GB0215676D0
(en)
*
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
GB0325031D0
(en)
*
|
2003-10-27 |
2003-12-03 |
Novartis Ag |
Organic compounds
|
CA2546189C
(en)
*
|
2003-11-18 |
2013-04-23 |
Novartis Ag |
Inhibitors of the mutant form of kit
|
JPWO2005063720A1
(ja)
*
|
2003-12-25 |
2007-07-19 |
日本新薬株式会社 |
アミド誘導体及び医薬
|
KR20120091378A
(ko)
|
2004-03-23 |
2012-08-17 |
노파르티스 아게 |
제약 조성물
|
MXPA06012613A
(es)
*
|
2004-05-07 |
2007-01-31 |
Amgen Inc |
Derivados heterociclicos nitrogenados como moduladores de proteina cinasa y uso para el tratamiento de angiogenesis y cancer.
|
AU2005309019A1
(en)
*
|
2004-11-24 |
2006-06-01 |
Novartis Ag |
Combinations of JAK inhibitors and at least one of Bcr-Abl, Flt-3, FAK or RAF kinase inhibitors
|
CN1939910A
(zh)
*
|
2004-12-31 |
2007-04-04 |
孙飘扬 |
氨基嘧啶类化合物及其盐和其制备方法与药物用途
|
DK1843771T3
(da)
*
|
2005-01-28 |
2012-01-16 |
Novartis Ag |
Anvendelse af pyrimidylaminobenzamider til behandling af sygdomme, der responderer på modulation af Tie-2-kinase-aktiviteten
|
MX2007011866A
(es)
*
|
2005-02-25 |
2007-10-10 |
Novartis Ag |
Combinacion farmaceutica de inhibidores de bcr-abl y raf.
|
CA2606068C
(en)
*
|
2005-05-02 |
2013-10-29 |
Novartis Ag |
Pyrimidylaminobenzamide derivatives for hypereosinophilic syndrome
|
CN101171013A
(zh)
*
|
2005-05-02 |
2008-04-30 |
诺瓦提斯公司 |
嘧啶基氨基苯甲酰胺衍生物用于治疗全身性肥大细胞增多症的应用
|
EP2559690B1
(en)
|
2005-05-10 |
2016-03-30 |
Incyte Holdings Corporation |
Modulators of indoleamine 2,3-dioxygenase and methods of using the same
|
DE602006012313D1
(de)
*
|
2005-06-03 |
2010-04-01 |
Novartis Ag |
Kombination aus pyrimidylaminobenzamid-verbindungen und imatinib zur behandlung oder verhinderung proliferativer erkrankungen
|
AU2013205820B2
(en)
*
|
2005-06-09 |
2015-11-26 |
Novartis Ag |
Process for the synthesis of organic compounds
|
ES2356257T3
(es)
*
|
2005-06-09 |
2011-04-06 |
Novartis Ag |
Proceso para la síntesis del 5-(metil-1h-imidazol-1-il)-3-(trifluorometil)-bencenoamina.
|
SA06270147B1
(ar)
|
2005-06-09 |
2009-12-22 |
نوفارتيس ايه جي |
عملية لتخليق 5-(مثيل–1h–إيميدازول–1-يل )–3-(ثلاثي فلـورو مثيل)–بنزامـين
|
MY146795A
(en)
|
2005-06-09 |
2012-09-28 |
Novartis Ag |
Process for the synthesis of organic compounds
|
GT200600207A
(es)
*
|
2005-06-09 |
2007-01-15 |
Novartis Ag |
Proceso para la síntesis de compuestos orgánicos
|
US20060281788A1
(en)
|
2005-06-10 |
2006-12-14 |
Baumann Christian A |
Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor
|
US8071768B2
(en)
|
2005-06-10 |
2011-12-06 |
Janssen Pharmaceutica, N.V. |
Alkylquinoline and alkylquinazoline kinase modulators
|
US7825244B2
(en)
|
2005-06-10 |
2010-11-02 |
Janssen Pharmaceutica Nv |
Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
|
CA2612227C
(en)
*
|
2005-06-14 |
2014-04-22 |
Taigen Biotechnology Co., Ltd. |
Pyrimidine compounds
|
US8193206B2
(en)
|
2005-06-14 |
2012-06-05 |
Taigen Biotechnology Co., Ltd. |
Pyrimidine compounds
|
GT200600316A
(es)
*
|
2005-07-20 |
2007-04-02 |
|
Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
|
AU2012203844B2
(en)
*
|
2005-07-20 |
2014-12-11 |
Novartis Ag |
Salts of 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
|
EP1909794A2
(en)
|
2005-07-20 |
2008-04-16 |
Novartis AG |
Combination of organic compounds
|
BRPI0613868A2
(pt)
*
|
2005-07-20 |
2011-02-15 |
Novartis Ag |
compostos orgánicos
|
GT200600315A
(es)
*
|
2005-07-20 |
2007-03-19 |
|
Formas cristalinas de 4-metilo-n-[3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo]-3-(4-pyridina-3-ilo-pirimidina-2-iloamino)-benzamida
|
KR100674813B1
(ko)
|
2005-08-05 |
2007-01-29 |
일양약품주식회사 |
N-페닐-2-피리미딘-아민 유도체 및 그의 제조방법
|
JP2009504673A
(ja)
*
|
2005-08-11 |
2009-02-05 |
ノバルティス アクチエンゲゼルシャフト |
ピリミジルアミノベンズアミド化合物であるタンパク質キナーゼ阻害剤および17−aagのようなhsp90阻害剤を含む組合せ
|
CA2617979A1
(en)
*
|
2005-08-11 |
2007-02-22 |
Novartis Ag |
Combination of a pyrimydlaminobenzamide tyrosine kinase inhibitor and a histone deacetylase inhibitor
|
US20070149506A1
(en)
|
2005-09-22 |
2007-06-28 |
Arvanitis Argyrios G |
Azepine inhibitors of Janus kinases
|
US20080255171A1
(en)
*
|
2005-10-07 |
2008-10-16 |
Manley Paul W |
Combination of Nilotinib with Farnesyl Transferase Inhibitors
|
NZ595182A
(en)
|
2005-10-18 |
2012-12-21 |
Janssen Pharmaceutica Nv |
Pharmaceutical uses of 4-cyano-1H-imidazole-2-carboxylic acid { 2-cyclohex-1-enyl-4-[1-(2-dimethylamino-acetyl)-piperidin-4-yl]-phenyl} -amide
|
WO2007051862A1
(en)
*
|
2005-11-07 |
2007-05-10 |
Novartis Ag |
Combination of organic compounds
|
US20090099197A1
(en)
*
|
2005-11-15 |
2009-04-16 |
Bristol-Myers Squibb Company |
Methods of Identifying and Treating Individuals Exhibiting MDR-1 Overexpression With Protein Tyrosine Kinase Inhibitors and Combinations Thereof
|
ES2391199T3
(es)
*
|
