CA1230186A - Cross-linked gels of hyaluronic acid and products containing such gels - Google Patents

Cross-linked gels of hyaluronic acid and products containing such gels

Info

Publication number
CA1230186A
CA1230186A CA000481055A CA481055A CA1230186A CA 1230186 A CA1230186 A CA 1230186A CA 000481055 A CA000481055 A CA 000481055A CA 481055 A CA481055 A CA 481055A CA 1230186 A CA1230186 A CA 1230186A
Authority
CA
Canada
Prior art keywords
cross
sodium hyaluronate
weight
gel
hyaluronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000481055A
Other languages
English (en)
French (fr)
Inventor
Endre A. Balazs
Adolf Leshchiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomatrix Inc
Original Assignee
Biomatrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomatrix Inc filed Critical Biomatrix Inc
Application granted granted Critical
Publication of CA1230186A publication Critical patent/CA1230186A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CA000481055A 1984-12-06 1985-05-08 Cross-linked gels of hyaluronic acid and products containing such gels Expired CA1230186A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/678,895 US4582865A (en) 1984-12-06 1984-12-06 Cross-linked gels of hyaluronic acid and products containing such gels
US678,895 1991-03-28

Publications (1)

Publication Number Publication Date
CA1230186A true CA1230186A (en) 1987-12-08

Family

ID=24724742

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000481055A Expired CA1230186A (en) 1984-12-06 1985-05-08 Cross-linked gels of hyaluronic acid and products containing such gels

Country Status (9)

Country Link
US (1) US4582865A (en:Method)
JP (2) JPS61138601A (en:Method)
AU (2) AU569157B2 (en:Method)
CA (1) CA1230186A (en:Method)
DE (2) DE3520008A1 (en:Method)
FR (1) FR2574414B1 (en:Method)
GB (4) GB2168067B (en:Method)
IT (1) IT1187737B (en:Method)
SE (2) SE460792B (en:Method)

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JPH02138346A (ja) 1990-05-28
GB2168067A (en) 1986-06-11
GB2181148A (en) 1987-04-15
US4582865A (en) 1986-04-15
AU7217387A (en) 1987-08-27
GB8618720D0 (en) 1986-09-10
GB2181148B (en) 1989-06-07
SE8503486L (sv) 1986-06-07
DE3520008C2 (en:Method) 1991-10-10
SE8503486D0 (sv) 1985-07-15
GB2181147A (en) 1987-04-15
SE8901672D0 (sv) 1989-05-10
AU572419B2 (en) 1988-05-05
JPS61138601A (ja) 1986-06-26
JPH0637575B2 (ja) 1994-05-18
DE3520008A1 (de) 1986-06-19
AU4304585A (en) 1986-06-12
IT8522089A0 (it) 1985-09-09
SE460792B (sv) 1989-11-20
DE3546811C2 (en:Method) 1993-09-02
GB2205848A (en) 1988-12-21
AU569157B2 (en) 1988-01-21
GB8817772D0 (en) 1988-09-01
JPH0430961B2 (en:Method) 1992-05-25
GB2168067B (en) 1989-06-07
FR2574414B1 (fr) 1987-07-03
FR2574414A1 (fr) 1986-06-13
GB8618719D0 (en) 1986-09-10
GB8512072D0 (en) 1985-06-19
IT1187737B (it) 1987-12-23
SE501828C2 (sv) 1995-05-22
GB2181147B (en) 1989-06-07
GB2205848B (en) 1989-05-24
SE8901672L (sv) 1989-05-10

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