BE790440A
(es)
|
1971-10-23 |
1973-04-24 |
Bayer Ag |
|
US3906953A
(en)
|
1974-05-23 |
1975-09-23 |
American Optical Corp |
Endoscopic surgical laser system
|
SU509578A1
(ru)
|
1974-09-19 |
1976-04-05 |
Стерлитамакский Химический Завод |
Способ получени пропилендиаминов
|
GB1502312A
(en)
|
1975-03-20 |
1978-03-01 |
Ici Ltd |
Quinolone derivatives
|
IE43079B1
(en)
|
1975-03-20 |
1980-12-17 |
Ici Ltd |
Quinolone derivatives
|
FR2311776A1
(fr)
|
1975-05-23 |
1976-12-17 |
Sogeras |
Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation
|
GB1570494A
(en)
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
US4196207A
(en)
|
1977-05-23 |
1980-04-01 |
Ici Australia Limited |
Process for controlling eradicating or preventing infestations of animals by Ixodid ticks
|
DE2750288A1
(de)
|
1977-11-10 |
1979-05-17 |
Thomae Gmbh Dr K |
Neue 9-(omega-heteroarylamino- alkylamino)-erythromycine, ihre salze, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
|
US4358453A
(en)
|
1982-01-08 |
1982-11-09 |
Schering Corporation |
1,2,4-Triazolo[4,3-a]pyridines
|
US4550166A
(en)
|
1984-05-21 |
1985-10-29 |
American Cyanamid Company |
(Pyridinyl)-1,2,4-triazolo[4,3-a]pyridines
|
US5175157A
(en)
|
1985-11-27 |
1992-12-29 |
Boehringer Ingelheim Gmbh |
Cyclic amine derivatives, pharmaceutical compositions containing these compounds and methods for preparing them
|
US4866074A
(en)
|
1987-05-08 |
1989-09-12 |
Rorer Pharmaceutical Corporation |
Naphtheridinone- and pyridooxazinone-pyridone compounds, cardiotonic compositions including same, and their uses
|
US5260293A
(en)
|
1988-01-30 |
1993-11-09 |
Merck Sharp & Dohme Limited |
Pyrazines, pyrimidines and pyridazines useful in the treatment of senile dementia
|
GB8804448D0
(en)
|
1988-02-25 |
1988-03-23 |
Smithkline Beckman Intercredit |
Compounds
|
JP2614081B2
(ja)
|
1988-05-27 |
1997-05-28 |
大塚化学株式会社 |
光学活性β−ラクタム誘導体の製造法
|
US5032602A
(en)
|
1988-12-14 |
1991-07-16 |
Bayer Aktiengesellschaft |
Inhibiting HMG-CoA reductase with novel substituted 2-pyridones and pyrid-2-thiones
|
US5236917A
(en)
|
1989-05-04 |
1993-08-17 |
Sterling Winthrop Inc. |
Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof
|
US5280026A
(en)
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
AU622330B2
(en)
|
1989-06-23 |
1992-04-02 |
Takeda Chemical Industries Ltd. |
Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
|
US4978663A
(en)
|
1989-08-16 |
1990-12-18 |
Hoechst-Roussel Pharmaceuticals Inc. |
5-(1-aminocyclohexyl)-2(1H)-pyridinone compounds which have pharmaceutical utility
|
GB8926560D0
(en)
|
1989-11-24 |
1990-01-17 |
Zambeletti Spa L |
Pharmaceuticals
|
DE3940480A1
(de)
|
1989-12-07 |
1991-06-13 |
Bayer Ag |
Chromogene enaminverbindungen, ihre herstellung und verwendung als farbbildner
|
FR2657610A1
(fr)
|
1990-01-29 |
1991-08-02 |
Rhone Poulenc Agrochimie |
Triazolopyridines herbicides.
|
US5332750A
(en)
|
1991-09-04 |
1994-07-26 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
1,2-dihydro-2-oxopyridines
|
DE4131924A1
(de)
|
1991-09-25 |
1993-07-08 |
Hoechst Ag |
Substituierte 4-alkoxypyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
|
US5204198A
(en)
|
1991-10-28 |
1993-04-20 |
Eastman Kodak Company |
Photoelectrographic elements utilizing nonionic sulfonic acid photogenerators
|
DE4221583A1
(de)
|
1991-11-12 |
1993-05-13 |
Bayer Ag |
Substituierte biphenylpyridone
|
JP2878531B2
(ja)
|
1991-12-16 |
1999-04-05 |
富士写真フイルム株式会社 |
ハロゲン化銀写真感光材料
|
US5378720A
(en)
|
1991-12-19 |
1995-01-03 |
Sterling Winthrop Inc. |
Saccharin derivative proteolytic enzyme inhibitors
|
GB9200293D0
(en)
|
1992-01-08 |
1992-02-26 |
Wyeth John & Brother Ltd |
Piperazine derivatives
|
DE4206045A1
(de)
|
1992-02-27 |
1993-09-02 |
Bayer Ag |
Sulfonylbenzyl substituierte pyridone
|
US5922773A
(en)
|
1992-12-04 |
1999-07-13 |
The Children's Medical Center Corp. |
Glaucoma treatment
|
AU660132B2
(en)
|
1992-12-21 |
1995-06-08 |
Bayer Aktiengesellschaft |
Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridine
