US2985589A
(en)
|
1957-05-22 |
1961-05-23 |
Universal Oil Prod Co |
Continuous sorption process employing fixed bed of sorbent and moving inlets and outlets
|
US3632836A
(en)
|
1968-10-25 |
1972-01-04 |
Dow Chemical Co |
Solid curable polyepoxides modified with hydrolyzed liquid polyepoxides
|
US3832460A
(en)
|
1971-03-19 |
1974-08-27 |
C Kosti |
Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
|
US4140755A
(en)
|
1976-02-13 |
1979-02-20 |
Hoffmann-La Roche Inc. |
Sustained release tablet formulations
|
DE3036390A1
(de)
|
1980-09-26 |
1982-05-13 |
Troponwerke GmbH & Co KG, 5000 Köln |
Neue pyrrolo-pyrimidine, verfahren zu ihrer herstellung und ihre verwendung bei der herstellung von biologischen wirkstoffen
|
DE3220113A1
(de)
|
1982-05-28 |
1983-12-01 |
Basf Ag, 6700 Ludwigshafen |
Difluormethoxiphenylthiophosphorsaeureester
|
US4402832A
(en)
|
1982-08-12 |
1983-09-06 |
Uop Inc. |
High efficiency continuous separation process
|
US4404335A
(en)
|
1982-08-16 |
1983-09-13 |
The Dow Chemical Company |
Hydrolyzing epoxy resins in absence of solvent and in presence of oxalic acid and a phosphonium compound
|
US4548990A
(en)
|
1983-08-15 |
1985-10-22 |
Ciba-Geigy Corporation |
Crosslinked, porous polymers for controlled drug delivery
|
US4498991A
(en)
|
1984-06-18 |
1985-02-12 |
Uop Inc. |
Serial flow continuous separation process
|
NL8403224A
(nl)
|
1984-10-24 |
1986-05-16 |
Oce Andeno Bv |
Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen.
|
CA1306260C
(en)
|
1985-10-18 |
1992-08-11 |
Shionogi & Co., Ltd. |
Condensed imidazopyridine derivatives
|
US4921947A
(en)
|
1986-03-31 |
1990-05-01 |
Eli Lilly And Company |
Process for preparing macrolide derivatives
|
WO1991005784A1
(fr)
|
1989-10-11 |
1991-05-02 |
Teijin Limited |
Derive de pyrimidine bicyclique, procede de production et preparation pharmaceutique le contenant en tant qu'ingredient actif
|
US5403593A
(en)
|
1991-03-04 |
1995-04-04 |
Sandoz Ltd. |
Melt granulated compositions for preparing sustained release dosage forms
|
IT1258781B
(it)
|
1992-01-16 |
1996-02-29 |
Zambon Spa |
Composizione farmaceutica oftalmica contenente n-acetilcisteina e polivinilalcol
|
US5521184A
(en)
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
FR2695126B1
(fr)
|
1992-08-27 |
1994-11-10 |
Sanofi Elf |
Dérivés d'acide thiényl ou pyrrolyl carboxyliques, leur préparation et médicaments les contenant.
|
AU671491B2
(en)
|
1992-12-18 |
1996-08-29 |
F. Hoffmann-La Roche Ag |
N-oxycarbonyl substituted 5'-deoxy-5-fluorcytidines
|
JPH0710876A
(ja)
|
1993-06-24 |
1995-01-13 |
Teijin Ltd |
4位に環状アミノ基を有するピロロ[2,3―d]ピリミジン
|
USH1439H
(en)
|
1993-10-18 |
1995-05-02 |
The Dow Chemical Company |
Method to increase the level of α-glycol in liquid epoxy resin
|
EP0727217A3
(en)
|
1995-02-10 |
1997-01-15 |
Suntory Ltd |
Pharmaceutical and cosmetic compositions containing God-type ellagitannin as an active ingredient
|
US5856326A
(en)
|
1995-03-29 |
1999-01-05 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
IL117580A0
(en)
|
1995-03-29 |
1996-07-23 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
|
KR19990028709A
(ko)
|
1995-07-05 |
1999-04-15 |
미리암 디. 메코너헤이 |
살진균 피리미디논
|
BR9609617B1
(pt)
|
1995-07-06 |
2010-07-27 |
|
derivados de 7h-pirrol[2,3-d]pirimidina, e composição farmacêutica.
|
US5630943A
(en)
|
1995-11-30 |
1997-05-20 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
Discontinuous countercurrent chromatographic process and apparatus
|
GB9604361D0
(en)
|
1996-02-29 |
1996-05-01 |
Pharmacia Spa |
4-Substituted pyrrolopyrimidine compounds as tyrosine kinase inhibitors
|
WO1997036587A1
(en)
|
1996-04-03 |
1997-10-09 |
Merck & Co., Inc. |
A method of treating cancer
|
CA2251955A1
(en)
|
1996-04-18 |
1997-10-23 |
Nancy E. Kohl |
A method of treating cancer
|
US5795909A
(en)
|
1996-05-22 |
1998-08-18 |
Neuromedica, Inc. |
DHA-pharmaceutical agent conjugates of taxanes
|
EP0934270A1
(en)
|
1996-05-30 |
1999-08-11 |
Merck & Co., Inc. |
A method of treating cancer
|
US6624138B1
(en)
|
2001-09-27 |
2003-09-23 |
Gp Medical |
Drug-loaded biological material chemically treated with genipin
|
WO1998044797A1
(en)
|
1997-04-07 |
1998-10-15 |
Merck & Co., Inc. |
A method of treating cancer
|
US6063284A
(en)
|
1997-05-15 |
2000-05-16 |
Em Industries, Inc. |
Single column closed-loop recycling with periodic intra-profile injection
|
US6060038A
(en)
|
1997-05-15 |
2000-05-09 |
Merck & Co., Inc. |
Radiolabeled farnesyl-protein transferase inhibitors
|
US5919779A
(en)
|
1997-08-11 |
1999-07-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
5,6-Heteroaryl-dipyrido(2,3-B:3', 2'-F) azepines and their use in the prevention or treatment of HIV infection
|
US7153845B2
(en)
|
1998-08-25 |
2006-12-26 |
Columbia Laboratories, Inc. |
Bioadhesive progressive hydration tablets
|
US6075056A
(en)
|
1997-10-03 |
2000-06-13 |
Penederm, Inc. |
Antifungal/steroid topical compositions
|
US6025366A
(en)
|
1998-04-02 |
2000-02-15 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
WO1999062908A2
(en)
|
1998-06-04 |
1999-12-09 |
Abbott Laboratories |
Cell adhesion-inhibiting antinflammatory compounds
|
US6232320B1
(en)
|
1998-06-04 |
2001-05-15 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
RS50087B
(sr)
|
1998-06-19 |
2009-01-22 |
Pfizer Products Inc., |
Pirolo (2,3-d) pirimidin jedinjenja
|
PA8474101A1
(es)
|
1998-06-19 |
2000-09-29 |
Pfizer Prod Inc |
Compuestos de pirrolo [2,3-d] pirimidina
|
ES2342240T3
(es)
|
1998-08-11 |
2010-07-02 |
Novartis Ag |
Derivados de isoquinolina con actividad que inhibe la angiogenia.