2005-12-06 |
2012-11-22 |
Novartis Ag |
Derivados de pirimidilaminobenzamida para el tratamiento de neurofibromatosis
|
HUE030235T2
(en)
|
2005-12-13 |
2017-04-28 |
Incyte Holdings Corp |
Heteroaryl-substituted pyrrolo [2,3-b] pyridines and pyrrolo [2,3-b] pyrimidines as Janus kinase inhibitors
|
US20090306094A1
(en)
*
|
2006-03-17 |
2009-12-10 |
Bristol-Myers Squibb Company |
Methods Of Identifying And Treating Individuals Exhibiting Mutant Bcr/Abl Kinase Polypeptides
|
CN101415424B
(zh)
*
|
2006-04-05 |
2012-12-05 |
诺瓦提斯公司 |
用于治疗癌症、包含bcr-abl/c-kit/pdgf-r tk抑制剂的组合
|
PT2007391E
(pt)
*
|
2006-04-07 |
2013-03-11 |
Novartis Ag |
Combinação compreendendo: a) um composto de pirimidil-aminobenzamida e b) um inibidor da cinase thr315ile
|
AU2011202833B2
(en)
*
|
2006-04-07 |
2012-05-24 |
Novartis Ag |
Combination comprising a) a pyrimidylaminobenzamide compound, and b) a Thr315lle kinase inhibitor
|
UA93085C2
(en)
|
2006-04-20 |
2011-01-10 |
Янссен Фармацевтика Н.В. |
Inhibitors of c-fms kinase
|
US8697716B2
(en)
|
2006-04-20 |
2014-04-15 |
Janssen Pharmaceutica Nv |
Method of inhibiting C-KIT kinase
|
EP2021335B1
(en)
|
2006-04-20 |
2011-05-25 |
Janssen Pharmaceutica N.V. |
Heterocyclic compounds as inhibitors of c-fms kinase
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
US8093259B2
(en)
|
2006-05-25 |
2012-01-10 |
Novartis Ag |
4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]-benzamide for treatment of melanoma
|
DE602007012122D1
(de)
|
2006-09-22 |
2011-03-03 |
Novartis Ag |
Optimierung der behandlung philadelphia-positiver leukämie mit abl-tyrosinkinasehemmer imatinib
|
EP1923053A1
(en)
*
|
2006-09-27 |
2008-05-21 |
Novartis AG |
Pharmaceutical compositions comprising nilotinib or its salt
|
US8916552B2
(en)
|
2006-10-12 |
2014-12-23 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
EP2073807A1
(en)
|
2006-10-12 |
2009-07-01 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
CA2668190A1
(en)
*
|
2006-11-03 |
2008-05-15 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
EP2100874A4
(en)
*
|
2006-11-13 |
2014-04-09 |
Toray Finechemicals Co Ltd |
PROCESS FOR PRODUCING 2,2'-BIS (TRIFLUOROMETHYL) -4,4'-DIAMINOBIPHENYL
|
MX2009006444A
(es)
*
|
2006-12-21 |
2009-06-26 |
Astellas Pharma Inc |
Metodo para producir derivado de c-glucosido e intermediario sintetico del mismo.
|
WO2008079965A1
(en)
|
2006-12-22 |
2008-07-03 |
Incyte Corporation |
Substituted heterocycles as janus kinase inhibitors
|
CN101720322A
(zh)
|
2007-05-04 |
2010-06-02 |
Irm责任有限公司 |
作为c-kit和pdgfr激酶抑制剂的化合物和组合物
|
US8268850B2
(en)
|
2007-05-04 |
2012-09-18 |
Irm Llc |
Pyrimidine derivatives and compositions as C-kit and PDGFR kinase inhibitors
|
TWI433677B
(zh)
*
|
2007-06-04 |
2014-04-11 |
Avila Therapeutics Inc |
雜環化合物及其用途
|
EP2166858A4
(en)
|
2007-06-07 |
2011-08-03 |
Intra Cellular Therapies Inc |
NEW HETEROCYCLIC COMPOUNDS AND ITS USE
|
JP5559043B2
(ja)
|
2007-06-07 |
2014-07-23 |
イントラ−セルラー・セラピーズ・インコーポレイテッド |
新規ヘテロ環化合物およびその使用
|
WO2008153947A2
(en)
|
2007-06-07 |
2008-12-18 |
Amgen Inc. |
Heterocyclic compounds as raf kinase modulators
|
CL2008001709A1
(es)
|
2007-06-13 |
2008-11-03 |
Incyte Corp |
Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
|
EP3070090B1
(en)
|
2007-06-13 |
2018-12-12 |
Incyte Holdings Corporation |
Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
|
ES2368876T3
(es)
|
2007-08-22 |
2011-11-23 |
Irm Llc |
Derivados de 2-heteroarilaminopirimidina como inhibidores de cinasa.
|
CN101784530A
(zh)
|
2007-08-22 |
2010-07-21 |
Irm责任有限公司 |
作为激酶抑制剂的5-(4-(卤代烷氧基)苯基)嘧啶-2-胺化合物和组合物
|
US8530480B2
(en)
*
|
2007-09-04 |
2013-09-10 |
The Scripps Research Institute |
Substituted pyrimidinyl-amines as protein kinase inhibitors
|
JO3240B1
(ar)
|
2007-10-17 |
2018-03-08 |
Janssen Pharmaceutica Nv |
c-fms مثبطات كيناز
|
NZ585139A
(en)
|
2007-11-16 |
2012-05-25 |
Incyte Corp |
4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as jak inhibitors
|
PL2240172T3
(pl)
|
2007-12-21 |
2014-08-29 |
Novartis Ag |
Kombinacja nilotynibu i chlorambucylu do leczenia przewlekłej białaczki limfocytowej
|
ES2602577T3
(es)
|
2008-03-11 |
2017-02-21 |
Incyte Holdings Corporation |
Derivados de azetidina y ciclobutano como inhibidores de JAK
|
CA2722326A1
(en)
|
2008-04-24 |
2009-10-29 |
Incyte Corporation |
Macrocyclic compounds and their use as kinase inhibitors
|
KR101927291B1
(ko)
|
2008-07-08 |
2018-12-10 |
인사이트 홀딩스 코포레이션 |
인돌아민 2,3-디옥시게나아제의 억제제로서의 1,2,5-옥사디아졸
|
EP2305667A3
(en)
|
2008-07-17 |
2011-05-11 |
Teva Pharmaceutical Industries Ltd. |
Nilotinib intermediates and preparation thereof
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
MX2011001668A
(es)
*
|
2008-08-13 |
2011-03-25 |
Novartis Ag |
Tratamiento de hipertension arterial pulmonar.
