AR007828A1 - Compuestos derivados de piridilpirrol, procedimiento de preparacion y composiciones farmaceuticas conteniendo los mismos - Google Patents

Compuestos derivados de piridilpirrol, procedimiento de preparacion y composiciones farmaceuticas conteniendo los mismos

Info

Publication number
AR007828A1
AR007828A1 ARP970103050A ARP970103050A AR007828A1 AR 007828 A1 AR007828 A1 AR 007828A1 AR P970103050 A ARP970103050 A AR P970103050A AR P970103050 A ARP970103050 A AR P970103050A AR 007828 A1 AR007828 A1 AR 007828A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical compositions
piridilpirrol
same
compositions containing
preparation procedure
Prior art date
Application number
ARP970103050A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of AR007828A1 publication Critical patent/AR007828A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Un compuesto derivado de piridil pirrol de fórmula (I) y sus sales farmacéuticamente aceptables, donde R1, R2, R3, R4, R5 y m son tal como sedefinen en la reivindicación 1. También aporta procedimientos para la preparación delmis mo, útil en el tratamiento de enfermedades en las queintervienen moléculas de adhesión celular (CAMs) y composiciones farmacéuticas para usarse en tal terapia.
ARP970103050A 1996-07-11 1997-07-08 Compuestos derivados de piridilpirrol, procedimiento de preparacion y composiciones farmaceuticas conteniendo los mismos AR007828A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9600671 1996-07-11

Publications (1)

Publication Number Publication Date
AR007828A1 true AR007828A1 (es) 1999-11-24

Family

ID=11004451

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970103050A AR007828A1 (es) 1996-07-11 1997-07-08 Compuestos derivados de piridilpirrol, procedimiento de preparacion y composiciones farmaceuticas conteniendo los mismos

Country Status (14)

