YU63802A - Modulatori adenozinskih receptora - Google Patents

Modulatori adenozinskih receptora

Info

Publication number
YU63802A
YU63802A YU63802A YUP63802A YU63802A YU 63802 A YU63802 A YU 63802A YU 63802 A YU63802 A YU 63802A YU P63802 A YUP63802 A YU P63802A YU 63802 A YU63802 A YU 63802A
Authority
YU
Yugoslavia
Prior art keywords
receptor modulators
adenosine receptor
disease
antiepileptics
ischaemia
Prior art date
Application number
YU63802A
Other languages
English (en)
Inventor
Edilio Maurizio Borroni
Gerda Huber-Trottmann
Gavin John Kilpatrick
Roger David Norcross
Original Assignee
F. Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag. filed Critical F. Hoffmann-La Roche Ag.
Publication of YU63802A publication Critical patent/YU63802A/sh

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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D239/42—One nitrogen atom
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Abstract

Ovaj pronalazak se odnosi na ciklična heteroaromatična jedinjenja koja sadrže najmanje jedan atom azota i na njihovu primenu u proizvodnji lekova za terapiju bolesti koje su u vezi sa modulatorima adenozinskih receptora, kao što su Alchajmerova bolest, Parkinsonova bolest, neurozaštita (neuroprotekcija), shizofrenija, anksioznost, bol, nedostaci respiracije, depresija, astma, alergijski odgovori, hipoksija, ishemija, iznenadni napad bolesti, zloupotreba supstanci, sedacija (smirenje) i ona mogu biti aktivna kao relaksanti mišića, antipsihotici, antiepileptici, antikonvulzanti (sredstva protiv grčeva) kardiozaštitni agensi.[The invention relates to cyclic heteroaromatic compounds, containing at least one nitrogen atom, and to their use in the manufacture of medicaments for the treatment of diseases, related to adenosine receptor modulators, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses, hypoxia, ischaemia, seizure, substance abuse, sedation and they may be active as muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardioprotective agents.
YU63802A 2000-02-25 2001-02-15 Modulatori adenozinskih receptora YU63802A (sh)

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