|
KR20100021321A
(ko)
*
|
2008-08-14 |
2010-02-24 |
일양약품주식회사 |
Ν-페닐-2-피리미딘-아민 유도체의 제조방법
|
JP5906086B2
(ja)
|
2008-08-15 |
2016-04-20 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Fab関連疾患の治療に用いるためのプリン誘導体
|
CL2009001884A1
(es)
|
2008-10-02 |
2010-05-14 |
Incyte Holdings Corp |
Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
|
JP5486012B2
(ja)
|
2008-11-05 |
2014-05-07 |
テバ ファーマシューティカル インダストリーズ リミティド |
ニロチニブHCl結晶形
|
EP2186514B1
(en)
*
|
2008-11-14 |
2016-06-29 |
Kinki University |
Treatment of Malignant Peripheral Nerve Sheath Tumors
|
WO2010060074A1
(en)
*
|
2008-11-24 |
2010-05-27 |
Teva Pharmaceutical Industries Ltd. |
Preparation of nilotinib and intermediates thereof
|
TWI508965B
(zh)
|
2008-12-23 |
2015-11-21 |
Boehringer Ingelheim Int |
有機化合物的鹽形式
|
CN101759683B
(zh)
*
|
2008-12-25 |
2011-12-28 |
哈尔滨誉衡药业股份有限公司 |
二氢化茚酰胺化合物制备方法、包含其的药物组合物、及其作为蛋白激酶抑制剂的应用
|
TW201036975A
(en)
|
2009-01-07 |
2010-10-16 |
Boehringer Ingelheim Int |
Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
|
WO2010085597A1
(en)
|
2009-01-23 |
2010-07-29 |
Incyte Corporation |
Macrocyclic compounds and their use as kinase inhibitors
|
TWI466672B
(zh)
|
2009-01-29 |
2015-01-01 |
Boehringer Ingelheim Int |
小兒科病人糖尿病之治療
|
CN106177958A
(zh)
|
2009-02-13 |
2016-12-07 |
勃林格殷格翰国际有限公司 |
包含dpp‑4抑制剂(利拉列汀)任选地组合其它抗糖尿病药的抗糖尿病药物
|
WO2010096395A1
(en)
*
|
2009-02-18 |
2010-08-26 |
Syntech Solution Llc |
Amides as kinase inhibitors
|
CA2753637A1
(en)
|
2009-03-06 |
2010-09-10 |
Novartis Ag |
Use of pyrimidylaminobenzamide derivatives for the treatment of disorders mediated by the leucine zipper- and sterile alpha motif-containing kinase (zak)
|
AR076794A1
(es)
|
2009-05-22 |
2011-07-06 |
Incyte Corp |
Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo [2,3-d]pirimidinas y pirrol-3-il-pirrolo [2,3-d ]pirimidinas como inhibidores de la quinasa janus y composiciones farmaceuticas que los contienen
|
EA020494B1
(ru)
|
2009-05-22 |
2014-11-28 |
Инсайт Корпорейшн |
3-[4-(7H-ПИРРОЛО[2,3-d]ПИРИМИДИН-4-ИЛ)-1H-ПИРАЗОЛ-1-ИЛ]ОКТАН- ИЛИ ГЕПТАННИТРИЛ КАК JAK-ИНГИБИТОРЫ
|
TW201102068A
(en)
*
|
2009-06-02 |
2011-01-16 |
Novartis Ag |
Treatment of ophthalmologic disorders mediated by alpha-carbonic anhydrase isoforms
|
US20110053968A1
(en)
*
|
2009-06-09 |
2011-03-03 |
Auspex Pharmaceuticals, Inc. |
Aminopyrimidine inhibitors of tyrosine kinase
|
NZ597050A
(en)
|
2009-06-29 |
2014-02-28 |
Incyte Corp |
Pyrimidinones as pi3k inhibitors
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
SG10201507362TA
(en)
|
2009-08-05 |
2015-10-29 |
Intra Cellular Therapies Inc |
Novel Regulatory Proteins And Inhibitors
|
AR078012A1
(es)
|
2009-09-01 |
2011-10-05 |
Incyte Corp |
Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus
|
WO2011033307A1
(en)
|
2009-09-17 |
2011-03-24 |
Generics [Uk] Limited |
Nilotinib dihydrochloride salt
|
EP2482812B1
(en)
|
2009-10-02 |
2023-01-11 |
Boehringer Ingelheim International GmbH |
Pharmaceutical compositions comprising bi-1356 and metformin
|
WO2011044481A1
(en)
|
2009-10-09 |
2011-04-14 |
Incyte Corporation |
Hydroxyl, keto, and glucuronide derivatives of 3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
|
MX2012004078A
(es)
|
2009-10-09 |
2012-07-25 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de gpr119.
|
EP2490690A1
(en)
*
|
2009-10-23 |
2012-08-29 |
Novartis AG |
Method of treating proliferative disorders and other pathological conditions mediated by bcr-abl, c-kit, ddr1, ddr2 or pdgf-r kinase activity
|
JO3634B1
(ar)
*
|
2009-11-17 |
2020-08-27 |
Novartis Ag |
طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r
|
JP2013512229A
(ja)
|
2009-11-27 |
2013-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
遺伝子型が同定された糖尿病患者のリナグリプチン等のddp−iv阻害薬による治療
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
US8759359B2
(en)
|
2009-12-18 |
2014-06-24 |
Incyte Corporation |
Substituted heteroaryl fused derivatives as PI3K inhibitors
|
US8680108B2
(en)
|
2009-12-18 |
2014-03-25 |
Incyte Corporation |
Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors
|
HUE045270T2
(hu)
|
2010-01-05 |
2019-12-30 |
Inst Nat Sante Rech Med |
FLT3 receptor anatgonisták fájdalom rendellenességek kezelésére
|
KR101750125B1
(ko)
|
2010-01-12 |
2017-06-22 |
에이비 사이언스 |
티아졸 및 옥사졸 키나제 저해제
|
IN2010KO00035A
(zh)
|
2010-01-15 |
2016-09-02 |
|
|
BR112012020693B1
(pt)
|
2010-02-18 |
2020-05-12 |
Incyte Holdings Corporation |
Derivados de ciclobutano e metilciclobutano como inibidores de janus quinase e composição que os compreende
|
MX347851B
(es)
|
2010-03-10 |
2017-05-16 |
Incyte Corp |
Derivados de piperidin-4-il azetidina como inhibidores de janus cinasa 1 (jak1).
|
WO2011113947A1
(en)
|
2010-03-18 |
2011-09-22 |
Boehringer Ingelheim International Gmbh |
Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
|
EP2558463A1
(en)
|
2010-04-14 |
2013-02-20 |
Incyte Corporation |
Fused derivatives as i3 inhibitors
|
EP2558098A2
(en)
|
2010-04-16 |
2013-02-20 |
Novartis AG |
Treatment of endocrine resistant breast cancer
|
EP2382976A1
(en)
|
2010-04-30 |
2011-11-02 |
Hiroshima University |
Use of pdgf-r inhibitors for the treatment of lymph node metastasis of gastric cancer
|
NZ602921A
(en)
|
2010-05-05 |
2016-01-29 |
Boehringer Ingelheim Int |
Combination therapy comprising the administration of a glp-1 receptor agonist and a ddp-4 inhibitor
|
EP3087972A1
(en)
|
2010-05-21 |
2016-11-02 |
Incyte Holdings Corporation |
Topical formulation for a jak inhibitor
|
WO2011163195A1
(en)
|
2010-06-21 |
2011-12-29 |
Incyte Corporation |
Fused pyrrole derivatives as pi3k inhibitors
|
KR20130042498A
(ko)
|
2010-06-21 |
2013-04-26 |
테바 파마슈티컬 인더스트리즈 리미티드 |
닐로티닙 염 및 이의 결정형
|
MX2012014247A
(es)
|
2010-06-24 |
2013-01-18 |
Boehringer Ingelheim Int |
Terapia para la diabetes.