|
US5814645A
(en)
|
1993-03-24 |
1998-09-29 |
Bayer Aktiengesellschaft |
Arylor hetaryl substituted nitrogen heterocycles and their use as pesticides
|
DE4316077A1
(de)
|
1993-05-13 |
1994-11-17 |
Bayer Ag |
Substituierte Mono- und Bihydridylmethylpyridone
|
WO1994029273A1
(en)
|
1993-06-09 |
1994-12-22 |
Smithkline Beecham Corporation |
Bicyclic fibrinogen antagonists
|
NZ271994A
(en)
|
1993-08-19 |
1997-06-24 |
Janssen Pharmaceutica Nv |
Aryloxyalkylaminoalkyl-guanidine derivatives, cyclised analogues thereof and medicaments
|
CZ287771B6
(en)
|
1993-08-19 |
2001-01-17 |
Janssen Pharmaceutica Nv |
Dihydrobenzopyran derivatives, process and intermediates for their preparation, their use and pharmaceutical preparations based thereon
|
US5424435A
(en)
|
1993-10-18 |
1995-06-13 |
Olin Corporation |
1-hydroxy-6-substituted-2-pyridones
|
US5500420A
(en)
|
1993-12-20 |
1996-03-19 |
Cornell Research Foundation, Inc. |
Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia
|
US5654307A
(en)
|
1994-01-25 |
1997-08-05 |
Warner-Lambert Company |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
|
US5473077A
(en)
|
1994-11-14 |
1995-12-05 |
Eli Lilly And Company |
Pyrrolidinyl di-carboxylic acid derivatives as metabotropic glutamate receptor agonists
|
US6017697A
(en)
|
1994-11-14 |
2000-01-25 |
Eli Lilly And Company |
Excitatory amino acid receptor protein and related nucleic acid compounds
|
US5512576A
(en)
|
1994-12-02 |
1996-04-30 |
Sterling Winthrop Inc. |
2-substituted 1,2,5,-thiadiazolidin-3-one 1,1-dioxides and compositions and method of use thereof
|
DE19507522C2
(de)
|
1995-03-03 |
2003-05-28 |
Basf Ag |
Verfahren zur Herstellung von 3,4-Dihydroisochinolinverbindungen und 3,4-Dihydroisochinolinium-Salzen
|
US5869428A
(en)
|
1995-03-13 |
1999-02-09 |
Ishihara Sangyo Kaisha Ltd. |
Pyridonesulfonylurea compounds, process for their production and herbicides containing them
|
DE19510965A1
(de)
|
1995-03-24 |
1996-09-26 |
Asta Medica Ag |
Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung
|
US6130217A
(en)
|
1995-09-20 |
2000-10-10 |
Pfizer Inc |
Compounds enhancing antitumor activity of other cytotoxic agents
|
AR004010A1
(es)
|
1995-10-11 |
1998-09-30 |
Glaxo Group Ltd |
Compuestos heterociclicos
|
WO1997028128A1
(en)
|
1996-02-02 |
1997-08-07 |
Zeneca Limited |
Heterocyclic compounds useful as pharmaceutical agents
|
GB9602166D0
(en)
|
1996-02-02 |
1996-04-03 |
Zeneca Ltd |
Aminoheterocyclic derivatives
|
GB9602294D0
(en)
|
1996-02-05 |
1996-04-03 |
Zeneca Ltd |
Heterocyclic compounds
|
US5710274A
(en)
|
1996-02-28 |
1998-01-20 |
Neurogen Corporation |
N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subtype specific ligands
|
US5741798A
(en)
|
1996-06-03 |
1998-04-21 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
2-benzyl-4-sulfonyl-4H-isoquinolin-1,3-diones and their use as antiinflammatory agents
|
DE19632423A1
(de)
|
1996-08-12 |
1998-02-19 |
Merck Patent Gmbh |
Thienopyrimidine
|
ATE230399T1
(de)
|
1996-08-14 |
2003-01-15 |
Astrazeneca Ab |
Substituierte pyrimidinderivate und ihre pharmazeutische anwendung
|
DE19638484A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
DE19638486A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
US6284794B1
(en)
|
1996-11-05 |
2001-09-04 |
Head Explorer Aps |
Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase
|
US5855654A
(en)
|
1997-01-30 |
1999-01-05 |
Rohm And Haas Company |
Pyridazinones as marine antifouling agents
|
FR2759366B1
(fr)
|
1997-02-11 |
1999-04-16 |
Centre Nat Rech Scient |
Composes constituant notamment des effecteurs de recepteurs du systeme nerveux central sensibles aux amino acides neuroexcitateurs, leur preparation et leurs applications biologiques
|
US6262068B1
(en)
|
1997-02-21 |
2001-07-17 |
Bristol-Myers Squibb Company |
Lactam derivatives as antiarrhythmic agents
|
ES2131463B1
(es)
|
1997-04-08 |
2000-03-01 |
Lilly Sa |
Derivados de ciclopropilglicina con propiedades farmaceuticas.
