ATE325115T1 - Pyrimidinderivate als selektive cox-2-inhibitoren - Google Patents

Pyrimidinderivate als selektive cox-2-inhibitoren

Info

Publication number
ATE325115T1
ATE325115T1 AT03792369T AT03792369T ATE325115T1 AT E325115 T1 ATE325115 T1 AT E325115T1 AT 03792369 T AT03792369 T AT 03792369T AT 03792369 T AT03792369 T AT 03792369T AT E325115 T1 ATE325115 T1 AT E325115T1
Authority
AT
Austria
Prior art keywords
inhibitors
pyrimidine derivatives
selective cox
compounds
formula
Prior art date
Application number
AT03792369T
Other languages
English (en)
Inventor
Gordon Weingarten
Gianpaolo Bravi
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0219304A external-priority patent/GB0219304D0/en
Priority claimed from GB0219305A external-priority patent/GB0219305D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE325115T1 publication Critical patent/ATE325115T1/de

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    • C—CHEMISTRY; METALLURGY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychiatry (AREA)
AT03792369T 2002-08-19 2003-08-15 Pyrimidinderivate als selektive cox-2-inhibitoren ATE325115T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0219304A GB0219304D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
GB0219305A GB0219305D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives

Publications (1)

Publication Number Publication Date
ATE325115T1 true ATE325115T1 (de) 2006-06-15

Family

ID=31948026

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03792369T ATE325115T1 (de) 2002-08-19 2003-08-15 Pyrimidinderivate als selektive cox-2-inhibitoren

Country Status (8)

Country Link
US (1) US7235560B2 (de)
EP (1) EP1546128B1 (de)
JP (1) JP2006500372A (de)
AT (1) ATE325115T1 (de)
AU (1) AU2003258630A1 (de)
DE (1) DE60305053T2 (de)
ES (1) ES2263058T3 (de)
WO (1) WO2004018452A1 (de)

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Publication number Priority date Publication date Assignee Title
DE60305053T2 (de) 2002-08-19 2006-08-31 Glaxo Group Ltd., Greenford Pyrimidinderivate als selektive cox-2-inhibitoren
GB0221443D0 (en) 2002-09-16 2002-10-23 Glaxo Group Ltd Pyridine derivates
EP1799196B1 (de) 2004-10-08 2016-06-22 Forward Pharma A/S Pharmazeutische zusammensetzung mit kontrollierter freisetzung mit einem fumarsäureester
EP1931642A4 (de) * 2005-09-15 2011-06-01 Orchid Res Lab Ltd Neue pyrimidincarboxamide
EP1940382A2 (de) * 2005-10-07 2008-07-09 Aditech Pharma AB Kombinationstherapie mit fumarsäureestern zur behandlung von autoimmunkrankheiten und/oder entzündlichen erkrankungen
UA125896C2 (uk) 2009-01-09 2022-07-06 Фвп Іп Апс Фармацевтичний склад, що містить в матриці, яка піддається ерозії, один або більше ефірів фумарової кислоти
EP2547662A4 (de) * 2010-03-17 2013-10-02 Glaxo Group Ltd Pyrimidinderivate zur verwendung als sphingosin-1-phosphat-1 (s1p1)-rezeptoragonisten
AU2017275657B2 (en) 2016-06-02 2021-08-19 Novartis Ag Potassium channel modulators
UA123810C2 (uk) 2017-01-23 2021-06-02 Цадент Терапеутікс, Інк. Модулятори калієвих каналів
MX2021004647A (es) 2018-10-22 2021-08-16 Novartis Ag Formas cristalinas de moduladores de los canales de potasio.
US20220348590A1 (en) * 2019-09-13 2022-11-03 The Board Institute, Inc. Cyclooxygenase-2 inhibitors and uses thereof

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US3149109A (en) 1962-02-20 1964-09-15 Searle & Co Certain 4-trifluoromethyl-2-(oxy/thio) pyrimidines
GB1121922A (en) 1966-06-17 1968-07-31 Ici Ltd Pyrimidine derivatives
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JP2006500372A (ja) 2006-01-05
EP1546128B1 (de) 2006-05-03
DE60305053T2 (de) 2006-08-31
WO2004018452A1 (en) 2004-03-04
US7235560B2 (en) 2007-06-26
AU2003258630A1 (en) 2004-03-11
US20060040967A1 (en) 2006-02-23

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