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
WO2012027716A1
(en)
|
2010-08-27 |
2012-03-01 |
Collabrx, Inc. |
Method to treat melanoma in braf inhibitor-resistant subjects
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
EP2640725B1
(en)
|
2010-11-19 |
2015-01-07 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
|
SG190839A1
(en)
|
2010-11-19 |
2013-07-31 |
Incyte Corp |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
|
EP2648519A4
(en)
*
|
2010-11-26 |
2014-04-30 |
Hetero Research Foundation |
NEW POLYMORPH OF NILOTINIB HYDROCHLORIDE
|
AR084366A1
(es)
|
2010-12-20 |
2013-05-08 |
Incyte Corp |
N-(1-(fenil sustituido)etil)-9h-purin-6-aminas como inhibidores de pi3k
|
EA024194B8
(ru)
|
2011-01-21 |
2016-11-30 |
Сан Фарма Адвансед Ресьорч Компани Лтд |
Содержащие диарилацетиленгидразид ингибиторы тирозинкиназы
|
KR102024948B1
(ko)
|
2011-02-18 |
2019-11-04 |
노파르티스 파르마 아게 |
mTOR/JAK 저해제 병용 요법
|
WO2012118599A1
(en)
|
2011-02-28 |
2012-09-07 |
Emory University |
C-abl tyrosine kinase inhibitors useful for inhibiting filovirus replication
|
US9108984B2
(en)
|
2011-03-14 |
2015-08-18 |
Incyte Corporation |
Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors
|
WO2012135009A1
(en)
|
2011-03-25 |
2012-10-04 |
Incyte Corporation |
Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
|
LT2717883T
(lt)
|
2011-05-02 |
2017-04-25 |
Stichting Vumc |
Apsauga nuo endotelio barjero disfunkcijos, slopinant su abl susijusio geno (arg) tirozino kinazę
|
AR086983A1
(es)
|
2011-06-20 |
2014-02-05 |
Incyte Corp |
Derivados de azetidinil fenil, piridil o pirazinil carboxamida como inhibidores de jak
|
EP3517539B1
(en)
|
2011-07-15 |
2022-12-14 |
Boehringer Ingelheim International GmbH |
Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes
|
WO2013023119A1
(en)
|
2011-08-10 |
2013-02-14 |
Novartis Pharma Ag |
JAK P13K/mTOR COMBINATION THERAPY
|
CN102321073A
(zh)
*
|
2011-08-12 |
2012-01-18 |
西安交通大学 |
一种尼罗替尼的制备方法
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為jak抑制劑之環己基氮雜環丁烷衍生物
|
BR122019020716B1
(pt)
|
2011-09-02 |
2021-02-17 |
Incyte Holdings Corporation |
heterociclilaminas como inibidores de pi3k e composição farmacêutica que as compreende
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
WO2013063003A1
(en)
|
2011-10-28 |
2013-05-02 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
KR20140096035A
(ko)
|
2011-10-28 |
2014-08-04 |
노파르티스 아게 |
위장 기질 종양을 치료하는 방법
|
GB2496135B
(en)
|
2011-11-01 |
2015-03-18 |
Valirx Plc |
Inhibitors of the interaction between a Src family kinase and an androgen receptor or estradiol receptor for treatment of endometriosis
|
WO2013068836A1
(en)
|
2011-11-07 |
2013-05-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A ddr1 antagonist or an inhibitor of ddr1 gene expression for use in the prevention or treatment of crescentic glomerulonephritis
|
JP6275645B2
(ja)
*
|
2011-11-14 |
2018-02-07 |
ノバルティス アーゲー |
4−メチル−3−[[4−(3−ピリジニル)−2−ピリミジニル]アミノ]−n−[5−(4−メチル−1h−イミダゾール−1−イル)−3−(トリフルオロメチル)フェニル]ベンズアミドの即放性製剤
|
CN103172617A
(zh)
*
|
2011-12-20 |
2013-06-26 |
天津市国际生物医药联合研究院 |
1,5-二取代-1,2,3-三氮唑三氟甲基类化合物的应用
|
US20130172244A1
(en)
|
2011-12-29 |
2013-07-04 |
Thomas Klein |
Subcutaneous therapeutic use of dpp-4 inhibitor
|
ES2564969T3
(es)
|
2012-02-09 |
2016-03-30 |
Natco Pharma Limited |
Proceso para la preparación de clorhidrato de nilotinib
|
US9061028B2
(en)
|
2012-02-15 |
2015-06-23 |
Natco Pharma Limited |
Process for the preparation of Nilotinib
|
ES2857649T3
(es)
|
2012-03-01 |
2021-09-29 |
Array Biopharma Inc |
Inhibidores de serina/treonina cinasa
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
JP6177768B2
(ja)
|
2012-04-24 |
2017-08-09 |
中外製薬株式会社 |
ベンズアミド誘導体
|
BR112014026305A2
(pt)
|
2012-04-24 |
2017-06-27 |
Chugai Pharmaceutical Co Ltd |
derivado de quinazolidinadiona
|
US20130303554A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in sirs and/or sepsis
|
WO2013171167A1
(en)
|
2012-05-14 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
|
EA201492005A1
(ru)
*
|
2012-05-15 |
2015-04-30 |
Новартис Аг |
Бензамидные производные для ингибирования активности abl1, abl2 и bcr-abl1
|
MX357305B
(es)
|
2012-05-15 |
2018-07-04 |
Novartis Ag |
Compuestos y composiciones para inhibir la actividad de abl-1, abl-2, y bcr-abl1.
