DE60120198T2 - Pyrazolverbindungen als protein-kinasehemmer - Google Patents

Pyrazolverbindungen als protein-kinasehemmer Download PDF

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Publication number
DE60120198T2
DE60120198T2 DE60120198T DE60120198T DE60120198T2 DE 60120198 T2 DE60120198 T2 DE 60120198T2 DE 60120198 T DE60120198 T DE 60120198T DE 60120198 T DE60120198 T DE 60120198T DE 60120198 T2 DE60120198 T2 DE 60120198T2
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ring
optionally substituted
aliphatic
con
substituted
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Expired - Lifetime
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DE60120198T
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English (en)
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DE60120198D1 (de
Inventor
Robert Arlington DAVIES
David Newbury BEBBINGTON
Ronald Knegtel
Marion Stow WANNAMAKER
Pan Arlington LI
Cornelia Pelham FORESTER
Albert C. Cambridge PIERCE
David Purton KAY
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Chemical & Material Sciences (AREA)
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  • Diabetes (AREA)
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  • Biomedical Technology (AREA)
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  • Cardiology (AREA)
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DE60120198T 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer Expired - Lifetime DE60120198T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US23279500P 2000-09-15 2000-09-15
US232795P 2000-09-15
US25788700P 2000-12-21 2000-12-21
US257887P 2000-12-21
US28694901P 2001-04-27 2001-04-27
US286949P 2001-04-27
PCT/US2001/028940 WO2002022607A1 (en) 2000-09-15 2001-09-14 Pyrazole compounds useful as protein kinase inhibitors

Publications (2)

Publication Number Publication Date
DE60120198D1 DE60120198D1 (de) 2006-07-06
DE60120198T2 true DE60120198T2 (de) 2007-05-10

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ID=27398347

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Application Number Title Priority Date Filing Date
DE60120198T Expired - Lifetime DE60120198T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60119748T Expired - Lifetime DE60119748T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60110616T Expired - Lifetime DE60110616T3 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60124744T Expired - Lifetime DE60124744T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60120193T Expired - Lifetime DE60120193T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60120194T Expired - Lifetime DE60120194T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60119749T Expired - Lifetime DE60119749T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60128709T Expired - Lifetime DE60128709T2 (de) 2000-09-15 2001-09-14 Triazol-verbindungen als protein-kinase-inhibitoren

Family Applications After (7)

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DE60119748T Expired - Lifetime DE60119748T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60110616T Expired - Lifetime DE60110616T3 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60124744T Expired - Lifetime DE60124744T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60120193T Expired - Lifetime DE60120193T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60120194T Expired - Lifetime DE60120194T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60119749T Expired - Lifetime DE60119749T2 (de) 2000-09-15 2001-09-14 Pyrazolverbindungen als protein-kinasehemmer
DE60128709T Expired - Lifetime DE60128709T2 (de) 2000-09-15 2001-09-14 Triazol-verbindungen als protein-kinase-inhibitoren

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US (7) US7115739B2 (OSRAM)
EP (8) EP1318997B1 (OSRAM)
JP (9) JP4105948B2 (OSRAM)
KR (4) KR20030032035A (OSRAM)
CN (3) CN1473161A (OSRAM)
AP (1) AP2003002762A0 (OSRAM)
AT (8) ATE326458T1 (OSRAM)
AU (9) AU2001296871A1 (OSRAM)
BR (1) BR0114088A (OSRAM)
CA (8) CA2422354C (OSRAM)
DE (8) DE60120198T2 (OSRAM)
DK (1) DK1318997T3 (OSRAM)
ES (3) ES2242771T5 (OSRAM)
HU (4) HUP0302411A2 (OSRAM)
IL (6) IL154747A0 (OSRAM)
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NO (4) NO327708B1 (OSRAM)
NZ (4) NZ525009A (OSRAM)
PE (1) PE20020451A1 (OSRAM)
PL (1) PL361676A1 (OSRAM)
PT (2) PT1317448E (OSRAM)
TW (1) TWI303636B (OSRAM)
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