PT2203439E - 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridinil-2'- onas 1',3'-dissubstituídas - Google Patents

4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridinil-2'- onas 1',3'-dissubstituídas Download PDF

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Publication number
PT2203439E
PT2203439E PT08802105T PT08802105T PT2203439E PT 2203439 E PT2203439 E PT 2203439E PT 08802105 T PT08802105 T PT 08802105T PT 08802105 T PT08802105 T PT 08802105T PT 2203439 E PT2203439 E PT 2203439E
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Portugal
Prior art keywords
disorder
mmol
formula
disorders
phenyl
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Application number
PT08802105T
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English (en)
Portuguese (pt)
Inventor
Jose Maria Cid-Nunez
Terry Patrick Finn
Andres Avelino Trabanco-Suarez
Gregor James Macdonald
Guillaume Albert Jacques Duvey
Robert Johannes Luetjens
Original Assignee
Ortho Mcneil Janssen Pharm
Addex Pharmaceuticals Sa
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39930548&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2203439(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Janssen Pharm, Addex Pharmaceuticals Sa filed Critical Ortho Mcneil Janssen Pharm
Publication of PT2203439E publication Critical patent/PT2203439E/pt

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
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PT08802105T 2007-09-14 2008-09-12 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridinil-2'- onas 1',3'-dissubstituídas PT2203439E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07116390 2007-09-14

Publications (1)

Publication Number Publication Date
PT2203439E true PT2203439E (pt) 2011-02-11

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ID=39930548

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PT08802105T PT2203439E (pt) 2007-09-14 2008-09-12 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridinil-2'- onas 1',3'-dissubstituídas

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Country Link
US (6) US9114138B2 (enExample)
EP (1) EP2203439B1 (enExample)
JP (1) JP5133416B2 (enExample)
KR (2) KR101520086B1 (enExample)
CN (2) CN103342695B (enExample)
AR (1) AR068511A1 (enExample)
AT (1) ATE496906T1 (enExample)
AU (1) AU2008297878B2 (enExample)
BR (1) BRPI0816767B8 (enExample)
CA (1) CA2696948C (enExample)
CL (1) CL2008002745A1 (enExample)
CY (1) CY1111219T1 (enExample)
DE (1) DE602008004794D1 (enExample)
DK (1) DK2203439T3 (enExample)
EA (1) EA017648B1 (enExample)
ES (1) ES2356032T3 (enExample)
HR (1) HRP20110278T1 (enExample)
IL (2) IL204032A (enExample)
MX (1) MX2010002536A (enExample)
MY (1) MY152078A (enExample)
NZ (1) NZ584145A (enExample)
PL (1) PL2203439T3 (enExample)
PT (1) PT2203439E (enExample)
RS (1) RS51660B (enExample)
SI (1) SI2203439T1 (enExample)
TW (2) TWI475995B (enExample)
UA (1) UA100126C2 (enExample)
WO (1) WO2009033704A1 (enExample)
ZA (1) ZA201001151B (enExample)

Families Citing this family (27)

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GB0420722D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200900065A (en) * 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
KR20100080597A (ko) 2007-09-14 2010-07-09 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 １,３-이치환된-４-페닐-1ｈ-피리딘-2-온
BRPI0817101A2 (pt) 2007-09-14 2017-05-09 Addex Pharmaceuticals Sa 4-(aril-x-fenil)-1h-piridin-2-onas 1,3-dissubstituídas
DK2203439T3 (da) 2007-09-14 2011-04-18 Ortho Mcneil Janssen Pharm 1',3'-disubstituerede 4-phenyl-3,4,5,6-tetrahydro-2H,1'H-[1,4']-bipyridinyl-2'-oner
MX2010005110A (es) 2007-11-14 2010-09-09 Ortho Mcneil Janssen Pharm Derivados de imidazo[1,2-a]piridina y su uso como moduladores alostericos positivos de los receptores de glutamato metabotropico 2.
AU2009289784B2 (en) 2008-09-02 2012-03-22 Addex Pharma S.A. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
US8697689B2 (en) 2008-10-16 2014-04-15 Janssen Pharmaceuticals, Inc. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
RU2512283C2 (ru) 2008-11-28 2014-04-10 Янссен Фармасьютикалз, Инк. Производные индола и бензоксазина в качестве модуляторов метаботропных глутаматных рецепторов
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