|
JP2000119271A
(ja)
|
1998-08-12 |
2000-04-25 |
Hokuriku Seiyaku Co Ltd |
1h―イミダゾピリジン誘導体
|
EA004032B1
(ru)
|
1998-09-10 |
2003-12-25 |
Нюкомед Данмарк А/С |
Фармацевтические композиции лекарственных веществ с быстрым высвобождением
|
FR2785196B1
(fr)
|
1998-10-29 |
2000-12-15 |
Inst Francais Du Petrole |
Procede et dispositif de separation avec des zones chromatographiques a longueur variable
|
US6375839B1
(en)
|
1998-10-29 |
2002-04-23 |
Institut Francais Du Petrole |
Process and device for separation with variable-length chromatographic zones
|
US6413419B1
(en)
|
1998-10-29 |
2002-07-02 |
Institut Francais Du Petrole |
Process and device for separation with variable-length chromatographic
|
US6133031A
(en)
|
1999-08-19 |
2000-10-17 |
Isis Pharmaceuticals Inc. |
Antisense inhibition of focal adhesion kinase expression
|
WO2000051614A1
(en)
|
1999-03-03 |
2000-09-08 |
Merck & Co., Inc. |
Inhibitors of prenyl-protein transferases
|
GB9905075D0
(en)
|
1999-03-06 |
1999-04-28 |
Zeneca Ltd |
Chemical compounds
|
US6217895B1
(en)
|
1999-03-22 |
2001-04-17 |
Control Delivery Systems |
Method for treating and/or preventing retinal diseases with sustained release corticosteroids
|
US6239113B1
(en)
|
1999-03-31 |
2001-05-29 |
Insite Vision, Incorporated |
Topical treatment or prevention of ocular infections
|
AU3565999A
(en)
|
1999-04-16 |
2000-11-02 |
Coelacanth Chemical Corporation |
Synthesis of azetidine derivatives
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
DE60013464T2
(de)
|
1999-10-13 |
2005-09-15 |
Banyu Pharmaceutical Co., Ltd. |
Substituierte imidazolin-derivate
|
US7235258B1
(en)
|
1999-10-19 |
2007-06-26 |
Nps Pharmaceuticals, Inc. |
Sustained-release formulations for treating CNS-mediated disorders
|
PT1382339E
(pt)
|
1999-12-10 |
2008-02-06 |
Pfizer Prod Inc |
Composições que contêm derivados de pirrolo[2,3-d]- pirimidina
|
MXPA02006338A
(es)
|
1999-12-24 |
2002-12-13 |
Aventis Pharma Ltd |
Azaindoles.
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
US7235551B2
(en)
|
2000-03-02 |
2007-06-26 |
Smithkline Beecham Corporation |
1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
|
DE60100866T2
(de)
|
2000-04-07 |
2004-07-29 |
Laboratoire Medidom S.A. |
Cyklosporin, Hyaluronsäure und Polysorbate enthaltenes Augenarzneimittel
|
WO2001081345A1
(fr)
|
2000-04-20 |
2001-11-01 |
Mitsubishi Pharma Corporation |
Composes d'amides aromatiques
|
ES2788383T3
(es)
|
2000-04-25 |
2020-10-21 |
Icos Corp |
Inhibidores de delta fosfatidilo-inositol 3-quinasa humana
|
IL153115A0
(en)
|
2000-06-16 |
2003-06-24 |
Curis Inc |
Angiogenesis-modulating compositions and uses
|
US7498304B2
(en)
|
2000-06-16 |
2009-03-03 |
Curis, Inc. |
Angiogenesis-modulating compositions and uses
|
US6335342B1
(en)
|
2000-06-19 |
2002-01-01 |
Pharmacia & Upjohn S.P.A. |
Azaindole derivatives, process for their preparation, and their use as antitumor agents
|
EP1295607B9
(en)
|
2000-06-23 |
2011-10-05 |
Mitsubishi Tanabe Pharma Corporation |
Antitumor effect potentiators
|
OA12292A
(en)
|
2000-06-26 |
2003-11-11 |
Pfizer Prod Inc |
PyrroloÄ2,3-dÜpyrimidine compounds as immunosuppressive agents.
