FR2722208B1 - Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique - Google Patents

Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique

Info

Publication number
FR2722208B1
FR2722208B1 FR9408300A FR9408300A FR2722208B1 FR 2722208 B1 FR2722208 B1 FR 2722208B1 FR 9408300 A FR9408300 A FR 9408300A FR 9408300 A FR9408300 A FR 9408300A FR 2722208 B1 FR2722208 B1 FR 2722208B1
Authority
FR
France
Prior art keywords
vector containing
therapeutic use
entry site
internal ribosome
ribosome entry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9408300A
Other languages
English (en)
Other versions
FR2722208A1 (fr
Inventor
Clarisse Berlioz
Sabdrine Jacquemoud
Christophe Torrent
Jean Luc Darlix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9408300A priority Critical patent/FR2722208B1/fr
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to PCT/FR1995/000894 priority patent/WO1996001324A2/fr
Priority to AU29295/95A priority patent/AU707874B2/en
Priority to EP95925007A priority patent/EP0769062A2/fr
Priority to CA002194155A priority patent/CA2194155A1/fr
Priority to US08/600,999 priority patent/US5925565A/en
Priority to JP8503707A priority patent/JPH10503644A/ja
Publication of FR2722208A1 publication Critical patent/FR2722208A1/fr
Application granted granted Critical
Publication of FR2722208B1 publication Critical patent/FR2722208B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13051—Methods of production or purification of viral material
    • C12N2740/13052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/802—Virus-based particle
    • Y10S977/803—Containing biological material in its interior
    • Y10S977/804—Containing nucleic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92—Detection of biochemical
FR9408300A 1994-07-05 1994-07-05 Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique Expired - Fee Related FR2722208B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR9408300A FR2722208B1 (fr) 1994-07-05 1994-07-05 Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
AU29295/95A AU707874B2 (en) 1994-07-05 1995-07-05 New internal ribosome entry site, vector containing it and therapeutical use
EP95925007A EP0769062A2 (fr) 1994-07-05 1995-07-05 Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
CA002194155A CA2194155A1 (fr) 1994-07-05 1995-07-05 Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
PCT/FR1995/000894 WO1996001324A2 (fr) 1994-07-05 1995-07-05 Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
US08/600,999 US5925565A (en) 1994-07-05 1995-07-05 Internal ribosome entry site, vector containing it and therapeutic use
JP8503707A JPH10503644A (ja) 1994-07-05 1995-07-05 新規な内部リボソーム侵入部位、これを含むベクター、および治療への使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9408300A FR2722208B1 (fr) 1994-07-05 1994-07-05 Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique

Publications (2)

Publication Number Publication Date
FR2722208A1 FR2722208A1 (fr) 1996-01-12
FR2722208B1 true FR2722208B1 (fr) 1996-10-04

Family

ID=9465025

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9408300A Expired - Fee Related FR2722208B1 (fr) 1994-07-05 1994-07-05 Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique

Country Status (7)

Country Link
US (1) US5925565A (fr)
EP (1) EP0769062A2 (fr)
JP (1) JPH10503644A (fr)
AU (1) AU707874B2 (fr)
CA (1) CA2194155A1 (fr)
FR (1) FR2722208B1 (fr)
WO (1) WO1996001324A2 (fr)

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