DE60305053D1 - Pyrimidinderivate als selektive cox-2-inhibitoren - Google Patents

Pyrimidinderivate als selektive cox-2-inhibitoren

Info

Publication number
DE60305053D1
DE60305053D1 DE60305053T DE60305053T DE60305053D1 DE 60305053 D1 DE60305053 D1 DE 60305053D1 DE 60305053 T DE60305053 T DE 60305053T DE 60305053 T DE60305053 T DE 60305053T DE 60305053 D1 DE60305053 D1 DE 60305053D1
Authority
DE
Germany
Prior art keywords
inhibitors
pyrimidine derivatives
selective cox
compounds
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60305053T
Other languages
English (en)
Other versions
DE60305053T2 (de
Inventor
Gordon Weingarten
Gianpaolo Bravi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0219305A external-priority patent/GB0219305D0/en
Priority claimed from GB0219304A external-priority patent/GB0219304D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE60305053D1 publication Critical patent/DE60305053D1/de
Application granted granted Critical
Publication of DE60305053T2 publication Critical patent/DE60305053T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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DE60305053T 2002-08-19 2003-08-15 Pyrimidinderivate als selektive cox-2-inhibitoren Expired - Fee Related DE60305053T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0219305A GB0219305D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
GB0219304 2002-08-19
GB0219305 2002-08-19
GB0219304A GB0219304D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
PCT/EP2003/009153 WO2004018452A1 (en) 2002-08-19 2003-08-15 Pyrimidine derivatives as selective cox-2 inhibitors

Publications (2)

Publication Number Publication Date
DE60305053D1 true DE60305053D1 (de) 2006-06-08
DE60305053T2 DE60305053T2 (de) 2006-08-31

Family

ID=31948026

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60305053T Expired - Fee Related DE60305053T2 (de) 2002-08-19 2003-08-15 Pyrimidinderivate als selektive cox-2-inhibitoren

Country Status (8)

Country Link
US (1) US7235560B2 (de)
EP (1) EP1546128B1 (de)
JP (1) JP2006500372A (de)
AT (1) ATE325115T1 (de)
AU (1) AU2003258630A1 (de)
DE (1) DE60305053T2 (de)
ES (1) ES2263058T3 (de)
WO (1) WO2004018452A1 (de)

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US7235560B2 (en) 2002-08-19 2007-06-26 Glaxo Group Limited Pyrimidine derivative as selective COX-2 inhibitors
GB0221443D0 (en) 2002-09-16 2002-10-23 Glaxo Group Ltd Pyridine derivates
EP2801354B1 (de) 2004-10-08 2017-02-08 Forward Pharma A/S Gesteuerte Freisetzung von pharmazeutischen Zusammensetzungen mit Fumarinsäureester
NZ566722A (en) * 2005-09-15 2010-11-26 Orchid Res Lab Ltd Novel pyrimidine carboxamides
EP1940382A2 (de) * 2005-10-07 2008-07-09 Aditech Pharma AB Kombinationstherapie mit fumarsäureestern zur behandlung von autoimmunkrankheiten und/oder entzündlichen erkrankungen
KR101699912B1 (ko) 2009-01-09 2017-01-25 포워드 파마 에이/에스 1종 이상의 푸마르산 에스테르를 침식 매트릭스에 함유하는 제제
WO2011113309A1 (en) * 2010-03-17 2011-09-22 Glaxo Group Limited Pyrimidine derivatives for use as sphingosine 1-phosphate 1 (s1p1) receptor agonists
AU2017275657B2 (en) 2016-06-02 2021-08-19 Novartis Ag Potassium channel modulators
LT3571193T (lt) 2017-01-23 2022-02-10 Cadent Therapeutics, Inc. Kalio kanalo moduliatoriai
WO2021050700A1 (en) * 2019-09-13 2021-03-18 The Broad Institute, Inc. Cyclooxygenase-2 inhibitors and uses thereof

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Publication number Priority date Publication date Assignee Title
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EP1546128B1 (de) 2006-05-03
WO2004018452A1 (en) 2004-03-04
JP2006500372A (ja) 2006-01-05
US7235560B2 (en) 2007-06-26
US20060040967A1 (en) 2006-02-23
DE60305053T2 (de) 2006-08-31

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