ATE318844T1 - Wachstumsinhibierende agenzien gegen vitamin b12 bindungsstellen von transcobalamin-ii - Google Patents

Wachstumsinhibierende agenzien gegen vitamin b12 bindungsstellen von transcobalamin-ii

Info

Publication number
ATE318844T1
ATE318844T1 AT95934520T AT95934520T ATE318844T1 AT E318844 T1 ATE318844 T1 AT E318844T1 AT 95934520 T AT95934520 T AT 95934520T AT 95934520 T AT95934520 T AT 95934520T AT E318844 T1 ATE318844 T1 AT E318844T1
Authority
AT
Austria
Prior art keywords
transcobalamin
receptor
binding sites
vitamin
inhibiting agents
Prior art date
Application number
AT95934520T
Other languages
English (en)
Inventor
A Charles Morgan Jr
Edward V Quadros
Sheldon P Rothenberg
Original Assignee
Kyto Biopharma Inc
Univ New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/306,504 external-priority patent/US5688504A/en
Application filed by Kyto Biopharma Inc, Univ New York filed Critical Kyto Biopharma Inc
Application granted granted Critical
Publication of ATE318844T1 publication Critical patent/ATE318844T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT95934520T 1994-09-13 1995-09-13 Wachstumsinhibierende agenzien gegen vitamin b12 bindungsstellen von transcobalamin-ii ATE318844T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/306,504 US5688504A (en) 1992-05-08 1994-09-13 Anti-receptor and growth blocking antibodies to the vitamin B12 /transcobalamin II receptor and binding sites
US38152295A 1995-01-31 1995-01-31
US47644095A 1995-06-07 1995-06-07

Publications (1)

Publication Number Publication Date
ATE318844T1 true ATE318844T1 (de) 2006-03-15

Family

ID=27405173

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95934520T ATE318844T1 (de) 1994-09-13 1995-09-13 Wachstumsinhibierende agenzien gegen vitamin b12 bindungsstellen von transcobalamin-ii

Country Status (7)

Country Link
EP (1) EP0783526B1 (de)
JP (1) JPH10508831A (de)
AT (1) ATE318844T1 (de)
AU (1) AU3683395A (de)
CA (1) CA2199940C (de)
DE (1) DE69534818D1 (de)
WO (1) WO1996008515A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7416728B2 (en) 1992-05-08 2008-08-26 Kyto Biopharma, Inc. Growth blocking agents
EP2075256A2 (de) 2002-01-14 2009-07-01 William Herman Gezielte Liganden
US9044461B2 (en) 2006-04-07 2015-06-02 The Research Foundation Of State University Of New York Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
WO2007117657A2 (en) 2006-04-07 2007-10-18 The Research Foundation Of State University Of New York Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
US9120858B2 (en) 2011-07-22 2015-09-01 The Research Foundation Of State University Of New York Antibodies to the B12-transcobalamin receptor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ252559A (en) * 1992-05-08 1996-10-28 Receptagen Corp Antibodies or derivatives thereof to vitamin b12/transcobalamin ii receptor and use in preventing cellular uptake of vitamin b12 and inhibiting cell division

Also Published As

Publication number Publication date
DE69534818D1 (de) 2006-04-27
JPH10508831A (ja) 1998-09-02
EP0783526B1 (de) 2006-03-01
CA2199940C (en) 2011-02-08
WO1996008515A1 (en) 1996-03-21
EP0783526A1 (de) 1997-07-16
CA2199940A1 (en) 1996-03-21
AU3683395A (en) 1996-03-29

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