AU2015292744C1 - Treatment of cancer using humanized anti-BCMA chimeric antigen receptor - Google Patents

Treatment of cancer using humanized anti-BCMA chimeric antigen receptor Download PDF

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AU2015292744C1
AU2015292744C1 AU2015292744A AU2015292744A AU2015292744C1 AU 2015292744 C1 AU2015292744 C1 AU 2015292744C1 AU 2015292744 A AU2015292744 A AU 2015292744A AU 2015292744 A AU2015292744 A AU 2015292744A AU 2015292744 C1 AU2015292744 C1 AU 2015292744C1
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seq
amino acid
acid sequence
bcma
cell
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AU2015292744A1 (en
AU2015292744B2 (en
AU2015292744A8 (en
Inventor
Jennifer BROGDON
Eugene Choi
Hilmar Ebersbach
David Glass
Heather Huet
Carl H. June
Joan Mannick
Michael C. Milone
Leon Murphy
Gabriela PLESA
Celeste RICHARDSON
Marco RUELLA
Reshma Singh
Yongqiang Wang
Qilong WU
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Novartis AG
University of Pennsylvania Penn
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Novartis AG
University of Pennsylvania Penn
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Priority to AU2020202726A priority Critical patent/AU2020202726A1/en
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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AU2015292744A 2014-07-21 2015-07-21 Treatment of cancer using humanized anti-BCMA chimeric antigen receptor Active AU2015292744C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2020202726A AU2020202726A1 (en) 2014-07-21 2020-04-23 Treatment of cancer using humanized anti-BCMA chimeric antigen receptor

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN2014082586 2014-07-21
CNPCT/CN2014/082586 2014-07-21
CN2014090501 2014-11-06
CNPCT/CN2014/090501 2014-11-06
PCT/US2015/041378 WO2016014565A2 (en) 2014-07-21 2015-07-21 Treatment of cancer using humanized anti-bcma chimeric antigen receptor

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AU2020202726A Division AU2020202726A1 (en) 2014-07-21 2020-04-23 Treatment of cancer using humanized anti-BCMA chimeric antigen receptor

Publications (4)

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AU2015292744A1 AU2015292744A1 (en) 2017-02-02
AU2015292744A8 AU2015292744A8 (en) 2017-03-09
AU2015292744B2 AU2015292744B2 (en) 2020-01-30
AU2015292744C1 true AU2015292744C1 (en) 2021-01-21

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AU2015292744A Active AU2015292744C1 (en) 2014-07-21 2015-07-21 Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
AU2020202726A Abandoned AU2020202726A1 (en) 2014-07-21 2020-04-23 Treatment of cancer using humanized anti-BCMA chimeric antigen receptor

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US (3) US10174095B2 (https=)
EP (1) EP3172237A2 (https=)
JP (2) JP7054622B2 (https=)
KR (1) KR102612313B1 (https=)
CN (1) CN106687483B (https=)
AU (2) AU2015292744C1 (https=)
BR (1) BR112017001183A2 (https=)
CO (1) CO2017000507A2 (https=)
IL (1) IL250043B (https=)
MX (1) MX2017001011A (https=)
MY (1) MY181834A (https=)
RU (1) RU2751660C2 (https=)
SG (1) SG11201700476VA (https=)
TW (1) TWI750110B (https=)
WO (1) WO2016014565A2 (https=)

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