ATE167873T1 - Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung - Google Patents

Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung

Info

Publication number
ATE167873T1
ATE167873T1 AT94914681T AT94914681T ATE167873T1 AT E167873 T1 ATE167873 T1 AT E167873T1 AT 94914681 T AT94914681 T AT 94914681T AT 94914681 T AT94914681 T AT 94914681T AT E167873 T1 ATE167873 T1 AT E167873T1
Authority
AT
Austria
Prior art keywords
acyldipeptides
pct
group
production
pharmaceutical composition
Prior art date
Application number
AT94914681T
Other languages
English (en)
Inventor
Danijel Kikelj
Elizabeta Suhadolc
Alenka Rutar
Slavko Pecar
Alesa Puncuh
Uros Urleb
Vesna Leskovsek
Gasper Marc
Marija Sollner
Ales Krbavcic
Gregor Sersa
Srdjan Novakovic
Lucka Povsic
Anton Stalc
Original Assignee
Univ Ljubljani
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ljubljani, Lek Tovarna Farmacevtskih filed Critical Univ Ljubljani
Application granted granted Critical
Publication of ATE167873T1 publication Critical patent/ATE167873T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
AT94914681T 1993-04-22 1994-04-21 Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung ATE167873T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI9300212A SI9300212A (en) 1993-04-22 1993-04-22 Novel N-acyldipeptides, process for the preparation thereof and pharmaceutical composition containing the same

Publications (1)

Publication Number Publication Date
ATE167873T1 true ATE167873T1 (de) 1998-07-15

Family

ID=20431165

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94914681T ATE167873T1 (de) 1993-04-22 1994-04-21 Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung

Country Status (8)

Country Link
US (1) US5824652A (de)
EP (1) EP0695308B1 (de)
JP (1) JP2886987B2 (de)
AT (1) ATE167873T1 (de)
DE (1) DE69411380T2 (de)
ES (1) ES2120039T3 (de)
SI (1) SI9300212A (de)
WO (1) WO1994024152A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2311411B1 (es) * 2007-07-19 2010-01-08 Universidad De Cadiz. Derivados 2-alquil-2h-1, 4-benzoxacin-3(4h)-ona y 2-alcoxicarbonil-2h-1,4-benzoxacin-3(4h)-ona, con actividad fitotoxica.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2326930A1 (fr) * 1975-10-09 1977-05-06 Anvar Agents hydrosolubles depresseurs non specifiques des reponses immunitaires
US4322341A (en) * 1980-05-13 1982-03-30 Fujisawa Pharmaceutical Co Peptide, process for preparation thereof and use thereof
YU183090A (sh) * 1990-09-27 1992-12-21 Lek Novi n-acildipeptidi, postopki za njihovo pripravo in farmacevtski pripravki, kojih vsebujejo
US5321216A (en) * 1991-04-09 1994-06-14 Otis Elevator Company Restraining elevator car motion while the doors are open

Also Published As

Publication number Publication date
JPH09506856A (ja) 1997-07-08
EP0695308B1 (de) 1998-07-01
JP2886987B2 (ja) 1999-04-26
SI9300212A (en) 1994-12-31
DE69411380T2 (de) 1999-04-01
US5824652A (en) 1998-10-20
ES2120039T3 (es) 1998-10-16
WO1994024152A1 (en) 1994-10-27
DE69411380D1 (de) 1998-08-06
EP0695308A1 (de) 1996-02-07

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