|
SI1294358T1
(en)
|
2000-06-28 |
2004-12-31 |
Smithkline Beecham Plc |
Wet milling process
|
AU2001278790A1
(en)
|
2000-08-22 |
2002-03-04 |
Hokuriku Seiyaku Co. Ltd |
1h-imidazopyridine derivatives
|
CA2430539C
(en)
|
2000-12-05 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases
|
GB0100622D0
(en)
|
2001-01-10 |
2001-02-21 |
Vernalis Res Ltd |
Chemical compounds V111
|
JP2004520347A
(ja)
|
2001-01-15 |
2004-07-08 |
グラクソ グループ リミテッド |
Ldl−受容体発現のインデューサーとしてのアリールピペリジンおよびピペラジン誘導体
|
CA2436487A1
(en)
|
2001-01-30 |
2002-08-08 |
Cytopia Pty Ltd. |
Methods of inhibiting kinases
|
JP4316893B2
(ja)
|
2001-05-16 |
2009-08-19 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Srcおよび他のプロテインキナーゼのインヒビター
|
US7301023B2
(en)
|
2001-05-31 |
2007-11-27 |
Pfizer Inc. |
Chiral salt resolution
|
GB0115109D0
(en)
|
2001-06-21 |
2001-08-15 |
Aventis Pharma Ltd |
Chemical compounds
|
GB0115393D0
(en)
|
2001-06-23 |
2001-08-15 |
Aventis Pharma Ltd |
Chemical compounds
|
AU2002355732B2
(en)
|
2001-08-01 |
2006-11-09 |
Merck Sharp & Dohme Corp. |
Benzimidazo[4,5-f]isoquinolinone derivatives
|
HUP0401982A3
(en)
|
2001-09-19 |
2012-09-28 |
Aventis Pharma Sa |
Indolizine derivates, process for their preparation and pharmaceutical compositions containing the compounds
|
US6429231B1
(en)
|
2001-09-24 |
2002-08-06 |
Bradley Pharmaceuticals, Inc. |
Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use
|
PT1441737E
(pt)
|
2001-10-30 |
2006-12-29 |
Dana Farber Cancer Inst Inc |
Derivados de estrutura como inibidores da actividade do receptor de tirosina cinase flt3
|
JP2003155285A
(ja)
|
2001-11-19 |
2003-05-27 |
Toray Ind Inc |
環状含窒素誘導体
|
KR20040058340A
(ko)
|
2001-11-30 |
2004-07-03 |
데이진 가부시키가이샤 |
5-(3-시아노페닐)-3-포르밀벤조산 화합물의 제조 방법
|
GT200200234A
(es)
|
2001-12-06 |
2003-06-27 |
|
Compuestos cristalinos novedosos
|
US6995144B2
(en)
|
2002-03-14 |
2006-02-07 |
Eisai Co., Ltd. |
Nitrogen containing heterocyclic compounds and medicines containing the same
|
EA007156B1
(ru)
|
2002-04-15 |
2006-08-25 |
Адамс Лэборетриз, Инк. |
Замедленно высвобождающие лекарственные композиции гвайфенезина
|
TW200403058A
(en)
|
2002-04-19 |
2004-03-01 |
Bristol Myers Squibb Co |
Heterocyclo inhibitors of potassium channel function
|
EP1506189A1
(en)
|
2002-04-26 |
2005-02-16 |
Vertex Pharmaceuticals Incorporated |
Pyrrole derivatives as inhibitors of erk2 and uses thereof
|
JP2005530745A
(ja)
|
2002-05-02 |
2005-10-13 |
メルク エンド カムパニー インコーポレーテッド |
チロシンキナーゼ阻害剤
|
MXPA04011004A
(es)
|
2002-05-07 |
2005-01-25 |
Control Delivery Sys Inc |
Procesos para formar un dispositivo de administracion de farmaco.
|
DE60317198T2
(de)
|
2002-05-23 |
2008-12-04 |
Cytopia Research Pty. Ltd., Richmond |
Proteinkinaseinhibitoren
|
TW200406374A
(en)
|
2002-05-29 |
2004-05-01 |
Novartis Ag |
Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
|
CA2490340A1
(en)
|
2002-06-26 |
2004-01-08 |
Idemitsu Kosan Co., Ltd. |
Hydrogenated copolymer, production process for the same and hot melt adhesive composition using the same
|
GB0215676D0
(en)
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
GB0215844D0
(en)
|
2002-07-09 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
WO2004007472A1
(ja)
|
2002-07-10 |
2004-01-22 |
Ono Pharmaceutical Co., Ltd. |
Ccr4アンタゴニストおよびその医薬用途
|
KR20050057175A
(ko)
|
2002-09-20 |
2005-06-16 |
알콘, 인코퍼레이티드 |
안구건조증 치료용 사이토카인 합성 저해제의 용도
|
US20040204404A1
(en)
|
2002-09-30 |
2004-10-14 |
Robert Zelle |
Human N-type calcium channel blockers
|
JP4688498B2
(ja)
|
2002-11-04 |
2011-05-25 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Jakインヒビターとしてのヘテロアリール−ピリミジン誘導体
|
US8034831B2
(en)
|
2002-11-06 |
2011-10-11 |
Celgene Corporation |
Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
|
CL2003002353A1
(es)
|
2002-11-15 |
2005-02-04 |
Vertex Pharma |
Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic
|
US20040099204A1
(en)
|
2002-11-25 |
2004-05-27 |
Nestor John J. |
Sheet, page, line, position marker
|
KR20050086784A
(ko)
|
2002-11-26 |
2005-08-30 |
화이자 프로덕츠 인크. |
이식 거부반응의 치료 방법
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
TWI335819B
(en)
|
2002-12-24 |
2011-01-11 |
Alcon Inc |
Use of oculosurface selective glucocorticoid in the treatment of dry eye
|
US7135493B2
(en)
|
2003-01-13 |
2006-11-14 |
Astellas Pharma Inc. |
HDAC inhibitor
|
US7444183B2
(en)
|
2003-02-03 |
2008-10-28 |
Enteromedics, Inc. |
Intraluminal electrode apparatus and method
|
CA2515132C
(en)
|
2003-02-07 |
2012-01-03 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl substituted pyrroles useful as inhibitors of protein kinases
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
EP1615906A1
(en)
|
2003-04-03 |
2006-01-18 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of protein kinases
|
SE0301373D0
(sv)
|
2003-05-09 |
2003-05-09 |
Astrazeneca Ab |
Novel compounds
|
SE0301372D0
(sv)
|
2003-05-09 |
2003-05-09 |
Astrazeneca Ab |
Novel compounds
|
FR2857454B1
(fr)
|
2003-07-08 |
2006-08-11 |
Aventis Pasteur |
Dosage des acides techoiques des bacteries gram+
|
US20050043346A1
(en)
|
2003-08-08 |
2005-02-24 |
Pharmacia Italia S.P.A. |
Pyridylpyrrole derivatives active as kinase inhibitors
|
AU2004268621C1
(en)
|
2003-08-29 |
2011-08-18 |
Exelixis, Inc. |
c-Kit modulators and methods of use
|
EP1678147B1
(en)
|
2003-09-15 |
2012-08-08 |
Lead Discovery Center GmbH |
Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases
|
PE20050952A1
(es)
|
2003-09-24 |
2005-12-19 |
Novartis Ag |
Derivados de isoquinolina como inhibidores de b-raf
|
KR101154175B1
(ko)
|
2003-10-24 |
2012-06-14 |
산텐 세이야꾸 가부시키가이샤 |
각결막 장해 치료제
|
US7387793B2
(en)
|
2003-11-14 |
2008-06-17 |
Eurand, Inc. |
Modified release dosage forms of skeletal muscle relaxants
|
MY141220A
(en)
|
2003-11-17 |
2010-03-31 |
Astrazeneca Ab |
Pyrazole derivatives as inhibitors of receptor tyrosine kinases
|
JP2007512316A
(ja)
|
2003-11-25 |
2007-05-17 |
ファイザー・プロダクツ・インク |
アテローム性動脈硬化症の治療方法
|
BRPI0417803A
(pt)
|
2003-12-17 |
2007-04-10 |
Pfizer Prod Inc |
método de tratamento de rejeição de transplantes
|
CN1918138B
(zh)
|
2003-12-19 |
2011-05-04 |
先灵公司 |
作为cxc-和cc-趋化因子受体配体的噻二唑化合物
|
PL1696920T3
(pl)
|
2003-12-19 |
2015-03-31 |
Plexxikon Inc |
Związki i sposoby opracowywania modulatorów Ret
|
US8247576B2
(en)
|
2003-12-23 |
2012-08-21 |
Astex Therapeutics Limited |
Pyrazole derivatives as protein kinase modulators
|
US20050239806A1
(en)
|
2004-01-13 |
2005-10-27 |
Ambit Biosciences Corporation |
Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
|
WO2005089502A2
(en)
|
2004-03-18 |
2005-09-29 |
The Brigham And Women's Hospital, Inc. |
Methods for the treatment of synucleinopathies
|
MXPA06011327A
(es)
|
2004-03-30 |
2006-12-15 |
Vertex Pharma |
Azaindoles utiles como inhibidores de jak y otras proteinas cinasas.
