GB2238540B - 13-deoxy-4'-deoxy-4'-iodoanthracyclines - Google Patents

13-deoxy-4'-deoxy-4'-iodoanthracyclines

Info

Publication number
GB2238540B
GB2238540B GB8927000A GB8927000A GB2238540B GB 2238540 B GB2238540 B GB 2238540B GB 8927000 A GB8927000 A GB 8927000A GB 8927000 A GB8927000 A GB 8927000A GB 2238540 B GB2238540 B GB 2238540B
Authority
GB
United Kingdom
Prior art keywords
deoxy
iodoanthracyclines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8927000A
Other versions
GB2238540A (en
GB8927000D0 (en
Inventor
Antonino Suarato
Michele Caruso
Maria Grandi
Stefania Stefanelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Priority to GB8927000A priority Critical patent/GB2238540B/en
Publication of GB8927000D0 publication Critical patent/GB8927000D0/en
Priority to IT02204790A priority patent/IT1245851B/en
Priority to JP2322250A priority patent/JPH03190892A/en
Priority to DE4037693A priority patent/DE4037693A1/en
Publication of GB2238540A publication Critical patent/GB2238540A/en
Application granted granted Critical
Publication of GB2238540B publication Critical patent/GB2238540B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
GB8927000A 1989-11-29 1989-11-29 13-deoxy-4'-deoxy-4'-iodoanthracyclines Expired - Fee Related GB2238540B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB8927000A GB2238540B (en) 1989-11-29 1989-11-29 13-deoxy-4'-deoxy-4'-iodoanthracyclines
IT02204790A IT1245851B (en) 1989-11-29 1990-11-14 13-DESOSSO-4'-deoxy-4'-IODOANTRACICLINE
JP2322250A JPH03190892A (en) 1989-11-29 1990-11-26 3-deoxo-4'-deoxy-4'-iodoanthracycline
DE4037693A DE4037693A1 (en) 1989-11-29 1990-11-27 13-DEOXO-4'-DEOXY-4'-JODANTHRACYCLINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8927000A GB2238540B (en) 1989-11-29 1989-11-29 13-deoxy-4'-deoxy-4'-iodoanthracyclines

Publications (3)

Publication Number Publication Date
GB8927000D0 GB8927000D0 (en) 1990-01-17
GB2238540A GB2238540A (en) 1991-06-05
GB2238540B true GB2238540B (en) 1993-09-29

Family

ID=10667130

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8927000A Expired - Fee Related GB2238540B (en) 1989-11-29 1989-11-29 13-deoxy-4'-deoxy-4'-iodoanthracyclines

Country Status (4)

Country Link
JP (1) JPH03190892A (en)
DE (1) DE4037693A1 (en)
GB (1) GB2238540B (en)
IT (1) IT1245851B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them
US7244829B2 (en) * 2004-11-08 2007-07-17 Gem Pharmaceuticals, Llc Compositions and processes for preparing 13-deoxy-anthracyclines

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048967A1 (en) * 1980-09-29 1982-04-07 FARMITALIA CARLO ERBA S.p.A. Process for the production of 4'-deoxydaunorubicin and 4'-deoxydoxorubicin, and 4'-epi-4'-trifluoromethyl-sulphonyloxy-N-trifluoroacetyl daunorubicin
GB2118540A (en) * 1982-04-19 1983-11-02 Erba Farmitalia Anthracycline glycosides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048967A1 (en) * 1980-09-29 1982-04-07 FARMITALIA CARLO ERBA S.p.A. Process for the production of 4'-deoxydaunorubicin and 4'-deoxydoxorubicin, and 4'-epi-4'-trifluoromethyl-sulphonyloxy-N-trifluoroacetyl daunorubicin
GB2118540A (en) * 1982-04-19 1983-11-02 Erba Farmitalia Anthracycline glycosides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. Med. Chem. 21 280 to 283 (1978) *

Also Published As

Publication number Publication date
DE4037693A1 (en) 1991-06-06
GB2238540A (en) 1991-06-05
IT1245851B (en) 1994-10-25
IT9022047A0 (en) 1990-11-14
IT9022047A1 (en) 1992-05-14
GB8927000D0 (en) 1990-01-17
JPH03190892A (en) 1991-08-20

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20051129