BR9710352A - Compostos piridilpirrole - Google Patents

Compostos piridilpirrole

Info

Publication number
BR9710352A
BR9710352A BR9710352A BR9710352A BR9710352A BR 9710352 A BR9710352 A BR 9710352A BR 9710352 A BR9710352 A BR 9710352A BR 9710352 A BR9710352 A BR 9710352A BR 9710352 A BR9710352 A BR 9710352A
Authority
BR
Brazil
Prior art keywords
pyridylpyrrole
compounds
pyridylpyrrole compounds
Prior art date
Application number
BR9710352A
Other languages
English (en)
Inventor
Akiyoshi Kawai
Makoto Kawai
Yoshinori Murata
Junji Takada
Minoru Sakakibara
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9710352A publication Critical patent/BR9710352A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
BR9710352A 1996-07-11 1997-06-16 Compostos piridilpirrole BR9710352A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9600671 1996-07-11
PCT/IB1997/000703 WO1998002430A1 (en) 1996-07-11 1997-06-16 Pyridylpyrrole compounds useful as interleukin- and tnf antagonists

Publications (1)

Publication Number Publication Date
BR9710352A true BR9710352A (pt) 1999-08-17

Family

ID=11004451

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710352A BR9710352A (pt) 1996-07-11 1997-06-16 Compostos piridilpirrole

Country Status (14)