|
CA2563699C
(en)
|
2004-04-23 |
2014-03-25 |
Exelixis, Inc. |
Kinase modulators and method of use
|
US20060106020A1
(en)
|
2004-04-28 |
2006-05-18 |
Rodgers James D |
Tetracyclic inhibitors of Janus kinases
|
US7558717B2
(en)
|
2004-04-28 |
2009-07-07 |
Vertex Pharmaceuticals Incorporated |
Crystal structure of human JAK3 kinase domain complex and binding pockets thereof
|
EP1755680A1
(en)
|
2004-05-03 |
2007-02-28 |
Novartis AG |
Combinations comprising a s1p receptor agonist and a jak3 kinase inhibitor
|
MXPA06013250A
(es)
|
2004-05-14 |
2007-02-28 |
Abbott Lab |
Inhibidores de quinasa como agentes terapeuticos.
|
PE20060426A1
(es)
|
2004-06-02 |
2006-06-28 |
Schering Corp |
DERIVADOS DE ACIDO TARTARICO COMO INHIBIDORES DE MMPs, ADAMs, TACE Y TNF-alfa
|
US7745437B2
(en)
|
2004-06-10 |
2010-06-29 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
EP1760071A4
(en)
|
2004-06-23 |
2008-03-05 |
Ono Pharmaceutical Co |
COMPOUND WITH S1P RECEPTOR BINDING ABILITY AND USE THEREOF
|
CA2572058A1
(en)
|
2004-06-30 |
2006-01-12 |
Vertex Pharmaceuticals Incorporated |
Azaindoles useful as inhibitors of protein kinases
|
US7138423B2
(en)
|
2004-07-20 |
2006-11-21 |
Bristol-Myers Squibb Company |
Arylpyrrolidine derivatives as NK-1 /SSRI antagonists
|
FR2873691B1
(fr)
|
2004-07-29 |
2006-10-06 |
Sanofi Synthelabo |
Derives d'amino-piperidine, leur preparation et leur application en therapeutique
|
WO2006013114A1
(en)
|
2004-08-06 |
2006-02-09 |
Develogen Aktiengesellschaft |
Use of a timp-2 secreted protein product for preventing and treating pancreatic diseases and/or obesity and/or metabolic syndrome
|
WO2006022459A1
(en)
|
2004-08-23 |
2006-03-02 |
Mogam Biotechnology Institute |
Primer and probe for detection of sars coronavirus, kit comprising the primer and/or the probe, and detection method thereof
|
US20070054916A1
(en)
|
2004-10-01 |
2007-03-08 |
Amgen Inc. |
Aryl nitrogen-containing bicyclic compounds and methods of use
|
CN101039946B
(zh)
|
2004-10-13 |
2010-12-08 |
霍夫曼-拉罗奇有限公司 |
用作用于cdk2和血管生成的抑制剂及用于治疗乳腺、结肠、肺和前列腺癌的二取代吡唑并苯并二氮杂*类
|
MY179032A
(en)
|
2004-10-25 |
2020-10-26 |
Cancer Research Tech Ltd |
Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
|
UY29177A1
(es)
|
2004-10-25 |
2006-05-31 |
Astex Therapeutics Ltd |
Derivados sustituidos de purina, purinona y deazapurina, composiciones que los contienen métodos para su preparación y sus usos
|
AU2005304784B2
(en)
|
2004-11-04 |
2011-03-24 |
Vertex Pharmaceuticals Incorporated |
Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases
|
CA2586605A1
(en)
|
2004-11-24 |
2006-06-01 |
Novartis Ag |
Combinations of jak inhibitors and at least one of bcr-abl, flt-3, fak or raf kinase inhibitors
|
US7517870B2
(en)
|
2004-12-03 |
2009-04-14 |
Fondazione Telethon |
Use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization
|
US20060128803A1
(en)
|
2004-12-14 |
2006-06-15 |
Alcon, Inc. |
Method of treating dry eye disorders using 13(S)-HODE and its analogs
|
WO2006067445A2
(en)
|
2004-12-22 |
2006-06-29 |
Astrazeneca Ab |
Csf-1r kinase inhibitors
|
AR054416A1
(es)
|
2004-12-22 |
2007-06-27 |
Incyte Corp |
Pirrolo [2,3-b]piridin-4-il-aminas y pirrolo [2,3-b]pirimidin-4-il-aminas como inhibidores de las quinasas janus. composiciones farmaceuticas.
