CA2870087C - Substituted isoquinolin-1(2h)-one compounds and their use as phosphoinositide 3-kinase (pi3k) inhibitors - Google Patents

Substituted isoquinolin-1(2h)-one compounds and their use as phosphoinositide 3-kinase (pi3k) inhibitors Download PDF

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CA2870087C
CA2870087C CA2870087A CA2870087A CA2870087C CA 2870087 C CA2870087 C CA 2870087C CA 2870087 A CA2870087 A CA 2870087A CA 2870087 A CA2870087 A CA 2870087A CA 2870087 C CA2870087 C CA 2870087C
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compound
alkyl
heteroaryl
substituted
aryl
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French (fr)
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CA2870087A1 (en
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Alfredo C. Castro
Katrina Chan
Catherine A. Evans
Somarajannair Janardanannair
Andre Lescarbeau
Liansheng Li
Tao Liu
Yi Liu
Pingda Ren
Daniel A. Snyder
Martin R. Tremblay
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TWELVE THERAPEUTICS, INC.
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Infinity Pharmaceuticals Inc
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CA2870087A 2012-04-10 2013-04-03 Substituted isoquinolin-1(2h)-one compounds and their use as phosphoinositide 3-kinase (pi3k) inhibitors Active CA2870087C (en)

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Application Number Priority Date Filing Date Title
US201261622259P 2012-04-10 2012-04-10
US61/622,259 2012-04-10
US201261713404P 2012-10-12 2012-10-12
US61/713,404 2012-10-12
PCT/US2013/035069 WO2013154878A1 (en) 2012-04-10 2013-04-03 Heterocyclic compounds and uses thereof

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CA2870087A1 CA2870087A1 (en) 2013-10-17
CA2870087C true CA2870087C (en) 2021-02-02

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US (3) US8940742B2 (enExample)
EP (1) EP2836487B1 (enExample)
JP (1) JP6309505B2 (enExample)
CN (1) CN104703979B (enExample)
AU (1) AU2013205238B2 (enExample)
CA (1) CA2870087C (enExample)
HK (1) HK1207069A1 (enExample)
WO (1) WO2013154878A1 (enExample)

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Publication number Priority date Publication date Assignee Title
RS55940B1 (sr) 2005-12-28 2017-09-29 Vertex Pharma Čvrsti oblici n-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksohinolin-3-karboksamida
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
CN104926815B (zh) 2008-01-04 2017-11-03 英特利凯恩有限责任公司 某些化学实体、组合物和方法
TWI674262B (zh) 2011-01-10 2019-10-11 美商英菲尼提製藥股份有限公司 製備異喹啉酮之方法及異喹啉酮之固體形式
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