NZ581803A - Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile - Google Patents

Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile

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Publication number
NZ581803A
NZ581803A NZ581803A NZ58180308A NZ581803A NZ 581803 A NZ581803 A NZ 581803A NZ 581803 A NZ581803 A NZ 581803A NZ 58180308 A NZ58180308 A NZ 58180308A NZ 581803 A NZ581803 A NZ 581803A
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NZ
New Zealand
Prior art keywords
disease
salt
cancer
patient
medicament
Prior art date
Application number
NZ581803A
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English (en)
Inventor
James D Rodgers
Original Assignee
Incyte Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40029273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ581803(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of NZ581803A publication Critical patent/NZ581803A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/20—Pills, tablets, discs, rods
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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NZ581803A 2007-06-13 2008-06-12 Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile NZ581803A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94370507P 2007-06-13 2007-06-13
PCT/US2008/066662 WO2008157208A2 (en) 2007-06-13 2008-06-12 Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile

Publications (1)

Publication Number Publication Date
NZ581803A true NZ581803A (en) 2012-05-25

Family

ID=40029273

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ581803A NZ581803A (en) 2007-06-13 2008-06-12 Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile

Country Status (41)

Country Link
US (10) US20080312259A1 (https=)
EP (6) EP3070090B1 (https=)
JP (1) JP5475653B2 (https=)
KR (2) KR20150036210A (https=)
CN (2) CN103524509B (https=)
AU (1) AU2008266183B2 (https=)
BR (1) BRPI0814254B8 (https=)
CA (1) CA2689663C (https=)
CO (1) CO6251256A2 (https=)
CR (1) CR11151A (https=)
CU (2) CU24179B1 (https=)
CY (3) CY1115145T1 (https=)
DK (3) DK2740731T3 (https=)
DO (1) DOP2009000280A (https=)
EA (1) EA019784B1 (https=)
EC (1) ECSP099802A (https=)
ES (4) ES2903444T3 (https=)
GE (1) GEP20125533B (https=)
GT (1) GT200900314A (https=)
HR (3) HRP20140541T4 (https=)
HU (2) HUE043732T2 (https=)
IL (5) IL202524A (https=)
LT (1) LT3070090T (https=)
MA (1) MA31517B1 (https=)
ME (1) ME00960B (https=)
MX (2) MX342814B (https=)
MY (1) MY154969A (https=)
NI (1) NI200900216A (https=)
NO (1) NO2019025I1 (https=)
NZ (1) NZ581803A (https=)
PL (3) PL2173752T5 (https=)
PT (2) PT2173752E (https=)
RS (3) RS53245B2 (https=)
SG (3) SG10201509887UA (https=)
SI (3) SI3070090T1 (https=)
SM (1) SMP201000002B (https=)
TN (1) TN2009000514A1 (https=)
TR (1) TR201903488T4 (https=)
UA (1) UA99467C2 (https=)
WO (1) WO2008157208A2 (https=)
ZA (1) ZA200908826B (https=)

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WO2009064835A1 (en) * 2007-11-16 2009-05-22 Incyte Corporation 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors
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PT3354652T (pt) 2010-03-10 2020-07-20 Incyte Holdings Corp Derivados de piperidin-4-ilazetidina como inibidores de jak1
RS54824B1 (sr) 2010-05-21 2016-10-31 Incyte Holdings Corp Topikalna formulacija za inhibiciju jak-a
WO2012030948A1 (en) 2010-09-01 2012-03-08 Ambit Biosciences Corporation Quinazoline compounds and methods of use thereof
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