|
JP2008528477A
(ja)
|
2005-01-20 |
2008-07-31 |
ファイザー・リミテッド |
化合物
|
WO2006096270A1
(en)
|
2005-02-03 |
2006-09-14 |
Vertex Pharmaceuticals Incorporated |
Pyrrolopyrimidines useful as inhibitors of protein kinase
|
US7683171B2
(en)
|
2005-02-04 |
2010-03-23 |
Bristol-Myers Squibb Company |
1H-imidazo[4,5-d]thieno[3,2-b]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
|
WO2006101783A2
(en)
|
2005-03-15 |
2006-09-28 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
BRPI0610514A2
(pt)
|
2005-04-05 |
2016-11-16 |
Pharmacopeia Inc |
composto, composição farmacêutica, e, método de tratamento de um distúrbio
|
GB0510139D0
(en)
|
2005-05-18 |
2005-06-22 |
Addex Pharmaceuticals Sa |
Novel compounds B1
|
RU2435769C2
(ru)
|
2005-05-20 |
2011-12-10 |
Вертекс Фармасьютикалз Инкорпорейтед |
Пирролопиридины, полезные в качестве ингибиторов протеинкиназы
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
NZ563454A
(en)
|
2005-06-08 |
2011-03-31 |
Rigel Pharmaceuticals Inc |
2,4-diaminopyrimidine derivatives for inhibition of the JAK pathway
|
WO2006136823A1
(en)
|
2005-06-21 |
2006-12-28 |
Astex Therapeutics Limited |
Heterocyclic containing amines as kinase b inhibitors
|
DK1893612T3
(da)
|
2005-06-22 |
2011-11-21 |
Plexxikon Inc |
Pyrrol [2,3-B]pyridin-derivater som proteinkinasehæmmere
|
CN102127078A
(zh)
|
2005-07-14 |
2011-07-20 |
安斯泰来制药株式会社 |
Janus激酶3的杂环类抑制剂
|
FR2889662B1
(fr)
|
2005-08-11 |
2011-01-14 |
Galderma Res & Dev |
Emulsion de type huile-dans-eau pour application topique en dermatologie
|
US20070049591A1
(en)
|
2005-08-25 |
2007-03-01 |
Kalypsys, Inc. |
Inhibitors of MAPK/Erk Kinase
|
US20070149506A1
(en)
|
2005-09-22 |
2007-06-28 |
Arvanitis Argyrios G |
Azepine inhibitors of Janus kinases
|
RU2008117151A
(ru)
|
2005-09-30 |
2009-11-10 |
Вертекс Фармасьютикалз Инкорпорейтед (Us) |
Деазапурины, пригодные в качестве ингибиторов янус-киназ
|
US20070128633A1
(en)
|
2005-10-11 |
2007-06-07 |
Chembridge Research Laboratories, Inc. |
Cell-free protein expression systems and methods of use thereof
|
AU2006300182B2
(en)
|
2005-10-14 |
2012-01-19 |
Sumitomo Chemical Company, Limited |
Hydrazide compound and pesticidal use of the same
|
US20080287475A1
(en)
|
2005-10-28 |
2008-11-20 |
Astrazeneca Ab |
4-(3-Aminopyrazole) Pyrimidine Derivatives for Use as Tyrosine Kinase Inhibitors in the Treatment of Cancer
|
MY167260A
(en)
|
2005-11-01 |
2018-08-14 |
Targegen Inc |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
WO2007062459A1
(en)
|
2005-11-29 |
2007-06-07 |
Cytopia Research Pty Ltd |
Selective kinase inhibitors based on pyridine scaffold
|
US20130137681A1
(en)
|
2005-12-13 |
2013-05-30 |
Incyte Corporation |
HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS
|
ES2700433T3
(es)
|
2005-12-13 |
2019-02-15 |
Incyte Holdings Corp |
Derivados de pirrolo[2,3-d]pirimidina como inhibidores de quinasas Janus
|
WO2007076423A2
(en)
|
2005-12-22 |
2007-07-05 |
Smithkline Beecham Corporation |
INHIBITORS OF Akt ACTIVITY
|
BRPI0620341A2
(pt)
|
2005-12-23 |
2011-11-08 |
Smithkline Beecham Corparation |
azaindóis inibidores de cinases aurora
|
JP4643455B2
(ja)
|
2006-01-12 |
2011-03-02 |
株式会社ユニバーサルエンターテインメント |
遊技システム
|
EP2559694A3
(en)
|
2006-01-17 |
2013-04-03 |
Vertex Pharmaceuticals, Inc. |
Azaindoles useful as inhibitors of Janus kinases
|
CA2635899A1
(en)
|
2006-01-19 |
2007-07-26 |
Osi Pharmaceuticals, Inc. |
Fused heterobicyclic kinase inhibitors
|
JP2009525350A
(ja)
|
2006-02-01 |
2009-07-09 |
スミスクライン ビーチャム コーポレーション |
Rafキナーゼ阻害薬として有用なピロロ[2,3,b]ピリジン誘導体
|
US7745477B2
(en)
|
2006-02-07 |
2010-06-29 |
Hoffman-La Roche Inc. |
Heteroaryl and benzyl amide compounds
|
US20070202172A1
(en)
|
2006-02-24 |
2007-08-30 |
Tomer Gold |
Metoprolol succinate E.R. tablets and methods for their preparation
|
US8003642B2
(en)
|
2006-03-10 |
2011-08-23 |
Ono Pharmaceutical Co., Ltd. |
Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient
|
MX2008012738A
(es)
|
2006-04-03 |
2009-02-06 |
Astellas Pharma Inc |
Heterocompuesto.