Country Link
US (1) US6417202B1 (pt)
EP (1) EP0912548A1 (pt)
AP (1) AP9701041A0 (pt)
AR (1) AR007828A1 (pt)
AU (1) AU3044197A (pt)
BR (1) BR9710352A (pt)
CA (1) CA2260213C (pt)
HN (1) HN1997000090A (pt)
HR (1) HRP970378A2 (pt)
ID (1) ID19476A (pt)
MA (1) MA26433A1 (pt)
PA (1) PA8432901A1 (pt)
TN (1) TNSN97119A1 (pt)
WO (1) WO1998002430A1 (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945418A (en) * 1996-12-18 1999-08-31 Vertex Pharmaceuticals Incorporated Inhibitors of p38
US6608060B1 (en) 1996-12-18 2003-08-19 Vertex Pharmaceuticals Incorporated Inhibitors of p38
US6147080A (en) * 1996-12-18 2000-11-14 Vertex Pharmaceuticals Incorporated Inhibitors of p38
PT853083E (pt) * 1997-01-06 2001-12-28 Pfizer Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica
FR2771412B1 (fr) * 1997-11-26 2000-04-28 Adir Nouveaux derives de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2204390C2 (ru) * 1998-01-14 2003-05-20 Ниппон Синяку Ко., Лтд. Активаторы калиевых каналов
AU3953899A (en) * 1998-05-27 1999-12-13 Nippon Shinyaku Co. Ltd. Cyclooxygenase-2 inhibitors
WO2000066124A1 (fr) * 1999-04-28 2000-11-09 Sankyo Company, Limited Agents preventifs ou inhibiteurs destines a une hepatopathie
RU2238940C2 (ru) * 1999-05-14 2004-10-27 Орто-Макнейл Фармасьютикал, Инк. Замещенные 3-пиридил-4-арилпирролы и связанные с ними терапевтические и профилактические способы
ATE312820T1 (de) * 1999-10-28 2005-12-15 Trine Pharmaceuticals Inc Pumpeninhibitoren zur freisetzung von medikamenten
GB0003154D0 (en) * 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
GB0016453D0 (en) * 2000-07-04 2000-08-23 Hoffmann La Roche Pyrrole derivatives
WO2002057254A1 (fr) * 2001-01-18 2002-07-25 Sankyo Company, Limited Compositions destinees a la prevention et au traitement de l'hepatopathie
US7056917B2 (en) * 2001-04-26 2006-06-06 Daiichi Pharmaceutical Co., Ltd. Drug efflux pump inhibitor
EP1389463A4 (en) * 2001-04-26 2008-09-17 Daiichi Seiyaku Co MEDICAMENT FOR INHIBITING A DRUG REMOVAL PUMP
SE0102617D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
SE0102616D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
DE60207273T2 (de) 2001-08-30 2006-07-20 F. Hoffmann-La Roche Ag Aminopyrrolverbindungen als entzündungshemmende Wirkstoffe
CA2509565A1 (en) * 2002-12-20 2004-07-15 Pharmacia Corporation Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds
SE0300092D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300091D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
US20050043346A1 (en) * 2003-08-08 2005-02-24 Pharmacia Italia S.P.A. Pyridylpyrrole derivatives active as kinase inhibitors
JP2007523145A (ja) * 2004-02-20 2007-08-16 アストラゼネカ アクチボラグ ゴナドトロピン放出ホルモン(gnrh)アンタゴニストとしてのピロール誘導体
US7618982B2 (en) * 2005-12-19 2009-11-17 Nerviano Medical Sciences S.R.L. Heteroarylpyrrolopyridinones active as kinase inhibitors
CA2632565A1 (en) * 2005-12-19 2007-07-05 Syngenta Limited Substituted aromatic heterocyclic compounds as fungicides
SG173320A1 (en) * 2006-03-27 2011-08-29 Nerviano Medical Sciences Srl Pyridyl- and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitors
RU2009114747A (ru) 2006-09-21 2010-10-27 Новартис АГ (CH) Производные пиррола, применимые в лечении цитокин-опосредованных заболеваний
CA2870931A1 (en) * 2012-04-20 2013-10-24 Abbvie Inc. Isoindolone derivatives
CN104379573A (zh) * 2012-04-20 2015-02-25 艾伯维公司 异吲哚酮衍生物
BR112015022551A2 (pt) * 2013-03-12 2017-07-18 Abbvie Inc inibidores de amido pirrol
EP3157914B1 (en) 2014-06-17 2018-09-26 Bayer Pharma Aktiengesellschaft 3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones
CN108602820A (zh) * 2015-12-16 2018-09-28 拜耳制药股份公司 杂-1,5,6,7-四氢-4h-吲哚-4-酮类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356897A (en) 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
WO1997005878A1 (en) * 1995-08-10 1997-02-20 Merck & Co., Inc. 2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use
ATE235239T1 (de) * 1995-08-10 2003-04-15 Merck & Co Inc 2-substituierte aryl-pyrrolen, zusammensetzungen solche verbindungen enthaltend und deren verwendung
AU7482396A (en) * 1995-10-31 1997-05-22 Merck & Co., Inc. Substituted aryl pyrroles, compositions containing such compounds and methods of use
AU7529096A (en) 1995-10-31 1997-05-22 Merck & Co., Inc. Substituted aryl pyrroles, compositions containing such compounds and methods of use
JPH11514651A (ja) * 1995-10-31 1999-12-14 メルク エンド カンパニー インコーポレーテッド 置換ピリジルピロール、前記化合物を含む組成物及び使用方法
US5776954A (en) * 1996-10-30 1998-07-07 Merck & Co., Inc. Substituted pyridyl pyrroles, compositions containing such compounds and methods of use

Also Published As

Publication number Publication date
US6417202B1 (en) 2002-07-09
US20020049235A1 (en) 2002-04-25
EP0912548A1 (en) 1999-05-06
AU3044197A (en) 1998-02-09
CA2260213A1 (en) 1998-01-22
AP9701041A0 (en) 1999-01-10
HRP970378A2 (en) 1998-08-31
ID19476A (id) 1998-07-16
WO1998002430A1 (en) 1998-01-22
CA2260213C (en) 2005-03-29
TNSN97119A1 (fr) 2005-03-15
MA26433A1 (fr) 2004-12-20
AR007828A1 (es) 1999-11-24
PA8432901A1 (es) 2000-05-24
HN1997000090A (es) 1997-12-26

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Legal Events

Date Code Title Description
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements