ATE325113T1 - Pharmacologisch wirksame pyrimidinderivate und verfahren zu deren herstellung - Google Patents

Pharmacologisch wirksame pyrimidinderivate und verfahren zu deren herstellung

Info

Publication number
ATE325113T1
ATE325113T1 AT94928384T AT94928384T ATE325113T1 AT E325113 T1 ATE325113 T1 AT E325113T1 AT 94928384 T AT94928384 T AT 94928384T AT 94928384 T AT94928384 T AT 94928384T AT E325113 T1 ATE325113 T1 AT E325113T1
Authority
AT
Austria
Prior art keywords
substituted
pct
lower alkyl
date
cyclic radical
Prior art date
Application number
AT94928384T
Other languages
English (en)
Inventor
Juerg Zimmermann
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE325113T1 publication Critical patent/ATE325113T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT94928384T 1993-10-01 1994-09-21 Pharmacologisch wirksame pyrimidinderivate und verfahren zu deren herstellung ATE325113T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH296893 1993-10-01
CH228094 1994-07-18

Publications (1)

Publication Number Publication Date
ATE325113T1 true ATE325113T1 (de) 2006-06-15

Family

ID=25690000

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94928384T ATE325113T1 (de) 1993-10-01 1994-09-21 Pharmacologisch wirksame pyrimidinderivate und verfahren zu deren herstellung

Country Status (9)

Country Link
US (1) US5705502A (de)
EP (1) EP0672042B1 (de)
JP (1) JP3588116B2 (de)
AT (1) ATE325113T1 (de)
AU (1) AU693114B2 (de)
DE (1) DE69434721T2 (de)
ES (1) ES2262137T3 (de)
PT (1) PT672042E (de)
WO (1) WO1995009851A1 (de)

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DK3321262T3 (da) 2012-03-01 2021-01-25 Array Biopharma Inc Serin-/threoninkinasehæmmere
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Also Published As

Publication number Publication date
US5705502A (en) 1998-01-06
AU693114B2 (en) 1998-06-25
EP0672042B1 (de) 2006-05-03
PT672042E (pt) 2006-08-31
DE69434721T2 (de) 2006-11-09
JP3588116B2 (ja) 2004-11-10
JPH08503970A (ja) 1996-04-30
EP0672042A1 (de) 1995-09-20
DE69434721D1 (de) 2006-06-08
AU7783394A (en) 1995-05-01
ES2262137T3 (es) 2006-11-16
WO1995009851A1 (en) 1995-04-13

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