|
EP2001884A1
(en)
|
2006-04-05 |
2008-12-17 |
Vertex Pharmaceuticals, Inc. |
Deazapurines useful as inhibitors of janus kinases
|
JP2009533416A
(ja)
|
2006-04-12 |
2009-09-17 |
ファイザー・リミテッド |
ケモカインccr5受容体の調節剤としてのピロリジン誘導体
|
WO2007129195A2
(en)
|
2006-05-04 |
2007-11-15 |
Pfizer Products Inc. |
4-pyrimidine-5-amino-pyrazole compounds
|
EP2040704A2
(en)
|
2006-05-18 |
2009-04-01 |
Bayer Healthcare Ag |
Pharmaceutical compositions comprising implitapide and methods of using same
|
US7691811B2
(en)
|
2006-05-25 |
2010-04-06 |
Bodor Nicholas S |
Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
|
JO3235B1
(ar)
|
2006-05-26 |
2018-03-08 |
Astex Therapeutics Ltd |
مركبات بيررولوبيريميدين و استعمالاتها
|
NZ573174A
(en)
|
2006-06-01 |
2012-01-12 |
Msd Consumer Care Inc |
Sustained release pharmaceutical dosage form containing phenylephrine
|
JP2009544625A
(ja)
|
2006-07-20 |
2009-12-17 |
メーメット・カーラマン |
Rhoキナーゼのベンゾチオフェン阻害剤
|
WO2008013622A2
(en)
|
2006-07-27 |
2008-01-31 |
E. I. Du Pont De Nemours And Company |
Fungicidal azocyclic amides
|
WO2008016123A1
(fr)
|
2006-08-03 |
2008-02-07 |
Takeda Pharmaceutical Company Limited |
INHIBITEUR DE LA GSK-3β
|
ATE517868T1
(de)
|
2006-08-16 |
2011-08-15 |
Boehringer Ingelheim Int |
Pyrazinverbindungen, ihre verwendung und herstellungsverfahren
|
PE20080769A1
(es)
|
2006-09-08 |
2008-08-14 |
Novartis Ag |
Derivados de biaril-sulfonamida
|
WO2008035376A2
(en)
|
2006-09-19 |
2008-03-27 |
Council Of Scientific & Industrial Research |
A novel bio-erodible insert for ophthalmic applications and a process for the preparation thereof
|
TW200831104A
(en)
|
2006-10-04 |
2008-08-01 |
Pharmacopeia Inc |
6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
|
AR063141A1
(es)
|
2006-10-04 |
2008-12-30 |
Pharmacopeia Inc |
Derivados de 2- ( benzimidazolil ) purina 8- sustituida para inmunosupresion
|
US20120225057A1
(en)
|
2006-10-11 |
2012-09-06 |
Deciphera Pharmaceuticals, Llc |
Methods and compositions for the treatment of myeloproliferative diseases and other proliferative diseases
|
EP2086979B1
(en)
|
2006-11-06 |
2015-06-03 |
Tolero Pharmaceuticals, Inc. |
Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors
|
US20080119496A1
(en)
|
2006-11-16 |
2008-05-22 |
Pharmacopeia Drug Discovery, Inc. |
7-Substituted Purine Derivatives for Immunosuppression
|
WO2008064157A1
(en)
|
2006-11-22 |
2008-05-29 |
Incyte Corporation |
Imidazotriazines and imidazopyrimidines as kinase inhibitors
|
WO2008067119A2
(en)
|
2006-11-27 |
2008-06-05 |
Smithkline Beecham Corporation |
Novel compounds
|
AU2007334436A1
(en)
|
2006-12-15 |
2008-06-26 |
Abbott Laboratories |
Novel oxadiazole compounds
|
MX2009006543A
(es)
|
2006-12-20 |
2009-06-26 |
Amgen Inc |
Compuestos heterociclicos y su uso en el tratamiento de la inflamacion, angiogenesis y cancer.
|
CA2672438A1
(en)
|
2006-12-20 |
2008-07-03 |
Amgen Inc. |
Substituted heterocycles and methods of use
|
ES2415863T3
(es)
|
2006-12-22 |
2013-07-29 |
Incyte Corporation |
Heterociclos sustituidos como inhibidores de Janus Quinasas
|
WO2008077712A1
(en)
|
2006-12-22 |
2008-07-03 |
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. |
Gel useful for the delivery of ophthalmic drugs
|
WO2008082840A1
(en)
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
WO2008082839A2
(en)
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
KR20080062876A
(ko)
|
2006-12-29 |
2008-07-03 |
주식회사 대웅제약 |
신규한 항진균성 트리아졸 유도체
|
MX2009009304A
(es)
|
2007-03-01 |
2009-11-18 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso.
|
US8138181B2
(en)
|
2007-04-03 |
2012-03-20 |
Array Biopharma Inc. |
Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors
|
US8188178B2
(en)
|
2007-05-07 |
2012-05-29 |
3M Innovative Properties Company |
Cold shrinkable article including an epichlorohydrin composition
|
GB0709031D0
(en)
|
2007-05-10 |
2007-06-20 |
Sareum Ltd |
Pharmaceutical compounds
|
JP5603770B2
(ja)
|
2007-05-31 |
2014-10-08 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ccr2受容体拮抗薬およびその使用
|
GB0710528D0
(en)
|
2007-06-01 |
2007-07-11 |
Glaxo Group Ltd |
Novel compounds
|
HUE029236T2
(en)
|
2007-06-13 |
2017-02-28 |
Incyte Holdings Corp |
(R) -3- (4- (7H-Pyrrolo [2,3-d] pyrimidin-4-yl) -1H-pyrazol-1-yl) -3-cyclopentylpropanenitrile Crystalline salts of Janus kinase inhibitor
|
CL2008001709A1
(es)
|
2007-06-13 |
2008-11-03 |
Incyte Corp |
Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
|
KR101258316B1
(ko)
|
2007-07-11 |
2013-04-30 |
화이자 인코포레이티드 |
안구 건조증 치료용 약학 조성물 및 방법
|
EA201000113A1
(ru)
|
2007-08-01 |
2010-08-30 |
Пфайзер Инк. |
Пиразольные соединения
|
WO2009049028A1
(en)
|
2007-10-09 |
2009-04-16 |
Targegen Inc. |
Pyrrolopyrimidine compounds and their use as janus kinase modulators
|
CA2743756A1
(en)
|
2007-11-15 |
2009-05-22 |
Musc Foundation For Research Development |
Inhibitors of pim protein kinases, compositions, and methods for treating cancer
|
UA104849C2
(uk)
|
2007-11-16 |
2014-03-25 |
Інсайт Корпорейшн |
4-піразоліл-n-арилпіримідин-2-аміни і 4-піразоліл-n-гетероарилпіримідин-2-аміни як інгібітори кіназ janus
|
GB0723815D0
(en)
|
2007-12-05 |
2008-01-16 |
Glaxo Group Ltd |
Compounds
|
EP2231689B1
(en)
|
2008-01-18 |
2016-07-20 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
Novel cytostatic 7-deazapurine nucleosides
|
NZ587165A
(en)
|
2008-02-04 |
2012-03-30 |
Mercury Therapeutics Inc |
Ampk modulators
|
PE20091577A1
(es)
|
2008-03-03 |
2009-11-05 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso
|
DK2288610T3
(en)
|
2008-03-11 |
2016-11-28 |
Incyte Holdings Corp |