|
DE19728996A1
(de)
|
1997-07-07 |
1999-01-14 |
Basf Ag |
Triazolverbindungen und deren Verwendung
|
SI0891978T1
(en)
|
1997-07-18 |
2002-06-30 |
F. Hoffmann-La Roche Ag |
5H-Thiazolo (3,2-a) pyrimidine derivatives
|
AU743899B2
(en)
|
1997-07-18 |
2002-02-07 |
Georgetown University |
Bicyclic metabotropic glutamate receptor ligands
|
CN1154489C
(zh)
|
1997-08-14 |
2004-06-23 |
弗·哈夫曼-拉罗切有限公司 |
抗神经学疾病的杂环乙烯基醚
|
US6358975B1
(en)
|
1997-08-15 |
2002-03-19 |
Johns Hopkins University |
Method of using selective parp inhibitors to prevent or treat neurotoxicity
|
US20020022636A1
(en)
|
1997-09-03 |
2002-02-21 |
Jia-He Li |
Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
|
US20020028813A1
(en)
|
1997-09-03 |
2002-03-07 |
Paul F. Jackson |
Thioalkyl compounds, methods, and compositions for inhibiting parp activity
|
US6121278A
(en)
|
1997-09-03 |
2000-09-19 |
Guilford Pharmaceuticals, Inc. |
Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity
|
US6465484B1
(en)
|
1997-09-26 |
2002-10-15 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
US6162804A
(en)
|
1997-09-26 |
2000-12-19 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
IL135588A0
(en)
|
1997-10-14 |
2001-05-20 |
Welfide Corp |
Piperazine derivatives and pharmaceutical compositions containing the same
|
US6013672A
(en)
|
1997-12-18 |
2000-01-11 |
Uab Research Foundation |
Agonists of metabotropic glutamate receptors and uses thereof
|
US6664250B2
(en)
|
1998-01-20 |
2003-12-16 |
Bristol-Myers Squibb Co. |
Lactam derivatives as antiarrhythmic agents
|
CA2318800C
(en)
|
1998-01-28 |
2005-12-20 |
Taisho Pharmaceutical Co., Ltd. |
Fluorine-containing amino acid derivatives
|
CA2321153A1
(en)
|
1998-02-17 |
1999-08-19 |
Timothy D. Cushing |
Anti-viral pyrimidine derivatives
|
IL138342A0
(en)
|
1998-03-17 |
2001-10-31 |
Pfizer Prod Inc |
Bicyclo[2.2.1] heptanes and related compounds
|
DE19822198C2
(de)
|
1998-05-16 |
2003-02-13 |
Wella Ag |
Oxonolfarbstoffe enthaltende Mittel und Verfahren zur Erzeugung von semipermanenten Färbungen auf Haaren
|
DE19826671A1
(de)
|
1998-06-16 |
1999-12-23 |
Hoechst Schering Agrevo Gmbh |
1,3-Oxazolin- und 1,3-Thiazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
|
ES2140354B1
(es)
*
|
1998-08-03 |
2000-11-01 |
S A L V A T Lab Sa |
Imidazo (1,2a) azinas sustituidas como inhibidores selectivos de la cox-2.
|
JP2000072751A
(ja)
|
1998-08-26 |
2000-03-07 |
Tanabe Seiyaku Co Ltd |
イソキノリノン誘導体
|
JP2000072731A
(ja)
|
1998-08-31 |
2000-03-07 |
Taisho Pharmaceut Co Ltd |
4−置換−2−アミノビシクロ[3.1.0]ヘキサン−2,6−ジカルボン酸誘導体及び製薬用組成物
|
CA2341865C
(en)
|
1998-08-31 |
2006-01-17 |
Taisho Pharmaceutical Co., Ltd. |
6-fluorobicyclo[3.1.0]hexane derivatives
|
CH694053A5
(de)
|
1998-09-03 |
2004-06-30 |
Hoffmann La Roche |
Verfahren zur Herstellung von 2-Amino-bicyclo[3.1.0]hexan-2,6-dicarbonsäure-Derivaten.
|
US6284759B1
(en)
|
1998-09-30 |
2001-09-04 |
Neurogen Corporation |
2-piperazinoalkylaminobenzo-azole derivatives: dopamine receptor subtype specific ligands
|
PE20001236A1
(es)
|
1998-11-13 |
2000-11-10 |
Lilly Co Eli |
Moduladores del receptor de aminoacidos excitadores
|
US6133271A
(en)
|
1998-11-19 |
2000-10-17 |
Cell Pathways, Inc. |
Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
|
US5948911A
(en)
|
1998-11-20 |
1999-09-07 |
Cell Pathways, Inc. |
Method for inhibiting neoplastic cells and related conditions by exposure to thienopyrimidine derivatives
|
EP1006112A1
(en)
|
1998-12-01 |
2000-06-07 |
Cerebrus Pharmaceuticals Limited |
3-Hydroxy-2(1H)-pyridinone or 3-hydroxy-4(1H)-pyridinone derivatives useful as reactive oxygen species (ROS) scavengers
|
TW564247B
(en)
|
1999-04-08 |
2003-12-01 |
Akzo Nobel Nv |
Bicyclic heteraromatic compound
|
US6972296B2
(en)
|
1999-05-07 |
2005-12-06 |
Encysive Pharmaceuticals Inc. |
Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
|
US6723711B2
(en)
|
1999-05-07 |
2004-04-20 |
Texas Biotechnology Corporation |
Propanoic acid derivatives that inhibit the binding of integrins to their receptors
|
AU5073600A
(en)
|
1999-06-03 |
2000-12-28 |
Lilly, S.A. |
Excitatory amino acid receptor modulators
|
CA2390948A1
(en)
|
1999-06-03 |
2000-12-14 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
JP4783967B2
(ja)
|
1999-07-21 |
2011-09-28 |
大正製薬株式会社 |
含フッ素アミノ酸誘導体を有効成分とする医薬
|
US6660753B2
(en)
|
1999-08-19 |
2003-12-09 |
Nps Pharmaceuticals, Inc. |
Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
|
GB9919778D0
(en)
*
|
1999-08-21 |
1999-10-27 |
Zeneca Ltd |
Chemical compounds
|
AU779874B2
(en)
|
1999-10-15 |
2005-02-17 |
F. Hoffmann-La Roche Ag |
Benzodiazepine derivatives
|
RU2259360C2
(ru)
|
1999-10-15 |
2005-08-27 |
Ф.Хоффманн-Ля Рош Аг |
Производные бензодиазепина и лекарственное средство, их содержащее
|
US6800651B2
(en)
|
2000-02-03 |
2004-10-05 |
Eli Lilly And Company |
Potentiators of glutamate receptors
|
CZ20023199A3
(cs)
|
2000-02-25 |
2003-05-14 |
F. Hoffmann-La Roche Ag |
Modulátory receptoru adenosinu
|
GB0007193D0
(en)
|
2000-03-25 |
2000-05-17 |
Univ Manchester |
Treatment of movrmrnt disorders
|
US6403588B1
(en)
|
2000-04-27 |
2002-06-11 |
Yamanouchi Pharmaceutical Co., Ltd. |
Imidazopyridine derivatives
|
CZ301809B6
(cs)
|
2000-04-28 |
2010-06-30 |
Nihon Nohyaku Co., Ltd. |
Zpusob prípravy 2-halogenbenzoových kyselin a jejich derivátu
|
EP1288199A4
(en)
|
2000-04-28 |
2005-10-12 |
Shionogi & Co |
INHIBITORS OF MMP-12
|
MXPA02011053A
(es)
|
2000-05-11 |
2004-08-19 |
Kenneth Curry |
Compuestos novedosos de carboxi amino espiro (2,4)heptano y derivados de los mismos.
