BRPI9916853B8 - anticorpo monoclonal ou um fragmento de ligação a antígeno do mesmo que se liga especificamente ao antígeno do linfócito t citotóxico 4 (ctla-4) e ácido nucleico - Google Patents

anticorpo monoclonal ou um fragmento de ligação a antígeno do mesmo que se liga especificamente ao antígeno do linfócito t citotóxico 4 (ctla-4) e ácido nucleico

Info

Publication number
BRPI9916853B8
BRPI9916853B8 BRPI9916853A BRPI9916853A BRPI9916853B8 BR PI9916853 B8 BRPI9916853 B8 BR PI9916853B8 BR PI9916853 A BRPI9916853 A BR PI9916853A BR PI9916853 A BRPI9916853 A BR PI9916853A BR PI9916853 B8 BRPI9916853 B8 BR PI9916853B8
Authority
BR
Brazil
Prior art keywords
antigen
ctla
cytotoxic
antibodies
nucleic acid
Prior art date
Application number
BRPI9916853A
Other languages
English (en)
Portuguese (pt)
Inventor
Geoffrey Davis C
Charles Hanson Douglas
Elliot Mueller Eileen
Herbert Hanke Jeffrey
Ramon Corvalan Jose
Joseph Neveu Mark
Christopher Gilmar Steven
Original Assignee
Abgenix Inc
Amgen Fremont Inc
Athletics Merger Sub Inc
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abgenix Inc, Amgen Fremont Inc, Athletics Merger Sub Inc, Pfizer filed Critical Abgenix Inc
Publication of BRPI9916853B1 publication Critical patent/BRPI9916853B1/pt
Publication of BRPI9916853B8 publication Critical patent/BRPI9916853B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BRPI9916853A 1998-12-23 1999-12-23 anticorpo monoclonal ou um fragmento de ligação a antígeno do mesmo que se liga especificamente ao antígeno do linfócito t citotóxico 4 (ctla-4) e ácido nucleico BRPI9916853B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11364798P 1998-12-23 1998-12-23
US60/113,647 1998-12-23
PCT/US1999/030895 WO2000037504A2 (en) 1998-12-23 1999-12-23 Human monoclonal antibodies to ctla-4

Publications (2)

Publication Number Publication Date
BRPI9916853B1 BRPI9916853B1 (pt) 2018-04-24
BRPI9916853B8 true BRPI9916853B8 (pt) 2021-05-25

Family

ID=22350712

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI9916853A BRPI9916853B8 (pt) 1998-12-23 1999-12-23 anticorpo monoclonal ou um fragmento de ligação a antígeno do mesmo que se liga especificamente ao antígeno do linfócito t citotóxico 4 (ctla-4) e ácido nucleico
BR9916853-7A BR9916853A (pt) 1998-12-23 1999-12-23 Anticorpos monoclonais humanos ao ctla-4

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR9916853-7A BR9916853A (pt) 1998-12-23 1999-12-23 Anticorpos monoclonais humanos ao ctla-4

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