Azetidinesulfonic AND CYCLOBUTANDERIVATER AS JAK INHIBITORS
|
CA2718936A1
(en)
|
2008-03-21 |
2009-09-24 |
Novartis Ag |
Novel heterocyclic compounds and uses therof
|
AU2009260389A1
(en)
|
2008-06-18 |
2009-12-23 |
Merck Sharp & Dohme Corp. |
Inhibitors of Janus kinases
|
CN105147608B
(zh)
|
2008-06-26 |
2019-12-10 |
安特里奥公司 |
真皮递送
|
TWI461423B
(zh)
|
2008-07-02 |
2014-11-21 |
Astrazeneca Ab |
用於治療Pim激酶相關病狀及疾病之噻唑啶二酮化合物
|
FR2933409B1
(fr)
|
2008-07-03 |
2010-08-27 |
Centre Nat Rech Scient |
NOUVEAUX PYRROLO °2,3-a! CARBAZOLES ET LEUR UTILISATION COMME INHIBITEURS DES KINASES PIM
|
TWI496779B
(zh)
|
2008-08-19 |
2015-08-21 |
Array Biopharma Inc |
作為pim激酶抑制劑之三唑吡啶化合物
|
US8557809B2
(en)
|
2008-08-19 |
2013-10-15 |
Array Biopharma Inc. |
Triazolopyridine compounds as PIM kinase inhibitors
|
ME01269B
(me)
|
2008-08-20 |
2013-06-20 |
Zoetis Services Llc |
Jedinjenja pirolo (2,3-d) pirimidina
|
PT2344474E
(pt)
|
2008-09-02 |
2015-12-28 |
Novartis Ag |
Derivados de picolinamida como inibidores de cinase
|
JP5584215B2
(ja)
|
2008-09-02 |
2014-09-03 |
ノバルティス アーゲー |
ヘテロ環pimキナーゼ阻害剤
|
EP2342190A1
(en)
|
2008-09-02 |
2011-07-13 |
Novartis AG |
Bicyclic kinase inhibitors
|
CL2009001884A1
(es)
|
2008-10-02 |
2010-05-14 |
Incyte Holdings Corp |
Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
|
WO2010043052A1
(en)
*
|
2008-10-17 |
2010-04-22 |
Merck Frosst Canada Ltd. |
Azetidine derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
JOP20190230A1
(ar)
|
2009-01-15 |
2017-06-16 |
Incyte Corp |
طرق لاصلاح مثبطات انزيم jak و المركبات الوسيطة المتعلقة به
|
EP2210890A1
(en)
|
2009-01-19 |
2010-07-28 |
Almirall, S.A. |
Oxadiazole derivatives as S1P1 receptor agonists
|
US8263601B2
(en)
|
2009-02-27 |
2012-09-11 |
Concert Pharmaceuticals, Inc. |
Deuterium substituted xanthine derivatives
|
WO2010135650A1
(en)
*
|
2009-05-22 |
2010-11-25 |
Incyte Corporation |
N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS
|
WO2010135621A1
(en)
|
2009-05-22 |
2010-11-25 |
Incyte Corporation |
3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
|
UA110324C2
(en)
|
2009-07-02 |
2015-12-25 |
Genentech Inc |
Jak inhibitory compounds based on pyrazolo pyrimidine
|
WO2011003418A1
(en)
|
2009-07-08 |
2011-01-13 |
Leo Pharma A/S |
Heterocyclic compounds as jak receptor and protein tyrosine kinase inhibitors
|
WO2011025685A1
(en)
|
2009-08-24 |
2011-03-03 |
Merck Sharp & Dohme Corp. |
Jak inhibition blocks rna interference associated toxicities
|
TW201111385A
(en)
|
2009-08-27 |
2011-04-01 |
Biocryst Pharm Inc |
Heterocyclic compounds as janus kinase inhibitors
|
TW201113285A
(en)
|
2009-09-01 |
2011-04-16 |
Incyte Corp |
Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
|
SG178986A1
(en)
|
2009-09-08 |
2012-04-27 |
Hoffmann La Roche |
4-substituted pyridin-3-yl-carboxamide compounds and methods of use
|
EP2305660A1
(en)
|
2009-09-25 |
2011-04-06 |
Almirall, S.A. |
New thiadiazole derivatives
|
EP2486041B1
(en)
|
2009-10-09 |
2013-08-14 |
Incyte Corporation |
Hydroxyl, keto, and glucuronide derivatives of 3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
|
TW201125867A
(en)
|
2009-10-20 |
2011-08-01 |
Cellzome Ltd |
Heterocyclyl pyrazolopyrimidine analogues as JAK inhibitors
|
US8671402B2
(en)
|
2009-11-09 |
2014-03-11 |
Bank Of America Corporation |
Network-enhanced control of software updates received via removable computer-readable medium
|
EP2332917B1
(en)
|
2009-11-11 |
2012-08-01 |
Sygnis Bioscience GmbH & Co. KG |
Compounds for PIM kinase inhibition and for treating malignancy
|
EP2504030A4
(en)
|
2009-11-24 |
2013-06-26 |
Alderbio Holdings Llc |
IL-6 ANTAGONISTS FOR INCREASING ALBUMIN AND / OR REDUCING CRP
|
EP2506852A4
(en)
|
2009-12-04 |
2013-06-19 |
Univ Texas |
INTERFERONTHERAPIES IN COMBINATION WITH BLOCKING OF STAT3 ACTIVATION
|
CA2782720A1
(en)
|
2009-12-18 |
2011-06-23 |
Pfizer Inc. |
Pyrrolo[2,3-d]pyrimidine compounds
|
CA2781578A1
(en)
|
2010-01-12 |
2011-07-21 |
F. Hoffmann-La Roche Ag |
Tricyclic heterocyclic compounds, compositions and methods of use thereof
|
SA111320200B1
(ar)
|
2010-02-17 |
2014-02-16 |
ديبيوفارم اس ايه |
مركبات ثنائية الحلقة واستخداماتها كمثبطات c-src/jak مزدوجة
|
CA2790070C
(en)
|
2010-02-18 |
2018-03-06 |
Incyte Corporation |
Cyclobutane and methylcyclobutane derivatives as janus kinase inhibitors
|
ES2662588T3
(es)
|
2010-03-10 |
2018-04-09 |
Incyte Holdings Corporation |
Derivados de piperidin-4-IL azetidina como inhibidores de JAK1
|
NZ603446A
(en)
|
2010-04-14 |
2014-05-30 |
Array Biopharma Inc |
5, 7-substituted-imidazo [1, 2-c] pyrimidines as inhibitors of jak kinases
|
EP2390252A1
(en)
|
2010-05-19 |
2011-11-30 |
Almirall, S.A. |
New pyrazole derivatives
|
CN103002875B
(zh)
|
2010-05-21 |
2016-05-04 |
因塞特控股公司 |
Jak抑制剂的局部用制剂
|
WO2011156698A2
(en)
|
2010-06-11 |
2011-12-15 |
Abbott Laboratories |
NOVEL PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS
|
US9351943B2
(en)
|
2010-07-01 |
2016-05-31 |
Matthew T. McLeay |
Anti-fibroblastic fluorochemical emulsion therapies
|
US20130252917A1
(en)
|
2010-09-30 |
2013-09-26 |
Portola Pharmaceuticals, Inc. |
Combination therapy of 4-(3-(2h-1,2,3-triazo-2-yl)phenylamino)-2-((1r,2s)-2-aminocyclohexylamino)pyrimidine-5-carboxamide and fludarabine
|
AU2011329734B2
(en)
|
2010-11-19 |
2015-05-28 |
Incyte Holdings Corporation |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors
|
WO2012068440A1
(en)
|
2010-11-19 |
2012-05-24 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
|
MX2013006261A
(es)
|
2010-12-03 |
2013-10-01 |
Ym Biosciences Australia Pty |
Tratamiento de condiciones mediadas por jak2.