|
US20020009713A1
(en)
|
2000-05-11 |
2002-01-24 |
Miller Freda D. |
Methods for identifying modulators of neuronal growth
|
US7081481B2
(en)
|
2000-05-31 |
2006-07-25 |
Eli Lilly And Company |
Excitatory amino acid receptor modulators
|
US6949571B2
(en)
|
2000-06-12 |
2005-09-27 |
Eisai Co., Ltd. |
1,2-dihydropyridine compounds, process for preparation of the same and use thereof
|
WO2002000715A2
(en)
|
2000-06-27 |
2002-01-03 |
Centre National De La Recherche Scientifique-Cnrs |
Mammal 2p domain mechano-sensitive k+ channel, cloning and applications thereof
|
JP2002012533A
(ja)
|
2000-06-27 |
2002-01-15 |
Kao Corp |
染毛剤組成物
|
JP2002003401A
(ja)
|
2000-06-27 |
2002-01-09 |
Japan Science & Technology Corp |
脳由来神経栄養因子誘導剤
|
WO2002000605A1
(fr)
|
2000-06-28 |
2002-01-03 |
Taisho Pharmaceutical Co., Ltd. |
Nouveaux derives d'acide dicarboxylique
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
US6861530B2
(en)
|
2000-07-07 |
2005-03-01 |
Kyowa Hakko Kogyo Co., Ltd. |
Piperidine derivatives
|
US6599940B2
(en)
|
2000-09-13 |
2003-07-29 |
Georgetown University |
Synthesis of 2-hydroxymethylglutamic acid and congeners thereof
|
JP2002105085A
(ja)
|
2000-09-28 |
2002-04-10 |
Yamanouchi Pharmaceut Co Ltd |
新規イミダゾチアゾール誘導体
|
DE10058663A1
(de)
|
2000-11-25 |
2002-05-29 |
Merck Patent Gmbh |
Verwendung von Thienopyrimidinen
|
JP2002308882A
(ja)
|
2001-02-08 |
2002-10-23 |
Yamanouchi Pharmaceut Co Ltd |
チエノピリミジン誘導体
|
AU2002258400A1
(en)
|
2001-02-16 |
2002-08-28 |
Tularik Inc. |
Methods of using pyrimidine-based antiviral agents
|
ES2360205T3
(es)
|
2001-03-02 |
2011-06-01 |
Agennix Ag |
Sistema de ensayo de tres híbridos.
