-11-12 |
Sutro Biopharma, Inc. |
Anti-bcma antibody conjugates
|
|
GB201908885D0
(en)
|
2019-06-20 |
2019-08-07 |
Storm Therapeutics Ltd |
Therapeutic compounds
|
|
CN114728910B
(zh)
|
2019-08-31 |
2024-05-14 |
上海奕拓医药科技有限责任公司 |
用于fgfr抑制剂的吡唑类衍生物及其制备方法
|
|
CA3147493A1
(en)
|
2019-09-20 |
2021-03-25 |
Jr. James Clifford Sutton |
4-substituted indole and indazole sulfonamido derivatives as parg inhibitors
|
|
GB201913988D0
(en)
|
2019-09-27 |
2019-11-13 |
Celleron Therapeutics Ltd |
Novel treatment
|
|
GB201914860D0
(en)
|
2019-10-14 |
2019-11-27 |
Cancer Research Tech Ltd |
Inhibitor compounds
|
|
GB201915829D0
(en)
|
2019-10-31 |
2019-12-18 |
Cancer Research Tech Ltd |
Compounds, compositions and therapeutic uses thereof
|
|
GB201915831D0
(en)
|
2019-10-31 |
2019-12-18 |
Cancer Research Tech Ltd |
Compounds, compositions and therapeutic uses thereof
|
|
GB201915828D0
(en)
|
2019-10-31 |
2019-12-18 |
Cancer Research Tech Ltd |
Compounds, compositions and therapeutic uses thereof
|
|
KR20220113431A
(ko)
|
2019-12-02 |
2022-08-12 |
스톰 테라퓨틱스 리미티드 |
Mettl3 저해제로서의 폴리헤테로환식 화합물
|
|
WO2021155006A1
(en)
|
2020-01-31 |
2021-08-05 |
Les Laboratoires Servier Sas |
Inhibitors of cyclin-dependent kinases and uses thereof
|
|
US20230095053A1
(en)
|
2020-03-03 |
2023-03-30 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
|
GB202004960D0
(en)
|
2020-04-03 |
2020-05-20 |
Kinsenus Ltd |
Inhibitor compounds
|
|
GB202012969D0
(en)
|
2020-08-19 |
2020-09-30 |
Univ Of Oxford |
Inhibitor compounds
|
|
WO2022074379A1
(en)
|
2020-10-06 |
2022-04-14 |
Storm Therapeutics Limited |
Mettl3 inhibitory compounds
|
|
US20240101589A1
(en)
|
2020-10-08 |
2024-03-28 |
Strom Therapeutics Limited |
Inhibitors of mettl3
|
|
EP3992191A1
(en)
|
2020-11-03 |
2022-05-04 |
Deutsches Krebsforschungszentrum |
Imidazo[4,5-c]quinoline compounds and their use as atm kinase inhibitors
|
|
GB202102895D0
(en)
|
2021-03-01 |
2021-04-14 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
|
WO2022197641A1
(en)
|
2021-03-15 |
2022-09-22 |
Rapt Therapeutics, Inc. |
1h-pyrazolo[3,4-d]pyrimidin-6-yl-amine derivatives as hematopoietic progenitor kinase 1 (hpk1) modulators and/or inhibitors for the treatment of cancer and other diseases
|
|
TW202308702A
(zh)
|
2021-04-30 |
2023-03-01 |
美商西建公司 |
使用抗BCMA抗體藥物結合物(ADC)組合γ分泌酶抑制劑(GSI)之組合療法
|
|
EP4333900A2
(en)
|
2021-05-03 |
2024-03-13 |
Merck Patent GmbH |
Her2 targeting fc antigen binding fragment-drug conjugates
|
|
MX2023013690A
(es)
|
2021-05-17 |
2024-01-30 |
Hk Inno N Corp |
Derivado de benzamida, metodo para preparar el mismo, y composicion farmaceutica para la prevencion o tratamiento del cancer que contiene el mismo como ingrediente activo.