|
CN104302634B
(zh)
|
2012-05-15 |
2017-02-08 |
诺华股份有限公司 |
用于抑制abl1、abl2和bcr‑abl1的活性的苯甲酰胺衍生物
|
SI2861579T1
(en)
*
|
2012-05-15 |
2018-05-31 |
Novartis Ag |
Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
|
AR091079A1
(es)
|
2012-05-18 |
2014-12-30 |
Incyte Corp |
Derivados de pirrolopirimidina y pirrolopiridina sustituida con piperidinilciclobutilo como inhibidores de jak
|
WO2013174768A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in the treatment of autoimmune diabetes, particularly lada
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
US9056860B2
(en)
*
|
2012-06-05 |
2015-06-16 |
Gilead Pharmasset Llc |
Synthesis of antiviral compound
|
PT3176170T
(pt)
|
2012-06-13 |
2019-02-05 |
Incyte Holdings Corp |
Compostos tricíclicos substituídos como inibidores de fgfr
|
EP2872142A1
(en)
|
2012-07-11 |
2015-05-20 |
Novartis AG |
Method of treating gastrointestinal stromal tumors
|
US20140235631A1
(en)
|
2012-07-27 |
2014-08-21 |
Antonius Martinus Gustave Bunt |
Efflux inhibitor compositions and methods of treatment using the same
|
JP6359537B2
(ja)
|
2012-08-07 |
2018-07-18 |
ヤンセン ファーマシューティカ エヌ.ベー. |
複素環エステル誘導体の調製プロセス
|
JOP20180012A1
(ar)
|
2012-08-07 |
2019-01-30 |
Janssen Pharmaceutica Nv |
عملية السلفنة باستخدام نونافلوروبوتانيسولفونيل فلوريد
|
KR101738063B1
(ko)
|
2012-09-21 |
2017-05-19 |
아로그 파마슈티칼스, 인코퍼레이티드 |
구조적으로 활성인 인산화된 flt3 키나제의 억제 방법
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
MX2015004947A
(es)
*
|
2012-10-19 |
2016-02-22 |
Basf Se |
Sistema cristalino multicomponente que comprende nilotinib y formadores de cocristal seleccionados.
|
NZ707495A
(en)
|
2012-11-01 |
2019-01-25 |
Incyte Holdings Corp |
Tricyclic fused thiophene derivatives as jak inhibitors
|
KR20220162825A
(ko)
|
2012-11-15 |
2022-12-08 |
인사이트 홀딩스 코포레이션 |
룩솔리티니브의 서방성 제형
|
BR112015016282A2
(pt)
|
2013-01-07 |
2017-07-11 |
Arog Pharmaceuticals Inc |
crenolanibe para tratamento de distúrbios proliferativos de flt3 mutado
|
CN103910714A
(zh)
*
|
2013-01-09 |
2014-07-09 |
天津泰瑞倍药研科技有限公司 |
氟代环丁烷基咪唑类化合物
|
WO2014124860A1
(en)
|
2013-02-14 |
2014-08-21 |
Boehringer Ingelheim International Gmbh |
Specific pde4b-inhibitors for the treatment of diabetes mellitus
|
TWI657090B
(zh)
|
2013-03-01 |
2019-04-21 |
英塞特控股公司 |
吡唑并嘧啶衍生物治療PI3Kδ 相關病症之用途
|
AU2014225938B2
(en)
|
2013-03-06 |
2018-07-19 |
Incyte Holdings Corporation |
Processes and intermediates for making a JAK inhibitor
|
CN105188706A
(zh)
|
2013-03-15 |
2015-12-23 |
勃林格殷格翰国际有限公司 |
利格列汀在心脏和肾脏保护性抗糖尿病治疗中的用途
|
SG10201708520YA
(en)
|
2013-04-19 |
2017-12-28 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
WO2014174496A1
(en)
|
2013-04-25 |
2014-10-30 |
Ranbaxy Laboratories Limited |
Pharmaceutical gastro-retentive solid oral dosage form of nilotinib
|
GB2513615A
(en)
|
2013-05-01 |
2014-11-05 |
Cancer Rec Tech Ltd |
Medical use
|
DK3786162T3
(da)
|
2013-05-17 |
2023-10-09 |
Incyte Holdings Corp |
Bipyrazolderivater som jak-inhibitorer
|
CN103288804A
(zh)
*
|
2013-05-24 |
2013-09-11 |
苏州明锐医药科技有限公司 |
一种尼洛替尼的制备方法
|
KR20160045081A
(ko)
|
2013-08-07 |
2016-04-26 |
인사이트 코포레이션 |
Jak1 억제제용 지속 방출 복용 형태
|
SG11201601119XA
(en)
|
2013-08-20 |
2016-03-30 |
Incyte Corp |
Survival benefit in patients with solid tumors with elevated c-reactive protein levels
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
CA2927830A1
(en)
|
2013-10-23 |
2015-04-30 |
Chugai Seiyaku Kabushiki Kaisha |
Quinazolinone and isoquinolinone derivative
|
US10463658B2
(en)
|
2013-10-25 |
2019-11-05 |
Videra Pharmaceuticals, Llc |
Method of inhibiting FLT3 kinase
|
WO2015092624A1
(en)
|
2013-12-16 |
2015-06-25 |
Ranbaxy Laboratories Limited |
Nilotinib mono-oxalate and its crystalline form
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
ES2688553T3
(es)
|
2014-02-28 |
2018-11-05 |
Incyte Corporation |
Inhibidores de JAK1 para el tratamiento de síndromes mielodisplásicos
|
TWI777174B
(zh)
|
2014-03-14 |
2022-09-11 |
瑞士商諾華公司 |
針對lag-3之抗體分子及其用途
|
US10064866B2
(en)
|
2014-04-08 |
2018-09-04 |
Incyte Corporation |
Treatment of B-cell malignancies by a combination JAK and PI3K inhibitors
|
TW201625643A
(zh)
|
2014-04-30 |
2016-07-16 |
英塞特公司 |
製備jak1抑制劑之方法及其新形式
|
WO2015184305A1
(en)
|
2014-05-30 |
2015-12-03 |
Incyte Corporation |
TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1
|
US10077277B2
(en)
|
2014-06-11 |
2018-09-18 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors
|
RU2710928C2
(ru)
|
2014-07-31 |
2020-01-14 |
Инсерм (Институт Насьональ Де Ла Сант Эт Де Ла Решерш Медикаль) |
Антагонисты рецептора flt3
|
US10045987B2
(en)
|
2014-08-28 |
2018-08-14 |
Codexis, Inc. |
Imidazoyl anilide derivatives and methods of use
|
WO2016035023A1
(en)
|
2014-09-03 |
2016-03-10 |
Novartis Ag |
Pharmaceutical combinations and their use
|
WO2016040892A1
(en)
|
2014-09-13 |
2016-03-17 |
Novartis Ag |
Combination therapies
|
EP3200775B1
(en)
|
2014-10-03 |
2019-11-20 |
Novartis AG |
Combination therapies
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
WO2016059220A1
(en)
|
2014-10-16 |
2016-04-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Tcr-activating agents for use in the treatment of t-all
|
CN104592122B
(zh)
*
|
2014-12-09 |
2018-01-23 |
凯莱英医药集团(天津)股份有限公司 |
3‑(4‑甲基‑1h‑咪唑‑1‑基)‑5‑(三氟甲基)苯胺的制备方法
|
US9586949B2
(en)
|
2015-02-09 |
