MX363690B - Expansión de celulas madre adultas in vitro. - Google Patents
Expansión de celulas madre adultas in vitro.Info
- Publication number
- MX363690B MX363690B MX2015012168A MX2015012168A MX363690B MX 363690 B MX363690 B MX 363690B MX 2015012168 A MX2015012168 A MX 2015012168A MX 2015012168 A MX2015012168 A MX 2015012168A MX 363690 B MX363690 B MX 363690B
- Authority
- MX
- Mexico
- Prior art keywords
- stem cells
- adult stem
- vitro
- expansion
- methods
- Prior art date
Links
- 210000004504 adult stem cell Anatomy 0.000 title abstract 2
- 238000000338 in vitro Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/145—Thrombopoietin [TPO]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2303—Interleukin-3 (IL-3)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2306—Interleukin-6 (IL-6)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/48—Regulators of apoptosis
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La presente invención se refiere a métodos para manipular y expandir poblaciones de células madre, incluidas células madre adultas, células producidas por dichos métodos, y varios constructos de proteína relacionados con estas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361776422P | 2013-03-11 | 2013-03-11 | |
| US13/795,659 US9365825B2 (en) | 2013-03-11 | 2013-03-12 | Expansion of adult stem cells in vitro |
| PCT/US2014/022977 WO2014164606A1 (en) | 2013-03-11 | 2014-03-11 | Expansion of adult stem cells in vitro |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012168A MX2015012168A (es) | 2016-05-18 |
| MX363690B true MX363690B (es) | 2019-03-29 |
Family
ID=51658913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012168A MX363690B (es) | 2013-03-11 | 2014-03-11 | Expansión de celulas madre adultas in vitro. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9365825B2 (es) |
| EP (1) | EP2970885A4 (es) |
| JP (2) | JP6573868B2 (es) |
| CN (2) | CN105209604B (es) |
| AU (2) | AU2014249202B2 (es) |
| CA (1) | CA2905296A1 (es) |
| HK (1) | HK1219505A1 (es) |
| IL (2) | IL241299A (es) |
| MX (1) | MX363690B (es) |
| SG (2) | SG10201607825XA (es) |
| WO (1) | WO2014164606A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101441693B1 (ko) | 2005-10-18 | 2014-09-25 | 내셔날 쥬이쉬 헬스 | 조건부 불멸화 장기 줄기 세포 및 상기 세포의 제조 및사용 방법 |
| SG190661A1 (en) | 2008-05-16 | 2013-06-28 | Taiga Biotechnologies Inc | Antibodies and processes for preparing the same |
| JP5812861B2 (ja) | 2008-08-28 | 2015-11-17 | タイガ バイオテクノロジーズ,インク. | Mycの修飾物質、該mycの修飾物質を使用する方法、およびmycを調節する薬剤を同定する方法 |
| SG11201500429QA (en) * | 2012-07-20 | 2015-03-30 | Taiga Biotechnologies Inc | Enhanced reconstitution and autoreconstitution of the hematopoietic compartment |
| US10272115B2 (en) | 2013-03-11 | 2019-04-30 | Taiga Biotechnologies, Inc. | Production and use of red blood cells |
| US9365825B2 (en) * | 2013-03-11 | 2016-06-14 | Taiga Biotechnologies, Inc. | Expansion of adult stem cells in vitro |
| US9870425B2 (en) * | 2014-02-27 | 2018-01-16 | Excalibur Ip, Llc | Localized selectable location and/or time for search queries and/or search query results |
| AU2017367730A1 (en) | 2016-12-02 | 2019-06-06 | Taiga Biotechnologies, Inc. | Nanoparticle formulations |
| EP3661953A4 (en) * | 2017-08-03 | 2021-04-14 | Taiga Biotechnologies, Inc. | CANCER TREATMENT METHODS AND COMPOSITIONS |
| US10149898B2 (en) | 2017-08-03 | 2018-12-11 | Taiga Biotechnologies, Inc. | Methods and compositions for the treatment of melanoma |
| CN107858330B (zh) * | 2017-11-20 | 2021-08-27 | 上海中医药大学 | 一种小鼠骨髓造血干/祖细胞体外衰老细胞模型的建立方法 |
| WO2020210231A1 (en) | 2019-04-08 | 2020-10-15 | Taiga Biotechnologies, Inc. | Compositions and methods for the cry opreservation of immune cells |
| CN114072166A (zh) | 2019-05-14 | 2022-02-18 | 泰加生物工艺学公司 | 用于治疗t细胞耗竭的组合物和方法 |
| JP7197538B2 (ja) * | 2020-07-03 | 2022-12-27 | タイガ バイオテクノロジーズ,インク. | メラノーマの処置のための方法および組成物 |
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2013
- 2013-03-12 US US13/795,659 patent/US9365825B2/en active Active
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- 2014-03-11 WO PCT/US2014/022977 patent/WO2014164606A1/en not_active Ceased
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| Publication number | Publication date |
|---|---|
| AU2014249202A1 (en) | 2015-10-29 |
| AU2014249202B2 (en) | 2016-03-10 |
| EP2970885A4 (en) | 2017-01-25 |
| US20160355785A1 (en) | 2016-12-08 |
| US9365825B2 (en) | 2016-06-14 |
| JP6573868B2 (ja) | 2019-09-11 |
| CA2905296A1 (en) | 2014-10-09 |
| HK1219505A1 (zh) | 2017-04-07 |
| US20140273212A1 (en) | 2014-09-18 |
| MX2015012168A (es) | 2016-05-18 |
| IL247798B (en) | 2019-03-31 |
| CN105209604A (zh) | 2015-12-30 |
| AU2016203892B2 (en) | 2018-04-05 |
| CN108504626B (zh) | 2022-05-24 |
| CN108504626A (zh) | 2018-09-07 |
| IL241299A (en) | 2016-10-31 |
| JP2018088936A (ja) | 2018-06-14 |
| US10087420B2 (en) | 2018-10-02 |
| SG10201607825XA (en) | 2016-11-29 |
| JP6647334B2 (ja) | 2020-02-14 |
| JP2016510996A (ja) | 2016-04-14 |
| IL241299A0 (en) | 2015-11-30 |
| EP2970885A1 (en) | 2016-01-20 |
| SG11201507238TA (en) | 2015-10-29 |
| WO2014164606A1 (en) | 2014-10-09 |
| CN105209604B (zh) | 2018-04-24 |
| AU2016203892A1 (en) | 2016-06-30 |
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