ATE212996T1 - Anthracyclin-derivate - Google Patents

Anthracyclin-derivate

Info

Publication number
ATE212996T1
ATE212996T1 AT95932665T AT95932665T ATE212996T1 AT E212996 T1 ATE212996 T1 AT E212996T1 AT 95932665 T AT95932665 T AT 95932665T AT 95932665 T AT95932665 T AT 95932665T AT E212996 T1 ATE212996 T1 AT E212996T1
Authority
AT
Austria
Prior art keywords
pct
date
sec
formula
anthracycline derivatives
Prior art date
Application number
AT95932665T
Other languages
English (en)
Inventor
Antonino Suarato
Michele Caruso
Alberto Bargiotti
Dario Ballinari
Jacqueline Lansen
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Application granted granted Critical
Publication of ATE212996T1 publication Critical patent/ATE212996T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT95932665T 1994-09-09 1995-09-05 Anthracyclin-derivate ATE212996T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9418260A GB9418260D0 (en) 1994-09-09 1994-09-09 Anthracycline derivatives
PCT/EP1995/003480 WO1996007665A1 (en) 1994-09-09 1995-09-05 Anthracycline derivatives

Publications (1)

Publication Number Publication Date
ATE212996T1 true ATE212996T1 (de) 2002-02-15

Family

ID=10761136

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95932665T ATE212996T1 (de) 1994-09-09 1995-09-05 Anthracyclin-derivate

Country Status (27)

Country Link
US (1) US5744454A (de)
EP (1) EP0728138B1 (de)
JP (1) JP4060881B2 (de)
KR (1) KR100451682B1 (de)
CN (1) CN1051558C (de)
AT (1) ATE212996T1 (de)
CA (1) CA2176144C (de)
CZ (1) CZ292302B6 (de)
DE (1) DE69525327T2 (de)
DK (1) DK0728138T3 (de)
ES (1) ES2173195T3 (de)
FI (1) FI961915A0 (de)
GB (1) GB9418260D0 (de)
HU (1) HUT75535A (de)
IL (1) IL115184A (de)
MX (1) MX9601635A (de)
MY (1) MY114282A (de)
NO (1) NO310098B1 (de)
NZ (1) NZ293243A (de)
PL (1) PL184009B1 (de)
PT (1) PT728138E (de)
RU (1) RU2159619C2 (de)
SI (1) SI0728138T1 (de)
TW (1) TW458954B (de)
UA (1) UA61875C2 (de)
WO (1) WO1996007665A1 (de)
ZA (1) ZA957525B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9516349D0 (en) * 1995-08-09 1995-10-11 Pharmacia Spa Aza-anthracyclinone derivatives
GB9613433D0 (en) * 1996-06-26 1996-08-28 Pharmacia Spa Fluoro labelled anthracyclinone and anthracycline derivatives
GB9701628D0 (en) * 1997-01-27 1997-03-19 Pharmacia & Upjohn Spa Imino-aza-anthracyclinone derivatives
US6221614B1 (en) * 1997-02-21 2001-04-24 The Regents Of The University Of California Removal of prions from blood, plasma and other liquids
GB9805082D0 (en) * 1998-03-10 1998-05-06 Pharmacia & Upjohn Spa Heterocyclyl anthracyclinone derivatives
AU2001286744A1 (en) * 2000-08-25 2002-03-04 Beth Israel Deaconess Medical Center Compounds and methods for inhibiting neuronal cell death
US6624317B1 (en) 2000-09-25 2003-09-23 The University Of North Carolina At Chapel Hill Taxoid conjugates as antimitotic and antitumor agents
US20040191385A1 (en) * 2003-03-26 2004-09-30 Council Of Scientific And Industrial Research Composition for stabilizing pink color of fresh large cardamom and a process for stabilizing the pink color of large cardamom
US7244829B2 (en) * 2004-11-08 2007-07-17 Gem Pharmaceuticals, Llc Compositions and processes for preparing 13-deoxy-anthracyclines
MX2010011079A (es) * 2008-04-11 2012-06-01 Tianjin Hemay Bio Tech Co Ltd Derivados antibioticos de antraquinona tetraciclica con alta actividad, proceso para preparar los mismos y uso de estos.
WO2020041541A2 (en) 2018-08-23 2020-02-27 Seattle Genetics, Inc. Anti-tigit antibodies

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
US4133877A (en) * 1976-07-08 1979-01-09 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and use therefor
GB1524468A (en) * 1976-07-13 1978-09-13 Farmaceutici Italia Anthracylines
GB1567456A (en) * 1976-11-16 1980-05-14 Farmaceutici Italia Daunomycin derivatives
GB8321676D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia 4'-haloanthrocycline glycosides
GB8414619D0 (en) * 1984-06-08 1984-07-11 Erba Farmitalia Anthracyclines
DE3500017A1 (de) * 1985-01-02 1986-07-10 Farmitalia Carlo Erba S.p.A., Mailand/Milano 4'-haloanthracyclinester
GB2218087B (en) * 1988-04-22 1991-01-30 Erba Carlo Spa 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides
GB2238540B (en) * 1989-11-29 1993-09-29 Erba Carlo Spa 13-deoxy-4'-deoxy-4'-iodoanthracyclines
IL110289A (en) * 1993-08-06 1998-01-04 Policlinico San Matteo Istitut Pharmaceutical preparations containing 4-iodo-4-deoxydoxorubicin for the treatment of amyloidosis

Also Published As

Publication number Publication date
MX9601635A (es) 1997-03-29
DK0728138T3 (da) 2002-05-13
AU3563495A (en) 1996-03-27
ES2173195T3 (es) 2002-10-16
CN1051558C (zh) 2000-04-19
PT728138E (pt) 2002-07-31
EP0728138B1 (de) 2002-02-06
CZ133396A3 (en) 1996-10-16
HUT75535A (en) 1997-05-28
CN1135219A (zh) 1996-11-06
NO310098B1 (no) 2001-05-21
GB9418260D0 (en) 1994-10-26
CA2176144C (en) 2006-06-20
PL314269A1 (en) 1996-09-02
SI0728138T1 (en) 2002-08-31
WO1996007665A1 (en) 1996-03-14
CA2176144A1 (en) 1996-03-14
DE69525327T2 (de) 2002-10-02
FI961915A (fi) 1996-05-06
NZ293243A (en) 2001-03-30
KR100451682B1 (ko) 2005-09-20
AU691340B2 (en) 1998-05-14
KR960705577A (ko) 1996-11-08
ZA957525B (en) 1996-03-28
UA61875C2 (en) 2003-12-15
FI961915A0 (fi) 1996-05-06
JPH09505321A (ja) 1997-05-27
MY114282A (en) 2002-09-30
DE69525327D1 (de) 2002-03-21
JP4060881B2 (ja) 2008-03-12
RU2159619C2 (ru) 2000-11-27
TW458954B (en) 2001-10-11
HU9601587D0 (en) 1996-08-28
EP0728138A1 (de) 1996-08-28
NO961860D0 (no) 1996-05-08
IL115184A0 (en) 1995-12-31
PL184009B1 (pl) 2002-08-30
US5744454A (en) 1998-04-28
CZ292302B6 (cs) 2003-09-17
NO961860L (no) 1996-07-08
IL115184A (en) 2003-02-12

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