|
US6596731B2
(en)
*
|
2001-03-27 |
2003-07-22 |
Hoffmann-La Roche Inc. |
Substituted imidazo[1,2-A] pyridine derivatives
|
ATE299868T1
(de)
|
2001-04-12 |
2005-08-15 |
Hoffmann La Roche |
Dihydro-benzo (b) (1,4) diazepin-2-on-derivate als mglur2 antagonisten
|
KR100566178B1
(ko)
|
2001-04-12 |
2006-03-29 |
에프. 호프만-라 로슈 아게 |
mGluR2 길항물질 I로서의디하이드로-벤조[b][1,4]디아제핀-2-온 유도체
|
CZ20033053A3
(en)
|
2001-05-14 |
2004-05-12 |
Bristol@Myersásquibbápharmaácompany |
Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands
|
JP2005500294A
(ja)
|
2001-06-19 |
2005-01-06 |
ブリストル−マイヤーズ スクイブ カンパニー |
ホスホジエステラーゼ7に対するピリミジン阻害剤
|
JP2003012653A
(ja)
|
2001-06-28 |
2003-01-15 |
Yamanouchi Pharmaceut Co Ltd |
キナゾリン誘導体
|
JP2005508904A
(ja)
|
2001-09-11 |
2005-04-07 |
スミスクライン ビーチャム コーポレーション |
血管新生阻害剤としてのフロ−及びチエノピリミジン誘導体
|
AU2002359923B2
(en)
|
2001-12-27 |
2007-12-20 |
Taisho Pharmaceutical Co., Ltd. |
6-fluorobicyclo[3.1.0]hexane derivatives
|
EP1465862A1
(en)
|
2002-01-17 |
2004-10-13 |
SmithKline Beecham Corporation |
Cycloalkyl ketoamides derivatives useful as cathepsin k inhibitors
|
US20050113283A1
(en)
|
2002-01-18 |
2005-05-26 |
David Solow-Cordero |
Methods of treating conditions associated with an EDG-4 receptor
|
US6949542B2
(en)
|
2002-02-06 |
2005-09-27 |
Hoffman-La Roche Inc. |
Dihydro-benzo[b][1,4]diazepin-2-one derivatives
|
US20040116489A1
(en)
|
2002-02-12 |
2004-06-17 |
Massey Steven Marc |
Synthetic excitatory amino acids
|
GEP20063937B
(en)
|
2002-02-14 |
2006-10-10 |
Pharmacia Corp |
Substituted pyridinones as modulators of p38 map kinase
|
US6833380B2
(en)
|
2002-03-07 |
2004-12-21 |
Warner-Lambert Company, Llc |
Compounds that modulate PPAR activity and methods of preparation
|
NZ535438A
(en)
|
2002-03-29 |
2006-08-31 |
Janssen Pharmaceutica Nv |
Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
|
US6864261B2
(en)
|
2002-05-02 |
2005-03-08 |
Euro-Celtique S.A. |
Therapeutic agents useful for treating pain
|
MY141867A
(en)
|
2002-06-20 |
2010-07-16 |
Vertex Pharma |
Substituted pyrimidines useful as protein kinase inhibitors
|
US20060063782A1
(en)
|
2002-07-03 |
2006-03-23 |
Murray Christopher W |
3-Hetero arylmethoxy ! pyridines and their analogues as p38 map kinase inhibitors
|
US7262194B2
(en)
|
2002-07-26 |
2007-08-28 |
Euro-Celtique S.A. |
Therapeutic agents useful for treating pain
|
US20040138238A1
(en)
|
2002-08-08 |
2004-07-15 |
Dhanoa Dale S. |
Substituted aminopyrimidine compounds as neurokinin antagonists
|
GB0218630D0
(en)
|
2002-08-10 |
2002-09-18 |
Tanabe Seiyaku Co |
Novel compounds
|
GB0218800D0
(en)
|
2002-08-13 |
2002-09-18 |
Celltech R&D Ltd |
Chemical compounds
|
WO2004017950A2
(en)
|
2002-08-22 |
2004-03-04 |
Piramed Limited |
Phosphadidylinositol 3,5-biphosphate inhibitors as anti-viral agents
|
AU2003258305A1
(en)
|
2002-08-28 |
2004-03-19 |
Intermune, Inc. |
Combination therapy for treatment of fibrotic disorders
|
MY139563A
(en)
|
2002-09-04 |
2009-10-30 |
Bristol Myers Squibb Co |
Heterocyclic aromatic compounds useful as growth hormone secretagogues
|
US8354447B2
(en)
|
2002-09-10 |
2013-01-15 |
The Scripps Research Institute |
mGLU receptors antagonists for treating disorders associated with mGLU receptors including addiction and depression
|
EP1546201A4
(en)
|
2002-09-11 |
2006-08-16 |
Merck & Co Inc |
NUCLEIC ACID SEQUENCES CODING TO MGLUR2 AND MGLUR3 FOR NEW POINT MUTATIONS
|
AU2003269628A1
(en)
|
2002-09-19 |
2004-04-08 |
Boehringer Ingelheim (Canada) Ltd. |
Non-nucleoside reverse transcriptase inhibitors
|
ES2268499T3
(es)
|
2002-09-19 |
2007-03-16 |
Boehringer Ingelheim (Canada) Ltd. |
Inhibidores no nucleosidos de transcriptasa inveresa.
|
TW200410975A
(en)
|
2002-09-26 |
2004-07-01 |
Nihon Nohyaku Co Ltd |
New pesticide and method for using it, new substituted thienopyrimidine derivative, its intermediate, and method for producing it
|
US7067658B2
(en)
|
2002-09-30 |
2006-06-27 |
Bristol-Myers Squibb Company |
Pyridino and pyrimidino pyrazinones
|
US7998163B2
(en)
|
2002-10-03 |
2011-08-16 |
Boston Scientific Scimed, Inc. |
Expandable retrieval device
|
DE60330376D1
(de)
|
2002-10-23 |
2010-01-14 |
Daiichi Pure Chemicals Co Ltd |
Defructosylierungsverfahren
|
US20040138204A1
(en)
|
2002-10-30 |
2004-07-15 |
Harrington James Frederick |
Compositions and methods for pain reduction
|
MXPA05004670A
(es)
|
2002-11-01 |
2005-08-18 |
Abbott Lab |
Agentes anti-infecciones.
|
US7902203B2
(en)
|
2002-11-01 |
2011-03-08 |
Abbott Laboratories, Inc. |
Anti-infective agents
|
US6930117B2
(en)
|
2002-11-09 |
2005-08-16 |
The Procter & Gamble Company |
N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones
|
AU2003295776B2
(en)
|
2002-11-21 |
2011-05-12 |
Novartis Vaccines And Diagnostics, Inc. |
2,4,6-trisubstituted pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer
|
WO2004054979A1
(ja)
|
2002-12-18 |
2004-07-01 |
Takeda Pharmaceutical Company Limited |
Jnk阻害剤
|
CN1802353A
(zh)
|
2002-12-30 |
2006-07-12 |
细胞基因公司 |
氟烷氧基取代的1,3-二氢-异吲哚化合物及其药物用途
|
EP1599468B1
(en)
|
2003-01-14 |
2007-10-03 |
Arena Pharmaceuticals, Inc. |
1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
ITMI20030151A1
(it)
|
2003-01-30 |
2004-07-31 |
Recordati Ind Chimica E Farma Ceutica S P A |
Uso di antagonisti selettivi del recettore mglu5 per il trattamento di disfunzioni neuromuscolari del tratto urinario inferiore.
