HU218140B - Humán interleukin-6-receptorral szembeni átalakított humán antitest - Google Patents
Humán interleukin-6-receptorral szembeni átalakított humán antitest Download PDFInfo
- Publication number
- HU218140B HU218140B HU9303002A HU9303002A HU218140B HU 218140 B HU218140 B HU 218140B HU 9303002 A HU9303002 A HU 9303002A HU 9303002 A HU9303002 A HU 9303002A HU 218140 B HU218140 B HU 218140B
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- Hungary
- Prior art keywords
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- gly
- gin
- Prior art date
Links
- 0 C(C1)*1(C1)*2C1C=CCC2 Chemical compound C(C1)*1(C1)*2C1C=CCC2 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3095476A JPH05236966A (ja) | 1991-04-25 | 1991-04-25 | ヒトインターロイキン−6レセプターに対するマウスモノクローナル抗体の可変領域をコードするdna |
| JP4032084A JPH05227970A (ja) | 1992-02-19 | 1992-02-19 | ヒトインターロイキン−6受容体に対する再構成ヒト抗体 |
| PCT/JP1992/000544 WO1992019759A1 (fr) | 1991-04-25 | 1992-04-24 | Anticorps humains reconstitues diriges contre un recepteur de l'interleukine 6 humaine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9303002D0 HU9303002D0 (en) | 1994-01-28 |
| HUT70258A HUT70258A (en) | 1995-09-28 |
| HU218140B true HU218140B (hu) | 2000-06-28 |
Family
ID=26370596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9303002A HU218140B (hu) | 1991-04-25 | 1992-04-24 | Humán interleukin-6-receptorral szembeni átalakított humán antitest |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US5795965A (enExample) |
| EP (1) | EP0628639B1 (enExample) |
| JP (6) | JP3370324B2 (enExample) |
| KR (1) | KR100249937B1 (enExample) |
| AT (1) | ATE181575T1 (enExample) |
| AU (2) | AU668349B2 (enExample) |
| DE (2) | DE69229482T2 (enExample) |
| DK (1) | DK0628639T3 (enExample) |
| ES (1) | ES2134212T3 (enExample) |
| GR (1) | GR3031174T3 (enExample) |
| HU (1) | HU218140B (enExample) |
| LU (1) | LU91556I2 (enExample) |
| NL (1) | NL300383I2 (enExample) |
| RU (1) | RU2139351C1 (enExample) |
| TW (1) | TW205553B (enExample) |
| WO (1) | WO1992019759A1 (enExample) |
Families Citing this family (341)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5472693A (en) * | 1993-02-16 | 1995-12-05 | The Dow Chemical Company | Family of anti-carcinoembryonic antigen chimeric antibodies |
| AU6808194A (en) * | 1993-05-31 | 1994-12-20 | Chugai Seiyaku Kabushiki Kaisha | Reconstructed human antibody against human interleukin-6 |
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| CN1306963C (zh) * | 1994-10-21 | 2007-03-28 | 岸本忠三 | 用于治疗il-6产生所致疾病的药物组合物 |
| EP0811384B1 (en) * | 1995-02-13 | 2006-06-21 | Chugai Seiyaku Kabushiki Kaisha | Muscle protein decomposition inhibitor containing il-6 receptor antibody |
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| US20020187150A1 (en) * | 1997-08-15 | 2002-12-12 | Chugai Seiyaku Kabushiki Kaisha | Preventive and/or therapeutic agent for systemic lupus erythematosus comprising anti-IL-6 receptor antibody as an active ingredient |
| PT1004315E (pt) | 1997-08-15 | 2008-07-09 | Chugai Pharmaceutical Co Ltd | Profilácticos e/ou medicamentos contendo anticorpos neutralizantes anti-receptor de il-6 para reduzir a excreção de proteínas urinárias no lúpus eritematoso sistémico |
| CN100374159C (zh) | 1998-03-17 | 2008-03-12 | 中外制药株式会社 | 一种包含il-6拮抗剂活性成分的炎性肠道疾病的预防或治疗剂 |
| DK1069185T3 (da) | 1998-04-03 | 2011-06-27 | Chugai Pharmaceutical Co Ltd | Humaniseret antistof mod human vævsfaktor (TF) og fremgangsmåde til at konstruere humaniseret antistof |
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| ATE481487T1 (de) | 1998-11-27 | 2010-10-15 | Ucb Sa | Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung |
| US7696325B2 (en) | 1999-03-10 | 2010-04-13 | Chugai Seiyaku Kabushiki Kaisha | Polypeptide inducing apoptosis |
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| DK1222854T3 (da) | 1999-10-01 | 2011-03-14 | Chugai Pharmaceutical Co Ltd | Forebyggelse og behandling af sygdomme forbundet med blodkoagulering |
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| WO2002032374A2 (en) * | 2000-10-18 | 2002-04-25 | Immunex Corporation | Methods for treating il-18 mediated disorders |
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| CN1259973C (zh) | 2000-10-25 | 2006-06-21 | 中外制药株式会社 | 含有il-6拮抗剂作为有效成分的牛皮癣的预防或治疗剂 |
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Free format text: PRODUCT NAME: TOCILIZUMAB, RECONSTITUTED HUMAN ANTIBODY AGAINST IL-6R; REG. NO/DATE: EU/1/08/492/001-006 20090116; FIRST REG.: CH 58868/01-03 20081202 Spc suppl protection certif: S0900005 Filing date: 20090331 Expiry date: 20120424 |
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