2017-03-07 |
Incyte Corporation |
Aza-heteroaryl compounds as PI3K-gamma inhibitors
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
TWI712601B
(zh)
|
2015-02-20 |
2020-12-11 |
美商英塞特公司 |
作為fgfr抑制劑之雙環雜環
|
MD3262046T2
(ro)
|
2015-02-27 |
2021-03-31 |
Incyte Corp |
Săruri de inhibitori ai PI3K și procedee pentru prepararea lor
|
CN105985293B
(zh)
*
|
2015-03-04 |
2018-04-03 |
埃斯特维华义制药有限公司 |
尼洛替尼中间体的制备方法
|
US10449211B2
(en)
|
2015-03-10 |
2019-10-22 |
Aduro Biotech, Inc. |
Compositions and methods for activating “stimulator of interferon gene”—dependent signalling
|
US10301282B2
(en)
|
2015-03-20 |
2019-05-28 |
Cipla Limited |
Polymorphic form X of nilotinib dihydrochloride hydrate
|
WO2016183062A1
(en)
|
2015-05-11 |
2016-11-17 |
Incyte Corporation |
Salts of (s)-7-(1-(9h-purin-6-ylamino)ethyl)-6-(3-fluorophenyl)-3-methyl-5h-thiazolo[3,2-a]pyrimidin-5-one
|
US9732097B2
(en)
|
2015-05-11 |
2017-08-15 |
Incyte Corporation |
Process for the synthesis of a phosphoinositide 3-kinase inhibitor
|
WO2016183063A1
(en)
|
2015-05-11 |
2016-11-17 |
Incyte Corporation |
Crystalline forms of a pi3k inhibitor
|
EP3095782A1
(en)
|
2015-05-18 |
2016-11-23 |
Esteve Química, S.A. |
New method for preparing 3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
|
CN104860929B
(zh)
*
|
2015-05-26 |
2017-10-31 |
凯莱英医药集团(天津)股份有限公司 |
尼洛替尼的制备方法
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
EP3964528A1
(en)
|
2015-07-29 |
2022-03-09 |
Novartis AG |
Combination therapies comprising antibody molecules to lag-3
|
AU2016348391A1
(en)
|
2015-11-03 |
2018-05-17 |
Janssen Biotech, Inc. |
Antibodies specifically binding TIM-3 and their uses
|
AR106595A1
(es)
|
2015-11-06 |
2018-01-31 |
Incyte Corp |
COMPUESTOS HETEROCÍCLICOS COMO INHIBIDORES DE PI3K-g
|
AU2016369537B2
(en)
|
2015-12-17 |
2024-03-14 |
Novartis Ag |
Antibody molecules to PD-1 and uses thereof
|
CN106905298A
(zh)
*
|
2015-12-22 |
2017-06-30 |
江苏先声药业有限公司 |
盐酸尼洛替尼杂质的制备方法
|
ES2833955T3
(es)
|
2016-01-05 |
2021-06-16 |
Incyte Corp |
Piridinas sustituidas con pirazol/imidazol como inhibidores de PI3K-Gamma
|
BR112018067392A2
(pt)
|
2016-03-01 |
2019-01-02 |
Propellon Therapeutics Inc |
inibidores de ligação entre proteínas wdr5
|
AU2017226005A1
(en)
|
2016-03-01 |
2018-09-06 |
Propellon Therapeutics Inc. |
Inhibitors of WDR5 protein-protein binding
|
CN105801559B
(zh)
*
|
2016-04-28 |
2019-03-01 |
北京化工大学 |
4-甲基-3-[[4-(3-吡啶基)-2-嘧啶基]氨基]苯甲酸乙酯的制备方法
|
EP3254698A1
(en)
|
2016-06-08 |
2017-12-13 |
Universite De Montpellier |
Flt3 receptor inhibitor at low dosage for the treatment of neuropathic pain
|
EP3468562A1
(en)
|
2016-06-10 |
2019-04-17 |
Boehringer Ingelheim International GmbH |
Combinations of linagliptin and metformin
|
WO2017223414A1
(en)
|
2016-06-24 |
2017-12-28 |
Incyte Corporation |
HETEROCYCLIC COMPOUNDS AS PI3K-γ INHIBITORS
|
WO2018002958A1
(en)
|
2016-06-30 |
2018-01-04 |
Sun Pharma Advanced Research Company Limited |
Novel hydrazide containing compounds as btk inhibitors
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
US11078541B2
(en)
|
2016-11-02 |
2021-08-03 |
Arog Pharmaceuticals, Inc. |
Crenolanib for treating FLT3 mutated proliferative disorders associated mutations
|
US11426406B2
(en)
|
2017-02-09 |
2022-08-30 |
Georgetown University |
Compositions and methods for treating lysosomal storage disorders
|
US11091466B2
(en)
|
2017-03-17 |
2021-08-17 |
Cardio Therapeutics Pty Ltd |
Heterocyclic inhibitors of PCSK9
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
EP3404025B1
(en)
|
2017-05-16 |
2019-12-04 |
F.I.S.- Fabbrica Italiana Sintetici S.p.A. |
Process for the preparation of pure nilotinib and its salt
|
US20200171022A1
(en)
|
2017-05-17 |
2020-06-04 |
Inserm (Institut National De La Santé Et Da La Recherche Médicale) |
Flt3 inhibitors for improving pain treatments by opioids
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
CN107188887A
(zh)
*
|
2017-06-15 |
2017-09-22 |
苏州立新制药有限公司 |
一种尼洛替尼氧化降解杂质及其制备方法
|
EP3642240A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
WO2019057649A1
(en)
|
2017-09-19 |
2019-03-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA
|
EP4006034A1
(en)
|
2017-10-18 |
2022-06-01 |
Incyte Corporation |
Condensed imidazole derivatives substituted by tertiary hydroxy groups as pi3k-gamma inhibitors
|
TW201924683A
(zh)
|
2017-12-08 |
2019-07-01 |
美商英塞特公司 |
用於治療骨髓增生性贅瘤的低劑量組合療法
|
CZ2017821A3
(cs)
|
2017-12-20 |
2019-07-03 |
Zentiva, K.S. |
Léková forma obsahující krystalický nilotinib
|
US11306079B2
(en)
|
2017-12-21 |
2022-04-19 |
Incyte Corporation |
3-(5-amino-pyrazin-2-yl)-benzenesulfonamide derivatives and related compounds as PI3K-gamma kinase inhibitors
|
TWI797242B
(zh)
|
2018-01-30 |
2023-04-01 |
美商英塞特公司 |
製備jak抑制劑之方法及中間物
|
AU2019221667A1
(en)
|
2018-02-16 |
2020-10-01 |
Incyte Corporation |
JAK1 pathway inhibitors for the treatment of cytokine-related disorders
|
AU2019227607C1
(en)
|
2018-02-27 |
2023-07-20 |
Incyte Corporation |
Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors
|
JP7268049B2
(ja)
|
2018-03-08 |
2023-05-02 |
インサイト・コーポレイション |
PI3K-γ阻害剤としてのアミノピラジンジオール化合物
|
MX2022012285A
(es)
|
2018-03-30 |
2023-08-15 |
Incyte Corp |
Tratamiento de la hidradenitis supurativa mediante el uso de inhibidores de actividad de la cinasa janus (jak).