|
PL378405A1
(pl)
|
2003-02-04 |
2006-04-03 |
F. Hoffmann-La Roche Ag |
Pochodne malonoamidu jako inhibitory <$Egamma> - sekretazy
|
DE10306250A1
(de)
|
2003-02-14 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US20070066590A1
(en)
|
2003-02-24 |
2007-03-22 |
Jones Robert M |
Phenyl-and pyridylpiperidine-derivatives as modulators of glucose metabolism
|
WO2004078176A1
(en)
|
2003-03-03 |
2004-09-16 |
F. Hoffmann-La Roche Ag |
2,5- and 2,6-substituted tetrahydroisoquinolines for use as 5-ht6 modulators
|
ITFI20030058A1
(it)
|
2003-03-06 |
2004-09-07 |
Univ Firenze |
Formulazioni farmaceutiche contenenti tiazolidinedioni
|
DE10311065A1
(de)
|
2003-03-13 |
2004-09-23 |
Abbott Gmbh & Co. Kg |
Pyrimidin-2-on-Verbindungen und ihre therapeutische Verwendung
|
WO2004092123A2
(en)
|
2003-04-10 |
2004-10-28 |
Microbia, Inc. |
Inhibitors of fungal invasion
|
JP2004339080A
(ja)
|
2003-05-13 |
2004-12-02 |
Tokyo Institute Of Technology |
ピラゾ−ル誘導体を含有する高血圧治療剤
|
BRPI0410348A
(pt)
|
2003-05-14 |
2006-05-30 |
Torreypines Therapeutics Inc |
compostos e usos dos mesmos na modulação de amilóide-beta
|
JP2007504283A
(ja)
|
2003-05-20 |
2007-03-01 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
β−アミロイド斑に作用物質を結合させる方法
|
GB0315950D0
(en)
|
2003-06-11 |
2003-08-13 |
Xention Discovery Ltd |
Compounds
|
EP1680125A1
(en)
|
2003-07-02 |
2006-07-19 |
Warner-Lambert Company LLC |
Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
|
WO2005007144A2
(en)
|
2003-07-14 |
2005-01-27 |
Decode Genetics Ehf |
Method of diagnosis and treatment for asthma based on haplotype association
|
CA2535416A1
(en)
*
|
2003-08-15 |
2005-02-24 |
Banyu Pharmaceutical Co., Ltd. |
Imidazopyridine derivatives
|
GB0320300D0
(en)
|
2003-08-29 |
2003-10-01 |
Cancer Rec Tech Ltd |
Pyrimidothiophene compounds
|
BRPI0413861A
(pt)
|
2003-08-29 |
2006-10-24 |
Vernalis Cambridge Ltd |
compostos de pirimidotiofeno
|
GB0322016D0
(en)
|
2003-09-19 |
2003-10-22 |
Merck Sharp & Dohme |
New compounds
|
AU2005214379B2
(en)
|
2004-02-18 |
2012-03-22 |
Astrazeneca Ab |
Tetrazole compounds and their use as metabotropic glutamate receptor antagonits
|
DE102004009039A1
(de)
|
2004-02-23 |
2005-09-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
|
US7306631B2
(en)
|
2004-03-30 |
2007-12-11 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
US20070219234A1
(en)
|
2004-04-12 |
2007-09-20 |
Kiyoshi Oizumi |
Thienopyridine Derivatives
|
US7459562B2
(en)
|
2004-04-23 |
2008-12-02 |
Bristol-Myers Squibb Company |
Monocyclic heterocycles as kinase inhibitors
|
GB0413605D0
(en)
|
2004-06-17 |
2004-07-21 |
Addex Pharmaceuticals Sa |
Novel compounds
|
US8063004B2
(en)
|
2004-07-22 |
2011-11-22 |
Malcera, L.L.C. |
Chemical composition of matter for the liquefaction and dissolution of asphaltene and paraffin sludges into petroleum crude oils and refined products at ambient temperatures and method of use
|
CA2568850A1
(en)
|
2004-08-02 |
2006-02-16 |
Schwarz Pharma Ag |
Indolizine carboxamides and the aza and diaza derivatives thereof
|
JP5276322B2
(ja)
|
2004-08-11 |
2013-08-28 |
コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ |
虚血性心疾患の超音波診断方法及び装置
|
TW200613272A
(en)
|
2004-08-13 |
2006-05-01 |
Astrazeneca Ab |
Isoindolone compounds and their use as metabotropic glutamate receptor potentiators
|
EP1781655A2
(en)
|
2004-08-18 |
2007-05-09 |
Pharmacia & Upjohn Company LLC |
Triazolopyridine compounds useful for the treatment of inflammation
|
DE102004044884A1
(de)
*
|
2004-09-14 |
2006-05-24 |
Grünenthal GmbH |
Substituierte bizyklische Imidazo-3-yl-amin-Verbindungen
|
GB0420722D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
US7434262B2
(en)
|
2004-12-08 |
2008-10-07 |
At&T Intellectual Property I, L.P. |
Methods and systems that selectively resurrect blocked communications between devices
|
DE102004061288A1
(de)
|
2004-12-14 |
2006-06-29 |
Schering Ag |
3-Amino-Pyrazolo[3,4b]pyridine als Inhibitoren von Proteintyrosinkinasen, deren Herstellung und Verwendung als Arzneimittel
