BR122024001145A2 - Molécula de anticorpo isolada capaz de se ligar a lag-3, seu método de produção, composição farmacêutica, ácidos nucleicos, vetor de expressão, método para detecção de lag-3 em uma amostra biológica, e uso das referidas molécula de anticorpo e composição - Google Patents

Molécula de anticorpo isolada capaz de se ligar a lag-3, seu método de produção, composição farmacêutica, ácidos nucleicos, vetor de expressão, método para detecção de lag-3 em uma amostra biológica, e uso das referidas molécula de anticorpo e composição Download PDF

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Publication number
BR122024001145A2
BR122024001145A2 BR122024001145-0A BR122024001145A BR122024001145A2 BR 122024001145 A2 BR122024001145 A2 BR 122024001145A2 BR 122024001145 A BR122024001145 A BR 122024001145A BR 122024001145 A2 BR122024001145 A2 BR 122024001145A2
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BR
Brazil
Prior art keywords
seq
bap050
amino acid
acid sequence
inhibitor
Prior art date
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BR122024001145-0A
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English (en)
Portuguese (pt)
Inventor
Frédéric Triebel
Chrystelle Brignone
Walter A. Blattler
Jennifer Marie Mataraza
Catherine Anne Sabatos-Peyton
Hwai Wen Chang
Gerhard Johann Frey
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Novartis Ag
Immutep S.A.S.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52780053&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR122024001145(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Immutep S.A.S. filed Critical Novartis Ag
Priority claimed from BR112016018408-4A external-priority patent/BR112016018408B1/pt
Publication of BR122024001145A2 publication Critical patent/BR122024001145A2/pt

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/54—F(ab')2
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/567—Framework region [FR]
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

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BR122024001145-0A 2014-03-14 2015-03-13 Molécula de anticorpo isolada capaz de se ligar a lag-3, seu método de produção, composição farmacêutica, ácidos nucleicos, vetor de expressão, método para detecção de lag-3 em uma amostra biológica, e uso das referidas molécula de anticorpo e composição BR122024001145A2 (pt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201461953536P 2014-03-14 2014-03-14
US61/953,536 2014-03-14
US201462059690P 2014-10-03 2014-10-03
US62/059,690 2014-10-03
US201462094889P 2014-12-19 2014-12-19
US62/094,889 2014-12-19
PCT/US2015/020474 WO2015138920A1 (en) 2014-03-14 2015-03-13 Antibody molecules to lag-3 and uses thereof
BR112016018408-4A BR112016018408B1 (pt) 2014-03-14 2015-03-13 Molécula de anticorpo isolada capaz de se ligar a lag-3, seu método de produção, composição farmacêutica, ácidos nucleicos, vetor de expressão, método para detecção de lag-3 em uma amostra biológica, e uso das referidas molécula de anticorpo e composição

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BR122024001145A2 true BR122024001145A2 (pt) 2024-02-27

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BR122024001145-0A BR122024001145A2 (pt) 2014-03-14 2015-03-13 Molécula de anticorpo isolada capaz de se ligar a lag-3, seu método de produção, composição farmacêutica, ácidos nucleicos, vetor de expressão, método para detecção de lag-3 em uma amostra biológica, e uso das referidas molécula de anticorpo e composição

Country Status (36)

Country Link
US (5) US20150259420A1 (https=)
EP (2) EP3116909B1 (https=)
JP (4) JP6576962B2 (https=)
KR (3) KR102442436B1 (https=)
CN (2) CN113583129A (https=)
AU (3) AU2015229103C9 (https=)
BR (1) BR122024001145A2 (https=)
CA (1) CA2936962C (https=)
CL (2) CL2016002112A1 (https=)
CR (1) CR20160425A (https=)
CU (1) CU24481B1 (https=)
CY (1) CY1122510T1 (https=)
DK (1) DK3116909T3 (https=)
EA (1) EA201691765A1 (https=)
EC (1) ECSP16081503A (https=)
ES (1) ES2770684T3 (https=)
GT (1) GT201600185A (https=)
HR (1) HRP20192346T1 (https=)
HU (1) HUE048531T2 (https=)
IL (3) IL288012B1 (https=)
JO (1) JOP20150048B1 (https=)
LT (1) LT3116909T (https=)
ME (1) ME03558B (https=)
MX (2) MX389741B (https=)
MY (1) MY187246A (https=)
PE (1) PE20170071A1 (https=)
PH (1) PH12016501545B1 (https=)
PL (1) PL3116909T3 (https=)
PT (1) PT3116909T (https=)
RS (1) RS59853B1 (https=)
SG (1) SG11201605951YA (https=)
SI (1) SI3116909T1 (https=)
TW (4) TWI898718B (https=)
UY (2) UY40389A (https=)
WO (1) WO2015138920A1 (https=)
ZA (1) ZA201604740B (https=)

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