|
EA026317B1
(ru)
|
2011-02-18 |
2017-03-31 |
Новартис Фарма Аг |
КОМБИНИРОВАННОЕ ЛЕЧЕНИЕ С ПРИМЕНЕНИЕМ ИНГИБИТОРОВ mTOR/JAK
|
CN102247368B
(zh)
|
2011-05-19 |
2013-05-29 |
安徽永生堂药业有限责任公司 |
一种复方阿伐斯汀缓释片及其制备方法
|
CN102218042A
(zh)
|
2011-05-26 |
2011-10-19 |
青岛黄海制药有限责任公司 |
富马酸喹硫平组合物的缓释片剂及其制备方法
|
MY165963A
(en)
|
2011-06-20 |
2018-05-18 |
Incyte Holdings Corp |
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
|
WO2013007768A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
|
WO2013007765A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Fused tricyclic compounds for use as inhibitors of janus kinases
|
CA2844507A1
(en)
|
2011-08-10 |
2013-02-14 |
Novartis Pharma Ag |
Jak pi3k/mtor combination therapy
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為jak抑制劑之環己基氮雜環丁烷衍生物
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
US9193733B2
(en)
|
2012-05-18 |
2015-11-24 |
Incyte Holdings Corporation |
Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors
|
US10155987B2
(en)
|
2012-06-12 |
2018-12-18 |
Dana-Farber Cancer Institute, Inc. |
Methods of predicting resistance to JAK inhibitor therapy
|
WO2013188783A1
(en)
|
2012-06-15 |
2013-12-19 |
Concert Pharmaceuticals, Inc. |
Deuterated derivatives of ruxolitinib
|
WO2014016396A1
(en)
|
2012-07-27 |
2014-01-30 |
Ratiopharm Gmbh |
Oral dosage forms for modified release comprising ruxolitinib
|
CN102772384A
(zh)
|
2012-08-07 |
2012-11-14 |
四川百利药业有限责任公司 |
一种盐酸米诺环素缓释片及其制备方法
|
JP2015526520A
(ja)
|
2012-08-31 |
2015-09-10 |
プリンシピア バイオファーマ インコーポレイテッド |
Itk阻害剤としてのベンズイミダゾール誘導体
|
WO2014071031A1
(en)
|
2012-11-01 |
2014-05-08 |
Incyte Corporation |
Tricyclic fused thiophene derivatives as jak inhibitors
|
EA201590930A1
(ru)
|
2012-11-15 |
2015-08-31 |
Инсайт Корпорейшн |
Лекарственные формы руксолитиниба с замедленным высвобождением
|
CN105189509B
(zh)
|
2013-03-06 |
2017-12-19 |
因赛特公司 |
用于制备jak抑制剂的方法及中间体
|
HUE063817T2
(hu)
|
2013-05-17 |
2024-01-28 |
Incyte Holdings Corp |
Bipirazol-származékok mint JAK inhibitorok
|
SI3030227T1
(sl)
|
2013-08-07 |
2020-08-31 |
Incyte Corporation |
Dozirne oblike s podaljšanim sproščanjem za inhibitor JAK1
|
CN105555313A
(zh)
|
2013-08-20 |
2016-05-04 |
因赛特公司 |
在c-反应蛋白水平较高的实体肿瘤患者中的存活益处
|
EP3110409B1
(en)
|
2014-02-28 |
2018-08-15 |
Incyte Corporation |
Jak1 inhibitors for the treatment of myelodysplastic syndromes
|
EA201692011A1
(ru)
|
2014-04-08 |
2017-01-30 |
Инсайт Корпорейшн |
Лечение b-клеточных злокачественных новообразований с применением комбинации ингибиторов jak и pi3k
|
KR20170007331A
(ko)
|
2014-04-30 |
2017-01-18 |
인사이트 코포레이션 |
Jak1 억제제의 제조 방법 및 이에 대한 신규한 형태
|
WO2015184087A2
(en)
|
2014-05-28 |
2015-12-03 |
Institute For Myeloma & Bone Cancer Research |
Anti-cancer effects of jak2 inhibitors in combination with thalidomide derivatives and glucocorticoids
|
WO2015184305A1
(en)
*
|
2014-05-30 |
2015-12-03 |
Incyte Corporation |
TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1
|
US10766900B2
(en)
|
2017-12-29 |
2020-09-08 |
Formosa Laboratories, Inc. |
Baricitinib intermediate, method for forming Baricitinib intermediate, and method for preparing Baricitinib or pharmaceutically acceptable salt thereof
|
EP3921318A1
(en)
|
2019-02-06 |
2021-12-15 |
Concert Pharmaceuticals Inc. |
Process for preparing enantiomerically enriched jak inhibitors
|