|
US7456289B2
(en)
|
2004-12-31 |
2008-11-25 |
National Health Research Institutes |
Anti-tumor compounds
|
KR100968989B1
(ko)
*
|
2005-03-23 |
2010-07-09 |
에프. 호프만-라 로슈 아게 |
mGluR2 길항제로서 아세틸렌일-피라졸로-피리미딘 유도체
|
US7579360B2
(en)
|
2005-06-09 |
2009-08-25 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US7572807B2
(en)
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
US20080318999A1
(en)
|
2005-08-05 |
2008-12-25 |
Methvin Isaac |
Tricyclic Benzimidazoles and Their Use as Metabotropic Glutamate Receptor Modulators
|
WO2007027669A1
(en)
|
2005-08-29 |
2007-03-08 |
Cps Biofuels, Inc. |
Improved biodiesel fuel, additives, and lubbricants
|
EP1948654B1
(en)
|
2005-09-17 |
2009-06-24 |
Novartis Ag |
5-amino-4-hydroxy-7- (imidazo [1,2-a] pyridin-6- ylmethyl)-8-methyl-nonamide derivatives and related compounds as renin inhibitors for the treatment of hypertension
|
EP1764099A3
(en)
|
2005-09-17 |
2007-05-09 |
Speedel Experimenta AG |
Diaminoalcohol derivatives for the treatment of Alzheimer, malaria, HIV
|
CN101273040B
(zh)
*
|
2005-09-27 |
2011-11-09 |
弗·哈夫曼-拉罗切有限公司 |
作为mglur2拮抗剂的*二唑基吡唑并嘧啶类化合物
|
CA2755268C
(en)
|
2005-11-15 |
2013-12-31 |
Array Biopharma, Inc. |
Erbb inhibitors
|
WO2007103760A2
(en)
|
2006-03-02 |
2007-09-13 |
Smithkline Beecham Corporation |
Thiazolones for use as pi3 kinase inhibitors
|
TWI417095B
(zh)
|
2006-03-15 |
2013-12-01 |
Janssen Pharmaceuticals Inc |
1,4-二取代之3-氰基-吡啶酮衍生物及其作為mGluR2-受體之正向異位性調節劑之用途
|
GB0606774D0
(en)
|
2006-04-03 |
2006-05-10 |
Novartis Ag |
Organic compounds
|
GB0608263D0
(en)
|
2006-04-26 |
2006-06-07 |
Glaxo Group Ltd |
Compounds
|
WO2007135527A2
(en)
|
2006-05-23 |
2007-11-29 |
Pfizer Products Inc. |
Benzimidazolyl compounds
|
WO2007135529A2
(en)
|
2006-05-23 |
2007-11-29 |
Pfizer Products Inc. |
Azabenzimidazolyl compounds as mglur2 potentiators
|
JP5228911B2
(ja)
|
2006-06-19 |
2013-07-03 |
東レ株式会社 |
多発性硬化症の治療又は予防剤
|
WO2008006540A1
(en)
|
2006-07-12 |
2008-01-17 |
Syngenta Participations Ag |
Triazolopyridine derivatives as herbicides
|
PE20121506A1
(es)
|
2006-07-14 |
2012-11-26 |
Amgen Inc |
Compuestos triazolopiridinas como inhibidores de c-met
|
US8198448B2
(en)
|
2006-07-14 |
2012-06-12 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
WO2008012622A2
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Azabenzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
ATE542818T1
(de)
|
2006-10-11 |
2012-02-15 |
Amgen Inc |
Imidazo- und triazolopyridinverbindungen und verfahren zu deren anwendung
|
WO2008057855A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
Heterocyclic compounds as modulators of glucocorticoid receptor, ap-i, and/or np-kappa-b activity
|
TW200831085A
(en)
|
2006-12-13 |
2008-08-01 |
Merck & Co Inc |
Non-nucleoside reverse transcriptase inhibitors
|
JP5442449B2
(ja)
|
2006-12-22 |
2014-03-12 |
アステックス、セラピューティックス、リミテッド |
新規化合物
|
US8895745B2
(en)
|
2006-12-22 |
2014-11-25 |
Astex Therapeutics Limited |
Bicyclic heterocyclic compounds as FGFR inhibitors
|
ES2320955B1
(es)
|
2007-03-02 |
2010-03-16 |
Laboratorios Almirall S.A. |
Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
|
MX2009009519A
(es)
|
2007-03-07 |
2009-11-18 |
Janssen Pharmaceutica Nv |
Fenoxitiazolidinodionas n-alquiladas sustituidas como moduladores de receptor- alfa relacionados con estrogeno.
|
CN101679322A
(zh)
|
2007-03-07 |
2010-03-24 |
詹森药业有限公司 |
用作雌激素相关性受体-α调节剂的取代苯氧基噻唑烷二酮类化合物
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
GB0704407D0
(en)
|
2007-03-07 |
2007-04-18 |
Glaxo Group Ltd |
Compounds
|
TW200845978A
(en)
|
2007-03-07 |
2008-12-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
|
TW200900391A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-phenyl-piperidin-1-yl)-pyridin-2-one derivatives
|
MX2009009520A
(es)
|
2007-03-07 |
2009-11-18 |
Janssen Pharmaceutica Nv |
Fenoxiaminotiazolonas sustituidas como moduladores del receptor alfa relacionados con estrogenos.
