SI2740731T1 - Kristalinične soli inhibitorja za janus kinazo (r)-3-(4-(7h-pirolo(2,3-d)pirimidin-4-il)-1h-pirazol-1-il)-3-ciklopen tilpropannitrila - Google Patents

Kristalinične soli inhibitorja za janus kinazo (r)-3-(4-(7h-pirolo(2,3-d)pirimidin-4-il)-1h-pirazol-1-il)-3-ciklopen tilpropannitrila

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Publication number
SI2740731T1
SI2740731T1 SI200831621A SI200831621A SI2740731T1 SI 2740731 T1 SI2740731 T1 SI 2740731T1 SI 200831621 A SI200831621 A SI 200831621A SI 200831621 A SI200831621 A SI 200831621A SI 2740731 T1 SI2740731 T1 SI 2740731T1
Authority
SI
Slovenia
Prior art keywords
cyclopentylpropanenitrile
pyrrolo
pyrazol
pyrimidin
kinase inhibitor
Prior art date
Application number
SI200831621A
Other languages
English (en)
Inventor
Hui-Yin Li
James D. Rodgers
Original Assignee
Incyte Holdings Coroporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40029273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2740731(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Holdings Coroporation filed Critical Incyte Holdings Coroporation
Publication of SI2740731T1 publication Critical patent/SI2740731T1/sl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
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SI200831621A 2007-06-13 2008-06-12 Kristalinične soli inhibitorja za janus kinazo (r)-3-(4-(7h-pirolo(2,3-d)pirimidin-4-il)-1h-pirazol-1-il)-3-ciklopen tilpropannitrila SI2740731T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94370507P 2007-06-13 2007-06-13
EP13198120.1A EP2740731B1 (en) 2007-06-13 2008-06-12 Crystalline salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile

Publications (1)

Publication Number Publication Date
SI2740731T1 true SI2740731T1 (sl) 2016-07-29

Family

ID=40029273

Family Applications (3)

Application Number Title Priority Date Filing Date
SI200831621A SI2740731T1 (sl) 2007-06-13 2008-06-12 Kristalinične soli inhibitorja za janus kinazo (r)-3-(4-(7h-pirolo(2,3-d)pirimidin-4-il)-1h-pirazol-1-il)-3-ciklopen tilpropannitrila
SI200832042T SI3070090T1 (sl) 2007-06-13 2008-06-12 Uporaba soli zaviralca Janus kinaze (R)-3-(4-(7H-pirolo (2,3-D)pirimidin-4-il)-1H-pirazol-1-il)-3-ciklopentilpropannitrila
SI200831217T SI2173752T2 (sl) 2007-06-13 2008-06-12 Soli inhibitorja za janus kinazo (r)-3-(4-(7h-pirolo(2,3-d)pirimidin-4- il)-1h-pirazol-1-il)-3-ciklopentilpropannitrila

Family Applications After (2)

Application Number Title Priority Date Filing Date
SI200832042T SI3070090T1 (sl) 2007-06-13 2008-06-12 Uporaba soli zaviralca Janus kinaze (R)-3-(4-(7H-pirolo (2,3-D)pirimidin-4-il)-1H-pirazol-1-il)-3-ciklopentilpropannitrila
SI200831217T SI2173752T2 (sl) 2007-06-13 2008-06-12 Soli inhibitorja za janus kinazo (r)-3-(4-(7h-pirolo(2,3-d)pirimidin-4- il)-1h-pirazol-1-il)-3-ciklopentilpropannitrila

Country Status (42)

Country Link
US (10) US20080312259A1 (sl)
EP (5) EP4011883A1 (sl)
JP (1) JP5475653B2 (sl)
KR (2) KR101549876B1 (sl)
CN (2) CN101932582B (sl)
AU (1) AU2008266183B2 (sl)
BR (1) BRPI0814254B8 (sl)
CA (1) CA2689663C (sl)
CO (1) CO6251256A2 (sl)
CR (1) CR11151A (sl)
CU (2) CU24179B1 (sl)
CY (3) CY1115145T1 (sl)
DK (3) DK2740731T3 (sl)
DO (1) DOP2009000280A (sl)
EA (1) EA019784B1 (sl)
EC (1) ECSP099802A (sl)
ES (4) ES2575797T3 (sl)
GE (1) GEP20125533B (sl)
GT (1) GT200900314A (sl)
HK (2) HK1143161A1 (sl)
HR (3) HRP20140541T4 (sl)
HU (2) HUE043732T2 (sl)
IL (5) IL202524A (sl)
LT (1) LT3070090T (sl)
MA (1) MA31517B1 (sl)
ME (1) ME00960B (sl)
MX (2) MX2009013402A (sl)
MY (1) MY154969A (sl)
NI (1) NI200900216A (sl)
NO (1) NO2019025I1 (sl)
NZ (1) NZ581803A (sl)
PL (3) PL2740731T3 (sl)
PT (2) PT3070090T (sl)
RS (3) RS58449B1 (sl)
SG (3) SG10201509887UA (sl)
SI (3) SI2740731T1 (sl)
SM (1) SMP201000002B (sl)
TN (1) TN2009000514A1 (sl)
TR (1) TR201903488T4 (sl)
UA (1) UA99467C2 (sl)
WO (1) WO2008157208A2 (sl)
ZA (1) ZA200908826B (sl)

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PT2288610T (pt) 2008-03-11 2016-10-17 Incyte Holdings Corp Derivados de azetidina e de ciclobutano como inibidores de jak
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KR101771401B1 (ko) 2009-05-22 2017-08-25 인사이트 홀딩스 코포레이션 야누스 키나제 억제제로서 피라졸­４­일­피롤로［２,３­ｄ］피리미딘 및 피롤­３­일­피롤로［２,３­ｄ］피리미딘의 Ｎ­(헤테로)아릴­피롤리딘 유도체
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JP5901634B2 (ja) 2010-09-01 2016-04-13 アムビト ビオスシエンセス コルポラチオン キナゾリン化合物及びその使用方法
WO2012061537A2 (en) * 2010-11-02 2012-05-10 The Trustees Of Columbia University In The City Of New York Methods for treating hair loss disorders
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