MX2018005274A - Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t. - Google Patents
Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t.Info
- Publication number
- MX2018005274A MX2018005274A MX2018005274A MX2018005274A MX2018005274A MX 2018005274 A MX2018005274 A MX 2018005274A MX 2018005274 A MX2018005274 A MX 2018005274A MX 2018005274 A MX2018005274 A MX 2018005274A MX 2018005274 A MX2018005274 A MX 2018005274A
- Authority
- MX
- Mexico
- Prior art keywords
- cells
- methods
- generating
- immunotherapeutic
- stem
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 210000000130 stem cell Anatomy 0.000 title abstract 2
- 230000001024 immunotherapeutic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 239000012679 serum free medium Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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- A61K39/46—Cellular immunotherapy
- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4631—Chimeric Antigen Receptors [CAR]
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- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4632—T-cell receptors [TCR]; antibody T-cell receptor constructs
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- A—HUMAN NECESSITIES
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Abstract
Se proporcionan métodos y una composición para la producción de células-T. También se proporcionan métodos terapéuticos usando las células T diseñadas; por ejemplo, en ciertos aspectos los métodos incluyen preparar composiciones de cultivos celulares tridimensionales que comprenden células estromales y células madre o progenitoras hematopoyéticas en un medio libre de suero para producir células T.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US201562248931P | 2015-10-30 | 2015-10-30 | |
US201562265204P | 2015-12-09 | 2015-12-09 | |
US201662359456P | 2016-07-07 | 2016-07-07 | |
PCT/US2016/059375 WO2017075389A1 (en) | 2015-10-30 | 2016-10-28 | Methods of generating t-cells from stem cells and immunotherapeutic methods using the t-cells |
Publications (1)
Publication Number | Publication Date |
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MX2018005274A true MX2018005274A (es) | 2019-09-19 |
Family
ID=58631163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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MX2018005274A MX2018005274A (es) | 2015-10-30 | 2016-10-28 | Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t. |
Country Status (13)
Country | Link |
---|---|
US (2) | US11154573B2 (es) |
EP (1) | EP3368660A4 (es) |
JP (2) | JP6983771B2 (es) |
KR (1) | KR20180092951A (es) |
CN (1) | CN108463548B (es) |
AU (2) | AU2016343682A1 (es) |
BR (1) | BR112018008648A2 (es) |
CA (1) | CA3003145A1 (es) |
IL (1) | IL258899B2 (es) |
MX (1) | MX2018005274A (es) |
SG (1) | SG11201803419PA (es) |
TW (2) | TW202344686A (es) |
WO (1) | WO2017075389A1 (es) |
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- 2016-10-28 US US15/772,224 patent/US11154573B2/en active Active
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- 2016-10-28 JP JP2018522655A patent/JP6983771B2/ja active Active
- 2016-10-28 SG SG11201803419PA patent/SG11201803419PA/en unknown
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US11154573B2 (en) | 2021-10-26 |
CA3003145A1 (en) | 2017-05-04 |
NZ742915A (en) | 2024-02-23 |
US20220096553A1 (en) | 2022-03-31 |
JP6983771B2 (ja) | 2021-12-17 |
JP7402211B2 (ja) | 2023-12-20 |
KR20180092951A (ko) | 2018-08-20 |
AU2023202195A1 (en) | 2023-05-11 |
TW201730334A (zh) | 2017-09-01 |
BR112018008648A2 (pt) | 2018-11-27 |
WO2017075389A1 (en) | 2017-05-04 |
TWI812584B (zh) | 2023-08-21 |
TW202344686A (zh) | 2023-11-16 |
JP2022033812A (ja) | 2022-03-02 |
IL258899B2 (en) | 2024-03-01 |
CN108463548B (zh) | 2023-04-18 |
WO2017075389A8 (en) | 2018-05-24 |
IL258899A (en) | 2018-06-28 |
JP2018533364A (ja) | 2018-11-15 |
CN108463548A (zh) | 2018-08-28 |
EP3368660A4 (en) | 2019-04-24 |
US20190231817A1 (en) | 2019-08-01 |
IL258899B1 (en) | 2023-11-01 |
SG11201803419PA (en) | 2018-05-30 |
EP3368660A1 (en) | 2018-09-05 |
AU2016343682A1 (en) | 2018-06-14 |
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