DE69308573T2 - Bispezifische immunoadhesine - Google Patents

Bispezifische immunoadhesine

Info

Publication number
DE69308573T2
DE69308573T2 DE69308573T DE69308573T DE69308573T2 DE 69308573 T2 DE69308573 T2 DE 69308573T2 DE 69308573 T DE69308573 T DE 69308573T DE 69308573 T DE69308573 T DE 69308573T DE 69308573 T2 DE69308573 T2 DE 69308573T2
Authority
DE
Germany
Prior art keywords
immunoadhesine
specific
specificity
heavy chain
immunoglobulin heavy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69308573T
Other languages
English (en)
Other versions
DE69308573D1 (de
Inventor
Avi Ashkenazi
Steven Chamow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DE69308573D1 publication Critical patent/DE69308573D1/de
Application granted granted Critical
Publication of DE69308573T2 publication Critical patent/DE69308573T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • External Artificial Organs (AREA)
DE69308573T 1992-08-17 1993-08-17 Bispezifische immunoadhesine Expired - Lifetime DE69308573T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93181192A 1992-08-17 1992-08-17
PCT/US1993/007783 WO1994004690A1 (en) 1992-08-17 1993-08-17 Bispecific immunoadhesins

Publications (2)

Publication Number Publication Date
DE69308573D1 DE69308573D1 (de) 1997-04-10
DE69308573T2 true DE69308573T2 (de) 1997-08-07

Family

ID=25461393

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69308573T Expired - Lifetime DE69308573T2 (de) 1992-08-17 1993-08-17 Bispezifische immunoadhesine

Country Status (7)

Country Link
EP (1) EP0656064B1 (de)
JP (1) JPH08500017A (de)
AT (1) ATE149570T1 (de)
AU (1) AU668423B2 (de)
CA (1) CA2140280A1 (de)
DE (1) DE69308573T2 (de)
WO (1) WO1994004690A1 (de)

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CA2140280A1 (en) 1994-03-03
EP0656064B1 (de) 1997-03-05
DE69308573D1 (de) 1997-04-10
AU5080193A (en) 1994-03-15
AU668423B2 (en) 1996-05-02
WO1994004690A1 (en) 1994-03-03
ATE149570T1 (de) 1997-03-15
EP0656064A1 (de) 1995-06-07

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