DE69411380D1 - Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung - Google Patents

Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung

Info

Publication number
DE69411380D1
DE69411380D1 DE69411380T DE69411380T DE69411380D1 DE 69411380 D1 DE69411380 D1 DE 69411380D1 DE 69411380 T DE69411380 T DE 69411380T DE 69411380 T DE69411380 T DE 69411380T DE 69411380 D1 DE69411380 D1 DE 69411380D1
Authority
DE
Germany
Prior art keywords
acyldipeptides
pct
group
organic groups
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69411380T
Other languages
English (en)
Other versions
DE69411380T2 (de
Inventor
Danijel Kikelj
Elizabeta Suhadolc
Alenka Rutar
Slavko Pecar
Alesa Puncuh
Uros Urleb
Vesna Leskovsek
Gasper Marc
Marija Sollner
Ales Krbavcic
Gregor Sersa
Srdjan Novakovic
Lucka Povsic
Anton Stalc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LJUBLJANI, University of
Lek Pharmaceuticals dd
Univerza Ljubljana v Fakulteta za Farmazijo
Original Assignee
LJUBLJANI, University of
Univerza Ljubljana v Fakulteta za Farmazijo
Lek Pharmaceuticals and Chemical Co dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LJUBLJANI, University of, Univerza Ljubljana v Fakulteta za Farmazijo, Lek Pharmaceuticals and Chemical Co dd filed Critical LJUBLJANI, University of
Application granted granted Critical
Publication of DE69411380D1 publication Critical patent/DE69411380D1/de
Publication of DE69411380T2 publication Critical patent/DE69411380T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
DE69411380T 1993-04-22 1994-04-21 Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung Expired - Fee Related DE69411380T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI9300212A SI9300212A (en) 1993-04-22 1993-04-22 Novel N-acyldipeptides, process for the preparation thereof and pharmaceutical composition containing the same
PCT/SI1994/000003 WO1994024152A1 (en) 1993-04-22 1994-04-21 Novel heterocyclic acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same

Publications (2)

Publication Number Publication Date
DE69411380D1 true DE69411380D1 (de) 1998-08-06
DE69411380T2 DE69411380T2 (de) 1999-04-01

Family

ID=20431165

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69411380T Expired - Fee Related DE69411380T2 (de) 1993-04-22 1994-04-21 Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung

Country Status (8)

Country Link
US (1) US5824652A (de)
EP (1) EP0695308B1 (de)
JP (1) JP2886987B2 (de)
AT (1) ATE167873T1 (de)
DE (1) DE69411380T2 (de)
ES (1) ES2120039T3 (de)
SI (1) SI9300212A (de)
WO (1) WO1994024152A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2311411B1 (es) * 2007-07-19 2010-01-08 Universidad De Cadiz. Derivados 2-alquil-2h-1, 4-benzoxacin-3(4h)-ona y 2-alcoxicarbonil-2h-1,4-benzoxacin-3(4h)-ona, con actividad fitotoxica.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2326930A1 (fr) * 1975-10-09 1977-05-06 Anvar Agents hydrosolubles depresseurs non specifiques des reponses immunitaires
US4322341A (en) * 1980-05-13 1982-03-30 Fujisawa Pharmaceutical Co Peptide, process for preparation thereof and use thereof
YU183090A (sh) * 1990-09-27 1992-12-21 Lek Novi n-acildipeptidi, postopki za njihovo pripravo in farmacevtski pripravki, kojih vsebujejo
US5321216A (en) * 1991-04-09 1994-06-14 Otis Elevator Company Restraining elevator car motion while the doors are open

Also Published As

Publication number Publication date
WO1994024152A1 (en) 1994-10-27
DE69411380T2 (de) 1999-04-01
JPH09506856A (ja) 1997-07-08
SI9300212A (en) 1994-12-31
ATE167873T1 (de) 1998-07-15
JP2886987B2 (ja) 1999-04-26
ES2120039T3 (es) 1998-10-16
EP0695308A1 (de) 1996-02-07
EP0695308B1 (de) 1998-07-01
US5824652A (en) 1998-10-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee