MX2009013402A - Sales de inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]piri midin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo. - Google Patents
Sales de inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]piri midin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo.Info
- Publication number
- MX2009013402A MX2009013402A MX2009013402A MX2009013402A MX2009013402A MX 2009013402 A MX2009013402 A MX 2009013402A MX 2009013402 A MX2009013402 A MX 2009013402A MX 2009013402 A MX2009013402 A MX 2009013402A MX 2009013402 A MX2009013402 A MX 2009013402A
- Authority
- MX
- Mexico
- Prior art keywords
- pyrrolo
- pyrazol
- cyclopentylpropanenitrile
- rimidin
- salts
- Prior art date
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07—ORGANIC CHEMISTRY
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C07B2200/07—Optical isomers
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- C07—ORGANIC CHEMISTRY
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- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Abstract
La presente invención proporciona formas de sal de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-cic lopentilpropanitrilo que son útiles en la modulación de la actividad de la cinasa Janus que incluye, por ejemplo, enfermedades relacionadas con el sistema inmunitario, trastornos de la piel, trastornos proliferativos mieloides, cáncer, y otras enfermedades.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94370507P | 2007-06-13 | 2007-06-13 | |
PCT/US2008/066662 WO2008157208A2 (en) | 2007-06-13 | 2008-06-12 | Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009013402A true MX2009013402A (es) | 2010-02-24 |
Family
ID=40029273
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009013402A MX2009013402A (es) | 2007-06-13 | 2008-06-12 | Sales de inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]piri midin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo. |
MX2013005828A MX342814B (es) | 2007-06-13 | 2008-06-12 | Sales de inhibidor de janus cinasa (r)-3-(4-7h-pirrolo[2,3-d]pirim idin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013005828A MX342814B (es) | 2007-06-13 | 2008-06-12 | Sales de inhibidor de janus cinasa (r)-3-(4-7h-pirrolo[2,3-d]pirim idin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanitrilo. |
Country Status (42)
Families Citing this family (115)
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PL2474545T3 (pl) | 2005-12-13 | 2017-04-28 | Incyte Holdings Corporation | Podstawione heteroarylem pirolo[2,3-b]pirydyny i pirolo[2,3-b]pirymidyny jako inhibitory kinazy Janusowej |
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PL2173752T5 (pl) | 2007-06-13 | 2022-12-05 | Incyte Holdings Corporation | Sole (r)-3-(4-(7h-pirolo(2,3-d)pirymidyn-4-ylo)-1h-pirazol-1-ilo)-3-cyklopentylopropanonitrylu inhibitora kinazy janusowej |
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