|
US11220510B2
(en)
|
2018-04-09 |
2022-01-11 |
Incyte Corporation |
Pyrrole tricyclic compounds as A2A / A2B inhibitors
|
CN108530364B
(zh)
*
|
2018-04-10 |
2020-01-21 |
江苏创诺制药有限公司 |
一种3-(4-甲基-1h-咪唑-1-基)-5-三氟甲基苯胺单盐酸盐的晶型及其应用
|
MA52493A
(fr)
|
2018-05-04 |
2021-03-10 |
Incyte Corp |
Sels d'un inhibiteur de fgfr
|
US11466004B2
(en)
|
2018-05-04 |
2022-10-11 |
Incyte Corporation |
Solid forms of an FGFR inhibitor and processes for preparing the same
|
JP7391046B2
(ja)
|
2018-05-18 |
2023-12-04 |
インサイト・コーポレイション |
A2a/a2b阻害剤としての縮合ピリミジン誘導体
|
ES2929415T3
(es)
|
2018-05-25 |
2022-11-29 |
Incyte Corp |
Compuestos heterocíclicos tricíclicos como activadores de STING
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
TWI815137B
(zh)
|
2018-06-15 |
2023-09-11 |
漢達生技醫藥股份有限公司 |
尼洛替尼十二烷基硫酸鹽之結晶
|
JP2020002108A
(ja)
*
|
2018-06-29 |
2020-01-09 |
住友化学株式会社 |
安息香酸化合物の製造方法
|
US11046658B2
(en)
|
2018-07-02 |
2021-06-29 |
Incyte Corporation |
Aminopyrazine derivatives as PI3K-γ inhibitors
|
JP2020007240A
(ja)
*
|
2018-07-04 |
2020-01-16 |
住友化学株式会社 |
ベンズアミド化合物の製造方法
|
CN117304191A
(zh)
|
2018-07-05 |
2023-12-29 |
因赛特公司 |
作为a2a/a2b抑制剂的稠合吡嗪衍生物
|
EP3823624A1
(en)
|
2018-07-17 |
2021-05-26 |
Boehringer Ingelheim International GmbH |
Cardiosafe antidiabetic therapy
|
JP2021530508A
(ja)
|
2018-07-17 |
2021-11-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
心臓および腎臓に安全な抗糖尿病療法
|
WO2020028565A1
(en)
|
2018-07-31 |
2020-02-06 |
Incyte Corporation |
Tricyclic heteraryl compounds as sting activators
|
WO2020028566A1
(en)
|
2018-07-31 |
2020-02-06 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|
MA53561A
(fr)
|
2018-09-05 |
2022-05-11 |
Incyte Corp |
Formes cristallines d'un inhibiteur de phosphoinositide 3-kinase (pi3k)
|
US11066404B2
(en)
|
2018-10-11 |
2021-07-20 |
Incyte Corporation |
Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
|
WO2020102150A1
(en)
|
2018-11-13 |
2020-05-22 |
Incyte Corporation |
Heterocyclic derivatives as pi3k inhibitors
|
WO2020102216A1
(en)
|
2018-11-13 |
2020-05-22 |
Incyte Corporation |
Substituted heterocyclic derivatives as pi3k inhibitors
|
WO2020102198A1
(en)
|
2018-11-13 |
2020-05-22 |
Incyte Corporation |
Heterocyclic derivatives as pi3k inhibitors
|
US11596692B1
(en)
|
2018-11-21 |
2023-03-07 |
Incyte Corporation |
PD-L1/STING conjugates and methods of use
|
US20220040324A1
(en)
|
2018-12-21 |
2022-02-10 |
Daiichi Sankyo Company, Limited |
Combination of antibody-drug conjugate and kinase inhibitor
|
WO2020146237A1
(en)
|
2019-01-07 |
2020-07-16 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
MA54947A
(fr)
|
2019-02-15 |
2021-12-22 |
Incyte Corp |
Biomarqueurs de kinase 2 dépendant de la cycline et leurs utilisations
|
US11384083B2
(en)
|
2019-02-15 |
2022-07-12 |
Incyte Corporation |
Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
|
WO2020180959A1
(en)
|
2019-03-05 |
2020-09-10 |
Incyte Corporation |
Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
WO2020205560A1
(en)
|
2019-03-29 |
2020-10-08 |
Incyte Corporation |
Sulfonylamide compounds as cdk2 inhibitors
|
WO2020223558A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
Tricyclic amine compounds as cdk2 inhibitors
|
WO2020223469A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
|
EP3982971A4
(en)
|
2019-06-10 |
2023-08-16 |
Incyte Corporation |
TOPICAL TREATMENT OF VITILIGO BY A JAK INHIBITOR
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
JP2022543062A
(ja)
|
2019-08-01 |
2022-10-07 |
インサイト・コーポレイション |
Ido阻害剤の投与レジメン
|
EP4013750A1
(en)
|
2019-08-14 |
2022-06-22 |
Incyte Corporation |
Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors
|
PE20230372A1
(es)
|
2019-08-26 |
2023-03-06 |
Incyte Corp |
Triazolopirimidinas como inhibidores de a2a/a2b
|
EP4031578A1
(en)
|
2019-09-18 |
2022-07-27 |
Novartis AG |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
WO2021072232A1
(en)
|
2019-10-11 |
2021-04-15 |
Incyte Corporation |
Bicyclic amines as cdk2 inhibitors
|
SG10201909596RA
(en)
*
|
2019-10-14 |
2021-05-28 |
Esco Aster Pte Ltd |
Synthesis of Tyrosine Kinase Inhibitors
|
CA3157361A1
(en)
|
2019-10-14 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
JP2023506118A
(ja)
|
2019-10-16 |
2023-02-15 |
インサイト・コーポレイション |
皮膚エリテマトーデス及び扁平苔癬(lp)の治療のためのjak1阻害剤の使用
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
US11992490B2
(en)
|
2019-10-16 |
2024-05-28 |
Incyte Corporation |
Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)
|
BR112022010664A2
(pt)
|
2019-12-04 |
2022-08-16 |
Incyte Corp |
Derivados de um inibidor de fgfr
|
JP2023505258A
(ja)
|
2019-12-04 |
2023-02-08 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式複素環
|
AU2021212258A1
(en)
|
2020-01-31 |
2022-09-29 |
Nanocopoeia, Llc |
Amorphous nilotinib microparticles and uses thereof
|
US20230075170A1
(en)
|
2020-02-15 |
2023-03-09 |
Cipla Limited |
Novel salts of nilotinib and polymorphic forms thereof