|
|
EP4346905A1
(en)
|
2021-05-25 |
2024-04-10 |
Merck Patent GmbH |
Egfr targeting fc antigen binding fragment-drug conjugates
|
|
GB202107907D0
(en)
|
2021-06-02 |
2021-07-14 |
Storm Therapeutics Ltd |
Combination therapies
|
|
GB202108383D0
(en)
|
2021-06-11 |
2021-07-28 |
Argonaut Therapeutics Ltd |
Compounds useful in the treatment or prevention of a prmt5-mediated disorder
|
|
AU2022359801A1
(en)
|
2021-10-04 |
2024-02-01 |
Forx Therapeutics Ag |
Parg inhibitory compounds
|
|
EP4413000A1
(en)
|
2021-10-04 |
2024-08-14 |
FoRx Therapeutics AG |
N,n-dimethyl-4-(7-(n-(1-methylcyclopropyl)sulfamoyl)-imidazo[1,5-a]pyridin-5-yl)piperazine-1-carboxamide derivatives and the corresponding pyrazolo[1,5-a]pyridine derivatives as parg inhibitors for the treatment of cancer
|
|
PE20242106A1
(es)
|
2021-10-20 |
2024-10-28 |
Hoffmann La Roche |
Formas cristalinas de derivados de quinazolina, preparacion, composicion y uso de estas
|
|
US20250084074A1
(en)
|
2022-01-10 |
2025-03-13 |
Merck Patent Gmbh |
Substituted heterocycles as hset inhibitors
|
|
GB202202199D0
(en)
|
2022-02-18 |
2022-04-06 |
Cancer Research Tech Ltd |
Compounds
|
|
WO2023175185A1
(en)
|
2022-03-17 |
2023-09-21 |
Forx Therapeutics Ag |
2,4-dioxo-1,4-dihydroquinazoline derivatives as parg inhibitors for the treatment of cancer
|
|
WO2023175184A1
(en)
|
2022-03-17 |
2023-09-21 |
Forx Therapeutics Ag |
2,4-dioxo-1,4-dihydroquinazoline derivatives as parg inhibitors for the treatment of cancer
|
|
WO2023186881A1
(en)
|
2022-03-29 |
2023-10-05 |
Baden-Württemberg Stiftung Ggmbh |
P38 map kinase inhibitors for use in the treatment of colorectal cancer
|
|
GB202204935D0
(en)
|
2022-04-04 |
2022-05-18 |
Cambridge Entpr Ltd |
Nanoparticles
|
|
EP4504338A1
(en)
|
2022-04-06 |
2025-02-12 |
RAPT Therapeutics, Inc. |
Chemokine receptor modulators and uses thereof
|
|
GB202209404D0
(en)
|
2022-06-27 |
2022-08-10 |
Univ Of Sussex |
Compounds
|
|
IL317782A
(en)
|
2022-06-30 |
2025-02-01 |
Sutro Biopharma Inc |
Anti-ROR1 antibodies and conjugates thereof, compositions containing anti-ROR1 antibodies or conjugates thereof, and methods for preparing and using anti-ROR1 antibodies and conjugates thereof
|
|
WO2024030825A1
(en)
|
2022-08-01 |
2024-02-08 |
Neupharma, Inc |
Crystalline salts of crystalline salts of (3s,5r,8r,9s,10s,13r,14s,17r)-14-hydroxy-10,13-dimethyl-17-(2- oxo-2h-pyran-5-yl)hexadecahydro-1h-cyclopenta[a]phenanthren-3-yl piperazine-1-carboxylate
|
|
GB202213163D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
|
GB202213167D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
|
GB202213164D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
|
GB202213162D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Prodrugs
|
|
GB202213166D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
|
WO2024074497A1
(en)
|
2022-10-03 |
2024-04-11 |
Forx Therapeutics Ag |
Parg inhibitory compound
|
|
WO2024094963A1
(en)
|
2022-11-02 |
2024-05-10 |
Cancer Research Technology Limited |
2-amino-pyrido[2,3-d]pyrimidin-7(8h)-one and 7-amino-1-pyrimido[4,5-d]pyrimidin-2(1 h)-one derivatives as egfr inhibitors for the treatment of cancer
|
|
WO2024094962A1
(en)
|
2022-11-02 |
2024-05-10 |
Cancer Research Technology Limited |
Pyrido[2,3-d]pyrimidin-2-amine derivatives as egfr inhibitors for the treatment of cancer
|
|
AR130957A1
(es)
|
2022-11-07 |
2025-02-05 |
Merck Patent Gmbh |
Inhibidores de hset bicíclicos y tricíclicos sustituidos
|
|
GB202218672D0
(en)
|
2022-12-12 |
2023-01-25 |
Storm Therapeutics Ltd |
Inhibitory compounds
|
|
EP4423089A4
(en)
|
2023-01-18 |
2025-01-08 |
Antengene Discovery Limited |
PRMT5 INHIBITOR COMPOUNDS AND THEIR USES
|
|
WO2024173453A1
(en)
|
2023-02-14 |
2024-08-22 |
Ideaya Biosciences, Inc. |
Heteroaryl-substituted imidazopyridine compounds
|
|
WO2024173524A1