|
WO2008124085A2
(en)
|
2007-04-03 |
2008-10-16 |
Exelixis, Inc. |
Methods of using combinations of mek and jak-2 inhibitors
|
TWI417100B
(zh)
|
2007-06-07 |
2013-12-01 |
Astrazeneca Ab |
二唑衍生物及其作為代謝型麩胺酸受體增效劑-842之用途
|
TW200922566A
(en)
|
2007-09-14 |
2009-06-01 |
Ortho Mcneil Janssen Pharm |
1,3 disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones
|
TWI445532B
(zh)
|
2007-09-14 |
2014-07-21 |
Janssen Pharmaceuticals Inc |
1’,3’-二取代-4-苯基-3,4,5,6-四氫-2h,1’h-〔1,4’〕聯吡啶基-2’-酮化物
|
JP5433579B2
(ja)
|
2007-09-14 |
2014-03-05 |
ジャンセン ファーマシューティカルズ, インコーポレイテッド. |
1,3−二置換−4−フェニル−1h−ピリジン−2−オン
|
US8119658B2
(en)
|
2007-10-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
ES2637794T3
(es)
|
2007-11-14 |
2017-10-17 |
Janssen Pharmaceuticals, Inc. |
Derivados de imidazo[1,2-A]piridina y su uso como moduladores alostéricos positivos de receptores MGLUR2
|
WO2009094265A1
(en)
|
2008-01-24 |
2009-07-30 |
Merck & Co., Inc. |
3,5-substituted-1,3-oxazolidin-2-one derivatives
|
DE102008001056A1
(de)
|
2008-04-08 |
2009-10-15 |
Robert Bosch Gmbh |
Umlenkeinrichtung für einen Strahl einer elektromagnetischen Welle
|
UY32049A
(es)
|
2008-08-14 |
2010-03-26 |
Takeda Pharmaceutical |
Inhibidores de cmet
|
TWI496779B
(zh)
|
2008-08-19 |
2015-08-21 |
Array Biopharma Inc |
作為pim激酶抑制劑之三唑吡啶化合物
|
WO2010022081A1
(en)
|
2008-08-19 |
2010-02-25 |
Array Biopharma Inc. |
Triazolopyridine compounds as pim kinase inhibitors
|
CA2735764C
(en)
|
2008-09-02 |
2016-06-14 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
|
ES2466341T3
(es)
|
2008-10-16 |
2014-06-10 |
Janssen Pharmaceuticals, Inc. |
Derivados de indol y benzomorfolina como moduladores de receptores de glutamato metabotrópicos
|
WO2010060589A1
(en)
|
2008-11-28 |
2010-06-03 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
|
AT507619B1
(de)
|
2008-12-05 |
2011-11-15 |
Oesterreichisches Forschungs Und Pruefzentrum Arsenal Ges M B H |
Verfahren zur approximation des zeitlichen verlaufs von verkehrsdaten
|
CA2744946A1
(en)
|
2009-02-04 |
2010-08-12 |
Boehringer Ingelheim International Gmbh |
Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
|
EP2417135A1
(en)
|
2009-04-07 |
2012-02-15 |
Schering Corporation |
Substituted triazolopyridines and analogs thereof
|
MY153913A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
SG176018A1
(en)
|
2009-05-12 |
2011-12-29 |
Janssen Pharmaceuticals Inc |
1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
MX2011011964A
(es)
|
2009-05-12 |
2012-02-23 |
Janssen Pharmaceuticals Inc |
Derivados de 1,2,3-triazolo[4,3-a]piridina y su uso para el tratamiento o prevencion de trastornos neurologicos y psiquiatricos.
|
CN102002040A
(zh)
|
2009-09-01 |
2011-04-06 |
上海药明康德新药开发有限公司 |
一种三唑并吡啶环化合物的合成方法
|
JP5204071B2
(ja)
|
2009-09-25 |
2013-06-05 |
パナソニック株式会社 |
電気かみそり
|
US8664214B2
(en)
|
2010-03-30 |
2014-03-04 |
AbbVie Deutschland GmbH & Co. KG |
Small molecule potentiators of metabotropic glutamate receptors I
|
US8314120B2
(en)
|
2010-03-30 |
2012-11-20 |
Abbott Gmbh & Co. Kg |
Small molecule potentiators of metabotropic glutamate receptors
|
CN101893589B
(zh)
|
2010-06-29 |
2012-10-17 |
中国人民解放军第三0二医院 |
一种无菌检查方法及其使用的全封闭集菌安瓿培养器
|
US8785481B2
(en)
|
2010-09-29 |
2014-07-22 |
Merck Sharp & Dohme Corp. |
Ether benzotriazole derivatives
|
JP5852666B2
(ja)
|
2010-11-08 |
2016-02-03 |
ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド |
1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
|
ES2536433T3
(es)
|
2010-11-08 |
2015-05-25 |
Janssen Pharmaceuticals, Inc. |
Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
|
PL2649069T3
(pl)
|
2010-11-08 |
2016-01-29 |
Janssen Pharmaceuticals Inc |
Pochodne 1,2,4-triazolo[4,3-a]pirydyny i ich zastosowanie jako dodatnich allosterycznych modulatorów receptorów mGluR2
|
EP2638040A1
(en)
|
2010-11-08 |
2013-09-18 |
Janssen Pharmaceuticals, Inc. |
RADIOLABELLED mGLuR2 PET LIGANDS
|