|
CA3174539A1
(en)
|
2020-03-06 |
2021-09-10 |
Incyte Corporation |
Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors
|
CR20220584A
(es)
|
2020-04-16 |
2023-02-15 |
Incyte Corp |
Inhibidores de kras tricíclicos fusionados
|
EP3904342A1
(en)
|
2020-04-28 |
2021-11-03 |
Grindeks, A Joint Stock Company |
Process for the preparation of 3-(trifluoromethyl)-5-(4-methyl-1h-imidazole-1-yl)-benzeneamine hydrochloride
|
EP4142699A1
(en)
|
2020-04-30 |
2023-03-08 |
Nanocopoeia LLC |
Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib
|
WO2021231526A1
(en)
|
2020-05-13 |
2021-11-18 |
Incyte Corporation |
Fused pyrimidine compounds as kras inhibitors
|
WO2021228983A1
(en)
|
2020-05-13 |
2021-11-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A pharmaceutical composition comprising an arsenic compound, an inductor of type-1 ifn and a protein kinase inhibitor for treating cancer
|
BR112022024632A2
(pt)
|
2020-06-02 |
2023-02-28 |
Incyte Corp |
Processos para preparar um inibidor de jak1
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
WO2022019998A1
(en)
|
2020-07-20 |
2022-01-27 |
Arog Pharmaceuticals, Inc. |
Crystal forms of crenolanib and methods of use thereof
|
WO2022047093A1
(en)
|
2020-08-28 |
2022-03-03 |
Incyte Corporation |
Vinyl imidazole compounds as inhibitors of kras
|
US20230364095A1
(en)
|
2020-09-16 |
2023-11-16 |
Incyte Corporation |
Topical treatment of vitiligo
|
US11767320B2
(en)
|
2020-10-02 |
2023-09-26 |
Incyte Corporation |
Bicyclic dione compounds as inhibitors of KRAS
|
US11969420B2
(en)
|
2020-10-30 |
2024-04-30 |
Arog Pharmaceuticals, Inc. |
Combination therapy of crenolanib and apoptosis pathway agents for the treatment of proliferative disorders
|
TW202237089A
(zh)
|
2020-12-08 |
2022-10-01 |
美商英塞特公司 |
用於治療白斑病之jak1途徑抑制劑
|
CN112745300A
(zh)
*
|
2021-01-21 |
2021-05-04 |
杭州浙中医药科技有限公司 |
一种制备n-(5-羧基-2-甲基苯基)-4-(3-吡啶)-2-嘧啶胺的方法
|
WO2022155941A1
(en)
|
2021-01-25 |
2022-07-28 |
Qilu Regor Therapeutics Inc. |
Cdk2 inhibitors
|
WO2022206888A1
(en)
|
2021-03-31 |
2022-10-06 |
Qilu Regor Therapeutics Inc. |
Cdk2 inhibitors and use thereof
|
WO2022221170A1
(en)
|
2021-04-12 |
2022-10-20 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
EP4352059A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
EP4352060A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
US11981671B2
(en)
|
2021-06-21 |
2024-05-14 |
Incyte Corporation |
Bicyclic pyrazolyl amines as CDK2 inhibitors
|
IL309642A
(en)
|
2021-07-07 |
2024-02-01 |
Incyte Corp |
Tricyclic compounds as inhibitors of Kras
|
WO2023287896A1
(en)
|
2021-07-14 |
2023-01-19 |
Incyte Corporation |
Tricyclic compounds as inhibitors of kras
|
WO2023034290A1
(en)
|
2021-08-31 |
2023-03-09 |
Incyte Corporation |
Naphthyridine compounds as inhibitors of kras
|
CN113717152B
(zh)
*
|
2021-09-08 |
2022-06-17 |
上海皓鸿生物医药科技有限公司 |
一种特异性mrk小分子抑制剂的制备方法
|
US20230151005A1
(en)
|
2021-09-21 |
2023-05-18 |
Incyte Corporation |
Hetero-tricyclic compounds as inhibitors of kras
|
CA3234375A1
(en)
|
2021-10-01 |
2023-04-06 |
Incyte Corporation |
Pyrazoloquinoline kras inhibitors
|
US11939328B2
(en)
|
2021-10-14 |
2024-03-26 |
Incyte Corporation |
Quinoline compounds as inhibitors of KRAS
|
WO2023081923A1
(en)
|
2021-11-08 |
2023-05-11 |
Frequency Therapeutics, Inc. |
Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof
|
TW202320792A
(zh)
|
2021-11-22 |
2023-06-01 |
美商英塞特公司 |
包含fgfr抑制劑及kras抑制劑之組合療法
|
WO2023102184A1
(en)
|
2021-12-03 |
2023-06-08 |
Incyte Corporation |
Bicyclic amine compounds as cdk12 inhibitors
|
WO2023107705A1
(en)
|
2021-12-10 |
2023-06-15 |
Incyte Corporation |
Bicyclic amines as cdk12 inhibitors
|
US11976073B2
(en)
|
2021-12-10 |
2024-05-07 |
Incyte Corporation |
Bicyclic amines as CDK2 inhibitors
|
AR128043A1
(es)
|
2021-12-22 |
2024-03-20 |
Incyte Corp |
Sales y formas sólidas de un inhibidor de fgfr y procesos para su preparación
|
TW202341982A
(zh)
|
2021-12-24 |
2023-11-01 |
大陸商上海齊魯銳格醫藥研發有限公司 |
Cdk2抑制劑及其用途
|
WO2023168686A1
(en)
|
2022-03-11 |
2023-09-14 |
Qilu Regor Therapeutics Inc. |
Substituted cyclopentanes as cdk2 inhibitors
|
TW202342023A
(zh)
|
2022-03-07 |
2023-11-01 |
美商英塞特公司 |
Cdk2抑制劑之固體形式、鹽及製備方法
|
EP4260848A1
(en)
|
2022-04-11 |
2023-10-18 |
Lotus Pharmaceutical Co., Ltd. |
Pharmaceutical composition for solid dosage form containing nilotinib and process for its preparation
|
US20230399331A1
(en)
|
2022-06-14 |
2023-12-14 |
Incyte Corporation |
Solid forms of jak inhibitor and process of preparing the same
|
WO2023250430A1
(en)
|
2022-06-22 |
2023-12-28 |
Incyte Corporation |
Bicyclic amine cdk12 inhibitors
|
WO2024015731A1
(en)
|
2022-07-11 |
2024-01-18 |
Incyte Corporation |
Fused tricyclic compounds as inhibitors of kras g12v mutants
|
WO2024030600A1
(en)
|
2022-08-05 |
2024-02-08 |
Incyte Corporation |
Treatment of urticaria using jak inhibitors
|