(en)
|
2023-02-14 |
2024-08-22 |
Ideaya Biosciences, Inc. |
Heteroaryl-substituted benzimidazole compounds
|
|
WO2024173530A1
(en)
|
2023-02-14 |
2024-08-22 |
Ideaya Biosciences, Inc. |
Heteroaryl-substituted pyrazolo/imidazo pyridine compounds
|
|
WO2024173514A1
(en)
|
2023-02-14 |
2024-08-22 |
Ideaya Biosciences, Inc. |
Amide and ester-substituted imidazopyridine compounds
|
|
US12162895B2
(en)
|
2023-03-10 |
2024-12-10 |
Breakpoint Therapeutics Gmbh |
DNA polymerase theta inhibitor for treatment of cancer
|
|
EP4434972A1
(en)
|
2023-03-22 |
2024-09-25 |
Eberhard-Karls-Universität Tübingen |
Atm kinase inhibitors
|
|
WO2024209035A1
(en)
|
2023-04-05 |
2024-10-10 |
Forx Therapeutics Ag |
Parg inhibitory compounds
|
|
GB2631507A
(en)
|
2023-07-04 |
2025-01-08 |
Univ Liverpool |
Compositions
|
|
GB2631509A
(en)
|
2023-07-04 |
2025-01-08 |
Univ Liverpool |
Compositions
|
|
WO2025043017A1
(en)
*
|
2023-08-21 |
2025-02-27 |
University Of Central Florida Research Foundation, Inc. |
Efficient identification of new small molecules targeting succinate dehydrogenase
|
|
WO2025046148A1
(en)
|
2023-09-01 |
2025-03-06 |
Forx Therapeutics Ag |
Novel parg inhibitors
|
|
WO2025056923A1
(en)
|
2023-09-15 |
2025-03-20 |
Cambridge Enterprise Limited |
Combination therapy
|
|
WO2025073792A1
(en)
|
2023-10-02 |
2025-04-10 |
Forx Therapeutics Ag |
Wrn inhibitory compounds
|
|
GB202315149D0
(en)
|
2023-10-03 |
2023-11-15 |
Celleron Therapeutics Ltd |
Combination therapy
|
|
WO2025073870A1
(en)
|
2023-10-03 |
2025-04-10 |
Forx Therapeutics Ag |
Parg inhibitory compound
|
|
WO2025081117A2
(en)
|
2023-10-13 |
2025-04-17 |
Sutro Biopharma, Inc. |
Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates
|
|
GB202316595D0
(en)
|
2023-10-30 |
2023-12-13 |
Storm Therapeutics Ltd |
Inhibitory compounds
|
|
GB202316683D0
(en)
|
2023-10-31 |
2023-12-13 |
Storm Therapeutics Ltd |
Inhibitory compounds
|
|
WO2025093755A1
(en)
|
2023-11-01 |
2025-05-08 |
Forx Therapeutics Ag |
Novel parc inhibitors
|
|
GB202317368D0
(en)
|
2023-11-13 |
2023-12-27 |
Breakpoint Therapeutics Gmbh |
Novel compounds, compositions and therapeutic uses thereof
|
|
WO2025104443A1
(en)
|
2023-11-14 |
2025-05-22 |
Storm Therapeutics Ltd |
Inhibitory compounds
|
|
WO2025114480A1
(en)
|
2023-11-28 |
2025-06-05 |
Forx Therapeutics Ag |
Wrn inhibitory compounds
|
|
WO2025136811A1
(en)
|
2023-12-18 |
2025-06-26 |
Ideaya Biosciences, Inc. |
Chemical compounds and uses thereof
|
|
GB202319863D0
(en)
|
2023-12-21 |
2024-02-07 |
Breakpoint Therapeutics Gmbh |
Movel compounds, compositions and therapeutics uses thereof
|
|
GB202319864D0
(en)
|
2023-12-21 |
2024-02-07 |
Breakpoint Therapeutics Gmbh |
Novel compounds, compositions and therapeutic uses thereof
|
|
WO2025133396A1
(en)
|
2023-12-22 |
2025-06-26 |
Forx Therapeutics Ag |
Novel bicyclo heteroaryl parg inhibitors
|
|
WO2025133395A1
(en)
|
2023-12-22 |
2025-06-26 |
Forx Therapeutics Ag |
Bicyclic (hetero)arylene wrn inhibitory compounds
|
|
WO2025191176A1
(en)
|
2024-03-14 |
2025-09-18 |
Forx Therapeutics Ag |
Wrn inhibitory compounds
|
|
NL2037411B1
(en)
|
2024-04-08 |
2025-10-31 |
Univ Leiden |
Protac compounds
|
|
WO2025250825A1
(en)
|
2024-05-30 |
2025-12-04 |
Sutro Biopharma, Inc. |
Anti-trop2 antibodies, compositions comprising anti-trop2 antibodies and methods of making and using anti-trop2 antibodies
|
|
GB202407738D0
(en)
|
2024-05-31 |
2024-07-17 |
Storm Therapeutics Ltd |
Inhibitory compounds
|
|
WO2025262192A1
(en)
|
2024-06-21 |
2025-12-26 |
Breakpoint Therapeutics Gmbh |
Quinazoline derivatives suitable for use as werner syndrome helicase protein inhibitors
|
|
WO2026003380A1
(en)
|
2024-06-28 |
2026-01-02 |
Forx Therapeutics Ag |
Wrn inhibitory compounds
|
|
CN119912427A
(zh)
*
|
2025-01-02 |
2025-05-02 |
浙江工业大学 |
2-溴-4-（哌啶基甲基）吡啶的合成方法
|