Country Link
US (1) US6417202B1 (es)
EP (1) EP0912548A1 (es)
AP (1) AP9701041A0 (es)
AR (1) AR007828A1 (es)
AU (1) AU3044197A (es)
BR (1) BR9710352A (es)
CA (1) CA2260213C (es)
HN (1) HN1997000090A (es)
HR (1) HRP970378A2 (es)
ID (1) ID19476A (es)
MA (1) MA26433A1 (es)
PA (1) PA8432901A1 (es)
TN (1) TNSN97119A1 (es)
WO (1) WO1998002430A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6608060B1 (en) 1996-12-18 2003-08-19 Vertex Pharmaceuticals Incorporated Inhibitors of p38
US6147080A (en) * 1996-12-18 2000-11-14 Vertex Pharmaceuticals Incorporated Inhibitors of p38
US5945418A (en) * 1996-12-18 1999-08-31 Vertex Pharmaceuticals Incorporated Inhibitors of p38
PT853083E (pt) * 1997-01-06 2001-12-28 Pfizer Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica
FR2771412B1 (fr) * 1997-11-26 2000-04-28 Adir Nouveaux derives de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR20010034114A (ko) * 1998-01-14 2001-04-25 니뽄 신야쿠 가부시키가이샤 칼륨 채널 활성화제
WO1999061016A1 (fr) * 1998-05-27 1999-12-02 Nippon Shinyaku Co., Ltd. Inhibiteurs de cyclo-oxygenase-2
WO2000066124A1 (fr) * 1999-04-28 2000-11-09 Sankyo Company, Limited Agents preventifs ou inhibiteurs destines a une hepatopathie
PT1178981E (pt) * 1999-05-14 2003-11-28 Ortho Mcneil Pharm Inc 3-piridil-4-arilpirrois substituidos e metodos terapeuticos e profilacticos
EP1652839A3 (en) * 1999-10-28 2006-07-05 Daiichi Pharmaceutical Co., Ltd. Drug efflux pump inhibitor
GB0003154D0 (en) * 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
GB0016453D0 (en) 2000-07-04 2000-08-23 Hoffmann La Roche Pyrrole derivatives
EP1352906A4 (en) * 2001-01-18 2004-06-16 Sankyo Co COMPOSITIONS FOR PREVENTION OR TREATMENT OF LIVER DISEASES
WO2002087589A1 (en) * 2001-04-26 2002-11-07 Daiichi Pharmaceutical Co., Ltd. Medicine for inhibiting drug elimination pump
US7056917B2 (en) * 2001-04-26 2006-06-06 Daiichi Pharmaceutical Co., Ltd. Drug efflux pump inhibitor
SE0102616D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
SE0102617D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
EP1423378B1 (en) 2001-08-30 2005-11-09 F. Hoffmann-La Roche Ag Aminopyrrole compounds as antiinflammatory agents
WO2004058176A2 (en) * 2002-12-20 2004-07-15 Pharmacia Corporation Acyclic pyrazole compounds
SE0300092D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300091D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
US20050043346A1 (en) * 2003-08-08 2005-02-24 Pharmacia Italia S.P.A. Pyridylpyrrole derivatives active as kinase inhibitors
EP1729776A1 (en) * 2004-02-20 2006-12-13 AstraZeneca AB Pyrrole derivatives as gonadotropin releasing hormone (gnrh) antagonists
KR20080080373A (ko) * 2005-12-19 2008-09-03 신젠타 리미티드 살진균제로서 치환된 방향족 헤테로사이클 화합물
US7618982B2 (en) * 2005-12-19 2009-11-17 Nerviano Medical Sciences S.R.L. Heteroarylpyrrolopyridinones active as kinase inhibitors
KR20090008286A (ko) 2006-03-27 2009-01-21 네르비아노 메디칼 사이언시스 에스.알.엘. 키나제 억제제로서의 피리딜- 및 피리미디닐-치환된 피롤-,티오펜- 및 푸란- 유도체
JP2010504295A (ja) 2006-09-21 2010-02-12 ノバルティス アーゲー サイトカイン介在疾患の処置に有用なピロール誘導体
CN104379573A (zh) * 2012-04-20 2015-02-25 艾伯维公司 异吲哚酮衍生物
CA2870931A1 (en) * 2012-04-20 2013-10-24 Abbvie Inc. Isoindolone derivatives
US9493411B2 (en) * 2013-03-12 2016-11-15 Abbvie Inc. Pyrrole-3-carboxamide bromodomain inhibitors
US10428044B2 (en) 2014-06-17 2019-10-01 Bayer Pharma Aktiengesellschaft 3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones
CA3008393A1 (en) * 2015-12-16 2017-06-22 Bayer Pharma Aktiengesellschaft Hetero-1,5,6,7-tetrahydro-4h-indol-4-ones

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356897A (en) 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
CA2228050A1 (en) 1995-08-10 1997-02-20 Harold G. Selnick 2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use
DE69627006T2 (de) 1995-08-10 2004-01-15 Merck & Co Inc 2-substituierte aryl-pyrrolen, zusammensetzungen solche verbindungen enthaltend und deren verwendung
AU7529096A (en) * 1995-10-31 1997-05-22 Merck & Co., Inc. Substituted aryl pyrroles, compositions containing such compounds and methods of use
EP0859771A4 (en) * 1995-10-31 2000-03-15 Merck & Co Inc SUBSTITUTED PYRIDYLPYRROLE, PREPARATIONS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE USE THEREOF
WO1997016441A1 (en) 1995-10-31 1997-05-09 Merck & Co., Inc. Substituted aryl pyrroles, compositions containing such compounds and methods of use
US5776954A (en) * 1996-10-30 1998-07-07 Merck & Co., Inc. Substituted pyridyl pyrroles, compositions containing such compounds and methods of use

Also Published As

Publication number Publication date
BR9710352A (pt) 1999-08-17
CA2260213C (en) 2005-03-29
EP0912548A1 (en) 1999-05-06
AP9701041A0 (en) 1999-01-10
TNSN97119A1 (fr) 2005-03-15
US6417202B1 (en) 2002-07-09
PA8432901A1 (es) 2000-05-24
US20020049235A1 (en) 2002-04-25
HN1997000090A (es) 1997-12-26
MA26433A1 (fr) 2004-12-20
CA2260213A1 (en) 1998-01-22
ID19476A (id) 1998-07-16
HRP970378A2 (en) 1998-08-31
AU3044197A (en) 1998-02-09
WO1998002430A1 (en) 1998-01-22

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